Τρίτη 8 Σεπτεμβρίου 2020

Medicine by Alexandros G. Sfakianakis


  •   AntibodiesAntibodies, Vol. 9, Pages 46: Investig...
  •    Royal Society of Chemistry (Great Britain) Soci...
  • Novel therapeutic strategies for treating Pseudomo...
  • Aberrantly expressed lncRNAs and mRNAs after botul...
  • Transcriptomic Analysis of Peripheral Blood Mononu...
  • Major Durable Response of Pembrolizumab in Chemoth...
  • Complete Clinical Response in Stage IVB Endometrio...
  • Primary Undifferentiated Pericardial Sarcoma after...
  • "Suprascapular canal": Anatomical and topographica...
  • Meranzin hydrate elicits antidepressant effects an...
  • Experimental autoimmune encephalopathy (EAE)-induc...
  • IL-10 production by ILC2s requires Blimp-1 and cMa...
  • Chest Computed Tomography Findings in Asymptomatic...
  • Inhaled Molgramostim Therapy in Autoimmune Pulmona...
  • Efficacy of oral rosuvastatin intervention on HDL ...
  • Non-glucose risk factors in the pathogenesis of di...
  • Although cow's milk is rich in calcium, it does no...
  • Guidelines Suggesting Children Avoid Plant-Based M...
  • Novel basophil activation test in diagnosis of pov...
  • Challenges in Skin Testing for Progestogen Hyperse...
  • combining OCT with autofluorescence imaging for id...
  •  PSA detection using label free graphene FET with ...
  •  RNA polymerases in strict endosymbiont bacteria w...
  •    Biomedicine & PharmacotherapyThe impact of quet...
  •    Acta Cirurgica BrasileiraThe effect of probioti...
  •    Nature Communications - current - nature.com sc...
  •    American Society for Stereotactic and Functiona...
  •    American Journal of OtolaryngologyThe role of e...
  •    Journal of Neurosurgical Anesthesiology - Curre...
  •    Clinical ImagingDevelopment of a dual-energy sp...
  •    Clinical Cancer Research Online First ArticlesE...
  •   BioMed Research InternationalDevelopment of Auto...
  •    NanomaterialsNanomaterials, Vol. 10, Pages 1764...
  •   MoleculesMolecules, Vol. 25, Pages 4091: Product...
  •    International Journal of Molecular SciencesIJMS...
  •    International Journal of Environmental Research...
  •   CellsCells, Vol. 9, Pages 2044: Decoding IL-23 S...
  •   CancersCancers, Vol. 12, Pages 2548: Cytochrome ...
  •   AntibioticsAntibiotics, Vol. 9, Pages 584: Micro...

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    Novel therapeutic strategies for treating Pseudomonas aeruginosa infection.
    Novel therapeutic strategies for treating Pseudomonas aeruginosa infection.: ABSTRACTIntroductionPersistent infections caused by the superbug Pseudomonas aeruginosa and its resistance to multiple antimicrobial agents are huge threats to patients with cystic fibrosis as well as those with compromised immune systems. Multidrug-resistant P. aeruginosa has posed a major challenge to conventional antibiotics and therapeutic approaches, which show limited efficacy and cause serious side effects. The public...
    OtoRhinoLaryngolgy News
    10:36
    Aberrantly expressed lncRNAs and mRNAs after botulinum toxin type A inhibiting salivary secretion
    Aberrantly expressed lncRNAs and mRNAs after botulinum toxin type A inhibiting salivary secretion: AbstractObjectiveIn this study, we sought to determine the expression profiles of long noncoding RNAs (lncRNAs) and messenger RNAs (mRNAs) and construct functional networks to analyze their potential roles following botulinum toxin type A (BTXA)‐mediated inhibition of salivary secretion.MethodsThe submandibular gland of rats in the BTXA and control groups were injected with BTXA and saline, respectively....
    OtoRhinoLaryngolgy News
    10:33
    Transcriptomic Analysis of Peripheral Blood Mononuclear Cells in HNSCC Patients
    Transcriptomic Analysis of Peripheral Blood Mononuclear Cells in HNSCC Patients: AbstractObjectivesTo investigate the gene expression profile of peripheral blood mononuclear cells (PBMCs) from head and neck squamous cell carcinoma (HNSCC), including oral cancer (OC) and oropharyngeal cancer (OPC) patients, and compare them with healthy controls (HC).Materials and MethodsTranscriptomic analysis of PBMCs was performed by RNA‐sequencing. The upregulated candidate genes were selected for validation by...
    OtoRhinoLaryngolgy News
    10:31
    Major Durable Response of Pembrolizumab in Chemotherapy Refractory Small Cell Bladder Cancer: A Case Report
    Major Durable Response of Pembrolizumab in Chemotherapy Refractory Small Cell Bladder Cancer: A Case Report: Small cell carcinoma of the urinary bladder is a rare subtype (incidence of 1–9/1,000,000), characterized by an aggressive behavior with early metastasis and poor prognosis. Chemotherapy, radiation, and surgery are the usual treatment options, but to date, no accepted standard treatment exists. Since small cell bladder cancer shares similar clinicopathological features with small cell lung...
    OtoRhinoLaryngolgy News
    10:30
    Complete Clinical Response in Stage IVB Endometrioid Endometrial Carcinoma after First-Line Pembrolizumab Therapy: Report of a Case with Isolated Loss of PMS2 Protein
    Complete Clinical Response in Stage IVB Endometrioid Endometrial Carcinoma after First-Line Pembrolizumab Therapy: Report of a Case with Isolated Loss of PMS2 Protein: Endometrial cancer is the only gynecological cancer that is rising in incidence and associated mortality worldwide. Although most cases are diagnosed as early stage disease, with chances of cure after primary surgical treatment, those with advanced or metastatic disease have a poor prognosis because of the quality of treatment options...
    OtoRhinoLaryngolgy News
    10:30
    Primary Undifferentiated Pericardial Sarcoma after Radiоtherapy for Hodgkin Lymphoma
    Primary Undifferentiated Pericardial Sarcoma after Radiоtherapy for Hodgkin Lymphoma: Various types of sarcomas arise as a result of postradiation chronic fibrous pericarditis. A primary undifferentiated spindle cell pericardial sarcoma is a rare type of sarcoma after radiotherapy. The risk of sarcoma increases with time after treatment of cancer. A 55-year-old woman underwent successful radiation and chemotherapy for Hodgkin lymphoma 20 years ago. She was hospitalized with typical manifestations...
    OtoRhinoLaryngolgy News
    10:29
    "Suprascapular canal": Anatomical and topographical description and its clinical implication in entrapment syndrome
    "Suprascapular canal": Anatomical and topographical description and its clinical implication in entrapment syndrome: Publication date: Available online 6 September 2020Source: Annals of Anatomy - Anatomischer AnzeigerAuthor(s): Azzat Al-Redouan, Keiv Holding, David Kachlik
    OtoRhinoLaryngolgy News
    10:28
    Meranzin hydrate elicits antidepressant effects and restores reward circuitry
    Meranzin hydrate elicits antidepressant effects and restores reward circuitry: Publication date: Available online 6 September 2020Source: Behavioural Brain ResearchAuthor(s): XiangFei Liu, JiaLing Zhou, Tian Zhang, Ken Chen, Min Xu, Lei Wu, Jin Liu, YunKe Huang, BinBin Nie, Xu Shen, Ping Ren, Xi Huanga
    OtoRhinoLaryngolgy News
    10:27
    Experimental autoimmune encephalopathy (EAE)-induced hippocampal neuroinflammation and memory deficits are prevented with the non-opioid TLR2/TLR4 antagonist (+)-naltrexone
    Experimental autoimmune encephalopathy (EAE)-induced hippocampal neuroinflammation and memory deficits are prevented with the non-opioid TLR2/TLR4 antagonist (+)-naltrexone: Publication date: Available online 6 September 2020Source: Behavioural Brain ResearchAuthor(s): Andrew J. Kwilasz, Laurel S. Todd, Julissa C. Duran-Malle, Anouk E.W. Schrama, Eric H. Mitten, Tracey A. Larson, Madison A. Clements, Kevin M. Harris, Scott T. Litwiler, Xiaohui Wang, Anne-Marie Van Dam, Steven F. Maier, Kenner C....
    OtoRhinoLaryngolgy News
    10:26
    IL-10 production by ILC2s requires Blimp-1 and cMaf, modulates cellular metabolism and ameliorates airway hyperreactivity
    IL-10 production by ILC2s requires Blimp-1 and cMaf, modulates cellular metabolism and ameliorates airway hyperreactivity: Publication date: Available online 6 September 2020Source: Journal of Allergy and Clinical ImmunologyAuthor(s): Emily Howard, Gavin Lewis, Lauriane Galle-Treger, Benjamin P. Hurrell, Doumet Georges Helou, Pedram Shafiei-Jahani, Jacob Painter, German Aleman Muench, Pejman Soroosh, Omid Akbari
    OtoRhinoLaryngolgy News
    10:25
    Chest Computed Tomography Findings in Asymptomatic Patients with COVID-19..................., all patients (100%) had ground-glass opacity (GGO) on chest CT. Further, the GGO lesions were predominantly distributed peripherally and posteriorly in all patients. In 9 (90%) patients, the GGO lesions were combined with reticular opacity. Air bronchogram due to bronchiolectasis surrounded by GGO was observed in 8 patients (80%). Additionally, the lung lesions were dominant on the right side in all patients.
    Chest Computed Tomography Findings in Asymptomatic Patients with COVID-19: Background: Little is known about the damage to the respiratory system in asymptomatic patients with coronavirus disease (COVID-19). Objective: Herein, we evaluate the findings of chest computed tomography (CT) and radiography in patients with COVID-19 who were asymptomatic. Methods: We retrospectively investigated patients with a confirmed diagnosis of COVID-19 but who did not show any symptoms. Among the 139 patients with...
    OtoRhinoLaryngolgy News
    10:25
    Inhaled Molgramostim Therapy in Autoimmune Pulmonary Alveolar Proteinosis
    Inhaled Molgramostim Therapy in Autoimmune Pulmonary Alveolar Proteinosis: Autoimmune pulmonary alveolar proteinosis (aPAP) is a disease characterized by alveolar filling that leads to progressive accumulation of surfactant in alveoli, hypoxemia, and in some patients, the development of serious infections or pulmonary fibrosis. Although PAP can be caused by multiple…
    OtoRhinoLaryngolgy News
    10:22
    Efficacy of oral rosuvastatin intervention on HDL and its associated proteins in men with type 2 diabetes mellitus
    Efficacy of oral rosuvastatin intervention on HDL and its associated proteins in men with type 2 diabetes mellitus: AbstractPurposeHigh-density lipoprotein (HDL) undergoes structural and functional modification in patients with type 2 diabetes mellitus (T2DM). There are limited data on effect of rosuvastatin on HDL-associated proteins and the antiatherogenic effects of rosuvastatin. The present study intended to study the efficacy of rosuvastatin intervention on HDL-associated proteins and its other...
    OtoRhinoLaryngolgy News
    10:22
    Non-glucose risk factors in the pathogenesis of diabetic peripheral neuropathy
    Non-glucose risk factors in the pathogenesis of diabetic peripheral neuropathy: AbstractIn this review, we consider the diverse risk factors in diabetes patients beyond hyperglycemia that are being recognized as contributors to diabetic peripheral neuropathy (DPN). Interest in such alternative mechanisms has been encouraged by the recognition that neuropathy occurs in subjects with metabolic syndrome and pre-diabetes and by the reporting of several large clinical studies that failed to show reduced...
    OtoRhinoLaryngolgy News
    10:21
    Although cow's milk is rich in calcium, it does not appear to clearly reduce fractures, but consumption carries risks including: a potential association with type 1 diabetes mellitus onset; anemia in toddlers; lactose intolerance; cow's milk protein allergy; and infantile colic. ........................................Guidelines Suggesting Children Avoid Plant-Based Milks: A Closer Examination
    Guidelines Suggesting Children Avoid Plant-Based Milks: A Closer Examination: AbstractRecent Healthy Drinks, Healthy Kids (HDHK) guidelines state children between 12 and 24 months need to be consuming 2–3 cups a day of whole fat cow's milk, and less of all other beverages except water. Guidelines explicitly state plant-based milks should be avoided (with the exception of soy milk). We agree that in the first 12 months the optimal food for childhood growth is breast milk, with formula used where needed....
    OtoRhinoLaryngolgy News
    10:20
    Guidelines Suggesting Children Avoid Plant-Based Milks: A Closer Examination
    Guidelines Suggesting Children Avoid Plant-Based Milks: A Closer Examination: AbstractRecent Healthy Drinks, Healthy Kids (HDHK) guidelines state children between 12 and 24 months need to be consuming 2–3 cups a day of whole fat cow's milk, and less of all other beverages except water. Guidelines explicitly state plant-based milks should be avoided (with the exception of soy milk). We agree that in the first 12 months the optimal food for childhood growth is breast milk, with formula used where needed....
    OtoRhinoLaryngolgy News
    10:19
    Novel basophil activation test in diagnosis of povidone anaphylaxis
    Novel basophil activation test in diagnosis of povidone anaphylaxis: Medications generally contain two components: the active ingredient – intended to produce the desired therapeutic effect, and excipients – inactive ingredients added for purposes such as improving absorption and product stability. Although considered inert, excipients may represent occult allergens capable of causing allergic reactions. To date, thirty-eight excipients have been described to cause symptoms, with an increasing number...
    OtoRhinoLaryngolgy News
    10:18
    Challenges in Skin Testing for Progestogen Hypersensitivity
    Challenges in Skin Testing for Progestogen Hypersensitivity: Progestogen hypersensitivity (PH) is an increasingly recognized heterogenous clinical entity that presents as hypersensitivity symptoms associated with the progesterone surge during the luteal phase of the menstrual cycle or following exposure to exogenous progestins1. Diagnosis requires a careful clinical history and assessment to evaluate other potential triggers, and at minimum, compatible symptoms associated with exposure to endogenous...
    OtoRhinoLaryngolgy News
    10:18
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     PSA detection using label free graphene FET with coplanar electrodes based microfluidic point of care diagnostic devicePublication date: 15 January 2021Source: Talanta, Volume 222Author(s): Naresh Mandal, Victor Pakira, Nirmalya Samanta, Naren Das, Suman Chakraborty, Bidhan Pramanick, Chirasree RoyChaudhuriScienceDirect Publication: TalantaMon Sep 07, 2020 13:50Synthesizing of a nanocomposite based on the formation of silver nanoparticles on fumed silica to develop an electrochemical sensor for...
    OtoRhinoLaryngolgy News
    10:16
    combining OCT with autofluorescence imaging for identifying neck tissues......................Multimodal imaging with integrated auto-fluorescence and optical coherence tomography for identification of neck tissues
    Multimodal imaging with integrated auto-fluorescence and optical coherence tomography for identification of neck tissues: AbstractWe report a multimodal optical system by combining OCT with autofluorescence imaging for identifying neck tissues, which can use the advantages of large field of view and high sensitivity for identifying parathyroid glands of fluorescence imaging, and high-resolution structural imaging of OCT to confirm them and identify lymph nodes and metastatic lymph nodes at the same...
    OtoRhinoLaryngolgy News
    10:16
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      Biomedicine & PharmacotherapyThe impact of quetiapine on the brain lipidome in a cuprizone-induced mouse model of schizophreniaPublication date: November 2020Source: Biomedicine & Pharmacotherapy, Volume 131Author(s): Cui-hong Zhou, Shan-shan Xue, Fen Xue, Ling Liu, Jun-chang Liu, Quan-rui Ma, Jun-hui Qin, Qing-rong Tan, Hua-ning Wang, Zheng-wu PengBiomedicine & PharmacotherapyMon Sep 07, 2020 14:04Effects of galloflavin and ellagic acid on sirtuin 6 and its anti-tumorigenic activitiesPublication...
    OtoRhinoLaryngolgy News
    10:16
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     RNA polymerases in strict endosymbiont bacteria with extreme genome reduction show distinct erosions that could result in limited and differential promoters recognition. [NEW RESULTS]Strict endosymbiont bacteria with high degree of genome reduction retain smaller proteins and, in certain cases, lack complete functional domains compared to their free-living counterparts. Until now, the mechanisms underlying these genetic reductions are not well understood. However, it is thought that, in order to...
    OtoRhinoLaryngolgy News
    10:16
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      Acta Cirurgica BrasileiraThe effect of probiotics on ıntestinal motility in an experimental short bowel modelAbstract Purpose To investigate the effect of probiotics on spontaneous contractions of smooth muscle isolated from jejunum and ileum of rat model. Methods Four rat groups were created (n=8, in each) including control (Group 1), control+probiotic (Group 2), short bowel (Group 3), and short bowel+probiotic (Group 4). Groups 1 and 2 underwent sham operation, Groups 3 and 4 underwent massive...
    OtoRhinoLaryngolgy News
    10:16
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      Nature Communications - current - nature.com science feedsEngineered systems of inducible anti-repressors for the next generation of biological programmingNature Communications, Published online: 07 September 2020; doi:10.1038/s41467-020-18302-1Transcriptional anti-repressors have been largely absent in the design of regulated genetic circuits. Here, the authors present a workflow of the engineering of non-natural anti-reperssors that can be built into NOT oriented logic gates.Nature Communications...
    OtoRhinoLaryngolgy News
    10:16
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      American Society for Stereotactic and Functional NeurosurgeryClinical Outcome and Intraoperative Neurophysiology of the Lance-Adams Syndrome Treated with Bilateral Deep Brain Stimulation of the Globus Pallidus Internus: A Case Report and Review of the LiteratureBackground: The Lance-Adams syndrome (LAS) is a myoclonus syndrome caused by hypoxic-ischemic encephalopathy. LAS cases could be refractory to first-line medications, and the neuronal mechanism underlying LAS pathology remains unknown. Objectives:...
    OtoRhinoLaryngolgy News
    10:16
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      American Journal of OtolaryngologyThe role of endoscopic sphenopalatine artery ligation in the management of persistent epistaxis — A 15-year single-center experiencePublication date: Available online 6 September 2020Source: American Journal of OtolaryngologyAuthor(s): Idit Tessler, Meir Warman, Sharav Shimrit, Hadar Batito, Doron Halperin, Oded CohenAmerican Journal of OtolaryngologyMon Sep 07, 2020 13:14Mark above section as read Auris Nasus LarynxChronic spontaneous urticaria and angioedema...
    OtoRhinoLaryngolgy News
    10:16
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      Journal of Neurosurgical Anesthesiology - Current IssueA Case of Malignant Cerebral Edema Following Removal of Infected Autologous Cranioplasty FlapNo abstract availableJournal of Neurosurgical Anesthesiology - Current Issue02:40Neurocritical Care in Resource-limited SettingsNo abstract availableJournal of Neurosurgical Anesthesiology - Current Issue02:40Noninvasive Intracranial Pressure Estimation With Transcranial Doppler: A Prospective Observational StudyBackground: Transcranial Doppler (TCD)...
    OtoRhinoLaryngolgy News
    10:16
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      Clinical ImagingDevelopment of a dual-energy spectral CT based nomogram for the preoperative discrimination of mutated and wild-type <em>KRAS</em> in patients with colorectal cancerPublication date: Available online 6 September 2020Source: Clinical ImagingAuthor(s): Yuntai Cao, Guojin Zhang, Haihua Bao, Shenghui Zhang, Jing Zhang, Zhiyong Zhao, Wenjuan Zhang, Weixia Li, Xiaohong Yan, Junlin ZhouClinical ImagingMon Sep 07, 2020 16:41Mark above section as read European Journal of Nuclear...
    OtoRhinoLaryngolgy News
    10:16
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      Clinical Cancer Research Online First ArticlesEffects of acute and chronic graft-versus-myelodysplastic syndrome on long-term outcomes following allogeneic hematopoietic cell transplantationPurpose: Potent graft-versus-tumor (GVT) effects associated with graft-versus-host disease (GVHD) might be dependent on hematological disease type and status. However, the data regarding the impact of GVHD on transplant outcomes for patients with myelodysplastic syndrome (MDS) are limited. Patients and Methods:...
    OtoRhinoLaryngolgy News
    10:16
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      BioMed Research InternationalDevelopment of Autophagy Signature-Based Prognostic Nomogram for Refined Glioma Survival PrognosticationThe current glioma classification could be optimized to cover such a separate and individualized prognosis ranging from a few months to over ten years. Considering its highly conserved role and potential in therapies, autophagy might be a promising element to be incorporated as a refinement for improved survival prognostication. The expression and RNA-seq data of...
    OtoRhinoLaryngolgy News
    10:16
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      NanomaterialsNanomaterials, Vol. 10, Pages 1764: Developments in the Application of Nanomaterials for Water Treatment and Their Impact on the EnvironmentNanomaterials, Vol. 10, Pages 1764: Developments in the Application of Nanomaterials for Water Treatment and Their Impact on the Environment Nanomaterials doi: 10.3390/nano10091764 Authors: Haleema Saleem Syed Javaid Zaidi Nanotechnology is an uppermost priority area of research in several nations presently because of its enormous capability and...
    OtoRhinoLaryngolgy News
    10:16
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      MoleculesMolecules, Vol. 25, Pages 4091: Production and Characterization of Antioxidative Hydrolysates and Peptides from Corn Gluten Meal Using Papain, Ficin, and BromelainMolecules, Vol. 25, Pages 4091: Production and Characterization of Antioxidative Hydrolysates and Peptides from Corn Gluten Meal Using Papain, Ficin, and Bromelain Molecules doi: 10.3390/molecules25184091 Authors: Ruijia Hu Gengjun Chen Yonghui Li There has been a growing interest in developing natural antioxidants with high...
    OtoRhinoLaryngolgy News
    10:16
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      International Journal of Molecular SciencesIJMS, Vol. 21, Pages 6528: Multiple Known Mechanisms and a Possible Role of an Enhanced Immune System in Bt-Resistance in a Field Population of the Bollworm, Helicoverpa zea: Differences in Gene Expression with RNAseqIJMS, Vol. 21, Pages 6528: Multiple Known Mechanisms and a Possible Role of an Enhanced Immune System in Bt-Resistance in a Field Population of the Bollworm, Helicoverpa zea: Differences in Gene Expression with RNAseq International Journal...
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    10:16
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      International Journal of Environmental Research and Public HealthIJERPH, Vol. 17, Pages 6506: Forest Volatile Organic Compounds and Their Effects on Human Health: A State-of-the-Art ReviewIJERPH, Vol. 17, Pages 6506: Forest Volatile Organic Compounds and Their Effects on Human Health: A State-of-the-Art Review International Journal of Environmental Research and Public Health doi: 10.3390/ijerph17186506 Authors: Michele Antonelli Davide Donelli Grazia Barbieri Marco Valussi Valentina Maggini Fabio...
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    10:16
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      CellsCells, Vol. 9, Pages 2044: Decoding IL-23 Signaling Cascade for New Therapeutic OpportunitiesCells, Vol. 9, Pages 2044: Decoding IL-23 Signaling Cascade for New Therapeutic Opportunities Cells doi: 10.3390/cells9092044 Authors: Gloria Pastor-Fernández Isabel R. Mariblanca María N. Navarro The interleukin 23 (IL-23) is a key pro-inflammatory cytokine in the development of chronic inflammatory diseases, such as psoriasis, inflammatory bowel diseases, multiple sclerosis, or rheumatoid arthritis....
    OtoRhinoLaryngolgy News
    10:16
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      CancersCancers, Vol. 12, Pages 2548: Cytochrome C Oxidase Subunit 4 (COX4): A Potential Therapeutic Target for the Treatment of Medullary Thyroid CancerCancers, Vol. 12, Pages 2548: Cytochrome C Oxidase Subunit 4 (COX4): A Potential Therapeutic Target for the Treatment of Medullary Thyroid Cancer Cancers doi: 10.3390/cancers12092548 Authors: Athanasios Bikas Kirk Jensen Aneeta Patel John Costello Sarah M. Reynolds Maria Cecilia Mendonca-Torres Shilpa Thakur Joanna Klubo-Gwiezdzinska Dorina Ylli...
    OtoRhinoLaryngolgy News
    10:16
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      AntibioticsAntibiotics, Vol. 9, Pages 584: Microbes in Our Food, an Ongoing Problem with New SolutionsAntibiotics, Vol. 9, Pages 584: Microbes in Our Food, an Ongoing Problem with New Solutions Antibiotics doi: 10.3390/antibiotics9090584 Authors: Birgit M. Prüβ Despite an increasing number of techniques that are designed to mitigate microbial contamination of food and the resulting food borne disease outbreaks, the United States and many other countries across the world continue to experience impressive...
    OtoRhinoLaryngolgy News
    10:16

    Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,00306932607174,alsfakia@gmail.com,
      International Journal of Environmental Research and Public HealthIJERPH, Vol. 17, Pages 6493: The Light and Shadow of Rapid Serological Tests for SARS-CoV-2 Infection: Results from a Study in a Large Emergency DepartmentIJERPH, Vol. 17, Pages 6493: The Light and Shadow of Rapid Serological Tests for SARS-CoV-2 Infection: Results from a Study in a Large Emergency Department International Journal of Environmental Research and Public Health doi: 10.3390/ijerph17186493 Authors: Daniela Loconsole Francesca...
    Medicine by Alexandros G. Sfakianakis
    Mon Sep 07, 2020 08:17
    Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,00306932607174,alsfakia@gmail.com,
      Journal of the American Chemical Society: Latest Articles (ACS Publications)[ASAP] Next-Generation Total Synthesis of VancomycinJournal of the American Chemical SocietyDOI: 10.1021/jacs.0c07433Journal of the American Chemical Society: Latest Articles (ACS Publications)Fri Sep 04, 2020 07:00[ASAP] Imaging the Thermal Hysteresis of Single Spin-Crossover NanoparticlesJournal of the American Chemical SocietyDOI: 10.1021/jacs.0c05951Journal of the American Chemical Society: Latest Articles (ACS Publications)Fri...
    Medicine by Alexandros G. Sfakianakis
    Mon Sep 07, 2020 08:16
    Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,00306932607174,alsfakia@gmail.com,
      Journal of BiophotonicsThe use of photoacoustic imaging for monitoring vascular disrupting cancer treatmentsAbstract Vascular disrupting agents disrupt tumour vessels, blocking the nutritional and oxygen supply tumours need to thrive. This is achieved by damaging the endothelium lining of blood vessels, resulting in red blood cells (RBCs) entering the tumour parenchyma. RBCs present in the extracellular matrix are exposed to external stressors resulting in biochemical and physiological changes....
    Medicine by Alexandros G. Sfakianakis
    Mon Sep 07, 2020 08:16
    Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,00306932607174,alsfakia@gmail.com,
      CortexIntrinsic functional connectivity of the default mode and cognitive control networks relate to change in behavioral performance over two yearsPublication date: Available online 6 September 2020Source: CortexAuthor(s): Isabella A. Breukelaar, Kristi R. Griffiths, Anthony Harris, Sheryl L. Foster, Leanne M. Williams, Mayuresh S. KorgaonkarCortexSun Sep 06, 2020 21:565-year course of therapy-induced recovery in chronic non-fluent aphasia - Three single cases -Publication date: Available online...
    Medicine by Alexandros G. Sfakianakis
    Mon Sep 07, 2020 08:15
    Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,00306932607174,alsfakia@gmail.com,
     Low‐dose isotretinoin as a therapeutic option for dissecting cellulitisWiley: Dermatologic Therapy: Table of ContentsSat Sep 05, 2020 21:56Non‐inflammatory nodule formation after hyperdiluted Calcium Hydroxyapatite treatment in the neck areaWiley: Dermatologic Therapy: Table of ContentsSat Sep 05, 2020 21:55Methylene blue vs. methyl aminolevulinate photodynamic therapy in the treatment of mild‐to‐moderate toenail onychomycosis: short and medium‐term effectsABSTRACT Photodynamic therapy (PDT) has...
    Medicine by Alexandros G. Sfakianakis
    Mon Sep 07, 2020 08:14
    Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,00306932607174,alsfakia@gmail.com,
     Embryonal tumors of the central nervous system.Related Articles Embryonal tumors of the central nervous system. Curr Opin Oncol. 2020 Sep 02;: Authors: Pagès M, Masliah-Planchon J, Bourdeaut F Abstract PURPOSE OF REVIEW: This review aims to give an update on histopathological, molecular and clinical features of central nervous system (CNS) 'embryonal' tumors. RECENT FINDINGS: The taxonomy of previously called 'CNS primitive neuroectodermal tumor' (CNS PNET) has been deeply modified...Rare CancersSun...
    Medicine by Alexandros G. Sfakianakis
    Mon Sep 07, 2020 08:13
    Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,00306932607174,alsfakia@gmail.com,
     ContentsPublication date: October 2020Source: Clinics in Plastic Surgery, Volume 47, Issue 4Author(s):Plastic SurgeryFri Sep 04, 2020 16:22Unique Techniques or Approaches in Microvascular and Microlymphatic SurgeryPublication date: October 2020Source: Clinics in Plastic Surgery, Volume 47, Issue 4Author(s): Jin Bo Tang, Luis Landín, Pedro C. Cavadas, Alessandro Thione, Jing Chen, Gemma Pons, Jaume MasiàPlastic SurgeryFri Sep 04, 2020 16:22Maximizing the Utility of the Pedicled Anterolateral Thigh...
    Medicine by Alexandros G. Sfakianakis
    Mon Sep 07, 2020 08:12
    Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,00306932607174,alsfakia@gmail.com,
     A minimal yet flexible likelihood framework to assess correlated evolution [NEW RESULTS]An evolutionary process is reflected in the sequence of changes through time of any trait (e.g. morphological, molecular). Yet, a better understanding of evolution would be procured by characterizing correlated evolution, or when two or more evolutionary processes interact. A wide range of parametric methods have previously been proposed to detect correlated evolution but they often require significant computing...
    Medicine by Alexandros G. Sfakianakis
    Mon Sep 07, 2020 08:12
    Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,00306932607174,alsfakia@gmail.com,
     Enantioselective Total Synthesis of (‐)‐Finerenone using Asymmetric Transfer Hydrogenation(‐)‐Finerenone is a nonsteroidal mineralocorticoid receptor antagonist currently in phase III clinical trials for the treatment of chronic kidney disease in type 2 diabetes. It contains an unusual dihydronaphthyridine core. Herein, we report a 6‐step synthesis of (‑)‐Finerenone which features an enantioselective partial transfer hydrogenation of a naphthyridine using a chiral phosphoric acid catalyst with a...
    Medicine by Alexandros G. Sfakianakis
    Mon Sep 07, 2020 08:11
    Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,00306932607174,alsfakia@gmail.com,
      Biomedicine & PharmacotherapyFetuin B overexpression suppresses proliferation, migration, and invasion in prostate cancer by inhibiting the PI3K/AKT signaling pathwayPublication date: November 2020Source: Biomedicine & Pharmacotherapy, Volume 131Author(s): Kai Zhan, Rui Liu, Hang Tong, Shun Gao, Guang Yang, Arman Hossain, Tinghao Li, Weiyang HeBiomedicine & PharmacotherapySat Sep 05, 2020 21:28Metabolic profiling, <em>in vitro</em> bioaccessibility and <em>in vivo</em>...
    Medicine by Alexandros G. Sfakianakis
    Mon Sep 07, 2020 08:10
    Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,00306932607174,alsfakia@gmail.com,
      DysphagiaA Preliminary Investigation of Whether HRCA Signals Can Differentiate Between Swallows from Healthy People and Swallows from People with Neurodegenerative DiseasesAbstract High-resolution cervical auscultation (HRCA) is an emerging method for non-invasively assessing swallowing by using acoustic signals from a contact microphone, vibratory signals from an accelerometer, and advanced signal processing and machine learning techniques. HRCA has differentiated between safe and unsafe swallows,...
    Medicine by Alexandros G. Sfakianakis
    Mon Sep 07, 2020 08:09
    Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,00306932607174,alsfakia@gmail.com,
      Acta Cirurgica BrasileiraPrevention of bone infection after open fracture using a chitosan with ciprofloxacin implant in animal modelAbstract Purpose To evaluate different concentrations of ciprofloxacin to prevent infection after open fracture contaminated with S. aureus in rats using absorbable local delivery system. Methods Fifty-two Wistar rats were assigned to six groups. After 4 weeks, all animals underwent 99mTc-ceftizoxima scintigraphy evaluation, callus formation measurement and histological...
    Medicine by Alexandros G. Sfakianakis
    Mon Sep 07, 2020 08:09
    Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,00306932607174,alsfakia@gmail.com,
      BMC Research NotesPerioperative hemoglobin decrement as an independent risk of poor early graft function in kidney transplantationPerioperative change of hemoglobin concentration (Hb) was associated with acute kidney injury in patients who underwent non-cardiac surgery, but has never been investigated in kidney transplant patients. This ...BMC Research NotesSat Sep 05, 2020 03:00An anti-perfringolysin O monoclonal antibody cross-reactive with streptolysin O protects against streptococcal toxic...
    Medicine by Alexandros G. Sfakianakis
    Mon Sep 07, 2020 08:08
    Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,00306932607174,alsfakia@gmail.com,
     Prevention of brain metastases in human epidermal growth factor receptor 2-positive breast cancer.Related Articles Prevention of brain metastases in human epidermal growth factor receptor 2-positive breast cancer. Curr Opin Oncol. 2020 Sep 02;: Authors: Eberst L, Bailleux C, Bachelot T Abstract PURPOSE: For patients with human epidermal growth factor receptor 2 (HER2)-positive breast cancer, treatments that could prevent or delay occurrence of brain metastases would improve outcome. RECENT FINDINGS:...
    Medicine by Alexandros G. Sfakianakis
    Mon Sep 07, 2020 08:08
    Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,00306932607174,alsfakia@gmail.com,
      pubmed: basal ganglia stroke...Elevated miR-29a Contributes to Axonal Outgrowth and Neurological Recovery After Intracerebral Hemorrhage via Targeting PTEN/PI3K/Akt Pathway.Related Articles Elevated miR-29a Contributes to Axonal Outgrowth and Neurological Recovery After Intracerebral Hemorrhage via Targeting PTEN/PI3K/Akt Pathway. Cell Mol Neurobiol. 2020 Sep 05;: Authors: Zhao M, Gao J, Zhang Y, Jiang X, Tian Y, Zheng X, Wang K, Cui J Abstract Spontaneous intracerebral hemorrhage (ICH) is a clinical...
    Medicine by Alexandros G. Sfakianakis
    Mon Sep 07, 2020 08:07
    Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,00306932607174,alsfakia@gmail.com,
     oral surg oral medOral lesions in patients with SARS-CoV-2 infection: could the oral cavity be a target organ?Related Articles Oral lesions in patients with SARS-CoV-2 infection: could the oral cavity be a target organ? Oral Surg Oral Med Oral Pathol Oral Radiol. 2020 Aug 18;: Authors: Brandão TB, Gueiros LA, Melo TS, Prado-Ribeiro AC, Nesrallah ACFA, Prado GVB, Santos-Silva AR, Migliorati CA Abstract Several viruses transmitted through saliva, such as herpes simplex virus, cytomegalovirus, and...
    Medicine by Alexandros G. Sfakianakis
    Mon Sep 07, 2020 08:06





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      NanomaterialsNanomaterials, Vol. 10, Pages 1741: Dynamics and Applications of Photon-Nanostructured SystemsNanomaterials, Vol. 10, Pages 1741: Dynamics and Applications of Photon-Nanostructured Systems Nanomaterials doi: 10.3390/nano10091741 Authors: Evangelia Sarantopoulou In a speedy and complicated word, only a small number of book readers have the time to dig out the hidden "gemstones" between the text lines [...]Nanomaterials03:00Σήμανση της παραπάνω ενότητας ως αναγνωσμένης BiosensorsBiosensors,...
      The Journal of PhysiologyRebuttal from Francisco J. Alvarez‐LeefmansThe Journal of PhysiologyTue Sep 01, 2020 16:55Neurovascular coupling: sending this signal here, hope you pick it up loud and clearThe Journal of PhysiologyTue Sep 01, 2020 13:30Mark above section as read Journal of Evolutionary BiologyWithin‐population variation in female mating preference affects the opportunity for sexual selection and the evolution of male traits, but things are not as simple as expectedAbstract Females from...
      Journal of Endocrinological InvestigationMesenchymal stem cells-originated exosomal microRNA-152 impairs proliferation, invasion and migration of thyroid carcinoma cells by interacting with DPP4Abstract Background Thyroid carcinoma (THCA) is the most prevalent tumor in the endocrine system with an increasing incidence. Recent studies have underscored the function of microRNAs (miRNAs) in THCA. Nevertheless, knowledge regarding the effects of exosomal miRNAs in THCA is still limited. This report...
      International journal of basic and clinical endocrinologyMeta-analytic evidence for increased low-grade systemic inflammation and oxidative stress in hypothyroid patients. Can levothyroxine replacement therapy mitigate the burden?Abstract Purpose This series of meta-analyses were aimed to elucidate the impact of hypothyroidism on low-grade systemic inflammation and oxidative stress assessed by C-reactive protein (CRP) and malondialdehyde (MDA) respectively; and to evaluate the effect of levothyroxine...
      bioRxiv Subject Collection: Evolutionary BiologyWhen the microbiome defines the host phenotype: selection on vertical transmission in varying environments [NEW RESULTS]The microbiome can contribute to variation in fitness-related traits of their hosts, and thus to host evolution. Hosts are therefore expected to be under selection to control their microbiome, for instance through controlling microbe transmission from parents to offspring. Current models have mostly focused on microbes that either...
     Bench Testing of a Bubble Noninvasive Ventilation Device in an Infant Lung SimulatorBACKGROUND:Infant respiratory distress remains a significant problem worldwide, leading to more than one million neonatal deaths each year. The cost, maintenance, energy, and personnel required to implement ventilators have proven to be a barrier in many resource-limited settings. To address these barriers, a nonelectric bubble noninvasive positive pressure ventilation (NIV) device was developed. This study aims...
     Clinical decision making in small non-functioning VHL-related incidentalomas.Related Articles Clinical decision making in small non-functioning VHL-related incidentalomas. Endocr Connect. 2020 Aug;9(8):834-844 Authors: Därr R, Kater J, Sekula P, Bausch B, Krauss T, Bode C, Walz G, Neumann HP, Zschiedrich S Abstract The optimal treatment strategy for patients with small non-functioning VHL-related incidentalomas is unclear. We searched the Freiburg VHL registry for patients with radiologic evidence...
      Nature Communications - current - nature.com science feedsAccurate quantification of copy-number aberrations and whole-genome duplications in multi-sample tumor sequencing dataNature Communications, Published online: 02 September 2020; doi:10.1038/s41467-020-17967-yThe correct identification of copy-number aberrations (CNAs) in tumours can provide information for diagnosis, prognosis and therapeutic strategies. Here, the authors provide an algorithm, HATCHet, which quantifies CNAs using multiple...
      Clinical Oral Implants ResearchComparison of a polyethylene glycol membrane and a collagen membrane for the treatment of bone dehiscence defects at bone level implants ‐ a prospective, randomized, controlled, multicenter clinical trialAbstract Objectives The aim of the present randomized, controlled clinical multicenter trial was to compare a polyethylenglycol (PEG) and a native collagen membrane (BG) for simultaneous guided bone regeneration (GBR) at bony dehiscence‐type defects around bone level...
      Clinical Neurology and NeurosurgeryTherapeutic anticoagulation for venous thromboembolism after recent brain surgery: evaluating the risk of intracranial hemorrhagePublication date: Available online 1 September 2020Source: Clinical Neurology and NeurosurgeryAuthor(s): José Orlando de Melo, Márcia Aparecida Lodi Campos Melo, Luiz Antônio da Silva Lavradas, Plínio Gabriel Ferreira Lopes, Ingra Ianne Luiz Ornelas, Paula Lacerda de Barros, Paulo José da Mata Pereira, Paulo Niemeyer FilhoClinical Neurology...
      Royal Society of Chemistry (Great Britain) Society for Analytical Chemistry Society of Public Analysts (Great Britain)Dual-recognition-based determination of ctDNA via the clamping function of peptide nucleic acid and terminal protection of small-molecule-linked DNAAnalyst, 2020, Accepted ManuscriptDOI: 10.1039/D0AN01305F, PaperChaohui Chen, Rongxiang He, Zhengtao Zhang, Yong ChenA new dual-recognition fluorescent biosensor for circulating tumor DNA (ctDNA) detection has been developed, which combines...
      Allergology InternationalPlasma miR223 is a possible biomarker for diagnosing patients with severe atopic dermatitisPublication date: Available online 1 September 2020Source: Allergology InternationalAuthor(s): Risa Yasuike, Risa Tamagawa-Mineoka, Naomi Nakamura, Koji Masuda, Norito KatohAllergology InternationalWed Sep 02, 2020 17:44Mark above section as read AllergyPersonalized Medicine for allergy treatment: allergen immunotherapy still a unique and unmatched modelAbstract The introduction of...
      Diagnostic CytopathologyConditions associated with the need for additional needle passes in ultrasound‐guided thyroid fine‐needle aspiration with rapid on‐site pathology evaluationAbstract Background Rapid on‐site evaluation (ROSE) is a valuable tool for specimen adequacy assessment in thyroid ultrasound (US)‐guided fine‐needle aspiration (US‐guided FNA). To reduce the risk of nondiagnostic samples, additional needle passes may be needed at ROSE to ensure adequate sampling. Recommendations regarding...
      ANZ Journal of SurgeryEn bloc resection of locally perforated colonic malignancy with removal of iliopsoas and femoral nerve and primary anastomosisANZ Journal of SurgeryTue Sep 01, 2020 20:45How to repair a small umbilical hernia laparoscopicallyWe describe a step by step technique for repair of a small umbilical hernia laparoscopically that aims to provide an excellent technical and cosmetic result without a significant increase in operative time or cost. Patients report good quality of life...
     Asymmetric Transformation Driven by Confinement and Self‐Release in Single‐Layered Porous NanosheetAsymmetric transformation requires the use of chiral catalysts which is hampered by energy intensive processes such as high cost, inefficient recycle, and tedious separation. Here we report the use of single‐layered, chiral porous sheets with induced pore chirality for repeatable asymmetric transformation and self‐separation without the need of chiral catalysts or chiral auxiliaries. The asymmetric...
      Biomedicine & PharmacotherapyChlorogenic acid inhibits the proliferation of human lung cancer A549 cell lines by targeting annexin A2 <em>in vitro</em> and <em>in vivo</em>Publication date: November 2020Source: Biomedicine & Pharmacotherapy, Volume 131Author(s): Lei Wang, Hongwu Du, Peng ChenBiomedicine & PharmacotherapyWed Sep 02, 2020 18:10Ruboxistaurin maintains the bone mass of subchondral bone for blunting osteoarthritis progression by inhibition of osteoclastogenesis...
     Antitumor Effect of Shikonin, a PKM2 Inhibitor, in Cholangiocarcinoma Cell LinesBackground/Aim: Pyruvate kinase M2 (PKM2) is an enzyme that is predominantly overexpressed in various types of cancer. The role of PKM2 in liver fluke-associated cholangiocarcinoma (CCA) remains unclear. This study aimed to investigate the antitumor activity of shikonin, a PKM2 inhibitor, in CCA cells. Materials and Methods: Immunohistochemistry and immunoblotting were used to determine PKM2 expression in CCA tissues...
      Acta Otorrinolaringológica EspañolaPrimary stapedotomy: Influence of prosthesis diameter on hearing outcomePublication date: Available online 2 September 2020Source: Acta Otorrinolaringológica EspañolaAuthor(s): Pedro Salvador, Ricardo Costa, Francisco Silva, Rui FonsecaActa Otorrinolaringológica EspañolaWed Sep 02, 2020 15:14Mark above section as read Auris Nasus LarynxCarotid blowout—a rare but fatal complication of endoscopic submucosal dissection of superficial hypopharyngeal carcinoma after...
      pubmed: epilepsy treatmentThe mystery of the ketogenic diet: benevolent pseudo-diabetes.Related Articles The mystery of the ketogenic diet: benevolent pseudo-diabetes. Cell Cycle. 2019 09;18(18):2157-2163 Authors: Blagosklonny MV Abstract Designed a century ago to treat epilepsy, the ketogenic diet (KD) is also effective against obesity and diabetes. Paradoxically, some studies in rodents have found that the KD seemingly causes diabetes, contradicting solid clinical data in humans. This paradox...
      OncologyAn observational study of drug utilization and associated outcomes among adult patients diagnosed with BRAF-mutant advanced melanoma treated with first-line anti-PD-1 monotherapies or BRAF/MEK inhibitors in a community-based oncology setting.Related Articles An observational study of drug utilization and associated outcomes among adult patients diagnosed with BRAF-mutant advanced melanoma treated with first-line anti-PD-1 monotherapies or BRAF/MEK inhibitors in a community-based oncology...
      anesth pain medPharmacokinetics of lidocaine after bilateral ESP block.Related Articles Pharmacokinetics of lidocaine after bilateral ESP block. Reg Anesth Pain Med. 2020 Aug 31;: Authors: De Cassai A, Bonanno C, Padrini R, Geraldini F, Boscolo A, Navalesi P, Munari M Abstract INTRODUCTION: Erector spinae plane (ESP) block is an emerging interfascial block with a wide range of indications for perioperative analgesia and chronic pain treatment. Recent studies have focused their attention on mechanisms...
      Academic RadiologyHighly Accelerated Real-Time Free-Breathing Cine CMR for Patients With a Cardiac Implantable Electronic DevicePublication date: Available online 2 September 2020Source: Academic RadiologyAuthor(s): Sungtak Hong, KyungPyo Hong, Austin E. Culver, Ashitha Pathrose, Bradley D. Allen, Jane E. Wilcox, Daniel C. Lee, Daniel KimAcademic RadiologyWed Sep 02, 2020 17:56Mark above section as read European Journal of Nuclear Medicine and Molecular ImagingLong-term outcome of "Sandwich" chemo-PRRT:...

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    Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,00306932607174,alsfakia@gmail.com,
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