As part of its potential pro-tumorigenic actions, Transforming Growth Factor-(TGF)-β induces epithelial-mesenchymal transition (EMT) in hepatocellular carcinoma (HCC) cells. Whether EMT induces changes in tumor cell plasticity has not been fully explored yet. Here, we analyze the effects of TGF-β on the EMT and stem-related properties of HCC cells and the potential correlation among those processes. The translational aim of the study was to propose a TGF-β/EMT/stem gene signature that would help in recognizing HCC patients as good candidates for anti-TGF-β therapy.
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Publication date: 18 April 2017 Source: Cell Reports, Volume 19, Issue 3 Author(s): David Estoppey, Chia Min Lee, Marco Janoschke, Boon He...
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Abstract Functionalised electrospun polyamide-6 (PA-6) nanofibres incorporating gadolinium oxide nanoparticles conjugated to zinc tetracar...
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Cytokine-dependent renewal of stem cells is a fundamental requisite for tissue homeostasis and regeneration. Spermatogonial progenitor cells...
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Yahoo Health Ken Brookes Lost 102 Pounds: 'I Never Want to Go Back to Being Unhealthy' Yahoo Health My wife died of ovarian ...
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Radiation Research, Volume 187, Issue 6 , Page 647-658, June 2017. from #AlexandrosSfakianakis via Alexandros G.Sfakianakis on Inoreader ...
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Abstract Background Cells in the intervertebral disc have unique phenotypes and marker genes that separate the nucleus pulposus (NP), an...
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Publication date: Available online 23 February 2017 Source: Journal of Biomechanics Author(s): Lipika Parida, Udita Uday Ghosh, Venkat Pad...
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