Τετάρτη 20 Δεκεμβρίου 2017

Rapid melanoma induction in mice expressing oncogenic BrafV600E using Mitf-cre

Mutations in the BRAF serine/threonine kinase are found in 50-70% of human cutaneous melanomas. The most common alteration is V600E, a change which induces constitutive activity. Two groups have independently developed transgenic mice to express BrafV600E at physiological levels from the endogenous Braf locus after recombination mediated by cre recombinase.

This article is protected by copyright. All rights reserved.



from #AlexandrosSfakianakis via Alexandros G.Sfakianakis on Inoreader http://ift.tt/2B5HvBE
via IFTTT

Δεν υπάρχουν σχόλια:

Δημοσίευση σχολίου

Δημοφιλείς αναρτήσεις