Παρασκευή, 10 Νοεμβρίου 2017

Vaccines, Vol. 5, Pages 43: A New Whooping Cough Vaccine That May Prevent Colonization and Transmission

Vaccines, Vol. 5, Pages 43: A New Whooping Cough Vaccine That May Prevent Colonization and Transmission

Vaccines doi: 10.3390/vaccines5040043

Authors: Michael Brennan

This article is a Letter to the Editor. The major purpose of this Letter is to highlight the development of a new genetically altered whooping cough vaccine. Recently a baboon model has been used to show that this next generation pertussis vaccine can prevent colonization, as well as disease, and elicit antibodies against major pertussis antigens. Two phase I clinical trials have been performed, showing that this new vaccine is safe in humans, and a phase II trial will be performed in the US in 2018.



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