Δευτέρα 15 Ιανουαρίου 2018

CT imaging of primary pancreatic lymphoma: experience from three referral centres for pancreatic diseases

Abstract

Purpose

To describe CT characteristics of primary pancreatic lymphoma (PPL), a rare disease with features in common with adenocarcinoma.

Materials and methods

Fourteen patients were enrolled. CT: unenhanced scan, contrast-enhanced pancreatic and venous phases. Image analysis: tumour location; peri-pancreatic vessel encasement; necrosis; enlarged lymph nodes; fat stranding; enlarged bile duct and pancreatic duct; neoplasm longest dimension, volume and density.

Results

Histopathological diagnoses: follicular non-Hodgkin lymphoma (5/14), diffuse large B-cell lymphoma (6/14) and high-grade B-cell lymphoma not otherwise specified (3/14). Six of 14 PPLs were located in the pancreatic head and 7/14 in the body-tail; 1/14 involved the whole gland. In 5/14 cases the superior mesenteric artery and vein were encased; splenic vein and artery encasement was depicted in 2 PPLs. Necrosis was present in 2/14. Enlarged retroperitoneal lymph nodes were found in 11 cases and fat stranding in all patients. The bile duct was dilated in six cases and the pancreatic duct in five. Mean neoplasm longest diameter and volume were 8.05 cm and 210.8 cm3. Mean tumour attenuation values were 39.1 HU at baseline, 60.6 HU in the pancreatic phase and 71.4 HU in the venous phase.

Conclusions

PPL presents as a large mass lesion with delayed homogeneous enhancement; peri-pancreatic fat stranding and vessel encasement are present, without vascular infiltration. Pancreatic duct dilatation is rare.

Key points

Primary pancreatic lymphoma (PPL) is a rare haematological disease

• PPL presents imaging features in common with pancreatic carcinoma but also some distinctive findings

The majority of PPLs are large lesions with delayed homogeneous enhancement

Peri-pancreatic fat stranding and vessel encasement are common in PPL

Vascular infiltration and pancreatic duct dilatation are rare in PPL



from Imaging via alkiviadis.1961 on Inoreader http://ift.tt/2DismkM

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