Σάββατο, 20 Ιουλίου 2019

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,00306932607174,alsfakia@gmail.com,


The Egyptian Orthopaedic Journal
Mini-open repair for acute Achilles tendon rupture using the ring forceps techniqueHatem S.A Elgohary, Mhmod A ElghafarThe Egyptian Orthopaedic Journal 2018 53(4):285-291Background Treatment of acute closed rupture of the tendo-Achilles is a challenge for the orthopedic surgeons. The aim of this study was to assess the results of repairing the tendo-Achilles using the ring forceps technique through a mini-open approach. Patients and methods A total of 21 adult patients with a closed rupture of the...
Αλέξανδρος Γ. Σφακιανάκης
3m
Multimodality imaging diagnosis of multiple ventricular thrombosis and massive stroke after gemcitabine...
Multimodality imaging diagnosis of multiple ventricular thrombosis and massive stroke after gemcitabine and cisplatin chemotherapy for Urothelial CancerPier Paolo Bassareo1, Daniele Cocco2, Christian Cadeddu2, Giuseppe Mercuro21 Department of Cardiology, University College of Dublin, Mater Misericordiae University Hospital, Dublin, Republic of Ireland; Department of Medical Sciences and Public Health, University of Cagliari, Monserrato, Italy2 Department of Medical Sciences and Public Health, University...
Αλέξανδρος Γ. Σφακιανάκης
4m
Giant right ventricular mass protruding into the pulmonary artery during systole, Yavuzer Koza1, Umit...
Giant right ventricular mass protruding into the pulmonary artery during systole,Yavuzer Koza1, Umit Arslan2, Bilgehan Erkut2, Enise Armagan Koza31 Department of Cardiology, Faculty of Medicine, Ataturk University, Erzurum, Turkey2 Department of Cardiology and Cardiovascular Surgery, Faculty of Medicine, Ataturk University, Erzurum, Turkey3 Department of Anesthesiology, Erzurum Regional Training and Research Hospital, Erzurum, TurkeyCorrespondence Address:Yavuzer KozaDepartment of Cardiology, Faculty...
Αλέξανδρος Γ. Σφακιανάκης
5m
Cardiovascular Echography
The Intrusive nature of epicardial adipose tissue as revealed by cardiac magnetic resonanceLaura Anna Leo, Vera Lucia Paiocchi, Susanne Anna Schlossbauer, Siew Yen Ho, Francesco F FaletraJournal of Cardiovascular Echography 2019 29(2):45-51The epicardial adipose tissue (EAT) refers to the deposition of adipose tissue fully enclosed by the pericardial sac. EAT has a complex mixture of adipocytes, nervous tissue, as well as inflammatory, stromal and immune cells secreting bioactive molecules. This...
Αλέξανδρος Γ. Σφακιανάκης
7m
Evaluatıon of hypofractıonated stereotactıc radıotherapy (HFSRT) to the resectıon cavıty after surgıcal...
Evaluatıon of hypofractıonated stereotactıc radıotherapy (HFSRT) to the resectıon cavıty after surgıcal resectıon of braın metastases: A sıngle center experıenceFerrat Dincoglan, Omer Sager, Bora Uysal, Selcuk Demiral, Hakan Gamsiz, Esin Gündem, Yelda Elcim, Bahar Dirican, Murat BeyzadeogluIndian Journal of Cancer 2019 56(3):202-206INTRODUCTON: Adjuvant radiotherapy after surgical resection is used for the treatment of patients with brain metastasis. In this study, we assessed the use of adjuvant...
Αλέξανδρος Γ. Σφακιανάκης
8m
Indian Journal of Cancer
Shared decision making and cancer screeningFilipe Prazeres, Elisa MartinsIndian Journal of Cancer 2019 56(3):195-196WT1 in astrocytomas: Comprehensive evaluation of immunohistochemical expression and its potential utility in different histological gradesAakriti Manocha, Sunila JainIndian Journal of Cancer 2019 56(3):197-201BACKGROUND: Wilms' tumor 1 (WT1) mutation has recently been detected in gliomas. Growing data indicate that WT1 mutation plays a causal role in gliomagenesis and is overexpressed...
Αλέξανδρος Γ. Σφακιανάκης
9m
Case Studies for Public Health in the Eastern Mediterranean Region - 2019,The Eastern Mediterranean...
Case Studies for Public Health in the Eastern Mediterranean Region - 2019,The Eastern Mediterranean Public Health Network (EMPHNET) helped to launch and establish several Field Epidemiology Training Programs (FETPs) in the Eastern Mediterranean Region (EMR). EMPHNET continues to provide ongoing technical and programmatic support for these program in an effort to assist countries to strengthen their public health workforce. READ MORE
Αλέξανδρος Γ. Σφακιανάκης
10m
WHO Response to Disease Outbreaks in Liberia: Lessons learned from the 2014 - 2015 Ebola Virus Disease...
WHO Response to Disease Outbreaks in Liberia: Lessons learned from the 2014 - 2015 Ebola Virus Disease OutbreakThis special issue of the Pan African Medical Journal documents the successful application of lesson learnt from response to the Ebola virus disease outbreak in Liberia and identifies some best practices that could be applied to other disease prevention, control and elimination programmes with similar success. The papers, written by those who were actively engaged in response to epidemics...
Αλέξανδρος Γ. Σφακιανάκης
11m
Nigerian Medical Journal
The role of preoperative evaluations in otorhinolayngological proceduresWaheed Atilade Adegbiji, Gabriel Toye Olajide, Fatai Olatoke, Olubunmi Kolawole Ogundipe, Sulyman Biodun AlabiNigerian Medical Journal 2018 59(6):59-63Background: Routine laboratory investigations are important in preoperative preparation of otorhinolaryngological, head and neck patients to assess and to prevent operative risks. This study aimed at determining the American Society of Anesthesiologist (ASA) classification of the...
Αλέξανδρος Γ. Σφακιανάκης
13m
New data on crinoid assemblages from the oldest sedimentary rocks of the Polish Outer Carpathians (Jurassic-Cretaceous)...
New data on crinoid assemblages from the oldest sedimentary rocks of the Polish Outer Carpathians (Jurassic-Cretaceous)Publication date: Available online 29 June 2019Source: Annales de PaléontologieAuthor(s): Mariusz A. Salamon, Bruno Ferré, Andrzej Szydło, Tomasz Brachaniec, Miroslav BubíkAbstractCrinoids (Crinoidea) preserved in the so-called Cieszyn Beds (Tithonian-Hauterivian; southern Poland) are relatively numerous, especially in some levels, but not highly diversified. They are absent in the...
Αλέξανδρος Γ. Σφακιανάκης
14m
The Arab Journal of Interventional Radiology
Interventional radiology evolution: Our past guides us to our futureJames F BenenatiThe Arab Journal of Interventional Radiology 2019 3(2):39-40The pan Arab interventional radiology society: Renaissance and researchMohammad ArabiThe Arab Journal of Interventional Radiology 2019 3(2):41-41The status of vascular and interventional radiology training: The Saudi experienceYousof AbdulRahman Al Zahrani, Mohammad Arabi, Mohammad AlmoaiqelThe Arab Journal of Interventional Radiology 2019 3(2):42-43Adrenal...
Αλέξανδρος Γ. Σφακιανάκης
14m
H&N
National Cancer Institute theNCI19 JulHead and neck cancers include cancers in the larynx, throat, lips, mouth, nose, and salivary glands. An overview:… https://t.co/8k888IUUixDetails  |  RetweetNational Cancer Institute theNCI18 JulRT @NCIKerlavage: Calling developers and cancer informaticists: submit a proposal to build the #CancerData Aggregator, a software service t…Details  |  RetweetNational Cancer Institute theNCI18 JulIn children with acute myeloid #leukemia, the bone marrow makes a large...
Αλέξανδρος Γ. Σφακιανάκης
15m
OncologyEducation is proud to present our ASCO 2019 Roundtable Discussions. These videos incorporate both...
OncologyEducation is proud to present our ASCO 2019 Roundtable Discussions.These videos incorporate both Canadian and international perspectives from our faculty of experts with updates on key data presented at this year's meeting.We invite you to view our Roundtable Discussions.Please enjoy and share with your colleagues.To view the videos, click the images below:Click here for more video updates from ASCO 2019
Αλέξανδρος Γ. Σφακιανάκης
16m
The profound oral cavity cancer burden in the United States Commonwealth of the Northern Mariana Islands:...
The profound oral cavity cancer burden in the United States Commonwealth of the Northern Mariana Islands: A global health opportunityAuthor links open overlay panelAjay M.NarayananaAndreyFinegershbMary P.ChangcJoanneOgodRyan K.OroscobWilliam J.MossdaUniversity of Texas Southwestern Medical Center, Dallas, TX 75390, United States of AmericabUniversity of California, San Diego, Department of Surgery, Division of Otolaryngology-Head & Neck Surgery, San Diego, CA 92103, United States of AmericacDepartment...
Αλέξανδρος Γ. Σφακιανάκης
16m
Multilingualism, Multiculturalism, and Migration: A Critical Assessment  Josue David Cisneros
Multilingualism, Multiculturalism, and Migration: A Critical Assessment  Josue David Cisneros
Αλέξανδρος Γ. Σφακιανάκης
18m
Footprints of War: Militarized Landscapes in Vietnam. By David Biggs,  David Hunt  Irish Presbyterians...
Footprints of War: Militarized Landscapes in Vietnam. By David Biggs,  David Hunt  Irish Presbyterians and the Shaping of Western Pennsylvania, 1770-1830. By Peter E. Gilmore  Kerby A Miller  Selling the Sights: The Invention of the Tourist in American Culture. By Will B. Mackintosh  Anthony J Stanonis  Race Women Internationalists: Activist-Intellectuals and Global Freedom Struggles. By Imaobong D. Umoren  Nicole M Jackson
Αλέξανδρος Γ. Σφακιανάκης
18m
Long-term c-Kit overexpression in beta cells compromises their function
 in ageing mice,AbstractAims/hypothesisc-Kit signalling regulates intracellular pathways that enhance beta cell proliferation, insulin secretion and islet vascularisation in mice up to 28 weeks of age and on short-term high-fat diet. However, long-term c-Kit activation in ageing mouse islets has yet to be examined. This study utilises beta cell-specific c-Kit-overexpressing transgenic (c-KitβTg) ageing mice (~60 weeks) to determine the effect of its activation on beta cell dysfunction and insulin...
Αλέξανδρος Γ. Σφακιανάκης
18m
Concordance of glycaemic and cardiometabolic traits between Indian women with history of gestational...
Concordance of glycaemic and cardiometabolic traits between Indian women with history of gestational diabetes mellitus and their spouses: an opportunity to target the householdAbstractAims/hypothesisThe aim of this study was to investigate the concordance of dysglycaemia (prediabetes or diabetes) and cardiometabolic traits between women with a history of gestational diabetes mellitus (GDM) and their spouses.MethodsUsing hospital medical records, women with GDM (diagnosed between 2012 and 2016) and...
Αλέξανδρος Γ. Σφακιανάκης
19m
Consequences of being overweight or obese during pregnancy on diabetes in the offspring: a record linkage...
Consequences of being overweight or obese during pregnancy on diabetes in the offspring: a record linkage study in Aberdeen, ScotlandAbstractAims/hypothesisMaternal obesity in pregnancy is associated with cardiovascular disease and mortality rate in the offspring. We aimed to determine whether maternal obesity is also associated with increased incidence of type 2 and type 1 diabetes in the offspring, independently of maternal diabetes as a candidate mechanistic pathway.MethodsBirth records of 118,201...
Αλέξανδρος Γ. Σφακιανάκης
19m
Reversion from prediabetes to normoglycaemia and risk of cardiovascular disease and mortality: the...
Reversion from prediabetes to normoglycaemia and risk of cardiovascular disease and mortality: the Whitehall II cohort study,AbstractAims/hypothesisReversion from prediabetes to normoglycaemia is accompanied by an improvement in cardiovascular risk factors, but it is unclear whether this translates into a reduction in risk of cardiovascular disease (CVD) events or death. Hence, we studied the probability of reversion from prediabetes to normoglycaemia and the associated risk of future CVD and death...
Αλέξανδρος Γ. Σφακιανάκης
20m
Diabetologia
Correction to: In vivo imaging of type 1 diabetes immunopathology using eye-transplanted islets in NOD miceUnfortunately there is a mistake in the presentation of the affiliations in this paper.Reversion from prediabetes to normoglycaemia and risk of cardiovascular disease and mortality: the Whitehall II cohort studyAbstractAims/hypothesisReversion from prediabetes to normoglycaemia is accompanied by an improvement in cardiovascular risk factors, but it is unclear whether this translates into a reduction...
Αλέξανδρος Γ. Σφακιανάκης
20m
Influence of oral administration of Akkermansia muciniphila on the tissue distribution and gut microbiota...
Influence of oral administration of Akkermansia muciniphila on the tissue distribution and gut microbiota composition of acute and chronic cadmium exposure mice  Saisai Feng; Yang Liu; Yanyang Huang ; Jianxin Zhao; Hao Zhang ...
Αλέξανδρος Γ. Σφακιανάκης
21m
Polyclonal Campylobacter fetus infections among unrelated patients, Montevideo, Uruguay, 2013-2018,  Daniela...
Polyclonal Campylobacter fetus infections among unrelated patients, Montevideo, Uruguay, 2013-2018,  Daniela Costa; Laura Betancor; Pilar Gadea; Laura Cabezas; Leticia Caiata ...  On Measles, Vaccination, Social Media Activism and How to Win Back Our Role as our Patients' Best Advocates  Richard L Oehler, MD, FACP, FIDSA  Metagenomic Analysis of Microdissected Valvular Tissue for Etiologic Diagnosis of Blood Culture Negative Endocarditis  Matthieu Million; Maxime Gaudin; Cléa Melenotte; Lionel Chasson ; Sophie...
Αλέξανδρος Γ. Σφακιανάκης
21m
Molecular Neurobiology
Correction to: In Vitro Seeding Activity of Glycoform-Deficient Prions from Variably Protease-Sensitive Prionopathy and Familial CJD Associated with PrP V180I MutationThe original version of this article unfortunately contained a mistake. The email address Dr. Wen-Quan Zou, one of the corresponding authors should be written as "wxz6@case.edu" instead of "wxz@case.edu".Correction to: Role of Chronic Administration of Antidepressant Drugs in the Prenatal Stress-Evoked Inflammatory Response in the Brain...
Αλέξανδρος Γ. Σφακιανάκης
22m
Life Cycle Assessment
SETAC Europe Young Scientist LCA award 2019 for P. James JoyceAbstractAt the 29th SETAC Europe annual meeting, May 26–30, 2019, Helsinki (Finland), P. James Joyce received the SETAC Europe Young Scientist LCA Award 2019. James is an environmental scientist by formation (University of Cambridge/Imperial College London), and finished his PhD in 2019 (KTH Institute of Technology, Sweden). His PhD research focused on the environmental considerations related to valorization of Bauxite residue. Herein,...
Αλέξανδρος Γ. Σφακιανάκης
23m
Absolute War: Violence and Mass Warfare in the German Lands, 1792–1820 The People's Wars: Histories...
Absolute War: Violence and Mass Warfare in the German Lands, 1792–1820The People's Wars: Histories of Violence in the German Lands, 1820–1888  Leighton James 
Αλέξανδρος Γ. Σφακιανάκης
24m
Well-Being Assessment
Validation of the German Version of the Subjective Vitality Scale - a Cross-Sectional Study and a Randomized Controlled TrialAbstractOver the last decade, the concept of Subjective Vitality has gained popularity as one indicator of human well-being. However, today no valid instrument exists to measure Subjective Vitality in German speaking samples. To close this gap, we validated a German trait and state version of the Subjective Vitality Scale (Ryan and Frederick 1997). Study one (N = 632) used...
Αλέξανδρος Γ. Σφακιανάκης
24m
Forbidden Memories: Women's Experiences of 1965 in Eastern Indonesia. By Merry Koliman, Liliya Wetangterah,...
Forbidden Memories: Women's Experiences of 1965 in Eastern Indonesia. By Merry Koliman, Liliya Wetangterah, and Karen Campbell-Nelson (eds)  Chris Lundry  "You ask many questions, but you don't give many answers": Embracing the Mess in Conflict Studies Classrooms  Anna Sheftel
Αλέξανδρος Γ. Σφακιανάκης
26m
Letalität nach operativen Risikoeingriffen bei Zeugen Jehovas, ZusammenfassungHintergrund Patienten...
Letalität nach operativen Risikoeingriffen bei Zeugen Jehovas,ZusammenfassungHintergrundPatienten der Zeugen Jehovas (ZJ) lehnen die Transfusion von Fremdblut (FB) aus religiöser Überzeugung ab. Dennoch wünschen sich auch ZJ, von modernen Therapiekonzepten einschließlich großer Operationen profitieren zu können, ohne ein übertrieben hohes Letalitätsrisiko eingehen zu müssen. Das Krankenhaus Nordwest in Frankfurt am Main ist „Vertrauensklinik" der ZJ und führt jährlich etwa 100 operative Eingriffe...
Αλέξανδρος Γ. Σφακιανάκης
26m
Der Anaesthesist
Anästhesiologisches Management bei endovaskulärer SchlaganfalltherapieZusammenfassungBei akutem ischämischem Schlaganfall (AIS) bewahrt nur die rasche Rekanalisation der verschlossenen Hirnarterie den betroffenen Patienten vor einem schweren neurologischen Defizit oder sogar einem tödlichen Ausgang. Lange Zeit war lediglich eine systemische Lyse der einzige, zur Verfügung stehende kausale Ansatz. Nach den Publikationen mehrerer randomisierter, prospektiver Studien zum Einsatz der endovaskulären Thrombektomie...
Αλέξανδρος Γ. Σφακιανάκης
27m
Practical Shape,  Christine Swanton
Practical Shape,  Christine Swanton
Αλέξανδρος Γ. Σφακιανάκης
29m
Marie of France, Countess of Champagne, 1145–1198,  Tracy Adams  Enchanted Islands: Picturing the Allure...
Marie of France, Countess of Champagne, 1145–1198,  Tracy Adams  Enchanted Islands: Picturing the Allure of Conquest in Eighteenth-Century France  Carol E Harrison
Αλέξανδρος Γ. Σφακιανάκης
29m
Metformin enhances gefitinib efficacy by interfering with interactions between tumor-associated macrophages...
Metformin enhances gefitinib efficacy by interfering with interactions between tumor-associated macrophages and head and neck squamous cell carcinoma cells,AbstractBackgroundTumor-associated macrophages (TAMs) play an important role in drug resistance in many tumors, including head and neck squamous cell carcinoma (HNSCC). However, how TAMs interact with HNSCC cells to induce drug resistance, especially under hypoxic conditions, is unclear. In this study, we investigated the mechanism of TAM-induced...
Αλέξανδρος Γ. Σφακιανάκης
30m
Cellular Oncology
Curcumin: a potent agent to reverse epithelial-to-mesenchymal transitionAbstractBackgroundEpithelial-to-mesenchymal transition (EMT) is involved in tumor progression, invasion, migration and metastasis. EMT is a process by which polarized epithelial cells acquire motile mesothelial phenotypic features. This process is initiated by disassembly of cell-cell contacts through the loss of epithelial markers and replacement of these markers by mesenchymal markers. Reconstruction of the cytoskeleton and...
Αλέξανδρος Γ. Σφακιανάκης
30m
Academic Psychiatry
Correction to: The Use of Technology by Youth: Implications for Psychiatric EducatorsThis article was originally published electronically on the publisher's internet portal (currently SpringerLink) on November 16, 2018 with open access.Empowering Clinician-Educators with Chalk Talk Teaching ScriptsA Dark Spot on a White Canvas: Thoughts on Being a Black Academic PsychiatristChallenges and Perspectives to the Fall in Psychiatry Fellowship ApplicationsA Missed Opportunity: Universal School-Based Mental...
Αλέξανδρος Γ. Σφακιανάκης
32m
Does oral antiviral suppressive therapy prevent recurrent herpes labialis in children? Laure F Pittet1,...
Does oral antiviral suppressive therapy prevent recurrent herpes labialis in children?Laure F Pittet1, Nigel Curtis1,2,3Author affiliationsInfectious Diseases Unit, Royal Children's Hospital Melbourne, Parkville, Victoria, AustraliaDepartment of Pediatrics, The University of Melbourne, Parkville, Victoria, AustraliaInfectious Diseases Group, Murdoch Children's Research Institute, Parkville, Victoria, AustraliaCorrespondence toProfessor Nigel Curtis, Department of Paediatrics, The University of Melbourne,...
Αλέξανδρος Γ. Σφακιανάκης
33m
Involvement of the vermillion border in a severe case of periorificial dermatitis, Vance Tran1, Vinay...
Involvement of the vermillion border in a severe case of periorificial dermatitis,Vance Tran1, Vinay Kukreti2,3Author affiliationsDepartment of Family Medicine, Queen's University, Oshawa, Ontario, CanadaDepartment of Paediatrics, Queen's University, Kingston, Ontario, CanadaPaediatrics, Lakeridge Health Oshawa, Oshawa, Ontario, CanadaCorrespondence toDr Vinay Kukreti, Paediatrics, Lakeridge Health Oshawa, Ontario, Canada.L1G 2B9; vkukreti@lh.caView Full Texthttp://dx.doi.org/10.1136/archdischild-2019-317798Statistics...
Αλέξανδρος Γ. Σφακιανάκης
34m
Archives of Disease in Childhood
ArchimedesDoes oral antiviral suppressive therapy prevent recurrent herpes labialis in children?Laure F Pittet, Nigel Curtis (2019-07-16)10.1136/archdischild-2019-317249ViewpointSecond medical opinions in paediatric practice; proposals for a framework for best practiceVic Larcher, Joe Brierley (2019-07-18)10.1136/archdischild-2019-317223Original articleProfessionals' accounts of genetic testing in adoption: a qualitative studyMichael Arribas-Ayllon, Angus Clarke, Katherine Shelton (2019-07-11)10.1136/archdischild-2019-316911Waist...
Αλέξανδρος Γ. Σφακιανάκης
35m
Cerebral venous thrombosis: a rare complication of herpes simplex encephalitis, Abstract We report...
Cerebral venous thrombosis: a rare complication of herpes simplex encephalitis,AbstractWe report a case of classic HSE with early neurological relapse 7 days after onset of acyclovir treatment secondary to cerebral venous thrombosis (CVT). The development of CVT after meningoencephalitis has been described with neurotropic viruses such as HSV, HIV, or enteroviruses and also bacterial or fungal agents. CVT is probably the consequence of the inflammation secondary to these infections. A diagnosis of...
Αλέξανδρος Γ. Σφακιανάκης
36m

NeuroVirology
Polymorphisms in CAMKK2 associate with susceptibility to sensory neuropathy in HIV patients treated without stavudineAbstractHIV-associated sensory neuropathy (HIV-SN) is a debilitating neurological complication of HIV infection potentiated by the antiretroviral drug stavudine. While stavudine is no longer used, HIV-SN now affects around 15% of HIV+ Indonesians. Here, we investigate whether polymorphisms within the P2X-block (P2X4R, P2X7R, CAMKK2) and/or ANAPC5 mark susceptibility to HIV-SN in this...
Αλέξανδρος Γ. Σφακιανάκης
36m
JAMA
VIEWPOINTThe Conundrum of the United States Medical Licensing Examination Score Reporting StructureJennifer L. Swails, MD; Omowunmi Aibana, MD, MPH; Barbara J. Stoll, MDEvidence vs Consensus in Clinical Practice GuidelinesBenjamin Djulbegovic, MD, PhD; Gordon Guyatt, MD, MSTRENDING NOW ON JAMAAssociation of Lifestyle and Genetic Risk With Incidence of DementiaBasch Unbound—The House of God and Fiction as Resistance at 40Advances in Understanding the Pathophysiology of Chronic Fatigue SyndromeSubclinical...
Αλέξανδρος Γ. Σφακιανάκης
37m
Attention, Perception, & Psychophysics
Multisensory feature integration in (and out) of the focus of spatial attentionAbstractAnne Treisman transformed the way in which we think about visual feature integration. However, that does not mean that she was necessarily right, nor that she looked much beyond vision when considering how features might be bound together into perceptual objects. While such a narrow focus undoubtedly makes sense, given the complexity of human multisensory information processing, it is nevertheless somewhat surprising...
Αλέξανδρος Γ. Σφακιανάκης
38m
Hippo/Mst1 overexpression induces mitochondrial death in head and neck squamous cell carcinoma via...
Hippo/Mst1 overexpression induces mitochondrial death in head and neck squamous cell carcinoma via activating β-catenin/Drp1 pathway,AbstractMammalian Ste20-like kinase 1 (Mst1) is associated with cell apoptosis. In the current study, we explored the regulatory effects of Mst1 on squamous cell carcinoma of the head and neck (SCCHN) in vitro. SCCHN Cal27 cells and Tu686 cells were transfected with adenovirus-loaded Mst1 to detect the role of Mst1 in cell viability. Then, siRNA against Drp1 was transfected...
Αλέξανδρος Γ. Σφακιανάκης
39m
Cell Stress and Chaperones
Correction to: Superoxide dismutase activity as a predictor of adverse outcomes in patients with nonischemic dilated cardiomyopathyDue to an unfortunate turn of events, part of the data in the columns HR, 95% CI and p is missing from Figs. 4–9 of the original publication.Resveratrol and siRNA in combination reduces Hsp27 expression and induces caspase-3 activity in human glioblastoma cellsAbstractGBM cells can easily gain resistance to conventional therapy, and therefore treatment of glioblastoma...
Αλέξανδρος Γ. Σφακιανάκης
39m
Phase I study of ipatasertib as a single agent and in combination with abiraterone plus prednisolone...
Phase I study of ipatasertib as a single agent and in combination with abiraterone plus prednisolone in Japanese patients with advanced solid tumors,AbstractPurposeIpatasertib is a selective inhibitor of Akt, a frequently activated protein kinase in human cancers. The current study assessed the safety, tolerability, and pharmacokinetics of ipatasertib in Japanese patients with solid tumors.MethodsThis was a phase I, open-label, 3 + 3 dose-escalation study conducted in two stages. In stage I, Japanese...
Αλέξανδρος Γ. Σφακιανάκης
40m
Cancer Chemotherapy and Pharmacology
Effect of ethnicity on vinorelbine pharmacokinetics: a population pharmacokinetics analysisAbstractBackgroundPharmacokinetics of vinorelbine is mainly known from studies conducted in European patients. Interethnic differences in drug disposition may, however, induce interethnic variation in drug exposure. This paper aimed to evaluate the effect of ethnicity on the bioavailability and clearance of oral and intravenous vinorelbine.MethodsOral and intravenous vinorelbine pharmacokinetics data in Asian...
Αλέξανδρος Γ. Σφακιανάκης
40m
Mortality rates and prognostic factors in patients with malignant salivary tumors, Abstract Malignancies...
Mortality rates and prognostic factors in patients with malignant salivary tumors,AbstractMalignancies of the salivary glands represent a multifarious disease. Evaluating the prognostic factors of these malignancies may help predict patient outcome and aid decision-making in choosing the most suitable therapy. We examined the role of various salivary tumorigenic, clinical and therapeutic features in a cohort of 101 patients diagnosed and treated for primary malignant salivary tumors. These include...
Αλέξανδρος Γ. Σφακιανάκης
41m
Hypofractionated radiotherapy combined with cetuximab in vulnerable elderly patients with locally advanced...
Hypofractionated radiotherapy combined with cetuximab in vulnerable elderly patients with locally advanced head and neck squamous cell carcinoma,AbstractThis study was designed to evaluate the objective response after hypofractionated radiotherapy (HFRT) combined with cetuximab (HFBRT) in vulnerable elderly patients with locally advanced head and neck squamous cell carcinoma (HNSCC). Vulnerable elderly patients with histologically proven HNSCC received HFRT (total dose 60 Gy, 3 Gy/fraction) with...
Αλέξανδρος Γ. Σφακιανάκης
41m
Oncology
Identification of important invasion and proliferation related genes in adrenocortical carcinomaAbstractAdrenocortical carcinoma (ACC) is an end‐stage hormonal syndrome. Although profound attempts have been made to illuminate the pathogenesis, the molecular mechanisms of ACC remain to be clarified. To identify the important genes in the progression of ACC, microarray datasets GSE19775 was downloaded from the gene expression omnibus database. The differentially-expressed genes (DEGs) were identified,...
Αλέξανδρος Γ. Σφακιανάκης
42m
Based on electron microscopic (EM) imagery, this illustration provides a three-dimensional (3D),...
Based on electron microscopic (EM) imagery, this illustration provides a three-dimensional (3D), graphical representation of a number of norovirus virions, set against a black background.More Info
Αλέξανδρος Γ. Σφακιανάκης
43m
Archives of Disease in Childhood
EditorialPalivizumab for children with Down syndrome: is the time right for a universal recommendation?Bosco Paes, Souvik MitraChanging practice and altering national policy—selective dorsal rhizotomyGlobal child healthCharging undocumented migrant children for NHS healthcare: implications for child healthNeal James Russell, Lisa Murphy, Laura Nellums et al.Growth of preterm infants at the time of global obesityJosé Villar, Francesca Giuliani, Josep Figueras-Aloy et al.Adolescent healthDeliberate...
Αλέξανδρος Γ. Σφακιανάκης
43m
Neurosciences in the ninth art
Neurological SciencesAugust 2019, Volume 40, Issue 8, pp 1749–1750| Cite asAuthorsAuthors and affiliationsMichele Augusto Riva1Email authorView author's OrcID profileAndrea Galli1Michael Belingheri11.School of Medicine and SurgeryUniversity of Milano-BicoccaMonzaItalyLetter to the EditorFirst Online: 25 February 20191Shares  42DownloadsDear Editor,Stan Lee (1922–2018), who recently passed away, was one of the most prolific comic book writers and publishers. He co-created numerous popular fictional...
Αλέξανδρος Γ. Σφακιανάκης
45m
Identification of a novel splice mutation in CTNNB1 gene in a Chinese family with both severe intellectual...
Identification of a novel splice mutation in CTNNB1 gene in a Chinese family with both severe intellectual disability and serious visual defects,AbstractThe CTNNB1 gene encode the β-catenin protein which is a core unit of the cadherin/catenin multiprotein complex. The loss-of-function mutation of the CTNNB1 gene recently has been confirmed as a cause of intellectual disability. Previous studies have found that patients with CTNNB1 gene mutation may have other clinical manifestation such as microcephaly,...
Αλέξανδρος Γ. Σφακιανάκης
46m
Sexual abuse and psychogenic nonepileptic seizures, AbstractObjective We investigated the frequency...
Sexual abuse and psychogenic nonepileptic seizures,AbstractObjectiveWe investigated the frequency of reported sexual abuse in patients with psychogenic nonepileptic seizures (PNES) in a Middle-Eastern culture (Iran) and tried to characterize the association between a history of sexual abuse and the clinical characteristics of PNES in these patients.MethodsIn this retrospective database study, patients with PNES, who were investigated at Shiraz Comprehensive Epilepsy Center at Shiraz University of...
Αλέξανδρος Γ. Σφακιανάκης
46m
Neurological Sciences
Correction to: Effect of taping on scapular kinematics of patients with facioscapulohumeral muscular dystrophyThe published version of this article unfortunately contained a mistake in Fig. 2. Only one graphic of different movement of scapula was published instead of three. The Figure is corrected here.Incidence and prevalence of Parkinson's disease in the Italian region of Umbria: a population-based study using healthcare administrative databasesAbstractParkinson's disease is known to pose a significant...
Αλέξανδρος Γ. Σφακιανάκης
46m
County lines: how gang crime is affecting our young people, 'County lines' is the term used for the...
County lines: how gang crime is affecting our young people,'County lines' is the term used for the proliferating mobile phone lines used by gangs to infiltrate county towns where a profitable drug market is identified. The National Crime Agency reports that 88% of police areas in England and Wales have either an established or emerging County Lines problem in [...]By Alessandra Glover Williams, Fiona Finlay
Αλέξανδρος Γ. Σφακιανάκης
46m
Urinary metabolites of polycyclic aromatic hydrocarbons in pregnant women and their association with...
Urinary metabolites of polycyclic aromatic hydrocarbons in pregnant women and their association with a biomarker of oxidative stress,AbstractExposure to polycyclic aromatic hydrocarbons (PAHs) during pregnancy may pose adverse health risk to both the mothers and babies. In the present study, 188 pregnant women of different trimesters were recruited in Guangzhou, south China, and nine hydroxyl PAHs (OH-PAHs) and a biomarker of DNA oxidative damage, 8-hydroxy-2′-deoxyguanosine (8-OHdG), were determined...
Αλέξανδρος Γ. Σφακιανάκης
48m
Commonly consumed freshwater fish,...,Vibrio cholerae
Virulence, antimicrobial and heavy metal tolerance, and genetic diversity of Vibrio cholerae recovered from commonly consumed freshwater fish,AbstractVibrio cholerae is a leading waterborne pathogen worldwide. Continuous monitoring of V. cholerae contamination in aquatic products and identification of risk factors are crucial for assuring food safety. In this study, we determined the virulence, antimicrobial susceptibility, heavy metal tolerance, and genetic diversity of 400 V. cholerae isolates...
Αλέξανδρος Γ. Σφακιανάκης
49m
Hairdressers are exposed to high concentrations of formaldehyde during the hair straightening procedure,...
Hairdressers are exposed to high concentrations of formaldehyde during the hair straightening procedure,AbstractThe fact that hairdressers are exposed to toxic substances through the handling of creams and smoothing products prompted this study whose aim was to quantify the occupational exposure of hairdressers to formaldehyde by comparing the results of exposure for different types of beauty salon. The study population consisted of 23 beauty salons located in the city of Bauru, São Paulo state,...
Αλέξανδρος Γ. Σφακιανάκης
50m

Green vehicle adoption behavior among low-income households
: evidence from coastal MalaysiaAbstractIn an attempt to mitigate the effects of extreme natural events caused by greenhouse gases (GHGs), a significant number of researchers and environmentalists have repeatedly stressed the importance of implementing protective measures, including the promotion of green consumption. This study examined the elements that motivated the willingness and the practice of green behavior (GB) among low-income households in coastal Peninsular Malaysia. To meet the research...
Αλέξανδρος Γ. Σφακιανάκης
51m
Fluorene-9-bisphenol inhibits epithelial-mesenchymal transition of human endometrial cancer Ishikawa...
Fluorene-9-bisphenol inhibits epithelial-mesenchymal transition of human endometrial cancer Ishikawa cells by repressing TGF-β signaling pathwayAbstractFluorene-9-bisphenol (BHPF), a new derivative of bisphenol A (BPA), has been introduced for treatment with estrogen-related tumors, such as endometrial cancer. This study investigated the potential mechanism underlying the action of BHPF against endometrial cancer in vitro. We used the cell counting kit-8 (CCK8) method on Ishikawa cells to screen...
Αλέξανδρος Γ. Σφακιανάκης
51m
Environmental Science and Pollution Research
Efficient microalgae removal from aqueous medium through auto-flocculation: investigating growth-dependent role of organic matterAbstractThis study investigated the growth-dependent role of algal organic matters (AOMs) to achieve high removal efficiency (R.E) of microalgae. The results showed that the microalgae cells produced 96 ± 2% of total AOMs as loose bound AOMSS (LB-AOMs) and 4 ± 1% as cell-bound (CB-AOMs) in exponential phase. In stationary phase, LB-AOMs and CB-AOMs were 46 ± 0.7percentage...
Αλέξανδρος Γ. Σφακιανάκης
51m
   Tragic Excess in Hamlet   Jeffrey Wilson  After Great Grief a Formal Feeling Comes: The Conclusion...
   Tragic Excess in Hamlet   Jeffrey Wilson  After Great Grief a Formal Feeling Comes: The Conclusion of Milton's Lycidas  John Savoie  Strings of Pearls: James, Maupassant, and "Paste"  Philip Horne  Physician, Heal Thyself: The Satiric Turn in Washington Square  Stewart Justman  Yeats's Presences  Francis O'Gorman  No Puzzle: James Merrill, Philosophical Poetry, and the Structure of the Self  V Joshua Adams  Tony Hoagland and Self-Criticism  Mark Halliday   Poetry   More Things in Heaven  David...
Αλέξανδρος Γ. Σφακιανάκης
52m
Intranasal infection by Cytomegalovirus (CMV)
Persistent viral replication and the development of T-cell responses after intranasal infection by MCMVAbstractNatural transmission of cytomegalovirus (CMV) has been difficult to observe. However, recent work using the mouse model of murine (M)CMV demonstrated that MCMV initially infects the nasal mucosa after transmission from mothers to pups. We found that intranasal (i.n.) inoculation of C57BL/6J mice resulted in reliable recovery of replicating virus from the nasal mucosa as assessed by plaque...
Αλέξανδρος Γ. Σφακιανάκης
53m
Cytomegalovirus (CMV) infection
Adverse immunological imprinting by cytomegalovirus sensitizing for allergic airway diseaseAbstractCytomegalovirus (CMV) infection has a profound impact on the host's immune system. Immunological imprinting by CMV is not restricted to immunity against CMV itself, but can affect immunity against other viral or non-viral infectious agents and also immunopathological responses. One category is heterologous immunity based on molecular mimicry, where antigen recognition receptors specific for a CMV antigen...
Αλέξανδρος Γ. Σφακιανάκης
54m
Role of antibodies in confining cytomegalovirus after reactivation from latency: three decades' résumé,...
Role of antibodies in confining cytomegalovirus after reactivation from latency: three decades' résumé,AbstractCytomegaloviruses (CMVs) are highly prevalent herpesviruses, characterized by strict species specificity and the ability to establish non-productive latent infection from which reactivation can occur. Reactivation of latent human CMV (HCMV) represents one of the most important clinical challenges in transplant recipients secondary to the strong immunosuppression. In addition, HCMV is the...
Αλέξανδρος Γ. Σφακιανάκης
55m
Adverse immunological imprinting by cytomegalovirus sensitizing for allergic airway disease, Abstract...
Adverse immunological imprinting by cytomegalovirus sensitizing for allergic airway disease,AbstractCytomegalovirus (CMV) infection has a profound impact on the host's immune system. Immunological imprinting by CMV is not restricted to immunity against CMV itself, but can affect immunity against other viral or non-viral infectious agents and also immunopathological responses. One category is heterologous immunity based on molecular mimicry, where antigen recognition receptors specific for a CMV antigen...
Αλέξανδρος Γ. Σφακιανάκης
56m
Adverse immunological imprinting by cytomegalovirus sensitizing for allergic airway disease, Abstract...
Adverse immunological imprinting by cytomegalovirus sensitizing for allergic airway disease,AbstractCytomegalovirus (CMV) infection has a profound impact on the host's immune system. Immunological imprinting by CMV is not restricted to immunity against CMV itself, but can affect immunity against other viral or non-viral infectious agents and also immunopathological responses. One category is heterologous immunity based on molecular mimicry, where antigen recognition receptors specific for a CMV antigen...
Αλέξανδρος Γ. Σφακιανάκης
1h
   Fosfomycin tromethamine activity on biofilm and intracellular bacterial communities produced by...
   Fosfomycin tromethamine activity on biofilm and intracellular bacterial communities produced by uropathogenic Escherichia coli isolated from patients with urinary tract infection  Maria José González; Paula Da Cunda; Martín Notejane ; Pablo Zunino; Paola Scavone ... Fosfomycin tromethamine reduces uropathogenic Escherichia coli biofilm, without activity on intracellular bacterial communities within the bladder.  Human papillomavirus infection and autoimmune disorders: a tertiary center experience  Hanife...
Αλέξανδρος Γ. Σφακιανάκης
1h
Medical Microbiology and Immunology
Adverse immunological imprinting by cytomegalovirus sensitizing for allergic airway diseaseAbstractCytomegalovirus (CMV) infection has a profound impact on the host's immune system. Immunological imprinting by CMV is not restricted to immunity against CMV itself, but can affect immunity against other viral or non-viral infectious agents and also immunopathological responses. One category is heterologous immunity based on molecular mimicry, where antigen recognition receptors specific for a CMV antigen...
Αλέξανδρος Γ. Σφακιανάκης
1h
Laboratory Evaluation of Spasmodic Dysphonia, Publication date: Available online 6 July 2019 Source: Journal...
Laboratory Evaluation of Spasmodic Dysphonia,Publication date: Available online 6 July 2019Source: Journal of VoiceAuthor(s): Sammy Othman, Srihari Daggumati, Rohan Patel, Justin Ross, Robert T. SataloffSummaryObjectivesTo evaluate the utility of comprehensive laboratory evaluation in patients with spasmodic dysphonia (SD).Study DesignRetrospective chart review.MethodsA review of the medical records of 40 patients diagnosed with spasmodic dysphonia from 2009-2018 was preformed to evaluate abnormal...
Αλέξανδρος Γ. Σφακιανάκης
1h
Monitoring Breathing Muscle Performance During Singing Noninvasively Using Mechanomyography and Electromyography,...
Monitoring Breathing Muscle Performance During Singing Noninvasively Using Mechanomyography and Electromyography,Publication date: Available online 9 July 2019Source: Journal of VoiceAuthor(s): Muhammad Imran Ramli, Nur Azah Hamzaid, Julia Patrick EngkasanAbstractObjectivesThe aim of this study was to investigate the performance of mechanomyography (MMG) and electromyography (EMG) in monitoring the sternocleidomastoid (SCM) as accessory respiratory muscles when breathing during singing.MethodsMMG...
Αλέξανδρος Γ. Σφακιανάκης
1h
The Voice Disability Coping Questionnaire
Factor Analysis of the Persian Version of the Voice Disability Coping QuestionnairePublication date: Available online 16 July 2019Source: Journal of VoiceAuthor(s): Farzaneh Salehimanesh, Majid Soltani, Maryam Dastoorpoor, Negin MoradiAbstractIntroductionVoice disorders can affect the quality of life and coping mechanisms and also coping mechanisms can affect the way in which patients deal with their voice problems. People with voice disorders need to use coping strategies to deal with the problems...
Αλέξανδρος Γ. Σφακιανάκης
1h
Laryngeal hypersensitivity : Laryngeal pesthesia Questionnaire,...................,LHQ: Laryngeal hypersensitivity questionnaire; PVFM: Paradoxical vocal fold movement.,.....................,Laryngeal Dysfunction Syndromes include chronic refractory cough, pdoxical vocal fold movement (vocal cord dysfunction), muscle tension dysphonia and globus pharyngeus. These conditions present to clinicians as discrete syndromes based around a dominant manifestation of a disordered laryngeal adductor reflex, e.g. cough, vocal fold closure, vocalisation, or swallowing.
Abnormal sensory experience is characterised in three ways: (1) hypersensory–sensation triggered by stimuli that is sub-threshold for triggering that sensation, (2) pesthesia–altered sensory experience, and (3) allodynia–sensation triggered by stimuli that do not normally trigger those sensations.Patients with laryngeal dysfunction syndromes such as chronic refractory cough, paradoxical vocal fold movement, globus pharyngeus and muscle tension dysphonia frequently report irritation and discomfort...
Αλέξανδρος Γ. Σφακιανάκης
1h
The Newcastle Laryngeal Hypersensitivity Questionnaire
Cough. 2014; 10: 1.Published online 2014 Feb 19. doi: 10.1186/1745-9974-10-1PMCID: PMC3931290PMID: 24552215Development and validation of the Newcastle laryngeal hypersensitivity questionnaireAnne E Vertigan,corresponding author1,2,3 Sarah L Bone,1,2 and Peter G Gibson2,3,4Author information Article notes Copyright and License information DisclaimerThis article has been cited by other articles in PMC.Go to:AbstractBackgroundLaryngeal hypersensitivity may be an important component of the common disorders...
Αλέξανδρος Γ. Σφακιανάκης
1h
Dehydration and Estrous Staging in the Rat Larynx: an in vivo Prospective Investigation, Publication...
Dehydration and Estrous Staging in the Rat Larynx: an in vivo Prospective Investigation,Publication date: Available online 13 July 2019Source: Journal of VoiceAuthor(s): Abigail Cox, Naila Cannes do Nascimento, Andrea Pires dos Santos, M. Preeti SivasankarAbstractObjectiveThis novel study sought to untangle the association between hydration state and the estrous cycle in the vocal folds, since the voice is reported to negatively change in speakers during the estrous cycle and with dehydration. We...
Αλέξανδρος Γ. Σφακιανάκης
1h
Intraglottal Pressure: A Comparison Between Male and Female Larynxes, Publication date: Available...
Intraglottal Pressure: A Comparison Between Male and Female Larynxes,Publication date: Available online 13 July 2019Source: Journal of VoiceAuthor(s): Sheng Li, Ronald C. Scherer, MingXi Wan, SuPin Wang, Bo SongSummaryAcoustic differences in the phonated sounds made by men and women are related to laryngeal and vocal tract structural differences. This model-based study explored how typical vocal fold differences between males and females affect intraglottal pressure distributions under conditions...
Αλέξανδρος Γ. Σφακιανάκης
1h
Long-Term Effects of a Voice Training Program to Prevent Voice Disorders in Teachers, Publication...
Long-Term Effects of a Voice Training Program to Prevent Voice Disorders in Teachers,Publication date: Available online 13 July 2019Source: Journal of VoiceAuthor(s): Birte Meier, Ulla BeushausenAbstractObjectivesResearch findings about long-term effectiveness of voice training programs for teachers are limited. This study shows long-term evaluation results of a statewide voice training program for teachers in Lower Saxony/Germany.MethodTwenty-seven voice training sessions with 286 participating...
Αλέξανδρος Γ. Σφακιανάκης
1h
Vocal Fold "Paralysis": An Early Sign in Multiple System Atrophy, Publication date: Available online...
Vocal Fold "Paralysis": An Early Sign in Multiple System Atrophy,Publication date: Available online 16 July 2019Source: Journal of VoiceAuthor(s): Philip W. Tipton, Dale C. Ekbom, Amy L. Rutt, Jay A. van GerpenSummaryMultiple system atrophy (MSA) is a neurodegenerative disease characterized by a cerebellar syndrome, autonomic dysfunction, and extrapyramidal signs. Extrapyramidal signs may manifest as parkinsonism as well as dystonia, which is the involuntary contraction of a muscle(s) resulting in...
Αλέξανδρος Γ. Σφακιανάκης
1h

Neuroblastoma in relation to joint effects of vitamin A and maternal and offspring variants in vitamin...
Neuroblastoma in relation to joint effects of vitamin A and maternal and offspring variants in vitamin A-related genes: A report of the Children's Oncology GroupPublication date: August 2019Source: Cancer Epidemiology, Volume 61Author(s): Angela L. Mazul, Clarice R. Weinberg, Stephanie M. Engel, Anna Maria Siega-Riz, Fei Zou, Kathryn S. Carrier, Patricia V. Basta, Zalman Vaksman, John M. Maris, Sharon J. Diskin, Charlene Maxen, Arlene Naranjo, Andrew F. OlshanAbstractBackgroundThere is evidence vitamin...
Αλέξανδρος Γ. Σφακιανάκης
1h
Defining a mutational signature for endometrial cancer screening and early detection Publication date:...
Defining a mutational signature for endometrial cancer screening and early detectionPublication date: August 2019Source: Cancer Epidemiology, Volume 61Author(s): Laura Costas, Luis Palomero, Yolanda Benavente, Magdalena Guardiola, Jon Frias-Gomez, Miquel Ángel Pavón, Maite Climent, José Manuel Martinez, Marc Barahona, Mónica Salinas, Marta Pineda, Ilaria Bianchi, Jaume Reventós, Gabriel Capellà, Mireia Diaz, August Vidal, Josep Maria Piulats, Jordi Ponce, Joan Brunet, Francesc Xavier BoschAbstractIntroductionThe...
Αλέξανδρος Γ. Σφακιανάκης
1h
Screening baseline characteristics of early lung cancer on low-dose computed tomography with computer-aided...
Screening baseline characteristics of early lung cancer on low-dose computed tomography with computer-aided detection in a Chinese populationPublication date: October 2019Source: Cancer Epidemiology, Volume 62Author(s): Yuanyuan Liu, Hongbin Luo, Haomiao Qing, Xiaodong Wang, Jing Ren, Guohui Xu, Shibei Hu, Changjiu He, Peng ZhouAbstractObjectivesThis study investigated appropriate baseline characteristics for screening a Chinese population at high risk of early lung cancer, assisted by low-dose computed...
Αλέξανδρος Γ. Σφακιανάκης
1h
Corpus uteri cancer has become the fourth most common female cancer in Europe
Int J Gynaecol Obstet. 2018 Oct;143 Suppl 2:37-50. doi: 10.1002/ijgo.12612.Cancer of the corpus uteri.Amant F1,2,3, Mirza MR4, Koskas M5, Creutzberg CL6.Author information1Division of Gynecologic Oncology, University Hospitals Gasthuisberg, Leuven, Belgium.2Center for Gynecologic Oncology Amsterdam, Netherlands Cancer Institute, Amsterdam, Netherlands.3Center for Gynecologic Oncology Amsterdam, Amsterdam University Medical Centers, Amsterdam, Netherlands.4Department of Oncology, Rigshospitalet, Copenhagen...
Αλέξανδρος Γ. Σφακιανάκης
1h
A heavier weight at birth is associated with an elevated risk of total and follicular thyroid cancer, which underscores that prenatal exposures may be important in thyroid cancer aetiology.
https://sfakianakisorl.blogspot.com/2019/07/a-heavier-weight-at-birth-is-associated.htmlAlexandros SfakianakisAnapafseos 5 . Agios NikolaosCrete.Greece.7210028410261826948891480alsfakia@gmail.com
Αλέξανδρος Γ. Σφακιανάκης
1h
A heavier weight at birth is associated with an elevated risk of total and follicular thyroid cancer, which underscores that prenatal exposures may be important in thyroid cancer aetiology.
Birthweight and risk of thyroid cancer and its histological types: A large cohort studyPublication date: October 2019Source: Cancer Epidemiology, Volume 62Author(s): Julie Aarestrup, Cari M. Kitahara, Jennifer L. BakerAbstractBackgroundThe aetiology of thyroid cancer is poorly understood, but it is possible that this malignancy has origins early in life. It is, however, currently unknown if birthweight, as an indicator of prenatal growth, is related to thyroid cancer risk.ObjectiveTo investigate...
Αλέξανδρος Γ. Σφακιανάκης
1h
Cancer Epidemiology
Clinicopathologic and epidemiological characteristics of prognostic factors in post-surgical survival of colorectal cancer patients in Jiangsu Province, ChinaPublication date: October 2019Source: Cancer Epidemiology, Volume 62Author(s): Said Abasse Kassim, Weiyan Tang, Muhammad Abbas, Shenzhen Wu, Qingdao Meng, Chengcheng Zhang, Xiaobo Li, Rui ChenAbstractPoor survival among colorectal cancer (CRC) patients has been widely associated with clinico-epidemiological features and treatment regimen. In...
Αλέξανδρος Γ. Σφακιανάκης
1h
Journal of Voice
Reply to Functional Dysphonia: A Clear Need for Differential DiagnosisPublication date: Available online 18 July 2019Source: Journal of VoiceAuthor(s): Tamonud ModakFactor Analysis of the Persian Version of the Voice Disability Coping QuestionnairePublication date: Available online 16 July 2019Source: Journal of VoiceAuthor(s): Farzaneh Salehimanesh, Majid Soltani, Maryam Dastoorpoor, Negin MoradiAbstractIntroductionVoice disorders can affect the quality of life and coping mechanisms and also coping...
Αλέξανδρος Γ. Σφακιανάκης
1h
Acta Histochemica
Comparison of incremental concentrations of micron-sized superparamagnetic iron oxide for labelling articular cartilage derived chondroprogenitorsPublication date: Available online 18 July 2019Source: Acta HistochemicaAuthor(s): Elizabeth Vinod, Jithu Varghese James, Upasana Kachroo, Solomon Sathishkumar, Abel Livingston, Boopalan RamasamyAbstractIntroductionIn vivo tracking of labelled cells can provide valuable information about cellular behavior in the microenvironment, migration and contribution...
Αλέξανδρος Γ. Σφακιανάκης
1h
The erector spinae plane block for effective analgesia after lung lobectomy: Three cases report Rationale:...
The erector spinae plane block for effective analgesia after lung lobectomy: Three cases reportRationale: The thoracic epidural block and thoracic paravertebral block are widely used techniques for multimodal analgesia after thoracic surgery. However, they have several adverse effects, and are not technically easy. Recently, the erector spinae plane block (ESPB), an injected local anesthetic deep to the erector spinae muscle, is a relatively simple and safe technique. Patient concerns: Three patients...
Αλέξανδρος Γ. Σφακιανάκης
1h
Association of CTLA-4 tagging polymorphisms and haplotypes with hepatocellular carcinoma risk: A case-control...
Association of CTLA-4 tagging polymorphisms and haplotypes with hepatocellular carcinoma risk: A case-control studyIt has been proposed that cytotoxic T-lymphocyte antigen 4 (CTLA-4) may attenuate the T-cell activation threshold, thereby decreasing the antitumor response and conferring susceptibility to hepatocellular carcinoma (HCC). In the present study, we selected CTLA-4 tagging single nucleotide polymorphisms (SNPs) and explored the relationship between these polymorphisms and susceptibility...
Αλέξανδρος Γ. Σφακιανάκης
1h
Diagnostic accuracy of different computer-aided diagnostic systems for malignant and benign thyroid...
Diagnostic accuracy of different computer-aided diagnostic systems for malignant and benign thyroid nodules classification in ultrasound images: A systematic review and meta-analysis protocolObjective: The aim of this study was to determine the diagnostic accuracy of different computer-aided diagnostic (CAD) systems for thyroid nodules classification. Methods: A systematic search of the literature was conducted from inception until March, 2019 using the PubMed, EMBASE, Web of science, and Cochrane...
Αλέξανδρος Γ. Σφακιανάκης
1h
Autologous hematopoietic stem cell transplantation for human immunodeficiency virus associated gastric...
Autologous hematopoietic stem cell transplantation for human immunodeficiency virus associated gastric Burkitt lymphoma: A case reportRationale: HIV-related lymphoma, especially non-Hodgkin lymphoma, is one of the most common malignant tumors in HIV/acquired immune deficiency syndrome (AIDS) patients. Autologous hematopoietic stem cell transplantation (AHSCT) for the patients with Burkitt lymphoma (BL) is needed to be further explored. Patient concerns: A 57-year-old man was hospitalized with intermittent...
Αλέξανδρος Γ. Σφακιανάκης
1h
Upregulation of microRNA-191 can serve as an independent prognostic marker for poor survival in prostate...
Upregulation of microRNA-191 can serve as an independent prognostic marker for poor survival in prostate cancerMicroRNA-191 (miR-191) has been identified as being upregulated in several types of cancers, and plays the role of oncogene. The expression of miR-191 has been found to be upregulated in prostate cancer tissues as well as cell lines. In this study, we analyzed the correlation of miR-191 expression with clinicopathologic factors and prognosis in prostate cancer. Prostate cancer tissue samples...
Αλέξανδρος Γ. Σφακιανάκης
1h
Correction of labial tubercle defect in repaired bilateral cleft lips using bilateral vermilion musculomucosal...
Correction of labial tubercle defect in repaired bilateral cleft lips using bilateral vermilion musculomucosal sliding flaps: Case seriesRationale: Insignifificant, asymmetrical or lack of labial tubercle often occurs after cleft lip surgery due to improper treatment of vermilion tissue. Especially in the cases of bilateral cleft lip, because of short front lip and insuffificient vermilion tissue, the median vermilion depression often occurs after surgery, forming a "whistling" deformity. The object...
Αλέξανδρος Γ. Σφακιανάκης
1h
Prognostic role of C-reactive protein to albumin ratio in colorectal cancer: A meta analysis Objective:...
Prognostic role of C-reactive protein to albumin ratio in colorectal cancer: A meta analysisObjective: This meta-analysis evaluates the prognosis value of C-reactive protein to albumin ratio (CAR) in colorectal cancer. Methods: Embase, PubMed, and Web of Science were searched. Pooled hazard ratios (HRs) with their corresponding 95% confidence intervals (CIs) were used as effective values. Results: A total of 6 studies with 1942 patients were included in this study. Pooled results revealed that elevated...
Αλέξανδρος Γ. Σφακιανάκης
1h
Diagnostic value of polymerase chain reaction/acid-fast bacilli in conjunction with computed tomography–guided...
Diagnostic value of polymerase chain reaction/acid-fast bacilli in conjunction with computed tomography–guided pleural biopsy in tuberculous pleurisy: A diagnostic accuracy studyPatients with tuberculous pleurisy often remain undiagnosed even after blind thoracentesis and closed pleural biopsy (PB). In this study, we assessed the value of computed tomography (CT)-guided core needle biopsy of pleural lesion and evaluated the diagnostic accuracy of polymerase chain reaction (PCR)/staining for acid-fast...
Αλέξανδρος Γ. Σφακιανάκης
1h
Therapeutic effect of lutein supplement on non-proliferative diabetic retinopathy: A retrospective study,...
Therapeutic effect of lutein supplement on non-proliferative diabetic retinopathy: A retrospective study,This study retrospectively evaluated the effect of lutein supplement (LS) on patients with non-proliferative diabetic retinopathy (NPDR). A total of 72 patients with NPDR were included in this study. All patients received Zeaxanthin during the study period. In addition, 36 patients also received LS and were assigned to the treatment group, while the other 36 patients did not receive LS and were...
Αλέξανδρος Γ. Σφακιανάκης
1h
Cognitive Processing
Floating novel object recognition in adult zebrafish: a pilot studyAbstractThe novel object recognition (NOR) tasks can be used to quantify memory function in zebrafish similarly to rodents. The development of zebrafish learning and memory tests provides a means for testing the effects of pharmacological manipulations of memory. Several authors reported on the successful application of different objects in NOR tests placed either at the bottom of test tanks or submerged into the tank water of zebrafish....
Αλέξανδρος Γ. Σφακιανάκης
1h
Medicine - Vol. 98, No. 29, July 2019 Lippincott Journals eTOC
Therapeutic effect of lutein supplement on non-proliferative diabetic retinopathy: A retrospective studyThis study retrospectively evaluated the effect of lutein supplement (LS) on patients with non-proliferative diabetic retinopathy (NPDR). A total of 72 patients with NPDR were included in this study. All patients received Zeaxanthin during the study period. In addition, 36 patients also received LS and were assigned to the treatment group, while the other 36 patients did not receive LS and were...
Αλέξανδρος Γ. Σφακιανάκης
1h

Global rosacea treatment guidelines and expert consensus points: The differences Juliandri Juliandri...
Global rosacea treatment guidelines and expert consensus points: The differencesJuliandri Juliandri MD Xiaoyan Wang MD Zijing Liu MD Jiawen Zhang MD Yang Xu MD, PhD Chao Yuan MD, PhDFirst published: 26 February 2019 https://doi.org/10.1111/jocd.12903Funding information:Natural National Science Foundation of China (81301394, 81602778); Construction Program of Jiangsu Provincial Clinical Research Center Support System (BL2014084)Read the full textePDFPDFTOOLS SHARESummaryBackgroundRosacea is a...
Αλέξανδρος Γ. Σφακιανάκης
2h
Autologous pure platelet‐rich plasma injections for facial skin rejuvenation: Biometric instrumental...
Autologous pure platelet‐rich plasma injections for facial skin rejuvenation: Biometric instrumental evaluations and patient‐reported outcomes to support antiaging effectsPeter A Everts PhD  Pedro Contreiras Pinto PhD  Leonor Girão MDFirst published: 23 October 2018 https://doi.org/10.1111/jocd.12802 Cited by: 1Read the full textePDFPDFTOOLS SHARESummaryBackgroundDuring skin aging, a degeneration of connective tissue and decrease in hyaluronic acid polymers occur. Since platelet‐rich plasma (PRP)...
Αλέξανδρος Γ. Σφακιανάκης
2h
Efficacy of platelet‐rich plasma in androgenetic alopecia patients Ghazala Butt MD  Ijaz Hussain FCPS ...
Efficacy of platelet‐rich plasma in androgenetic alopecia patientsGhazala Butt MD  Ijaz Hussain FCPS  Fridoon Jawad Ahmed PhD  Mahmood S Choudhery PhDFirst published: 04 November 2018 https://doi.org/10.1111/jocd.12810 Cited by: 1Read the full textePDFPDFTOOLS SHAREAbstractBackgroundAndrogenetic alopecia (AGA), a patterned hair loss in both males and females, is a commonly occurring disease worldwide. Conventionally, no curative or satisfactory treatment is available for this condition. Therefore,...
Αλέξανδρος Γ. Σφακιανάκης
2h
Biostimulatory effects of polydioxanone, poly‐d, l lactic acid, and polycaprolactone fillers in mouse...
Biostimulatory effects of polydioxanone, poly‐d, l lactic acid, and polycaprolactone fillers in mouse modelTae‐Rin Kwon PhD  Sung Won Han MS  In Kwon Yeo MD  Jong Hwan Kim MS  Jae Min Kim MD  Ji‐Yeon Hong MD  Byung‐Chul Lee MS  Sung‐Eun Lee MS  Ho Sang Moon PhD … See all authorsFirst published: 15 April 2019 https://doi.org/10.1111/jocd.12950Kwon and Han are contributed equally to this study.Read the full textePDFPDFTOOLS SHARESummaryBackgroundNumerous fillers are increasingly used for augmentation...
Αλέξανδρος Γ. Σφακιανάκης
2h
Treatment of alopecia areata with nonablative fractional laser combined with topical minoxidil Wuyuntana...
Treatment of alopecia areata with nonablative fractional laser combined with topical minoxidilWuyuntana Wang MM  Gegentana MM  Tonglaga MD  Bagenna MD  Yuanhong Li MD, PhDFirst published: 06 June 2019 https://doi.org/10.1111/jocd.12883Read the full textePDFPDFTOOLS SHARESummaryBackgroundAlopecia areata (AA) is a relatively common dermatosis with the sudden burst of hair loss on the scalp and other hair‐bearing regions. However, because of high relapse and side effects, no satisfactory therapy has...
Αλέξανδρος Γ. Σφακιανάκης
2h
Injectable profiloplasty: Forehead, nose, lips, and chin filler treatment Dario Bertossi MD  Luca Lanaro...
Injectable profiloplasty: Forehead, nose, lips, and chin filler treatmentDario Bertossi MD  Luca Lanaro MD  Irene Dell'Acqua MD  Massimo Albanese MD  Luciano Malchiodi MD  Pier Francesco Nocini MDFirst published: 15 November 2018 https://doi.org/10.1111/jocd.12792 Cited by: 1Funding information:English review assistance was provided to the authors by ClearView Medical Communications, LLC and funded by Allergan SpA SpA at the request of the investigator. All authors met the ICMJE authorship criteria....
Αλέξανδρος Γ. Σφακιανάκης
2h
Molecular Medicine - Volume:44 Number: Spandidos Publications
O-GlcNAcylation in immunity and inflammation: An intricate system (Review)Yu Li, Mingzheng Xie, Lili Men, Jianling DuView Abstract ❯The association of female and male infertility with telomere length (Review)Eleni Vasilopoulos, Persefoni Fragkiadaki, Charikleia Kalliora, Domniki Fragou, Anca Oana Docea, Elena Vakonaki, Dimitris Tsoukalas, Daniela Calina, Ana Maria Buga, George Georgiadis, Charalampos Mamoulakis, Antonios Makrigiannakis, Demetrios A. Spandidos, Aristidis TsatsakisView Abstract ❯Screening...
Αλέξανδρος Γ. Σφακιανάκης
2h
Herbal alternatives in androgenetic alopecia : Saw palmetto (Serenoa repens), Green tea (Camellia sinensis), Pumpkin seed (Curcurbita pepo), Rosemary (Rosmarinus officinalis), Grape seed (Vitis vinifera), and Licorice (Glycyrrhiza glabra)
REVIEW ARTICLEAn overview of herbal alternatives in androgenetic alopeciaMaria Yusuf Dhariwala M. PharmPadmini Ravikumar M. Pharmhttps://doi.org/10.1111/jocd.12930SummaryThe second most common alopecia—Androgenetic alopecia (AGA)—occurs due to hormonal imbalance. Dihydrotestosterone (DHT) an androgenic hormone is a sex steroid, produced in the gonads. The target sites of DHT are similar to that of testosterone, and it attaches easily remaining bound for 53 minutes as compared to 35 minutes of testosterone....
Αλέξανδρος Γ. Σφακιανάκης
2h
Cosmetic Dermatology
REVIEW ARTICLESGlobal rosacea treatment guidelines and expert consensus points: The differencesJuliandri Juliandri MD  Xiaoyan Wang MD  Zijing Liu MD  Jiawen Zhang MD  Yang Xu MD, PhDChao Yuan MD, PhDPages: 960-965  First Published: 26 February 2019Abstract  Full text  PDF  ReferencesRequest permissionsAn overview of herbal alternatives in androgenetic alopeciaMaria Yusuf Dhariwala M. Pharm  Padmini Ravikumar M. PharmPages: 966-975  First Published: 13 April 2019Abstract  Full text  PDF  ReferencesRequest...
Αλέξανδρος Γ. Σφακιανάκης
2h
Seasonal Minimum and Maximum Solar Ultraviolet Exposure Measurements of Classroom Teachers Residing...
Seasonal Minimum and Maximum Solar Ultraviolet Exposure Measurements of Classroom Teachers Residing in Tropical North Queensland, Australia,Nathan J. Downs Damien P. Igoe Alfio V. Parisi Olivia Taylor Shari L. LazzaroniAlex Rawlings Daniel R. Garzón‐Chavez Simone L. HarrisonPages: 1083-1093 First Published: 08 January 2019Personal erythemally effective exposure of classroom teachers in tropical Townsville (19.3°S) was measured to establish seasonal extremes in exposure behavior. Mean daily personal...
Αλέξανδρος Γ. Σφακιανάκης
2h
Photochemistry and Photobiology Volume 95, Issue 4Pages: 909-1093 July/August 2019 Issue Information...
Photochemistry and PhotobiologyVolume 95, Issue 4Pages: 909-1093July/August 2019Issue InformationIssue InformationPages: 909-910 | First Published: 19 July 2019Research ArticlesPhotostability of Terbinafine Under UVA Irradiation: The Effect of UV AbsorbersAgata Kryczyk‐Poprawa, Paweł Żmudzki, Paulina Koczurkiewicz, Elżbieta Pękala, Urszula HubickaPages: 911-923 | First Published: 22 December 2018In‐depth investigation of the photostability of terbinafine was conducted, taking into account the presence...
Αλέξανδρος Γ. Σφακιανάκης
2h
Photo‐Modification of Melanin by a Mid‐infrared Free‐electron Laser,Takayasu Kawasaki, Aomi Sato, Yuki...
Photo‐Modification of Melanin by a Mid‐infrared Free‐electron Laser,Takayasu Kawasaki, Aomi Sato, Yuki Tominaga, You Suzuki, Takahiro Oyama, Makoto Tadokoro, Koichi Tsukiyama, Kiyoshi Nokihara, Heishun ZenPages: 946-950 | First Published: 05 January 2019 We applied a free‐electron laser tuned to mid‐infrared wavelength (5.8 μm) to irradiate melanin. The melanin powder was dispersed by the pulse irradiation with power energy of 500 mJ cm−2, and the minimum pulse number for damage to the morphology...
Αλέξανδρος Γ. Σφακιανάκης
2h
NLOphoric Triphenylamine Derived Donor‐π‐Acceptor‐π‐Donor Based Colorants: Synthesis, Spectroscopic,...
NLOphoric Triphenylamine Derived Donor‐π‐Acceptor‐π‐Donor Based Colorants: Synthesis, Spectroscopic, Density Functional Theory and Z‐scan Studies,Manish M. Raikwar, Elizabeth Mathew, Manu Varghese, Issac H. Joe, Sekar Nagaiyan NethiPages: 931-945 | First Published: 28 January 2019 Three dyes (5a‐c) with D‐π‐A‐π‐D structural motif were synthesized and investigated for their photophysical and nonlinear optical behavior. The photophysical behavior of 5a‐c were affected by the polarity of the medium...
Αλέξανδρος Γ. Σφακιανάκης
2h
Efficient Photooxidation of Aryl(hetaryl)pyrazolines by Benzoquinone,Valery F. Traven, Ivan V. Ivanov, Sergei...
Efficient Photooxidation of Aryl(hetaryl)pyrazolines by Benzoquinone,Valery F. Traven, Ivan V. Ivanov, Sergei M. Dolotov, Artem N. Semakin, Dmitriy A. Cheptsov, Zarina Z. MamirgovaPages: 924-930 | First Published: 06 January 2019 Photooxidation of aryl(hetaryl)pyrazolines in the presence of benzoquinone in organic solvents undergoes at high rate and provides the corresponding pyrazoles in a good yields. The effects of the solvent, pyrazoline structure and oxygen provide definite information on the...
Αλέξανδρος Γ. Σφακιανάκης
2h
Photostability of Terbinafine Under UVA Irradiation: The Effect of UV Absorbers,Agata Kryczyk‐Poprawa, Paweł...
Photostability of Terbinafine Under UVA Irradiation: The Effect of UV Absorbers,Agata Kryczyk‐Poprawa, Paweł Żmudzki, Paulina Koczurkiewicz, Elżbieta Pękala, Urszula HubickaPages: 911-923 | First Published: 22 December 2018In‐depth investigation of the photostability of terbinafine was conducted, taking into account the presence of UV absorbers such as TiO2, ZnO, avobenzone, 3‐(4‐methylbenzylidene)camphor, octocrylene, benzophenone‐1 and benzophenone‐2. The photocatalytic degradation of terbinafine...
Αλέξανδρος Γ. Σφακιανάκης
2h
19th Internarional Symposium of ISTU 5th European Symposium of EUFUS Barcelona 2019 | 13th - 15th June ABSTRACT BOOK
11:31(Unknown title) Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182, 11:19(Unknown title) Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182, 11:10(Unknown title) Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,11:05(Unknown title) Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182, 11:01(Unknown...
Αλέξανδρος Γ. Σφακιανάκης
1d

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