Πέμπτη 23 Φεβρουαρίου 2017

Persistent kallikrein5 activation induces atopic dermatitis-like skin architecture independent of PAR2 activity

Persistently increased serine protease kallikrein 5 modifies skin barrier proteins, upregulates AD-related cytokine expression and induces AD-like skin architecture. Inhibition of KLK5 may offer potential as a treatment strategy in AD.

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