Among patients diagnosed with malignant cancers worldwide, 3% to 10% are under 40 years of age. Cancer in reproductive age is twice as frequent in females than in males [1,2]. Important advances in cancer treatments have led to increased survival rates over the past years; conversely these therapies expose patients to potential long term adverse effects, including infertility [3]. The maintenance of future fertility is considered of great importance by patients. At the time of cancer diagnosis, approximately half of the women are concerned about the potential loss of ovarian function and fertility due to use of cancer treatments [4]; moreover, fertility concerns can also influence their therapeutic decisions and the adherence to the suggested treatment [4,5].
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