<span class="paragraphSection"><div class="boxTitle">Background</div>In Australia, high uptake of the quadrivalent human papillomavirus (4vHPV) vaccine has led to reductions in the prevalence of human papillomavirus (HPV) genotypes 6, 11, 16, and 18 in women and girls aged ≤25 years. We evaluated the impact of the program impact on HPV prevalence in unvaccinated male subjects.<div class="boxTitle">Methods</div>Sexually active heterosexual male subjects aged 16–35 years were recruited in 2014–2016. Participants provided a self-collected penile swab sample for HPV genotyping (Roche Linear Array) and completed a demographic and risk factor questionnaire.<div class="boxTitle">Results</div>The prevalence of 4vHPV genotypes among 511 unvaccinated male subjects was significantly lower in those aged ≤25 than in those aged >25 years: 3.1% (95% confidence interval, 1.5%–5.7%) versus 13.7% (8.9%–20.1%), respectively (<span style="font-style:italic;">P</span> < .001); adjusted prevalence ratio, 0.22 (.09–.51; <span style="font-style:italic;">P</span> < .001). By contrast, the prevalence of high-risk HPV genotypes other than 16 and 18 remained the same across age groups: 16.8% (95% confidence interval, 12.6%–21.9%) in men aged ≤25 years and 17.9% (12.4%–25.0%) in those aged >25 years (<span style="font-style:italic;">P</span> = .76); adjusted prevalence ratio, 0.98, (.57–1.37; <span style="font-style:italic;">P</span> = .58).<div class="boxTitle">Conclusions</div>A 78% lower prevalence of 4vHPV genotypes was observed among younger male subjects. These data suggest that unvaccinated men may have benefited from herd protection as much as women from a female-only HPV vaccination program with high coverage.</span>
from #AlexandrosSfakianakis via Alexandros G.Sfakianakis on Inoreader http://ift.tt/2j7gf0G
via IFTTT
Εγγραφή σε:
Σχόλια ανάρτησης (Atom)
Δημοφιλείς αναρτήσεις
-
Publication date: Available online 4 January 2018 Source: European Journal of Radiology Author(s): Peiyao Zhang, Jing Wang, Qin Xu, Zhen...
-
Related Articles Anatomic parameters of the sacral lamina for osteosynthesis in transverse sacral fractures. Surg Radiol Anat....
-
Background Hyperthyroidism is associated with increased thrombotic risk. As contact system activation through formation of neutrophil extrac...
-
Consulting to Finance: How to Network, Tell Your Story, Spin Your Resume, and Dominate Your Investment Banking and Private Equity Interviews...
-
Publication date: March 2017 Source: Anesthesiology Clinics, Volume 35, Issue 1 Author(s): Onyi C. Onuoha, Robert R. Gaiser from #Ale...
-
Abstract Purpose Investigate in patients with metastatic and/or irresectable colorectal cancer treated with systemic treatment with cape...
-
Abstract Objectives (1) To illustrate and describe the main types of pancreatic surgery; (2) to discuss the normal findings after pancre...
-
Medicine by Alexandros G. Sfakianakis,Αλέξανδρος Γ. Σφακιανάκης A Novel Technique for Endoscopic Repair of Large Anterior Skull Base Defect...
Δεν υπάρχουν σχόλια:
Δημοσίευση σχολίου