Τρίτη 31 Οκτωβρίου 2017

Glucose starvation impairs DNA repair in tumour cells selectively by blocking histone acetylation

Tumour cells are characterized by aerobic glycolysis and thus have high glucose consumption. Because repairing radiation-induced DNA damage is an energy-demanding process, we hypothesized that glucose starvation combined with radiotherapy could be an effective strategy to selectively target tumour cells.

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