Παρασκευή, 13 Δεκεμβρίου 2019

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,00306932607174,alsfakia@gmail.com, Telephone consultation 11855 int 1193,


P2Y2 Nucleotide Receptor Is a Regulator of the Formation of Cardiac Adipose Tissue and Its Fat-Associated Lymphoid Clusters
P2Y2 Nucleotide Receptor Is a Regulator of the Formation of Cardiac Adipose Tissue and Its Fat-Associated Lymphoid Clusters: Stem Cells and Development, Ahead of Print. AbstractThe formation of pericardial adipose tissue (PAT) and its regulatory function in cardiac inflammation are not well understood. We investigated the potential role of the ubiquitous ATP/UTP nucleotide receptor P2Y2 in the PAT by using P2Y2-null mice. We observed that P2Y2-null mice displayed a lower mass of PAT and a reduced...
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10:02
Feature extraction and classification of heart sound using 1D convolutional neural networks
Feature extraction and classification of heart sound using 1D convolutional neural networks: AbstractWe proposed a one-dimensional convolutional neural network (CNN) model, which divides heart sound signals into normal and abnormal directly independent of ECG. The deep features of heart sounds were extracted by the denoising autoencoder (DAE) algorithm as the input feature of 1D CNN. The experimental results showed that the model using deep features has stronger anti-interference ability than...
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10:00
Label-free separation and culture of tumor cells in a microfluidic biochip
Label-free separation and culture of tumor cells in a microfluidic biochip: Analyst, 2020, Accepted ManuscriptDOI: 10.1039/C9AN02092F, PaperJian Zhou, Chunlong Tu, Yitao Liang, Bobo Huang, Yifeng Fang, Xiao Liang, Xuesong YeCirculating tumor cell (CTC) of liquid biopsy has shown its strong correlation to clinical outcome of cancer patients. Enumeration and cytological analysis of CTCs have drawn increasing effort for cancer...The content of this RSS Feed (c) The Royal Society of Chemistry
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09:58
Proposed Classification of Incision Complications: Analysis of a Prospective Study on Elective Open Lower-Limb Revascularization
Proposed Classification of Incision Complications: Analysis of a Prospective Study on Elective Open Lower-Limb Revascularization: Surgical Infections, Ahead of Print. AbstractBackground: Incision complications (IC) have a significant impact on procedure-related morbidity after lower-limb revascularization. One of the most studied IC is surgical site infection (SSI). Reporting these complications in a uniform way is crucial to evaluate treatment approaches. The aim of this study was to propose a comprehensive...
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09:57
Reining in Sternal Wound Infections: The Achilles' Heel of Bilateral Internal Thoracic Artery Grafting
Reining in Sternal Wound Infections: The Achilles' Heel of Bilateral Internal Thoracic Artery Grafting: Surgical Infections, Ahead of Print. Background: Although the survival advantage of bilateral internal thoracic artery grafting (BITA) is well known in patients undergoing coronary artery bypass grafting (CABG), this technique has not been widely adopted. This is mainly because of the increased risk of deep sternal wound infections (DSWI) associated with its use. However, in recent years the overall...
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09:57
Erythroferrone, the new iron regulator
Erythroferrone, the new iron regulator: evaluation of its levels in Egyptian patients with beta thalassemia: AbstractSince iron overload is the commonest cause of morbidity and mortality in β thalassemia major (β-TM), it represents one major target in therapeutic management of the disease. The recently discovered erythroid regulator, erythroferrone (ERFE), governed by high levels of erythropoietin, was found to suppress hepcidin expression, thus increasing iron availability for developing erythroid...
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09:56
Transmembrane protease serine 5: a novel Schwann cell plasma marker for CMT1A
Transmembrane protease serine 5: a novel Schwann cell plasma marker for CMT1A: AbstractObjectiveDevelopment of biomarkers for Charcot‐Marie‐Tooth (CMT) disease is critical for implementing effective clinical trials. The most common form of CMT, type 1A, is caused by a genomic duplication surrounding the PMP22 gene. A recent report (Neurology 2018;90:e518–3524) showed elevation of neurofilament light (NfL) in plasma of CMT1A disease patients, which correlated with disease severity. However, no plasma/serum...
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09:56
Fluoride-Contaminated Groundwater and Sodium Fluoride-Induced Reproductive Toxicity and Its Reversibility
A Comparative Analysis of Fluoride-Contaminated Groundwater and Sodium Fluoride-Induced Reproductive Toxicity and Its Reversibility in Male Rats: AbstractThe present study was undertaken to investigate the toxic effect of sodium fluoride (NaF)- and fluoride (F)-contaminated groundwater on male reproduction and it's reversibility in male rats. Adult male rats were orally treated with different concentrations of NaF- (1 mg, 5 mg, and 10 mg/kg/bw/rat) and F-contaminated groundwater for 52 days and after...
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09:55
Trastuzumab in combination with AT-101 induces cytotoxicity and apoptosis in Her2 positive breast cancer cells.........................................Summary points The HER2 oncogene is overexpressed in 25–30% of all breast cancer cases and over expression of this oncogene is closely related to shortened disease-free survival. Treatment of these cancers is based on targeted drugs or combinations. Trastuzumab is a monoclonal targeted agent against HER2. The most important problem of trastuzumab is drug resistance, which may be primary or secondary. Thus, novel treatment options are required to break resistance mechanisms. AT-101(-/-Gossypol) is a polyphenolic compound having potent antiproliferative and apoptotic effects in various cancers. AT-101 also has been studied in breast cancer cell lines and demonstrated apoptotic effect of drug. In this cell culture study, two breast cancer cell lines (MDA-MB453 and SKBR-3), in which HER-2 is overexpressed, were used and MCF-10A was used as a control cell line. The drugs were applied to these cell lines alone or in combination and the effects of the drugs on the cells were investigated. Trastuzumab/AT101 combination showed a synergistic cytotoxic and apoptotic effect on both HER-2 positive breast cancer cell lines but not on control cells. Two pathways were studied that cause this effect. Combination treatment induced cytotoxicity via inhibiting PI3K/AKT but not the MAPK/ERK pathway. Trastuzumab/AT-101 combination may be a good candidate for patients with trastuzumab-resistant HER-2-positive breast cancer.
Trastuzumab in combination with AT-101 induces cytotoxicity and apoptosis in Her2 positive breast cancer cells: Future Oncology, Ahead of Print. Aim: AT-101 is a polyphenolic compound with potent anti-apoptotic effects in various cancers. In this study, the possible synergistic cytotoxic and apoptotic effect of trastuzumab/AT-101 combination was investigated in HER2-positive breast cancer cell lines. Materials & methods: SKBR-3, MDA-MB-453 and MCF-10A cell lines were treated with a trastuzumab/AT-101...
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09:54
Atezolizumab for use in PD-L1-positive unresectable, locally advanced or metastatic triple-negative breast cancer
Atezolizumab for use in PD-L1-positive unresectable, locally advanced or metastatic triple-negative breast cancer: Future Oncology, Ahead of Print. Since the US FDA-approval of the first immune checkpoint inhibitor, anticytotoxic T-lymphocyte antigen-4 monoclonal antibody ipilimumab, for metastatic melanoma on 28 March 2011, another six agents have been granted use among a multitude of tumors, including renal cell cancer, Hodgkin lymphoma, urothelial carcinoma and non-small-cell lung cancer. The...
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09:52
Early tongue carcinomas (clinical stage I and II): echo-guided three-dimensional diode laser mini-invasive surgery with evaluation of histological prognostic parameters. A study of 85 cases with prolonged follow-up
Early tongue carcinomas (clinical stage I and II): echo-guided three-dimensional diode laser mini-invasive surgery with evaluation of histological prognostic parameters. A study of 85 cases with prolonged follow-up: AbstractThe management of patients with early stage (cT1–T2) tongue squamous cell carcinoma without clinicoradiologic evidence of neck node metastasis (cN0) has been widely debated over the last 3 decades and still remains controversial. Nevertheless, the identification of patients with...
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09:52
Long-Term Safety and Effectiveness of Diquafosol for the Treatment of Dry Eye in a Real-World Setting: A Prospective Observational Study
Long-Term Safety and Effectiveness of Diquafosol for the Treatment of Dry Eye in a Real-World Setting: A Prospective Observational Study: AbstractIntroductionDiquafosol is a P2Y2 receptor agonist that has been shown to be effective in the treatment of dry eye disease (DED) in short-term studies; however, its long-term safety and effectiveness have not been evaluated in a real-world setting.MethodsThis prospective, multicentre, open-label observational study was conducted in patients with DED over...
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09:51
Pembrolizumab Combined with Chemoradiotherapy as Initial Treatment for Anaplastic Thyroid Cancer
The Long Road Ahead: A Phase 2 Study of Pembrolizumab Combined with Chemoradiotherapy as Initial Treatment for Anaplastic Thyroid Cancer: Clinical Thyroidology, Volume 31, Issue 12, Page 537-539, December 2019.
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09:50
Risks of Antithyroid Drug-Induced Severe Liver Injury
Risks of Antithyroid Drug-Induced Severe Liver Injury: Clinical Thyroidology, Volume 31, Issue 12, Page 515-519, December 2019.
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09:50
Aggressive Variants of Papillary Thyroid Cancer Impact Survival for Only Invasive Cases
Aggressive Variants of Papillary Thyroid Cancer Impact Survival for Only Invasive Cases: Clinical Thyroidology, Volume 31, Issue 12, Page 530-532, December 2019.
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09:49
Treatment of Hyperthyroidism Is Associated with an Increased Risk of Developing Obesity
Treatment of Hyperthyroidism Is Associated with an Increased Risk of Developing Obesity: Clinical Thyroidology, Volume 31, Issue 12, Page 512-514, December 2019.
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09:48
New Frailty Risk Model Is the Best Yet for Patients Undergoing Thyroid or Parathyroid Surgery
New Frailty Risk Model Is the Best Yet for Patients Undergoing Thyroid or Parathyroid Surgery: Clinical Thyroidology, Volume 31, Issue 12, Page 524-526, December 2019.
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09:48
Levothyroxine for Subclinical Hypothyroidism Does Not Improve Thyroid-Related Symptoms in Patients 80 Years of Age or Older
Levothyroxine for Subclinical Hypothyroidism Does Not Improve Thyroid-Related Symptoms in Patients 80 Years of Age or Older: Clinical Thyroidology, Volume 31, Issue 12, Page 509-511, December 2019.
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09:47
No Increased Risks of Abortion, Preterm Delivery, or Congenital Malformation at 6 Months After Radioactive Iodine Treatment for Thyroid Cancer
No Increased Risks of Abortion, Preterm Delivery, or Congenital Malformation at 6 Months After Radioactive Iodine Treatment for Thyroid Cancer: Clinical Thyroidology, Volume 31, Issue 12, Page 533-536, December 2019.
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09:46
Evaluation of Five Ultrasound Risk-Stratification Systems for Choosing Thyroid Nodules for Fine-Needle Aspiration
Evaluation of Five Ultrasound Risk-Stratification Systems for Choosing Thyroid Nodules for Fine-Needle Aspiration: Clinical Thyroidology, Volume 31, Issue 12, Page 520-523, December 2019.
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09:46
Usefulness of Mesenchymal Cell Lines for Bone and Cartilage Regeneration Research
IJMS, Vol. 20, Pages 6286: Usefulness of Mesenchymal Cell Lines for Bone and Cartilage Regeneration Research: IJMS, Vol. 20, Pages 6286: Usefulness of Mesenchymal Cell Lines for Bone and Cartilage Regeneration ResearchInternational Journal of Molecular Sciences doi: 10.3390/ijms20246286Authors: M. Piñeiro-Ramil C. Sanjurjo-Rodríguez R. Castro-Viñuelas S. Rodríguez-Fernández I.M. Fuentes-Boquete F.J. Blanco S.M. Díaz-Prado The unavailability of sufficient numbers of human primary...
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09:45
Impact of cervical sagittal parameters and spinal cord morphology in cervical spondylotic myelopathy status post spinous process-splitting laminoplasty
Impact of cervical sagittal parameters and spinal cord morphology in cervical spondylotic myelopathy status post spinous process-splitting laminoplasty: AbstractPurposeNo standard strategy exists for managing cervical spondylotic myelopathy (CSM). The efficacy of spinous process-splitting laminoplasty, its impact on cervical alignment change and the incidence of postoperative neck pain remain unclear. We analyzed the parameters of cervical alignment and cord morphology in CSM.MethodsThe radiographic...
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09:43
Alteration of GABAergic Input Precedes Neurodegeneration of Cerebellar Purkinje Cells of NPC1-Deficient Mice
IJMS, Vol. 20, Pages 6288: Alteration of GABAergic Input Precedes Neurodegeneration of Cerebellar Purkinje Cells of NPC1-Deficient Mice: IJMS, Vol. 20, Pages 6288: Alteration of GABAergic Input Precedes Neurodegeneration of Cerebellar Purkinje Cells of NPC1-Deficient MiceInternational Journal of Molecular Sciences doi: 10.3390/ijms20246288Authors: Michael Rabenstein Nico Murr Andreas Hermann Arndt Rolfs Moritz J. Frech Niemann-Pick Disease Type C1 (NPC1) is a rare hereditary neurodegenerative...
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09:42
Expression Profile of the Chromosome 14 MicroRNA Cluster (C14MC) Ortholog in Equine Maternal Circulation throughout Pregnancy and Its Potential Implications
IJMS, Vol. 20, Pages 6285: Expression Profile of the Chromosome 14 MicroRNA Cluster (C14MC) Ortholog in Equine Maternal Circulation throughout Pregnancy and Its Potential Implications: IJMS, Vol. 20, Pages 6285: Expression Profile of the Chromosome 14 MicroRNA Cluster (C14MC) Ortholog in Equine Maternal Circulation throughout Pregnancy and Its Potential ImplicationsInternational Journal of Molecular Sciences doi: 10.3390/ijms20246285Authors: Pouya Dini Hossam El-Sheikh Ali Mariano Carossino...
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09:42
Development of a deep-red fluorescent glucose-conjugated bioprobe for tumor targeting in vivo
Development of a deep-red fluorescent glucose-conjugated bioprobe for tumor targeting in vivo: Chem. Commun., 2019, Accepted ManuscriptDOI: 10.1039/C9CC07363A, CommunicationYinwei Cheng, Ghulam Shabir, Xiang Li, Laiping Fang, Liyan Xu, Hefeng Zhang, Enmin LiA C1-type D-glucose-conjugated fluorescent probe Glu-1-O-DCSN was synthesized and showed deep-red emission at 685 nm with a Stokes shift of up to 150 nm in DMSO. In in vitro live...The content of this RSS Feed (c) The Royal Society of Chemistry
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09:41
Piezoelectric implant surgery and immediate loading in the aesthetic zone.
Piezoelectric implant surgery and immediate loading in the aesthetic zone.: Related ArticlesPiezoelectric implant surgery and immediate loading in the aesthetic zone.Minerva Stomatol. 2019 Oct;68(5):217-225Authors: Baldi D, Colombo J, Schierano G, Carossa S, Rebaudi A, Pesce P, Pera PAbstract BACKGROUND: Replacement of missing teeth in the anterior aesthetic zone has challenged clinicians with fixed, removable or implant prosthodontics. Problems have been encountered could void aesthetic...
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09:40
Fresh-frozen homologous bone in sinus lifting: histological and radiological analysis.
Fresh-frozen homologous bone in sinus lifting: histological and radiological analysis.: Related ArticlesFresh-frozen homologous bone in sinus lifting: histological and radiological analysis.Minerva Stomatol. 2019 Oct;68(5):226-235Authors: Albanese M, Zotti F, Lanaro L, Trojan D, Paolin A, Montagner G, Iannielli A, Rodella LF, Nocini PFAbstract BACKGROUND: The aim of this study was to evaluate radiological and histological characteristics of fresh-frozen homologous bone as grafting material...
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09:40
Odontogenic phlegmons and abscesses in relation to the financial situation
Odontogenic phlegmons and abscesses in relation to the financial situation of Italian families.: Related ArticlesOdontogenic phlegmons and abscesses in relation to the financial situation of Italian families.Minerva Stomatol. 2019 Oct;68(5):236-241Authors: Fusconi M, Greco A, Galli M, Polimeni A, Yusef M, Di Cianni S, De Soccio G, Federici Stanganelli FR, Lombardi R, de Vincentiis MAbstract BACKGROUND: In recent years, we have recorded an increase in the number of hospital admissions due...
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09:40
Encapsulation of cinnamon oil in whey protein counteracts the disturbances in biochemical parameters, gene expression, and histological picture of the liver and pancreas of diabetic rats
Encapsulation of cinnamon oil in whey protein counteracts the disturbances in biochemical parameters, gene expression, and histological picture of the liver and pancreas of diabetic rats: AbstractThis study aimed to evaluate the protective role of encapsulated cinnamon oil emulsion (COE) in whey protein concentrate (WPC) against the disturbance in lipid profile, oxidative stress markers, and gene expression in streptozotocin (STZ)-treated rats. COE was analyzed using GC-MS, and the emulsion was prepared...
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09:39
Intestinal Alkaline Phosphatase Deficiency Is Associated with Ischemic Heart Disease
Intestinal Alkaline Phosphatase Deficiency Is Associated with Ischemic Heart Disease: Background. We have previously shown that the deficiency of the gut enzyme intestinal alkaline phosphatase (IAP) is associated with type 2 diabetes mellitus (T2DM) in humans, and mice deficient in IAP develop the metabolic syndrome, a precipitant of T2DM and ischemic heart disease (IHD). We hypothesized that IAP deficiency might also be associated with IHD in humans. We aimed to determine the correlation between...
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09:38
High Mib-1-score correlates with new cranial nerve deficits after surgery for frontal skull base meningioma
High Mib-1-score correlates with new cranial nerve deficits after surgery for frontal skull base meningioma: AbstractPostoperative new cranial nerve deficits comprise severe concomitant morbidity in skull base meningioma surgery. Therefore, long-term cranial nerve integrity represents an important outcome measure. In the current study, we analyzed our institutional database in order to identify risk factors for postoperative new cranial nerve morbidity in the course of frontobasal meningioma surgery....
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09:38
Bidirectional Associations among Nicotine and Tobacco Smoke, NeuroHIV, and Antiretroviral Therapy
Bidirectional Associations among Nicotine and Tobacco Smoke, NeuroHIV, and Antiretroviral Therapy: AbstractPeople living with HIV (PLWH) in the antiretroviral therapy (ART) era may lose more life-years to tobacco use than to HIV. Yet, smoking rates are more than twice as high among PLWH than the general population, contributing not just to mortality but to other adverse health outcomes, including neurocognitive deficits (neuroHIV). There is growing evidence that synergy with chronic inflammation...
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09:38
Relapses after using Carnoy's solution in treating aggressive benign odontogenic lesions..............................Carnoy's solution is a fixative composed of 60% ethanol, 30% chloroform and 10% glacial acetic acid,1gm of ferric chloride. Carnoy's solution is a fixation composed of ethanol and glacial acetic acid.Methanol refer of harrison and robbins Wikipedia
Relapses after using Carnoy's solution in treating aggressive benign odontogenic lesions.: Related ArticlesRelapses after using Carnoy's solution in treating aggressive benign odontogenic lesions.Minerva Stomatol. 2019 Oct;68(5):242-248Authors: Costa DC, de O Silveira L, Queiroz SI, Dantas WR, Da Silva JS, Germano ARAbstract BACKGROUND: Chemical curettage has become popular in the definitive treatment of benign aggressive odontogenic lesions. Therefore, this study aims to verify the relapse...
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09:31
Rehabilitation of anterior maxilla with a novel hyperbolic profile transmucosal implant in elderly patients.
Rehabilitation of anterior maxilla with a novel hyperbolic profile transmucosal implant in elderly patients.: Related ArticlesRehabilitation of anterior maxilla with a novel hyperbolic profile transmucosal implant in elderly patients.Minerva Stomatol. 2019 Oct;68(5):249-258Authors: Zamparini F, Pirani C, Chavarria-Bolanos D, Gandolfi MG, Prati CAbstract BACKGROUND: This study aims to evaluate soft and hard tissues response of a two-piece implant placed nonsubmerged in elderly patients'...
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09:26
Effect of metal primers on the bond strength of resin cement to Co-Cr alloy.
Effect of metal primers on the bond strength of resin cement to Co-Cr alloy.: Related ArticlesEffect of metal primers on the bond strength of resin cement to Co-Cr alloy.Minerva Stomatol. 2019 Oct;68(5):259-264Authors: Aranda Garcia de Souza EH, Berger SB, Carlesse Paloco EA, Caixeta RV, Moretto TS, Lopes MB, Gonini A, Guiraldo RDAbstract BACKGROUND: To evaluate the effects of adhesive systems and primer systems on microshear bond strength of chemically activated resin cemented to Co-Cr...
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09:26
Photoelastic analysis of tension distribution in different orthodontic approaches for closing anterior open bites.
Photoelastic analysis of tension distribution in different orthodontic approaches for closing anterior open bites.: Related ArticlesPhotoelastic analysis of tension distribution in different orthodontic approaches for closing anterior open bites.Minerva Stomatol. 2019 Oct;68(5):265-272Authors: Meros GC, Gonini AJ, Lopes MB, Paranhos LR, Suzuki SS, Garcez ASAbstract BACKGROUND: This study aims to evaluate tension distribution in the anterior region of the mandible during two orthodontic...
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09:25
Mannan-Binding Lectin Regulates Inflammatory Cytokine Production, Proliferation, and Cytotoxicity of Human Peripheral Natural Killer Cells
Mannan-Binding Lectin Regulates Inflammatory Cytokine Production, Proliferation, and Cytotoxicity of Human Peripheral Natural Killer Cells: Natural killer (NK) cells represent the founding members of innate lymphoid cells (ILC) and play critical roles in inflammation and the immune response. NK cell effector functions are regulated and fine-tuned by various immune modulators. Mannan (or mannose)-binding lectin (MBL), a soluble C-type lectin, is traditionally recognized as an initiator of the complement...
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09:18
Microcephaly with a simplified gyral pattern in a child with a de novo TUBA1A variant
Microcephaly with a simplified gyral pattern in a child with a de novo TUBA1A variant:
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09:15
Catel–Manzke syndrome without Manzke dysostosis
Catel–Manzke syndrome without Manzke dysostosis: AbstractCatel–Manzke syndrome is characterized by hand anomalies, Robin sequence, cardiac defects, joint hyperextensibility, and characteristic facial features. Approximately 40 patients with Catel–Manzke have been reported, all with the pathognomonic bilateral or unilateral hyperphalangy caused by an accessory bone between the second metacarpal and proximal phalanx known as Manzke dysostosis. Here we present the first case of molecularly confirmed...
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09:14
Peptides, Antibodies, Peptide Antibodies and More
IJMS, Vol. 20, Pages 6289: Peptides, Antibodies, Peptide Antibodies and More: IJMS, Vol. 20, Pages 6289: Peptides, Antibodies, Peptide Antibodies and MoreInternational Journal of Molecular Sciences doi: 10.3390/ijms20246289Authors: Nicole Trier Paul Hansen Gunnar Houen The applications of peptides and antibodies to multiple targets have emerged as powerful tools in research, diagnostics, vaccine development, and therapeutics. Antibodies are unique since they, in theory, can be directed...
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09:14
Neuromuscular Diseases and Bone.
Neuromuscular Diseases and Bone.: Related ArticlesNeuromuscular Diseases and Bone.Front Endocrinol (Lausanne). 2019;10:794Authors: Iolascon G, Paoletta M, Liguori S, Curci C, Moretti AAbstract Neuromuscular diseases (NMDs) are inherited or acquired conditions affecting skeletal muscles, motor nerves, or neuromuscular junctions. Most of them are characterized by a progressive damage of muscle fibers with reduced muscle strength, disability, and poor health-related quality of life of affected...
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09:13
Choice of Aspiration Prevention Surgery for Patients With Neuromuscular Disorders: Report of Three Cases.
Choice of Aspiration Prevention Surgery for Patients With Neuromuscular Disorders: Report of Three Cases.: Related ArticlesChoice of Aspiration Prevention Surgery for Patients With Neuromuscular Disorders: Report of Three Cases.Front Surg. 2019;6:66Authors: Katoh M, Ueha R, Sato T, Sugasawa S, Goto T, Yamauchi A, Yamasoba TAbstract Dysphagia, one of the major complications of neuromuscular diseases such as Parkinson's disease and amyotrophic lateral sclerosis (ALS), decreases quality of...
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09:13
Prognostic factors and risk factors for development and recurrence of sinonasal papillomas: potential role of different HPV subtypes
Prognostic factors and risk factors for development and recurrence of sinonasal papillomas: potential role of different HPV subtypes: AbstractPurpose and methodsA retrospective study was conducted to identify and assess potential clinical and molecularbiological risk factors for development and recurrence of sinonasal papillomas (i.e. inverted (IP), fungiform (FP), and oncocytic papillomas (OCP)). Investigated risk factors included age, gender, tumor size and localization, tobacco smoking, regular...
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09:11
Eight weeks of resistance training increases strength, muscle cross-sectional area and motor unit size, but does not alter firing rates in the vastus lateralis
Eight weeks of resistance training increases strength, muscle cross-sectional area and motor unit size, but does not alter firing rates in the vastus lateralis: AbstractPurposePrevious investigations analyzing resistance training's influence on motor unit (MU) firing rates have yielded mixed results. These mixed results may be clarified by concurrently measuring changes in MU size. Thus, this study analyzed whether post-training strength gains were due to increases in MU firing rates and/or sizes...
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09:09
Antibiotic prophylaxis prescribing habits in oral implant surgery
Antibiotic prophylaxis prescribing habits in oral implant surgery in the Netherlands: a cross-sectional survey: AbstractBackgroundThere seems to be no consensus on the prescription of prophylactic antibiotics in oral implant surgery. The Dutch Association of Oral Implantology (NVOI) guidelines do not include a clear policy on prophylactic antibiotic prescriptions for oral implant surgery among healthy patients. The purpose of the study was to determine whether antibiotic prophylaxis is commonly prescribed...
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09:07
Prevalence and policy of occupational violence against oral healthcare workers: systematic review and meta-analysis
Prevalence and policy of occupational violence against oral healthcare workers: systematic review and meta-analysis: AbstractBackgroundOccupational violence is considered unlawful in professional environments worldwide. In the healthcare industry, including dentistry, the safety of workers is essential, and it is of the utmost importance to ensure patient and employee safety and provide quality care. This study aimed to evaluate the prevalence of violence and associated workplace policies among oral...
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09:06
The brain-harming pesticide chlorpyrifos. Two more chlorpyrifos bans on the books!
Two more chlorpyrifos bans on the books!: This year has been marked by encouraging and long overdue progress toward eradicating the brain-harming pesticide chlorpyrifos. Following on the heels of Hawaii's ban of the chemical last year, California will phase out chlorpyrifos starting early 2020. And as 2019 comes to a close, we can add two more huge victories to the list.Last week, representatives from the European Member States Committee on Plants, Animals, Food and Feed voted to ban the...
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09:05
Global groundswell for agroecology
Global groundswell for agroecology: On a cool October evening, as PAN friends gathered in Northern California to celebrate our 35th Anniversary, I left for Rome, where I joined hundreds of civil society movement leaders from around the world in making the case for agroecology as the most promising way to nourish people and planet.The next morning, walking down ancient Roman streets towards the United Nations Food and Agriculture Organization (FAO), I recalled making the same journey 23 years...
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09:04
Implant survival or implant success? Evaluation of implant-based prosthetic rehabilitation in head and neck cancer patients—a prospective observational study
Implant survival or implant success? Evaluation of implant-based prosthetic rehabilitation in head and neck cancer patients—a prospective observational study: AbstractObjectivesDefinition of implant success is unclear in prosthetic implant-based rehabilitation of head neck cancer patients.Materials and methodsFifty-two patients with 309 inserted implants were included in this prospective observational study. Implant survival (in situ and loaded) and implant success (modified Albrektsson criteria)...
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09:02
Novel biomarkers for risk stratification of Barrett's oesophagus associated neoplastic progression–epithelial HMGB1 expression and stromal lymphocytic phenotype
Novel biomarkers for risk stratification of Barrett's oesophagus associated neoplastic progression–epithelial HMGB1 expression and stromal lymphocytic phenotype: British Journal of Cancer, Published online: 13 December 2019; doi:10.1038/s41416-019-0685-1Novel biomarkers for risk stratification of Barrett's oesophagus associated neoplastic progression–epithelial HMGB1 expression and stromal lymphocytic phenotype AbstractBackgroundThe incidence of oesophageal adenocarcinoma is increasing globally....
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09:00
Principles and mechanisms of non-genetic resistance in cancer
Principles and mechanisms of non-genetic resistance in cancer: British Journal of Cancer, Published online: 13 December 2019; doi:10.1038/s41416-019-0648-6Principles and mechanisms of non-genetic resistance in cancer As well as undergoing genetic evolution, cancer cells can alter their epigenetic state to adapt and resist treatment. This non-genetic evolution is emerging as a major component of cancer resistance. Only now are we beginning to acquire the necessary data and tools to establish...
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08:59
Effects of stress on functional connectivity during verbal processing
Effects of stress on functional connectivity during verbal processing: AbstractEffects of stress on functional connectivity (FC) in specific language processing regions of the brain during verbal fluency tasks were explored. Roles of gender and serotonin transporter gene polymorphisms (5-HTTLPR), associated with stress susceptibility, were also examined to understand their effect. Forty-five healthy volunteers (Mean age: 19.6 ± 1.6 years; 28 females) participated. Functional magnetic resonance imaging...
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08:58
Resting-state causal connectivity of the bed nucleus of the stria terminalis in panic disorder
Resting-state causal connectivity of the bed nucleus of the stria terminalis in panic disorder: AbstractPanic disorder (PD) is associated with anticipatory anxiety, a sustained threat response that appears to be related to the bed nucleus of the stria terminalis (BNST). Individuals with panic disorder may demonstrate significant differences in causal connectivity of the BNST in comparison to healthy controls. To test this hypothesis, resting-state functional magnetic resonance imaging (fMRI) was...
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08:56
Circulating tumor DNA (ctDNA) in precision oncology of ovarian cancer
Circulating tumor DNA (ctDNA) in precision oncology of ovarian cancer: Pharmacogenomics, Volume 20, Issue 18, Page 1251-1253, December 2019.
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08:56
Spleen Organoid Units Generate Functional Human and Mouse Tissue-Engineered Spleen in a Murine Model
Spleen Organoid Units Generate Functional Human and Mouse Tissue-Engineered Spleen in a Murine Model: Tissue Engineering Part A, Ahead of Print. AbstractIntroduction: Splenectomy is common after trauma or hematologic disease, and alters immune protection against pathogens, which may lead to fulminant infection with high mortality. Yet the spleen has demonstrable regenerative capacity and cells might be recovered and reimplanted at the time of injury or excision to avoid these risks.Methods: Tissue-engineered...
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08:55
Sorafenib may enhance antitumour efficacy in hepatocellular carcinoma patients by modulating the proportions and functions of natural killer cells
Sorafenib may enhance antitumour efficacy in hepatocellular carcinoma patients by modulating the proportions and functions of natural killer cells: SummaryDysfunction of natural killer (NK) cells is associated with poor prognosis in hepatocellular carcinoma (HCC). We explored the phenotypic and functional characteristics of peripheral blood NK cells in HCC patients following sorafenib treatment.Peripheral blood samples were collected from 60 HCC patients in a single centre (2015~2017) and 45 healthy...
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08:54
Bioprinting in 2019
The Year in Review: Bioprinting in 2019: This year, the bioprinting community has discovered ways to speed up precision in 3D bioprinting. Even though experts have warned us that 3D printed organs might not be available for a long time, we can't help the excitement after witnessing crucial progress in 2019 that gets us closer to the possibility of having functional, compatible and working organs and tissues, especially after researchers made significant progress with different tissues and structures....
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08:54
Victim of E. coli O157:H7 outbreak sues ALDI in federal court over poison romaine
Victim of E. coli O157:H7 outbreak sues ALDI in federal court over poison romaine: UPDATE— A common grower with multiple romaine fields in California's Salinas growing region is likely responsible for all three current  E. coli O157: H7 outbreaks.   That was the word in a late Thursday update from the Food and Drug Administration (FDA).  FDA, the Centers for Disease Control and Prevention (CDC) and California state government are deploying a team to conduct a new investigation of the yet un-named...
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08:52
Foodborne outbreak illnesses
EU notes rise in foodborne outbreak illnesses and deaths in 2018: The number of people getting sick, being hospitalized and dying in foodborne outbreaks in Europe increased in 2018, according to the annual report on zoonoses.Salmonella caused almost one in three outbreaks last year with Salmonella Enteritidis behind one in five. Salmonella in egg products was the highest risk agent and food pair based on data published by the European Food Safety Authority (EFSA) and the European Centre for Disease...
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08:52
Evaluation of a modified vancomycin nomogram for obese adults
Evaluation of a modified vancomycin nomogram for obese adults: AbstractPurposeThe purpose of this study was to compare therapeutic vancomycin trough levels in obese adults when using an original nomogram (phase I) versus a modified nomogram (phase II).MethodsThis study compared a vancomycin nomogram with a modified vancomycin nomogram for obese adults over 100 kg. The primary endpoint compared the percentage of sub-therapeutic, therapeutic, and supra-therapeutic vancomycin trough concentrations between...
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08:51
Readmission rates and associated factors following rib cage injury
Readmission rates and associated factors following rib cage injury: BACKGROUND There remains a lack of knowledge about readmission characteristics after sustaining rib fractures. We aimed to determine rates, characteristics, and predictive/protective factors associated with unexpected reevaluation and readmission after rib cage injury. METHODS A retrospective review was performed based on trauma patients evaluated at an urban Level I trauma center from January 2014 to December 2016. Adult...
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08:51
Selective nonoperative management of renal gunshot wounds
Selective nonoperative management of renal gunshot wounds: BACKGROUND Selective nonoperative management (SNOM) of blunt kidney injuries has been the standard of care for decades. However, the role of SNOM after renal gunshot wounds (GSWs) remains unclear. The purpose of this study was to assess the safety and outcomes of SNOM of renal GSWs at a national level.METHODS The National Trauma Data Bank was queried for patients who sustained a GSW to the kidney (January 2007 to December 2014). Patients...
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08:50
Splenic findings in patients with acute babesiosis
Splenic findings in patients with acute babesiosis: AbstractPurposeTo identify the imaging manifestations of splenic involvement in babesiosis, a potentially fatal tick-borne zoonosis with multi-organ involvement.MethodsIn our single center HIPAA compliant IRB-approved study, we performed a retrospective search of the electronic medical record at our institution to identify all patients with known or suspected acute babesiosis from 2000 to 2017. We then reviewed all abdominal imaging of patients...
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08:49
Mandibular angle fractures: Does presence of third molars in fracture line affect postoperative complications?
Mandibular angle fractures: Does presence of third molars in fracture line affect postoperative complications?: This review of whether the presence of the lower third molar in the mandibular angle fracture line is associated with postoperative complications included 34 studies. The quality of teh included studies was low to very low so the findings should be viewed cautiously. The post Mandibular angle fractures: Does presence of third molars in fracture line affect postoperative complications? appeared...
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08:49
A personalized computational model predicts cancer risk level of oral potentially malignant disorders and its web application for promotion of non-invasive screening.
A personalized computational model predicts cancer risk level of oral potentially malignant disorders and its web application for promotion of non-invasive screening.: Related ArticlesA personalized computational model predicts cancer risk level of oral potentially malignant disorders and its web application for promotion of non-invasive screening.J Oral Pathol Med. 2019 Dec 10;:Authors: Wang X, Yang J, Wei C, Zhou G, Wu L, Gao Q, He X, Shi J, Mei Y, Liu Y, Shi X, Wu F, Luo J, Guo Y, Zhou Q, Yin...
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08:48
New Plasmonic Biosensors for Determination of Human Hemoglobin Concentration in Blood
New Plasmonic Biosensors for Determination of Human Hemoglobin Concentration in Blood: AbstractTwo new types of plasmonic biosensors are applied for detection of hemoglobin concentration in human blood by using the angular interrogation method. The first type of the fiber with five layers is made by a SiO2 core surrounded by GaP, gold, Al2O3 and hemoglobin layers. The second type of the fiber with six layers is made by a ZBLAN core surrounded by NaF, silicon, silver, Al2O3 and hemoglobin layers....
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08:48
Machine Learning and Cochlear Implantation—A Structured Review of Opportunities and Challenges
Machine Learning and Cochlear Implantation—A Structured Review of Opportunities and Challenges: Conclusion: The relationship between CI and artificial intelligence is strengthening with a recent increase in publications reporting successful applications. Considerable effort has been directed toward augmenting signal processing and automating postoperative MAPping using machine learning algorithms. Other promising applications include augmenting CI surgery mechanics and personalized medicine approaches...
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08:47
Surgical management of non melanoma skin cancer of the head and neck.
Surgical management of non melanoma skin cancer of the head and neck.: Related ArticlesSurgical management of non melanoma skin cancer of the head and neck.Oral Oncol. 2019 Dec 07;100:104485Authors: Kansara S, Bell D, Weber RAbstract Non-melanoma skin cancer (NMSC) is the most common malignancy in the world and is reaching epidemic proportions. The most common types of NMSC include basal cell carcinoma (BCC) and squamous cell carcinoma (SCC). The head and neck is the most common site for...
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08:46
Relationship between inflammation and the severity of Recurrent Respiratory Papillomatosis
Relationship between inflammation and the severity of Recurrent Respiratory Papillomatosis: Publication date: Available online 18 November 2019Source: American Journal of OtolaryngologyAuthor(s): Vivian Narana Ribeiro El Achkar, Andressa Duarte, Román Carlos, Jorge Esquiche León, Alfredo Ribeiro-Silva, Shirley Shizue Nagata Pignatari, Estela KaminagakuraAbstractObjectiveTo characterize inflammatory cells in Recurrent Respiratory Papillomatosis (RRP) and to correlate it with severity using the Derkay...
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08:45
Endolymphatic hydrops evaluation on MRI: Practical considerations
Endolymphatic hydrops evaluation on MRI: Practical considerations: Publication date: Available online 23 November 2019Source: American Journal of OtolaryngologyAuthor(s): Rafael Maffei Loureiro, Daniel Vaccaro Sumi, Hugo Luis de Vasconcelos Chambi Tames, Carolina Ribeiro Soares, Marcio Cavalcante Salmito, Regina Lucia Elia Gomes, Mauro Miguel DanielAbstractFour-hour delayed three-dimensional fluid-attenuated inversion recovery (3D-FLAIR) sequence after intravenous gadolinium-based contrast agent...
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08:45
The anesthesia airway evaluation: Correlation with sleep endoscopy findings
The anesthesia airway evaluation: Correlation with sleep endoscopy findings: Publication date: Available online 23 November 2019Source: American Journal of OtolaryngologyAuthor(s): Michael Eggerstedt, Matthew J. Urban, Emily Chi, Ethan M. Ritz, Phillip LosavioAbstractPurposeDrug-induced sleep endoscopy (DISE) is a cost-effective, safe, and reliable tool to evaluate obstructive sleep apnea (OSA) patients by revealing upper airway sites, patterns, and severity of obstruction. DISE provides valuable...
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08:44
Efficacy of the additional effect of hyperbaric oxygen therapy in combination of systemic steroid and prostaglandin E1 for idiopathic sudden sensorineural hearing loss
Efficacy of the additional effect of hyperbaric oxygen therapy in combination of systemic steroid and prostaglandin E<sub>1</sub> for idiopathic sudden sensorineural hearing loss: Publication date: Available online 27 November 2019Source: American Journal of OtolaryngologyAuthor(s): Satoshi Hara, Takeshi Kusunoki, Hirotomo Honma, Yoshinobu Kidokoro, Katsuhisa IkedaAbstractPurposeThe efficacies of hyperbaric oxygen therapy (HBO), systemic steroid, prostaglandin E1, or the combination of...
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08:38
Oncological outcomes of early stage glottic squamous cell carcinoma treated with transoral laser microsurgery
Oncological outcomes of early stage glottic squamous cell carcinoma treated with transoral laser microsurgery: Publication date: Available online 28 November 2019Source: American Journal of OtolaryngologyAuthor(s): Lei Lei, Daling Zhong, Jian Zou, Haiyang Wang, Hui Yang, Yu Zhao, Jun Liu, Danni Cheng, Fumei WuAbstractMaterials and methodsThe records of patients treated with TLM with previously untreated early stage glottic squamous cell carcinoma were reviewed.ResultsA total of 201 patients were...
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08:37
Relationship between progression of type 2 diabetes mellitus and olfactory function
Relationship between progression of type 2 diabetes mellitus and olfactory function: Publication date: Available online 29 November 2019Source: American Journal of OtolaryngologyAuthor(s): Kerem Sami Kaya, Emrah Erkan Mazı, Semra Tiryaki Demir, Fatih Tetik, Müjgan Tuna, Suat TurgutAbstractObjectivesIn the literature, diabetes mellitus was mentioned as one of the etiologic factors of olfactory disorder. However, association between olfactory dysfunction and complications of type 2 diabetes mellitus...
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08:37
Objective and subjective changes in voice after endoscopic sinus surgeries in patients with and without nasal polyps
Objective and subjective changes in voice after endoscopic sinus surgeries in patients with and without nasal polyps: Publication date: Available online 5 December 2019Source: American Journal of OtolaryngologyAuthor(s): Eugene Hung Chih Wong, Aun Wee ChongAbstractBackgroundMany studies have looked at the effect of functional endoscopic sinus surgeries (FESS) on nasalance, nasal consonant and nasalized vowels. Only two studies investigated the effect of FESS on vocal sound quality and have not found...
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08:37
Retrospective study of Langerhans cell histiocytosis in ear, nose and neck
Retrospective study of Langerhans cell histiocytosis in ear, nose and neck: Publication date: Available online 6 December 2019Source: American Journal of OtolaryngologyAuthor(s): Yan Guo, Fei Ning, Guojian Wang, Xiaohong Li, Jisheng Liu, Yongyi Yuan, Pu DaiAbstractObjectiveLangerhans cell histiocytosis (LCH) is a rare clinical disorder. We retrospectively analysed the clinical manifestations, treatments and prognoses of LCH cases involving the ear, nose, and neck.Materials and methods28 cases with...
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08:37
Early discharge after free-tissue transfer does not increase adverse events
Early discharge after free-tissue transfer does not increase adverse events: Publication date: Available online 10 December 2019Source: American Journal of OtolaryngologyAuthor(s): Andrea Hanick, Joseph B. Meleca, Michael A. FritzAbstractIntroductionDemonstrate that carefully selected free flap patients may be discharged early after surgery without increasing the rates of postoperative complications or readmissions.MethodsBased on a published article in Laryngoscope 2016 of 51 free-tissue transfers,...
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08:36
Short-term postoperative CPAP may improve the outcomes of velopharyngeal surgery for obstructive sleep apnea
Short-term postoperative CPAP may improve the outcomes of velopharyngeal surgery for obstructive sleep apnea: Publication date: Available online 11 December 2019Source: American Journal of OtolaryngologyAuthor(s): Guoping Yin, Mu He, Jinkun Xu, Xin Cao, Yuhuan Zhang, Jingying YeAbstractPurposeTo evaluate the effects of short-term postoperative continuous positive airway pressure (CPAP) on the outcomes of velopharyngeal surgery for obstructive sleep apnea (OSA).Materials and methodsThis study included...
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08:36
Role of erector spinae plane block versus paravertebral block in pain control after modified radical mastectomy. A prospective randomised trial
Role of erector spinae plane block versus paravertebral block in pain control after modified radical mastectomy. A prospective randomised trial: Mona Raafat El Ghamry, Asmaa Fawzy AmerIndian Journal of Anaesthesia 2019 63(12):1008-1014Background and Aims: Thoracic paravertebral block (TPVB) provides effective analgesia in breast surgery. Recently, use of erector spinae plane block (ESPB) in controlling post-operative pain has proved effective. This study aimed to compare the effect of ESPB with TPVB...
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08:00
Airway management in prone position following penetrating iron rod injury in back: An anaesthetic challenge
Airway management in prone position following penetrating iron rod injury in back: An anaesthetic challenge: Ashwani Sharma, Lalit Gupta, Bhavna GuptaIndian Journal of Anaesthesia 2019 63(12):1039-1040A 20-year-old male was impaled by the iron rod piercing the gluteal region and coming out diagonally when he fell from height while working at an under-construction two-storey building [Figure 1]. In view of suspected spinal injury, the patient was transferred on a 'spine board' in the prone position....
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08:00
Levosimendan for patients with heart failure undergoing major oncological surgery: A randomised blinded pilot study
Levosimendan for patients with heart failure undergoing major oncological surgery: A randomised blinded pilot study: Ehab H Shaker, Khaled Hussein, Ehab M ReyadIndian Journal of Anaesthesia 2019 63(12):1001-1007Background and Aims: Cardiovascular diseases and cancer are among the leading causes of mortality worldwide. The aim of this study is to evaluate the efficacy and safety of preoperative administration of levosimendan in patients with chronic heart failure (CHF) scheduled for major abdominal...
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07:59
Craniotomy in Klippel-Trenaunay syndrome: Concerns and challenges
Craniotomy in Klippel-Trenaunay syndrome: Concerns and challenges: RP Sangeetha, Nisha Baskar, Sriganesh Kamath, Priyadharshi DixitIndian Journal of Anaesthesia 2019 63(12):1033-1035Klippel-Trenaunay syndrome (KTS) is a rare congenital disorder characterised by cutaneous capillary malformations, soft tissue and bone hypertrophy and venous varicosities. The coexistence of Chiari 1 malformation and an intracranial tumour has been rarely reported in the literature. Multisystem involvement of this syndrome...
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07:58
Comparison of norepinephrine and phenylephrine boluses for the treatment of hypotension during spinal anaesthesia for caesarean section – A randomised controlled trial
Comparison of norepinephrine and phenylephrine boluses for the treatment of hypotension during spinal anaesthesia for caesarean section – A randomised controlled trial: Nitu Puthenveettil, Swetha N Sivachalam, Sunil Rajan, Jerry Paul, Lakshmi KumarIndian Journal of Anaesthesia 2019 63(12):995-1000Background and Aims: Hypotension following spinal anaesthesia for caesarean section is common in spite of adequate fluid loading. Phenylephrine is the recommended drug to treat spinal hypotension during...
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07:58
Comparison of success rate of BlockBuster® versus Fastrach® LMA as conduit for blind endotracheal intubation: A prospective randomised trial
Comparison of success rate of BlockBuster® versus Fastrach® LMA as conduit for blind endotracheal intubation: A prospective randomised trial: Archana Endigeri, Anilkumar Ganeshnavar, B V S Varaprasad, YH Shivanand, Basavaraja AyyangoudaIndian Journal of Anaesthesia 2019 63(12):988-994Background and Aims: BlockBuster® Laryngeal Mask Airway, a newer supraglottic airway device, is claimed to be an efficient conduit for endotracheal intubation. Intubating laryngeal mask airway (LMA) is an established...
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07:57
Society of Onco-Anaesthesia and Perioperative Care consensus guidelines for perioperative management of patients for cytoreductive surgery and hyperthermic intraperitoneal chemotherapy (CRS-HIPEC)
Society of Onco-Anaesthesia and Perioperative Care consensus guidelines for perioperative management of patients for cytoreductive surgery and hyperthermic intraperitoneal chemotherapy (CRS-HIPEC): Sohan Lal Solanki, Sudipta Mukherjee, Vandana Agarwal, Raghu S Thota, Kalpana Balakrishnan, Shagun Bhatia Shah, Neha Desai, Rakesh Garg, Reshma P Ambulkar, Nitin Madhukar Bhorkar, Viplab Patro, Snita Sinukumar, Meenakshi V Venketeswaran, Malini P Joshi, Rajesh Holalu Chikkalingegowda, Vijaya Gottumukkala,...
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07:57
The path to safe and accessible anaesthesia care
The path to safe and accessible anaesthesia care: Tyler J Law, Michael Lipnick, Muralidhar Joshi, Girija P Rath, Adrian W GelbIndian Journal of Anaesthesia 2019 63(12):965-971The increasing focus on and importance of surgical care in achieving universal health coverage requires the development of safe and accessible anaesthesia services. Increasing access to care by supporting the necessary inputs to the anaesthesia system, including medications, equipment and personnel, must be accompanied by processes...
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07:56
Spontaneous ventilation as a key ventilation technique during open airway phase in tracheal resection and reconstruction: A case series
Spontaneous ventilation as a key ventilation technique during open airway phase in tracheal resection and reconstruction: A case series: Ranjith K Sivakumar, Sakthirajan Panneerselvam, Duraiyarassu Uthaman, Priya Rudingwa, Ramya RaviIndian Journal of Anaesthesia 2019 63(12):1029-1032Anaesthetic management of tracheal resection and reconstruction in patients with difficult tracheal pathologies, poses unique challenges—such as pre-operative assessment and preparation, the induction of general anaesthesia,...
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07:56
Prone ventilation in H1N1 virus-associated severe acute respiratory distress syndrome: A case series
Prone ventilation in H1N1 virus-associated severe acute respiratory distress syndrome: A case series: Jyoti Narayan Sahoo, Mohan Gurjar, Krantimaya Mohanty, Kalpana Majhi, G SradhanjaliInternational Journal of Critical Illness and Injury Science 2019 9(4):182-186Background: Management of H1N1 viral infection-associated acute respiratory distress syndrome (ARDS) has primarily been focused on lung protective ventilation strategies, despite that mortality remains high (up to 45%). Other measures to...
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07:55
A rare case of hypokalemic ventricular tachycardia in a patient with thyrotoxic periodic paralysis
A rare case of hypokalemic ventricular tachycardia in a patient with thyrotoxic periodic paralysis: Bader Abu Ghalyoun, Ibrahim Khaddash, Dema Shamoon, Hamid Shaaban, Michael Hanna, Satish Tiyyagura, Mourad IsmailInternational Journal of Critical Illness and Injury Science 2019 9(4):199-202Thyrotoxic periodic paralysis (TPP) is a potentially fatal complication of hyperthyroidism, characterized by recurrent muscle paralysis and hypokalemia. We present a case of a 32-year-old apparently healthy male...
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07:54
Role of central venous oxygen saturation in prognostication of patients with severe sepsis and septic shock in emergency medical services
Role of central venous oxygen saturation in prognostication of patients with severe sepsis and septic shock in emergency medical services: Susheel Kumar, Gauri Jangpangi, Ashish Bhalla, Navneet SharmaInternational Journal of Critical Illness and Injury Science 2019 9(4):164-171Introduction: All the components of early goal-directed therapy, especially central venous oxygen saturation (ScvO2) as one of the endpoints of resuscitation, may not have mortality benefit, more so after results of the Australasian...
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07:53
Scrub typhus – A case series from the state of Sikkim, India
Scrub typhus – A case series from the state of Sikkim, India: Aroop Mohanty, Ankita Kabi, Pratima Gupta, Mithilesh Kumar Jha, U Sasi Rekha, Anusha Krishna RajInternational Journal of Critical Illness and Injury Science 2019 9(4):194-198Scrub typhus is one of the leading causes of acute febrile illness in India. It is associated with rash and often an eschar, which responds dramatically to antibiotics. In some cases, it results in serious illness leading to multiple organ involvement and finally death....
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07:53
Clinical evaluation of Ambu® Aura-i™ – A new intubating laryngeal mask airway as an independent ventilatory device and a conduit for tracheal intubation in pediatric patients
Clinical evaluation of Ambu® Aura-i™ – A new intubating laryngeal mask airway as an independent ventilatory device and a conduit for tracheal intubation in pediatric patients: Triveni M Rangaswamy, Avnish Bharadwaj, Priyanka JainInternational Journal of Critical Illness and Injury Science 2019 9(4):157-163Background: Ambu® Aura-i™, a recently introduced second generation supraglottic airway device has been designed to function as an independent ventilatory device as well as a conduit for passage...
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07:52
Swan-Ganz catheter causing anaphylactic shock: A rare case report
Swan-Ganz catheter causing anaphylactic shock: A rare case report: Muhammad Usman Asghar, Sanwal Singh Mehta, Hira Asif Cheema, Krishna KommineniInternational Journal of Critical Illness and Injury Science 2019 9(4):203-205Latex-induced anaphylactic reactions are often underestimated in patients having procedures in a catheterization lab, intensive care units, or in operating rooms. Most physicians are not aware that almost all balloons in the Swan-Ganz catheter (SGC) are made up of latex. Direct...
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07:52
Initial choice of antibiotic in recurrent spontaneous bacterial peritonitis: A retrospective study
Initial choice of antibiotic in recurrent spontaneous bacterial peritonitis: A retrospective study: Gayathri Vasanthakumari Sasidharan Nair, Prannoy George Mathen, M Gopalakrishna Pillai, KP Gireesh Kumar, KK Velayudhan, TP SreekrishnanInternational Journal of Critical Illness and Injury Science 2019 9(4):187-190Context: Spontaneous bacterial peritonitis (SBP) is a commonly encountered infection seen in the setting of ascites secondary to advanced liver disease. Recurrence of SBP is common and is...
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07:52
Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,00306932607174,alsfakia@gmail.com, Telephone consultation 11855 int 1193,
Successful Treatment of Cosmetic Eyebrow Tattoos in Fitzpatrick III‐IV With Picosecond (1,064, 532‐nm) Neodymium‐Doped Yttrium Aluminum Garnet Laser With a Perfluorodecalin‐Infused Patch: A Pilot StudySuccessful Treatment of Cosmetic Eyebrow Tattoos in Fitzpatrick III‐IV With Picosecond (1,064, 532‐nm) Neodymium‐Doped Yttrium Aluminum Garnet Laser With a Perfluorodecalin‐Infused Patch: A Pilot Study: Background and ObjectivesNanosecond Q‐switched lasers have been used for the removal of traditional...
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Thu Dec 12, 2019 11:02
MDPI
 International Journal of Environmental Research and Public HealthIJERPH, Vol. 16, Pages 5065: Vulnerability and Adaptation to Extreme Heat in Odisha, India: A Community Based Comparative StudyIJERPH, Vol. 16, Pages 5065: Vulnerability and Adaptation to Extreme Heat in Odisha, India: A Community Based Comparative Study International Journal of Environmental Research and Public Health doi: 10.3390/ijerph16245065 Authors: Subhashisa Swain Shreeporna Bhattacharya Ambarish Dutta Sanghamitra Pati Lipika...
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Thu Dec 12, 2019 10:56
MDPI
 MicroorganismsMicroorganisms, Vol. 7, Pages 683: Thriving in Wetlands: Ecophysiology of the Spiral-Shaped Methanotroph Methylospira mobilis as Revealed by the Complete Genome SequenceMicroorganisms, Vol. 7, Pages 683: Thriving in Wetlands: Ecophysiology of the Spiral-Shaped Methanotroph Methylospira mobilis as Revealed by the Complete Genome Sequence Microorganisms doi: 10.3390/microorganisms7120683 Authors: Oshkin Miroshnikov Danilova Hakobyan Liesack Dedysh Candidatus Methylospira mobilis is a...
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Thu Dec 12, 2019 10:20
MDPI
 International Journal of Environmental Research and Public HealthIJERPH, Vol. 16, Pages 5040: Critical Appraisal of Qualitative Studies of Muslim Females' Perceptions of Physical Activity Barriers and FacilitatorsIJERPH, Vol. 16, Pages 5040: Critical Appraisal of Qualitative Studies of Muslim Females' Perceptions of Physical Activity Barriers and Facilitators International Journal of Environmental Research and Public Health doi: 10.3390/ijerph16245040 Authors: David Kahan Muslim women's perceptions...
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Thu Dec 12, 2019 10:20
MDPI
Cells, Vol. 8, Pages 1611: Farnesol, a Quorum-Sensing Molecule of Candida Albicans Triggers the Release of Neutrophil Extracellular TrapsCells, Vol. 8, Pages 1611: Farnesol, a Quorum-Sensing Molecule of Candida Albicans Triggers the Release of Neutrophil Extracellular Traps Cells doi: 10.3390/cells8121611 Authors: Zawrotniak Wojtalik Rapala-Kozik The efficient growth of pathogenic bacteria and fungi in the host organism is possible due to the formation of microbial biofilms that cover the host tissues....
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Thu Dec 12, 2019 10:19
MDPI
Antibiotics, Vol. 8, Pages 261: Re-Understanding the Mechanisms of Action of the Anti-Mycobacterial Drug BedaquilineAntibiotics, Vol. 8, Pages 261: Re-Understanding the Mechanisms of Action of the Anti-Mycobacterial Drug Bedaquiline Antibiotics doi: 10.3390/antibiotics8040261 Authors: Jickky Palmae Sarathy Gerhard Gruber Thomas Dick Bedaquiline (BDQ) inhibits ATP generation in Mycobacterium tuberculosis by interfering with the F-ATP synthase activity. Two mechanisms of action of BDQ are broadly accepted....
www Αλέξανδρος Γ. Σφακιανάκης
Thu Dec 12, 2019 10:18
Substernal Mass: A Rare Presentation of Hepatocellular Carcinoma
http://omjournal.org/articleDetails.aspx?coType=1&aId=2510Kevin Yuqi Wang1, Mohammad Ghasemi Rad1*, Camelia Arsene2 and Doina David31Department of Radiology, Baylor College of Medicine, Houston, Texas, USA2Department of Internal Medicine, Wayne State School of Medicine, Michigan, USA3Department of Pathology, Wayne State School of Medicine, Michigan, USAARTICLE INFOArticle history:Received: 22 August 2017Accepted: 3 September 2018Online:DOI 10.5001/omj.2019.101Keywords:Hepatocellular Carcinoma;...
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Thu Dec 12, 2019 10:14
Eosinophilic Fasciitis Responds Well to Steroids and Methotrexate
http://omjournal.org/articleDetails.aspx?coType=1&aId=2511Asmaa Sabr Mahdi1*, Iman H. Nasr2, Suad Al Jahdhami3, Atheel Kamona4 and Humaid A. Al Wahshi11Department of Medicine, Rheumatology Unit, Royal Hospital, Muscat, Oman2Immunology Department, Royal Hospital, Muscat, Oman3Histopathology Department, Sultan Qaboos University Hospital, Muscat, Oman4Radiology Department, Royal Hospital, Muscat, OmanARTICLE INFOArticle history:Received: 20 February 2018Accepted: 4 July 2018Online:DOI 10.5001/omj.2019.102Keywords:Eosinophilic...
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Thu Dec 12, 2019 10:13
Comparative Study of the Therapeutic Potential of Mesenchymal Stem Cells Derived from Adipose Tissue and Bone Marrow on Acute Myocardial Infarction Model
http://omjournal.org/articleDetails.aspx?coType=1&aId=2522Amira M. Omar1*, Anisa E. Meleis1, Samia A. Arfa1, Noha M. Zahran1 and Radwa A. Mehanna2,3*1Histology and Cell Biology Department, Faculty of Medicine, Alexandria University, Alexandria, Egypt2Medical Physiology Department, Faculty of Medicine, Alexandria University, Alexandria, Egypt3Center of Excellence for Research in Regenerative Medicine and Applications, Faculty of Medicine, Alexandria University, Alexandria, EgyptARTICLE INFOArticle...
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Thu Dec 12, 2019 10:12
Adverse Cutaneous Reactions of Common Biologic Medications for Rheumatic Diseases
Adverse Cutaneous Reactions of Common Biologic Medications for Rheumatic Diseases: AbstractPurpose of ReviewWithin the last two decades, the application of biologic medications for rheumatic diseases has greatly expanded. Therefore, it is important for clinicians to be knowledgeable about potential adverse reactions of this medication class. The goal of this review is to discuss the current understanding of cutaneous adverse reactions that may occur with common biologic medications utilized in the...
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Thu Dec 12, 2019 08:46
Cancer and Idiopathic Inflammatory Myositis
Cancer and Idiopathic Inflammatory Myositis: AbstractPurpose of ReviewHere we present an update on best practices and clinical considerations when evaluating IIM patients for malignancy.Recent FindingsIdiopathic inflammatory myopathies (IIM) comprise a group of diseases including dermatomyositis (DM), polymyositis (PM), and immune-mediated necrotizing myopathies (IMNM). There is an increased risk of concomitant cancer near the time of myositis onset (cancer-associated myositis, CAM) in unique subsets...
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Thu Dec 12, 2019 08:44
Cannabis-Based Medicines and Medical Cannabis in Rheumatic Diseases: A Treasure Chest or Pandora's box
Cannabis-Based Medicines and Medical Cannabis in Rheumatic Diseases: A Treasure Chest or Pandora's box: AbstractPurposeInterest in cannabinoids as a therapy in rheumatic diseases has grown exponentially. With legalization of medical and recreational cannabis in many jurisdictions worldwide, patients have easier access and opportunity to explore medicinal use. We report on the evidence for effect of cannabinoids in rheumatic diseases and critically address the current challenges surrounding use.Recent...
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Thu Dec 12, 2019 08:44
Management of Calcinosis Associated with Dermatomyositis
Management of Calcinosis Associated with Dermatomyositis: AbstractPurpose of reviewCalcinosis cutis, or dystrophic soft-tissue calcification, is a common and debilitating complication of adult and juvenile dermatomyositis. Dermatomyositis-associated calcinosis is difficult to treat and is associated with significant morbidity. The purpose of this review is to provide an update of treatment modalities for calcinosis in dermatomyositis based on published studies.Recent findingsSpecific guidelines are...
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Thu Dec 12, 2019 08:43
Interventions on Modifiable Risk Factors for the Development of Psoriatic Arthritis
Interventions on Modifiable Risk Factors for the Development of Psoriatic Arthritis: AbstractPurpose of the reviewPrevention of the development of a disease is one of the most effective and desirable outcomes in medicine. Several modifiable risk factors for the development of psoriatic arthritis (PsA) have been studied. The following review will focus on modifiable risk factors for PsA development and the evidence on interventions that may have the potential to prevent PsA.Recent findingsThe domains...
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Thu Dec 12, 2019 08:43
Gout Management in Chronic Kidney Disease: Pearls and Pitfalls
Gout Management in Chronic Kidney Disease: Pearls and Pitfalls: AbstractPurpose of reviewGout is more prevalent than ever and is associated with multiple chronic comorbidities, including Chronic Kidney Disease (CKD). While goals of treatment are the same as in those without renal impairment, co-morbid CKD poses a challenge in treatment selection and requires a solid understanding of potential drug-drug interaction and drug-related toxicity.Recent findingsIn acute gout complicated by CKD, NSAIDs should...
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Thu Dec 12, 2019 08:42
Short-Scar Augmentation Mastopexy in Massive-Weight Loss Patients: Four-Step Surgical Principles for Reliable and Reproducible Results
Short-Scar Augmentation Mastopexy in Massive-Weight Loss Patients: Four-Step Surgical Principles for Reliable and Reproducible Results: AbstractBackgroundSingle-stage augmentation mastopexy is considered a challenging procedure, and its safety and efficacy remain controversial for breasts with grade-2 and grade-3 ptosis. In this paper, we report our experience in single-stage augmentation mastopexy with implants, using a short-scar technique, outlining the four-step principles of our technique which...
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Thu Dec 12, 2019 08:42
Clinical Features of Skin Infection After Rhinoplasty with Only Absorbable Thread (Polydioxanone) in Oriental Traditional Medicine: A Case Series Study
Clinical Features of Skin Infection After Rhinoplasty with Only Absorbable Thread (Polydioxanone) in Oriental Traditional Medicine: A Case Series Study: AbstractBackgroundPolydioxanone (PDO) is absorbable thread which is usually used for wound closure and face lifting. These days, PDO thread is used increasingly for aesthetic purposes such as correction of facial wrinkles, laxity and even rhinoplasty in many oriental traditional medicine clinics. As rhinoplasty with PDO thread increases, complications...
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Thu Dec 12, 2019 08:42
Autologous Breast Reconstruction with SIEA Flaps: An Alternative in Selected Cases
Autologous Breast Reconstruction with SIEA Flaps: An Alternative in Selected Cases: AbstractBackgroundThe deep inferior epigastric perforator flap has been shown to be a reliable option for autologous breast reconstruction. A further refinement in the transfer of lower abdominal tissue is the superficial inferior epigastric artery (SIEA) flap that does not require any incision of the rectus abdominis fascia or muscle and is superior regarding donor-site morbidity.ObjectivesWe conducted a retrospective...
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Thu Dec 12, 2019 08:41
Anterior Nasal Spine Relocation for Caudal Septal Deviation: A Case Series and Discussion of Common Scenarios
Anterior Nasal Spine Relocation for Caudal Septal Deviation: A Case Series and Discussion of Common Scenarios: AbstractBackgroundDeviation of the anterior nasal spine (ANS) is a common cause of caudal nasal septal deviation. In our experience, relocation of the deviated ANS is a useful technique in the correction of the caudal septal deviation.ObjectivesTo describe our experience with the ANS relocation technique in isolation and in combination with other techniques for correction of caudal septal...
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Thu Dec 12, 2019 08:41
Bleeding in Plastic–Aesthetic Surgery: A Prognostic Pathway with Clinical Application
Bleeding in Plastic–Aesthetic Surgery: A Prognostic Pathway with Clinical Application: AbstractOne of the potential complications of aesthetic surgery is bleeding. Given the high surgical activity carried out in our center and the variety of interventions performed, the risk of bleeding is not negligible: A clinical practice that could reduce this postsurgical complication is necessary. The goal of this article is to value effectiveness of a bleeding score obtained through the evaluation of anamnestic...
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Thu Dec 12, 2019 08:41
Perioral Ruler in Routine Esthetic Surgery: Convenient and Exact
Perioral Ruler in Routine Esthetic Surgery: Convenient and Exact: AbstractLip and perioral surgery, like any other esthetic surgery, requires an exact and convenient measurement tool to ensure reliable and reproducible outcomes. Although three-dimensional measuring equipment has proven its effectiveness in measuring facial parameters over the past two decades, it has some drawbacks, including high cost, long scanning times, and non-portability. Thus, digital photography remains the standard tool...
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Thu Dec 12, 2019 08:40
Vision Loss Associated with Hyaluronic Acid Fillers: A Systematic Review of Literature
Vision Loss Associated with Hyaluronic Acid Fillers: A Systematic Review of Literature: AbstractBackgroundWith the global increase in the use of injectable fillers, more cases with serious adverse events such as skin ischemia and vision loss are being reported. This article aims to review the role of HA fillers, as a subgroup separate from fat graft and non-HA fillers, in causing vision loss and to elucidate various features and outcomes of post-HA filler vision loss.MethodsThe preferred reporting...
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Thu Dec 12, 2019 08:39
Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,00306932607174,alsfakia@gmail.com, Telephone consultation 11855 int 1193,
Food SecurityFood security impacts of industrial crop production in sub-Saharan Africa: a systematic review of the impact mechanismsAbstractA number of industrial crops have been promoted in sub-Saharan Africa (SSA) to meet a range of policy objectives including economic growth, rural development, agricultural modernization and energy security. The food security impacts of industrial crop production have received extensive policyattention and have been widely discussed in the academic literature....
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Wed Dec 11, 2019 10:19

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