Anterior cerebral artery trifurcation with infraoptic origin and contralateral A1 segment absence

xlomafota13 shared this article with you from Inoreader Anterior cerebral artery trifurcation with infraoptic origin and contralateral A1 segment absence Via radiol anat Surg Radiol Anat. 2021 Nov 6. doi: 10.1007/s00276-021-02855-x. Online ahead of print. ABSTRACT PURPOSE: To describe an uncommon anatomical variant of the anterior cerebral artery and the imaging findings. METHODS: A 2-month-old infant with known history of atrial and ventricular septal defects was admitted to our institution for evaluation and management of growth failure. Given the clinical presentation and medical history, magnetic resonance imaging (MRI) of the brai n and MR angiography (MRA) were performed to exclude congenital hypopituitarism and any vascular abnormality. RESULTS: Time of flight MRA revealed trifurcation of the anterior cerebral artery with one of the vessels arising from the ophthalmic segment of the right internal carotid artery; thus, the A1 segment of the left anterior cerebral artery (ACA) was absent, and the right posterior cerebral artery (PCA) had a fetal origin. CONCLUSION: Anatomical variants of the cerebral circulation are asymptomatic and found incidentally. Knowledge of these variants and careful examination of CT/MRI angiograms are important for diagnosis and treatment planning. PMID:34741640 | DOI:10.1007/s00276-021-02855-x View on the web Inoreader. Take back control of your news feed. Follow us on Twitter and Facebook.

A comparison between abdominal based and inner thigh based free flaps in breast reconstruction: A single surgeon's experience

xlomafota13 shared this article with you from Inoreader A comparison between abdominal based and inner thigh based free flaps in breast reconstruction: A single surgeon's experience Via Journal of plastic, reconstructive & aesthetic surgery : JPRAS J Plast Reconstr Aesthet Surg. 2021 Oct 22:S1748-6815(21)00487-3. doi: 10.1016/j.bjps.2021.09.048. Online ahead of print. NO ABSTRACT PMID:34742658 | DOI:10.1016/j.bjps.2021.09.048 View on the web Inoreader. Take back control of your news feed. Follow us on Twitter and Facebook.

Acute appendicitis secondary to desmoplastic melanoma metastasis in immune-checkpoint inhibitors era

xlomafota13 shared this article with you from Inoreader Acute appendicitis secondary to desmoplastic melanoma metastasis in immune-checkpoint inhibitors era Via Melanoma Research - Current Issue No abstract available View on the web Inoreader. Take back control of your news feed. Follow us on Twitter and Facebook.

Diagnostic and prognostic value of Beclin 1 expression in melanoma: a meta-analysis

xlomafota13 shared this article with you from Inoreader Diagnostic and prognostic value of Beclin 1 expression in melanoma: a meta-analysis Via Melanoma Research - Current Issue Autophagy plays a complicated role in the occurrence and development of cancer. Beclin 1 is a significant autophagy-related protein that plays an essential role in tumorigenesis, but its expression is controversial in melanoma. In this meta-analysis, we searched seven studies involving 638 melanoma patients. PubMed, Web of Science, Google Scholar, Elsevier, and Chinese National Knowledge Infrastructure were used for literature retrieval. The I2 index was used to assess heterogeneity. The expression of Beclin 1 in the primary melanoma group was significantly lower than the non-tumor group tissues (P 0.05). Different expres sion intensities of Beclin 1 did not affect the overall survival and disease-free survival of melanoma patients. This study showed a trend of low expression of Beclin 1 in melanoma; patients with low expression of Beclin 1 were prone to the possibility of distant metastasis. The inconsistent profile of Beclin 1 expression in the prognosis of melanoma patients warrants further clinical investigation. View on the web Inoreader. Take back control of your news feed. Follow us on Twitter and Facebook.

Novel strategy for applying hierarchical density-based spatial clustering of applications with noise towards spectroscopic analysis and detection of melanocytic lesions

xlomafota13 shared this article with you from Inoreader Novel strategy for applying hierarchical density-based spatial clustering of applications with noise towards spectroscopic analysis and detection of melanocytic lesions Via Melanoma Research - Current Issue Advancements in dermoscopy techniques have elucidated identifiable characteristics of melanoma which revolve around the asymmetrical constitution of melanocytic lesions consequent of unfettered proliferative growth as a malignant lesion. This study explores the applications of hierarchical density-based spatial clustering of applications with noise (HDBSCAN) in terms of the direct diagnostic implications of applying agglomerative clustering in the spectroscopic analysis of malignant melanocytic lesions and benign dermatologic spots. 100 images of benign (n = 50) and malignant moles (n = 50) were sampled from the Inter national Skin Imaging Collaboration Archive and processed through two separate Python algorithms. The first of which deconvolutes the three-digit tupled integer identifiers of pixel color in image composition into three separate matrices corresponding to the red, green and blue color channel. Statistical characterization of integer variance was utilized to determine the optimal channel for comparative analysis between malignant and benign image groups. The second applies HDBSCAN to the matrices, identifying agglomerative clustering in the dataset. The results indicate the potential diagnostic applications of HDBSCAN analysis in fast-processing dermoscopy, as optimization of clustering parameters according to a binary search strategy produced an accuracy of 85% in the classification of malignant and benign melanocytic lesions. View on the web Inoreader. Take back control of your news feed. Follow us on Twitter and Facebook.

Progressive Protrusive Tongue Exercise Does Not Alter Aging Effects in Retrusive Tongue Muscles

xlomafota13 shared this article with you from Inoreader Progressive Protrusive Tongue Exercise Does Not Alter Aging Effects in Retrusive Tongue Muscles Via swallowing exercises Front Physiol. 2021 Oct 21;12:740876. doi: 10.3389/fphys.2021.740876. eCollection 2021. ABSTRACT Purpose: Exercise-based treatment approaches for dysphagia may improve swallow function in part by inducing adaptive changes to muscles involved in swallowing and deglutition. We have previously shown that both aging and progressive resistance tongue exercise, in a rat model, can induce biological changes in the genioglossus (GG); a muscle that elevates and protrudes the tongue. However, the impacts of progressive resistance tongue exercise on the retrusive muscles (styloglossus, SG; hyoglossus, HG) of the tongue are unknown. The purpose of this study was to examine the impact of a progressive resistance tongue exercise regimen on the retrusive tongue musculature in the context of aging. Given that aging alters retrusive tongue muscles to more slowly contracting fiber types, we hypothesized that these biological changes may be mitigated by tongue exercise. Methods: Hyoglossus (HG) and styloglossus (SG) muscles of male Fischer 344/Brown Norway rats were assayed in age groups of young (9 months old, n = 24), middle-aged (24 months old, n = 23), and old (32 months old, n = 26), after receiving an 8-week period of either progressive resistance protrusive tongue exercise, or sham exercise conditions. Following exercise, HG and SG tongue muscle contractile properties were assessed in vivo. HG and SG muscles were then isolated an d assayed to determine myosin heavy chain isoform (MyHC) composition. Results: Both retrusive tongue muscle contractile properties and MyHC profiles of the HG and SG muscles were significantly impacted by age, but were not significantly impacted by tongue exercise. Old rats had significantly longer retrusive tongue contraction times and longer decay times than young rats. Additionally, HG and SG muscles showed significant MyHC profile changes with age, in that old groups had slower MyHC profiles as compared to young groups. However, the exercise condition did not induce significant effects in any of the biological outcome measures. Conclusion: In a rat model of protrusive tongue exercise, aging induced significant changes in retrusive tongue muscles, and these age-induced changes were unaffected by the tongue exercise regimen. Collectively, results are compatible with the interpretation that protrusive tongue exercise does not induce changes to retrusive tongue muscle function. PMID:34744782 | PMC:PMC8567011 | DOI:10.3389/fphys.2021.740876 View on the web Inoreader. Take back control of your news feed. Follow us on Twitter and Facebook.

Congenital Hypothyroidism Can Dictate the Mode of Delivery and Intra-Labor Medication Usage

xlomafota13 shared this article with you from Inoreader Congenital Hypothyroidism Can Dictate the Mode of Delivery and Intra-Labor Medication Usage Via liebertpub1 Thyroid, Ahead of Print. View on the web Inoreader. Take back control of your news feed. Follow us on Twitter and Facebook.