Τρίτη, 6 Αυγούστου 2019

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,00306932607174,alsfakia@gmail.com,


Case Studies in Social Medicine: The Right and Left Hands of the State — Two Patients at Risk of...
Case Studies in Social Medicine: The Right and Left Hands of the State — Two Patients at Risk of DeportationA. Berlin and OthersN Engl J Med 381:197, July 18, 2019Audio | CommentsORIGINAL ARTICLENeural-Tube Defects and Antiretroviral Treatment Regimens in BotswanaR. Zash and OthersN Engl J Med, July 22, 2019Transfusion Volume for Children with Severe Anemia in AfricaK. Maitland and OthersN Engl J Med 381:420, August 1, 2019Immediate Transfusion in African Children with Uncomplicated Severe AnemiaK....
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Sister First, Doctor Second  S. Sediqzadah N Engl J Med 381:108, July 11, 2019
Sister First, Doctor Second S. SediqzadahN Engl J Med 381:108, July 11, 2019
Αλέξανδρος Γ. Σφακιανάκης
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Professionalism: An Archaeology Abstract For more than two decades, classes on "professionalism" have...
Professionalism: An ArchaeologyAbstractFor more than two decades, classes on "professionalism" have been the dominant platform for the non-technical socialization of medical students. It thus subsumes elements of previous foundation courses in bioethics and "medicine and society" in defining the appropriate relation between practitioners, patients, and society-at-large. Despite its importance, there is, however, no clear definition of what "professionalism" entails or the manner in which it serves...
Αλέξανδρος Γ. Σφακιανάκης
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Is Molecular Diagnosis Necessary for Children with Duchenne Muscular Dystrophy? Theme : Neonatology...
Is Molecular Diagnosis Necessary for Children with Duchenne Muscular Dystrophy?Theme : NeonatologyNews in BriefAwakening the Spirits and Addressing the Safety Concerns in ChildhoodFlexible Bronchoscopic Removal of Foreign Bodies from Airway of Children: Single Center Experience Over 12 YearsAbstractObjectiveTo report our experience of tracheobronchial foreign body removal in children using flexible bronchoscopy as the primary mode.MethodsHospital records of tracheobronchial foreign body extractions...
Αλέξανδρος Γ. Σφακιανάκης
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Imaging and Surgical Treatment of Primary Pulmonary Artery Sarcoma Abstract Primary pulmonary artery...
Imaging and Surgical Treatment of Primary Pulmonary Artery SarcomaAbstractPrimary pulmonary artery sarcoma is a rare tumor originating from the pulmonary artery tree. Given the low incidence, few centers have reported on more than a handful of cases. Because of its rarity it is also commonly misdiagnosed as pulmonary embolism. Multi-modality diagnostic imaging and recognition of specific imaging characteristics along with a high index of suspicion is required to make the correct diagnosis and expedite...
Αλέξανδρος Γ. Σφακιανάκης
1h
The pristine nature of river Ganges: its qualitative deterioration and suggestive restoration strategies...
The pristine nature of river Ganges: its qualitative deterioration and suggestive restoration strategiesAbstractThe river Ganges, the National Heritage, and the lifeline of millions of Indians, unfortunately, ranked the second most polluted rivers of the world in 2017. This review reveals the current trends of the water quality of the Ganges assessed around 36 stretches during 2012–2016, to indicate an improvement around 6 (16.7%), deterioration around 14 (38.9%), and non-significant changes around...
Αλέξανδρος Γ. Σφακιανάκης
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Introduction Vol. 2 Issue 2 International Journal of Community Well-Being Correction to: Economy Doesn't...
Introduction Vol. 2 Issue 2 International Journal of Community Well-BeingCorrection to: Economy Doesn't Buy Community Wellbeing: a Study of Factors Shaping Community Wellbeing in South KoreaThis paper was supported by the Ministry of Education of the Republic of Korea and the National Research Foundation of Korea (NRF-2016S1A3A2924563).Correction to: Community Well-Being in Neighbourhoods: Achieving Community and Open-Minded Space through Engagement in NeighbourhoodsThis work was supported by the...
Αλέξανδρος Γ. Σφακιανάκης
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A Step in the Right Direction But We Must Resist Identity Politics Science Has Always Been Ideological,...
A Step in the Right Direction But We Must Resist Identity PoliticsScience Has Always Been Ideological, You Just Don't See ItPower and Privilege in the Field of Sexuality Research and BeyondSexual Science versus Progressive Advocacy: The Need for ResistanceAdvancing Our Scientific Understanding of Sexual HarassmentShades of Rind: Ought We Be Surprised?Sexual Harassment: "I Just Do Not Feel Safe"Are Healthy Parental Attachments and Resilience to Societal Objectification Basic to Women's Sexual Health?The...
Αλέξανδρος Γ. Σφακιανάκης
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A Multiscale Hierarchical Threshold-Based Completed Local Entropy Binary Pattern for Texture Classification...
A Multiscale Hierarchical Threshold-Based Completed Local Entropy Binary Pattern for Texture ClassificationAbstractOver the year, visual texture analysis has come to be recognized as one of the most important methods in the area of medical image analysis and understanding, face description and detection, and so on. The goal of texture descriptors is to capture the general characteristic of textures such as dependency as well as invariance properties. Among all the texture descriptors, the binary...
Αλέξανδρος Γ. Σφακιανάκης
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Journal of Cutaneous Pathology Early View Online Version of Record before inclusion in an issue ORIGINAL...
Journal of Cutaneous PathologyEarly ViewOnline Version of Record before inclusion in an issueORIGINAL ARTICLESVariable loss of CD30 expression by immunohistochemistry in recurrent cutaneous CD30+ lymphoid neoplasms treated with brentuximab vedotinAmrita Goyal, Sanjay Patel, Kavita Goyal, Elizabeth A. Morgan, Ruth K. ForemanVersion of Record online: 02 August 2019CASE REPORTSMalignant melanoma with metaplastic cartilaginous transdifferentiation: A case reportJuliett Berro, Nour Abdul Halim, Chirine...
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Cellular & Molecular Immunology
RESEARCH HIGHLIGHTSAutophagy induced by STING, an unnoticed and primordial function of cGASJunjie Yang, Xiaoshan Tang, Kutty Selva Nandakumar & Kui Cheng Cellular & Molecular Immunology 2019 16 :683 - 684; May 29, 2019; 10.1038/s41423-019-0240-2Abstract | Full TextARTICLET cells from induced and spontaneous models of SLE recognize a common T cell epitope on β2-glycoprotein IDavid Salem, Rebecca Subang, Masataka Kuwana, Jerrold S. Levine & Joyce Rauch Cellular & Molecular Immunology...
Αλέξανδρος Γ. Σφακιανάκης
1h
Bullous pemphigoid with linear lesions and antibodies exclusively against the soluble ectodomain of...
Bullous pemphigoid with linear lesions and antibodies exclusively against the soluble ectodomain of BP180 (LAD‐1)Hamidreza Mahmoudi, Roja Toosi, Kambiz Kamyab, Detlef Zillikens, Enno Schmidt, Maryam DaneshpazhoohVersion of Record online: 28 July 2019
Αλέξανδρος Γ. Σφακιανάκης
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Chemical profiling and functional properties of dietary fibre rich inner and outer bracts of culinary...
Chemical profiling and functional properties of dietary fibre rich inner and outer bracts of culinary banana flowerAbstractThe present study endeavoured to evaluate the nutritional, phytochemical and functional properties of outer and inner bracts of culinary banana flower which is a by-product of banana production. Both outer and inner bracts were found to be rich in dietary fibre (61.13 and 66.22%, respectively) along with other chemical compositions including proximate, minerals, and antioxidant-rich...
Αλέξανδρος Γ. Σφακιανάκης
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Mediators of physical activity adoption and maintenance among breast cancer survivors Abstract The purpose...
Mediators of physical activity adoption and maintenance among breast cancer survivorsAbstractThe purpose of this study is to explore the mediators associated with physical activity (PA) within the adoption and maintenance phase of a PA intervention trial among breast cancer survivors. Overall, 192 breast cancer survivors (average age = 55.9 years) were randomized to an Intervention or Control group. Both groups received 8 calls in the first 3-months, 3 monthly calls, and then entered a no-contact...
Αλέξανδρος Γ. Σφακιανάκης
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Associations between Perceived Homophobia, Community Connectedness, and Having a Primary Care Provider...
Associations between Perceived Homophobia, Community Connectedness, and Having a Primary Care Provider among Gay and Bisexual MenAbstractAccording to the minority stress model and social evaluation theory, stigma increases negative health outcomes in sexual minorities, and those with greater connection to a community appraise their lives with respect to fellow community members. This study was a secondary analysis of data from the online 2010 Social Justice Sexuality Project and examined associations...
Αλέξανδρος Γ. Σφακιανάκης
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nternational Journal of Dermatology  Early View Online Version of Record before inclusion in an issue...
nternational Journal of Dermatology Early ViewOnline Version of Record before inclusion in an issueCorrespondenceAcquired macronychia with painful toe: osteoid osteomaSeung Hee Woo BSc, Keunyoung Hur MD, Je‐Ho Mun MD, PhDVersion of Record online: 01 August 2019ReportsDermoscopic features of lichen planopilaris in Northern Iran: a prospective observational studyHojat Eftekhari MD, Seyyede Zeinab Azimi MD, Rana Rafiei MD, Abbas Darjani MD, Narges Alizadeh MD, Elahe Rafiei MSc, Reyhaneh Ghadarjani MD, Kaveh...
Αλέξανδρος Γ. Σφακιανάκης
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During Cycling What Limits Maximum Mechanical Power Output at Cadences above 120 rpm? Purpose A key...
During Cycling What Limits Maximum Mechanical Power Output at Cadences above 120 rpm?Purpose A key determinant of muscle coordination and maximum power output during cycling is pedalling cadence. During cycling the neuromuscular system may select from numerous solutions that solve the task demands while producing the same result. For more challenging tasks fewer solutions will be available. Changes in the variability of individual muscle excitations (EMG) and multi-muscle coordination, quantified...
Αλέξανδρος Γ. Σφακιανάκης
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A Preliminary Study Evaluating the Safety and Efficacy of Bumetanide, an NKCC1 Inhibitor, in Patients...
A Preliminary Study Evaluating the Safety and Efficacy of Bumetanide, an NKCC1 Inhibitor, in Patients with Drug-Resistant EpilepsyThe correct name of the co-author should be ''Vajiheh Aghamollaii'', and not ''Vajihe Aghamollaii'' as given in the original publication of the article.Objective Derivation of the Morphology and Staging of Visual Field Loss Associated with Long-Term Vigabatrin TherapyAbstractBackgroundThe morphology and between-eye symmetry of the visual field loss associated with the...
Αλέξανδρος Γ. Σφακιανάκης
1h
Pembrolizumab for Locally Advanced or Metastatic Urothelial Cancer Where Cisplatin is Unsuitable: An...
Pembrolizumab for Locally Advanced or Metastatic Urothelial Cancer Where Cisplatin is Unsuitable: An Evidence Review Group Perspective of a NICE Single Technology AppraisalAbstractAs part of its Single Technology Appraisal (STA) process, the National Institute for Health and Care Excellence (NICE) invited the manufacturer (Merck Sharp & Dohme) of pembrolizumab (Keytruda®) to submit evidence of its clinical and cost effectiveness for the treatment of locally advanced or metastatic urothelial cancer...
Αλέξανδρος Γ. Σφακιανάκης
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Let us 'bring back the forest' Detecting dynamic system regime boundaries with Fisher information:...
Let us 'bring back the forest'Detecting dynamic system regime boundaries with Fisher information: the case of ecosystemsAbstractThe direct measurement of the resilience (resistance to disturbances) of an ecosystem's current regime (or "alternative stable state") remains a key concern for managing human impacts on these ecosystems and their risk of collapse. Approaches which utilize statistics or information theory have demonstrated utility in identifying regime boundaries. Here, we use Fisher information...
Αλέξανδρος Γ. Σφακιανάκης
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Strengthening Quadriceps Muscles with Neuromuscular Electrical Stimulation Following Total Hip Replacement:...
Strengthening Quadriceps Muscles with Neuromuscular Electrical Stimulation Following Total Hip Replacement: a ReviewAbstractPurpose of ReviewFunctional recovery from total hip replacement can be suboptimal and deficits in quadriceps muscle strength may hinder the return to activities of daily living. Neuromuscular electrical stimulation (NMES) devices have long been used to preserve and restore skeletal muscle mass and function following periods of muscle atrophy due to immobilisation. Here, we evaluate...
Αλέξανδρος Γ. Σφακιανάκης
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Response-level processing during visual feature search: Effects of frontoparietal activation and adult...
Response-level processing during visual feature search: Effects of frontoparietal activation and adult ageAbstractPrevious research suggests that feature search performance is relatively resistant to age-related decline. However, little is known regarding the neural mechanisms underlying the age-related constancy of feature search. In this experiment, we used a diffusion decision model of reaction time (RT), and event-related functional magnetic resonance imaging (fMRI) to investigate age-related...
Αλέξανδρος Γ. Σφακιανάκης
1h
Serious clinical events in HIV-positive persons with chronic kidney disease (CKD) Objectives: Predictors...
Serious clinical events in HIV-positive persons with chronic kidney disease (CKD)Objectives: Predictors of chronic kidney disease (CKD) amongst HIV-positive persons are well established, but insights into the prognosis after CKD including the role of modifiable risk factors are limited. Design: Prospective cohort study Methods: D:A:D participants developing CKD (confirmed, >3 months apart, eGFR ≤ 60 mL/min/1.73 m2 or 25% eGFR decrease when eGFR ≤ 60) were followed to incident serious clinical...
Αλέξανδρος Γ. Σφακιανάκης
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Dermatologic Therapy Early View Online Version of Record before inclusion in an issue LETTERS TO...
Dermatologic TherapyEarly ViewOnline Version of Record before inclusion in an issueLETTERS TO THE EDITORBullous pemphigoid in a patient treated with nivolumabCarlos Cuenca‐Barrales, Beatriz Espadafor‐López, Antonio Martínez‐López, Bárbara Cancela‐Díez, Ricardo Ruiz‐Villaverdee13030 | Version of Record online: 01 August 2019REVIEW ARTICLESTiming of quality of life improvements in psoriatic patients treated with different systemic therapiesGiuseppe Pistone, Rosario Gurreri, Giovanna Tilotta, Paolo...
Αλέξανδρος Γ. Σφακιανάκης
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A Comparison of Intracochlear Pressures During Ipsilateral and Contralateral Stimulation With a Bone...
A Comparison of Intracochlear Pressures During Ipsilateral and Contralateral Stimulation With a Bone Conduction ImplantObjectives: To compare contralateral to ipsilateral stimulation with percutaneous and transcutaneous bone conduction implants. Background: Bone conduction implants (BCIs) effectively treat conductive and mixed hearing losses. In some cases, such as in single-sided deafness, the BCI is implanted contralateral to the remaining healthy ear in an attempt to restore some of the benefits...
Αλέξανδρος Γ. Σφακιανάκης
2h
Verbesserung von Tinnitusdistress, Lebensqualität und psychologischen Komorbiditäten durch Cochleaimplantation...
Verbesserung von Tinnitusdistress, Lebensqualität und psychologischen Komorbiditäten durch Cochleaimplantation einseitig ertaubter PatientenZusammenfassungHintergrundPatienten mit einseitiger Ertaubung (SSD) fehlt die Fähigkeit des Richtungshörens, und das Sprachverstehen im Störgeräusch ist eingeschränkt. Zudem liegt eine hohe Tinnitusprävalenz vor. Dies kann zu reduzierter Lebensqualität (HRQoL) und psychologischen Komorbiditäten führen. Ziel dieser Studie war die Untersuchung des Einflusses der...
Αλέξανδρος Γ. Σφακιανάκης
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Ultrasound Guided Sacroiliac Joint Injections No abstract available Clinical Findings and Electrodiagnostic...
Ultrasound Guided Sacroiliac Joint InjectionsNo abstract availableClinical Findings and Electrodiagnostic Testing in Ulnar Neuropathy at the Elbow and Differences According to Site and Type of Nerve DamageObjective To evaluate the clinical and electrodiagnostic testing (EDX) in ulnar neuropathy at the elbow (UNE) and differences according to site (humeroulnar arcade, HUA, vs. retroepicondylar groove, REG) and injury physiopathology (axonal vs. demyelinating), through prospective multicenter case-control...
Αλέξανδρος Γ. Σφακιανάκης
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Deutsche Zeitschrift für Akupunktur
DGfANPersonaliaAkupunktur ist etabliertPalliativmedizin und OnkologieNachruf auf Horst BeckeAkupunktur bei Veteranen mit dauerhaften Schlafstörungen nach milder traumatischer HirnschädigungDÄGfALeserbriefeAkupressur als begleitende Behandlung in der Onkologie und PalliativmedizinKomplexbehandlung einer Finalbegleitung
Αλέξανδρος Γ. Σφακιανάκης
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Genetics in Medicine
IN THIS ISSUEIn This IssueRoni Dengler Genetics in Medicine 2019 21 :1673 - 1673; August 01, 2019; 10.1038/s41436-019-0605-zAbstract | Full TextNEWSNewsRoni Dengler Genetics in Medicine 2019 21 :1674 - 1674; August 01, 2019; 10.1038/s41436-019-0604-0Abstract | Full TextSYSTEMATIC REVIEWCharacteristics and evaluation outcomes of genomics curricula for health professional students: a systematic literature reviewDivya Talwar, Wei-Ju Chen, Yu-Lyu Yeh, Margaret Foster, Salah Al-Shagrawi et al. Genetics...
Αλέξανδρος Γ. Σφακιανάκης
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Nephrology  A Summary of Recently Published Activity PERSPECTIVE Combating EPA Rollbacks — Health...
Nephrology A Summary of Recently Published ActivityPERSPECTIVECombating EPA Rollbacks — Health Care's Response to a Retreat on ClimateG. McCarthy and A. BernsteinN Engl J Med, July 24, 2019Implementation Science for the BedsideE.H. GengN Engl J Med 381:304, July 25, 2019ORIGINAL ARTICLERoxadustat for Anemia in Patients with Kidney Disease Not Receiving DialysisN. Chen and OthersN Engl J Med, July 24, 2019Roxadustat Treatment for Anemia in Patients Undergoing Long-Term DialysisN. Chen and OthersN...
Αλέξανδρος Γ. Σφακιανάκης
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Role of Metoprolol Succinate in the Treatment of Heart Failure and Atrial Fibrillation: A Systematic...
Role of Metoprolol Succinate in the Treatment of Heart Failure and Atrial Fibrillation: A Systematic ReviewBackground: Beta-blockers are one of the most important classes of cardiovascular agents and have been considered a cornerstone therapy in heart diseases, such as heart failure (HF) and atrial fibrillation (AF). Among different beta-blockers, metoprolol is a selective beta1-adrenergic antagonist, which has been extensively used since the 1970s. Areas of Uncertainty: Although current guidelines...
Αλέξανδρος Γ. Σφακιανάκης
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Neurology/Neurosurgery   A Summary of Recently Published Activity PERSPECTIVE Combating EPA Rollbacks...
Neurology/Neurosurgery  A Summary of Recently Published ActivityPERSPECTIVECombating EPA Rollbacks — Health Care's Response to a Retreat on ClimateG. McCarthy and A. BernsteinN Engl J Med, July 24, 2019ORIGINAL ARTICLERimegepant, an Oral Calcitonin Gene–Related Peptide Receptor Antagonist, for MigraineR.B. Lipton and OthersN Engl J Med 381:142, July 11, 2019Trial of Galcanezumab in Prevention of Episodic Cluster HeadacheP.J. Goadsby and OthersN Engl J Med 381:132, July 11, 2019Quick TakeBrief Report:...
Αλέξανδρος Γ. Σφακιανάκης
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 Molecular Testing for Flu Catching up, But Still Lagging Far Behind RIDTsPublished on Aug 05, 2019 Comparison...
 Molecular Testing for Flu Catching up, But Still Lagging Far Behind RIDTsPublished on Aug 05, 2019 Comparison of KRAS Liquid Biopsy Kits Confirms Differences at Low Mutant Allele FractionPublished on Aug 02, 2019 Twist Bioscience Touts Longer Oligos, NGS-Based GenotypingPublished on Aug 02, 2019 ETH Zurich Team Uses NMR for Multi-Omic Analysis of RNA Folding NetworkPublished on Aug 02, 2019Automated Genomic DNA Extraction from Large Volume Whole BloodIn this poster from Beckman Coulter learn about...
Αλέξανδρος Γ. Σφακιανάκης
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Otolaryngology–Head and Neck Surgery  View online OnlineFirst Alert Original ResearchPostoperative...
Otolaryngology–Head and Neck Surgery View onlineOnlineFirst AlertOriginal ResearchPostoperative Opioid Prescribing and Consumption Patterns after TonsillectomyStephanie Choo, Stephen Nogan, Laura MatrkaOtolaryngology–Head and Neck SurgeryJul 30, 2019 | OnlineFirstInvited ArticleContributions of Contemporary Human Temporal Bone Histopathology to Clinical OtologyDebara L. Tucci, Joni K. DohertyOtolaryngology–Head and Neck SurgeryJul 30, 2019 | OnlineFirstOriginal ResearchPattern of Intraoperative Parathyroid...
Αλέξανδρος Γ. Σφακιανάκης
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Ear, Nose & Throat Journal  View online OnlineFirst Alert OtherBilateral Vocal Fold Paralysis...
Ear, Nose & Throat Journal  View onlineOnlineFirst AlertOtherBilateral Vocal Fold Paralysis Secondary to Intrathyroidal Calcifications Following Remote Administration of Radioactive Iodine Therapy for Graves DiseaseAlexander D. Karabachev, Nathan C. Grohmann, Mirabelle SajiseviEar, Nose & Throat JournalAug 2, 2019 | OnlineFirstResearch ArticleThe Feasibility of Utilizing Smartphone Flashlights as an Alternative Endoscopic Light Source in Emergency SituationsJennifer Johanna Butler, Stephen...
Αλέξανδρος Γ. Σφακιανάκης
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Lessons Learned From the Opioid Epidemic  Joshua M. Sharfstein, MD; Yngvild Olsen, MD, MPH Relative...
Lessons Learned From the Opioid Epidemic Joshua M. Sharfstein, MD; Yngvild Olsen, MD, MPHRelative Value Units and the Measurement of Physician PerformanceMichael Nurok, MBChB, PhD; Bruce Gewertz, MDAudio Interview: Relative Value Units and the Measurement of Physician PerformanceAUDIOAudio InterviewRelative Value Units and the Measurement of Physician Performance
Αλέξανδρος Γ. Σφακιανάκης
2h
Remember 2 Things: Proper Emergency Care By Steve Whitehead  Steve Whitehead discusses two ways providers...
Remember 2 Things: Proper Emergency CareBy Steve Whitehead Steve Whitehead discusses two ways providers can be confident that they provided exceptional, authorized care to their patients
Αλέξανδρος Γ. Σφακιανάκης
2h
Understanding compartment syndrome by type By EMS1 Staff Compartment syndrome should be considered early...
Understanding compartment syndrome by typeBy EMS1 StaffCompartment syndrome should be considered early to prevent dire consequences for the patient.
Αλέξανδρος Γ. Σφακιανάκης
2h
Experimental Dermatology Interleukin‐17A affects extracellular vesicles release and cargo in human...
Experimental DermatologyInterleukin‐17A affects extracellular vesicles release and cargo in human keratinocytesGiorgio Mangino, Marco Iuliano, Silvia Carlomagno, Nicoletta Bernardini, Paolo Rosa, Maria Vincenza Chiantore, Nevena Skroza, Antonella Calogero, Concetta Potenza, Giovanna RomeoFirst Published: 02 August 2019Focus Theme Issue: ViewpointInteraction of peripheral nerves and mast cells, eosinophils, and basophils in the development of pruritusChisa Nakashima, Yoshihiro Ishida, Akihiko Kitoh, Atsushi...
Αλέξανδρος Γ. Σφακιανάκης
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Do Neti Pots Really Work?Nasal irrigation may be a good way to relieve your stuffy nose. Here's how...
Do Neti Pots Really Work?Nasal irrigation may be a good way to relieve your stuffy nose. Here's how it works.Read More  
Αλέξανδρος Γ. Σφακιανάκης
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Fertility Preservation Outcomes in Adolescent and Young Adult Feminizing Transgender Patients Emily...
Fertility Preservation Outcomes in Adolescent and Young Adult Feminizing Transgender PatientsEmily P. Barnard, Cherie Priya Dhar, Stephanie S. Rothenberg, Marie N. Menke, Selma F. Witchel, Gerald T. Montano, Kyle E. Orwig and Hanna Valli-PulaskiAdvancing the Agenda in Pediatric Mental Health EducationCori Green, John T. Walkup, Susan Bostwick and William TrochimCommentaryFertility Preservation Outcomes and Considerations in Transgender and Gender-Diverse YouthJason Rafferty
Αλέξανδρος Γ. Σφακιανάκης
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The State of Resting State Networks Functional MRI (fMRI) is currently used for pre-surgical planning,...
The State of Resting State NetworksFunctional MRI (fMRI) is currently used for pre-surgical planning, but is often limited to information on the motor and language systems. Resting state fMRI can provide more information on multiple other networks to the neurosurgeon and neuroradiologist; however, currently, these networks are not well known among clinicians. The purpose of this manuscript is to provide an introduction to these networks for the clinician and to discuss how they could be used in the...
Αλέξανδρος Γ. Σφακιανάκης
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Comparison of outcomes after human leukocyte antigen-matched and haploidentical hematopoietic stem-cell...
Comparison of outcomes after human leukocyte antigen-matched and haploidentical hematopoietic stem-cell transplantation for multiple myelomaBackground: Allogeneic stem-cell transplantation (SCT) is a well-established immunotherapeutic strategy for multiple myeloma (MM) with a potent and often sustained graft-vs.-myeloma effect. This multicenter investigation aimed to analyze the complications and survival of haploidentical SCT in patients with MM, and compare the main outcomes with matched-related...
Αλέξανδρος Γ. Σφακιανάκης
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Early Mechanical Hearing Devices    Sarli, Cathy C.; Uchanski, Rosalie M. PhD The Hearing Journal: August...
Early Mechanical Hearing Devices   Sarli, Cathy C.; Uchanski, Rosalie M. PhDThe Hearing Journal: August 2019 - Volume 72 - Issue 8 - p 8,9doi: 10.1097/01.HJ.0000579564.45174.32Hearing Aids DevelopmentOver the years, hearing devices have taken many shapes and forms. The first article of this series, published in The Hearing Journal's April 2019 issue, discussed the earliest of these mechanical devices—the "cupped" human hand, which provides an acoustic gain of up to 7 to 17 dB, benefiting listeners...
Αλέξανδρος Γ. Σφακιανάκης
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The Hearing Journal's August issue  Are You Compensated Fairly? Salary Survey Results...
The Hearing Journal's August issue Are You Compensated Fairly? Salary Survey Results RevealedBy Gordon GlantzThe Hearing Journal's salary survey looks into current trends and pressing issues affecting the career satisfaction and advancement of today's audiology professionals, including the gender pay gap, mentorship in the industry, among others. Read more.AuD Externships: Building, Managing Successful ExperiencesBy Sharon Van Hyfte, AuD, CCC-AThe tried-and-true externship guidelines observed by...
Αλέξανδρος Γ. Σφακιανάκης
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Navel to Knees With Chlorhexidine Gluconate: Preventing Catheter-Associated Urinary Tract Infections...
Navel to Knees With Chlorhexidine Gluconate: Preventing Catheter-Associated Urinary Tract InfectionsUrinary tract infections are the most common type of health care–associated infection, and greater than 75% of them are attributed to an indwelling urinary catheter. A catheter-associated urinary infection may lead to a longer hospital length of stay by as many as 4 days. A new patient care standard requiring twice-daily chlorhexidine cleansing from umbilicus to knees was implemented on all patients...
Αλέξανδρος Γ. Σφακιανάκης
2h
Effects of monoamine uptake inhibitors on pain-related depression of nesting in mice Pain is a significant...
Effects of monoamine uptake inhibitors on pain-related depression of nesting in micePain is a significant public health problem, and assessment of pain-related impairment of behavior is a key clinical indicator and treatment target. Similar to opioids and NSAIDs, dopamine (DA) transporter inhibitors block pain-related depression of intracranial self-stimulation (ICSS) in rats. The primary goal of the present study was to determine if the effects of monoamine uptake inhibitors on pain-related depression...
Αλέξανδρος Γ. Σφακιανάκης
2h
Endocrine Disruption and Reproductive Health from a Clinical Perspective A. Clinical aspects of endocrine disruption in humans B. Clinical dimorphism of EDCs on male and female reproduction C. Experimental and clinical evidence of EDCs and potential mechanisms III. Clinical and Translational Impacts of EDCs on Female Reproduction A. Introduction to female reproductive development and function B. Polycystic ovarian syndrome (PCOS) C. Premature ovarian failure, decreased ovarian reserve, aneuploidy, and granulosa steroidogenesis D. Reproductive tract anomalies E. Uterine leiomyomas F. Endometriosis IV. Endocrine Disruptors, Mammary Gland Development, and Breast Cancer A. Windows of vulnerability to carcinogenic agents and "natural" risk factors B. Theories of carcinogenesis C. Susceptibility of the breast during puberty and adulthood D. Susceptibility of the mammary gland during the perinatal period E. Perinatal exposure to environmentally relevant levels of endocrine disruptors V. Male Reproductive and Developmental Health: The Human Evidence A. Introduction to male reproductive health B. Male reproductive function and development C. Semen quality: temporal trends and EDC exposure D. Male urogenital tract malformations E. Testicular germ cell cancer F. Conclusions VI. Prostate Cancer A. Introduction to prostate cancer B. Evidence and mechanisms for EDC effects on the prostate VII. Neuroendocrine Targets of EDCs A. Endocrine disruption of reproductive neuroendocrine systems B. Hypothalamic-pituitary-adrenal (HPA) effects of EDCs C. Thyroid, metabolism, and growth D. Hormonal targets of neuroendocrine disruption VIII. Thyroid Disruption A. Introduction to thyroid systems B. Environmental chemicals impacting thyroid function C. Environmental chemicals impacting thyroid hormone transport, metabolism, and clearance D. Environmental chemicals impacting the thyroid hormone receptor IX. Environmental Chemicals, Obesity, and Metabolism A. Introduction to EDCs and the obesity epidemic B. Environmental estrogens and obesity C. Peroxisome proliferator-activated receptor (PPAR) γ and organotins D. Phytoestrogens E. Endocrine disruptors, diabetes, and glucose homeostasis F. Endocrine disruptors and cardiovascular systems G. Estrogenic EDCs and cardioprotection H. Advanced glycation end-products (AGEs)
Endocr Rev. 2009 Jun; 30(4): 293–342.doi: 10.1210/er.2009-0002PMCID: PMC2726844PMID: 19502515Endocrine-Disrupting Chemicals: An Endocrine Society Scientific StatementEvanthia Diamanti-Kandarakis, Jean-Pierre Bourguignon, Linda C. Giudice, Russ Hauser, Gail S. Prins, Ana M. Soto, R. Thomas Zoeller, and Andrea C. GoreAuthor information Article notes Copyright and License information DisclaimerEndocrine Section of First Department of Medicine (E.D.-K.), Laiko Hospital, Medical School University of Athens,...
Αλέξανδρος Γ. Σφακιανάκης
2h
The Heterogeneous Landscape of Head & Neck Squamous Cell Carcinomas, Head & Neck Squamous Cell...
The Heterogeneous Landscape of Head & Neck Squamous Cell Carcinomas,Head & Neck Squamous Cell CarcinomasHead and neck squamous cell carcinomas can be highly aggressive tumors in some cases, while other prognoses can be very good. The tumors present in different anatomical regions of the upper airways and digestive tract, and they present with very different mutation profiles, molecular characteristics, and immune landscapes, as well as prognoses.Recognizing that differences in these head...
Αλέξανδρος Γ. Σφακιανάκης
2h
Oncology
The Heterogeneous Landscape of Head & Neck Squamous Cell CarcinomasNo abstract availableFinding a Cure for Children With CNS NeuroblastomaNo abstract availableEHR Tool Finds Pediatric Leukemia Patients for Clinical StudiesNo abstract availableIn Search of an Immunotherapy Innovation for Ovarian CancerNo abstract availableChildhood Leukemia Cannot Hide From Immune SystemNo abstract availableUpToDate®No abstract availableEnzalutamide Improved Survival in Metastatic Prostate CancerNo abstract availableOlaparib...
Αλέξανδρος Γ. Σφακιανάκης
2h
Surgical Laparoscopy Endoscopy & Percutaneous Techniques
Endoscopic Transgastric Versus Surgical Approach for Infected Necrotizing Pancreatitis: A Systematic Review and Meta-AnalysisSurgical approach (SA) is the standard treatment for infected necrotizing pancreatitis (INP) and endoscopic transgastric approach (ETA) is a promising alternative treatment. This systematic review and meta-analysis aimed to compare the effectiveness and safety of ETA versus SA in INP. Several databases were systematically searched for eligible studies that compared ETA with...
Αλέξανδρος Γ. Σφακιανάκης
2h
Endoscopic Transgastric Versus Surgical Approach for Infected Necrotizing Pancreatitis: A Systematic...
Endoscopic Transgastric Versus Surgical Approach for Infected Necrotizing Pancreatitis: A Systematic Review and Meta-AnalysisSurgical approach (SA) is the standard treatment for infected necrotizing pancreatitis (INP) and endoscopic transgastric approach (ETA) is a promising alternative treatment. This systematic review and meta-analysis aimed to compare the effectiveness and safety of ETA versus SA in INP. Several databases were systematically searched for eligible studies that compared ETA with...
Αλέξανδρος Γ. Σφακιανάκης
2h
Offline beats online: transcranial direct current stimulation timing influences on working memory The...
Offline beats online: transcranial direct current stimulation timing influences on working memoryThe n-back task is an established measure of an individual's working memory. In this task, participants have to continuously update their working memory to react to a stimulus correctly. For the verbal n-back task in particular, the left dorsolateral prefrontal cortex (lDLPFC) plays a key role in working memory updating and a higher activation of the lDLPFC has been linked to an increase in performance....
Αλέξανδρος Γ. Σφακιανάκης
2h
Gastroenterology & Hepatology
Norfloxacin, ciprofloxacin, trimethoprim–sulfamethoxazole, and rifaximin for the prevention of spontaneous bacterial peritonitis: a network meta-analysisFor the prevention of spontaneous bacterial peritonitis (SBP) in cirrhotic patients with ascites, prophylactic antibiotics are recommended as a standard regimen. This study aimed to assess the efficacy of norfloxacin (N), ciprofloxacin (C), trimethoprim–sulfamethoxazole (T-S), and rifaximin (R) in the prevention of SBP. We searched the electronic...
Αλέξανδρος Γ. Σφακιανάκης
2h
Norfloxacin, ciprofloxacin, trimethoprim–sulfamethoxazole, and rifaximin for the prevention of spontaneous...
Norfloxacin, ciprofloxacin, trimethoprim–sulfamethoxazole, and rifaximin for the prevention of spontaneous bacterial peritonitis: a network meta-analysisFor the prevention of spontaneous bacterial peritonitis (SBP) in cirrhotic patients with ascites, prophylactic antibiotics are recommended as a standard regimen. This study aimed to assess the efficacy of norfloxacin (N), ciprofloxacin (C), trimethoprim–sulfamethoxazole (T-S), and rifaximin (R) in the prevention of SBP. We searched the electronic...
Αλέξανδρος Γ. Σφακιανάκης
2h
Epidemiology
Sponsorship by Big Oil, Like the Tobacco Industry, Should be Banned by the Research CommunityNo abstract availableFine Particulate Air Pollution and Birthweight: Differences in Associations Along the Birthweight DistributionBackground: Maternal exposure to fine particulate air pollution (PM2.5) during pregnancy is associated with lower newborn birthweight, which is a risk factor for chronic disease. Existing studies typically report the average association related with PM2.5 increase, which does...
Αλέξανδρος Γ. Σφακιανάκης
2h
Gadolinium-Based MRI Contrast Agents Induce Mitochondrial Toxicity and Cell Death in Human Neurons,...
Gadolinium-Based MRI Contrast Agents Induce Mitochondrial Toxicity and Cell Death in Human Neurons, and Toxicity Increases With Reduced Kinetic Stability of the AgentObjectives This preclinical study was devised to investigate potential cellular toxicity in human neurons induced by gadolinium-based contrast agents (GBCAs) used for contrast-enhanced magnetic resonance imaging (MRI). Neurons modeling a subset of those in the basal ganglia were tested, because the basal ganglia region is 1 of 2 brain...
Αλέξανδρος Γ. Σφακιανάκης
2h
Sponsorship by Big Oil, Like the Tobacco Industry, Should be Banned by the Research Community No abstract...
Sponsorship by Big Oil, Like the Tobacco Industry, Should be Banned by the Research CommunityNo abstract availableFine Particulate Air Pollution and Birthweight: Differences in Associations Along the Birthweight DistributionBackground: Maternal exposure to fine particulate air pollution (PM2.5) during pregnancy is associated with lower newborn birthweight, which is a risk factor for chronic disease. Existing studies typically report the average association related with PM2.5 increase, which does...
Αλέξανδρος Γ. Σφακιανάκης
2h
Infectious Disease  A Summary of Recently Published Activity PERSPECTIVE Health Care Autonomy...
Infectious Disease A Summary of Recently Published ActivityPERSPECTIVEHealth Care Autonomy of Women Living with HIVR.R. Redfield and OthersN Engl J Med, July 24, 2019Imaging an Outbreak — Ultrasound in an Ebola Treatment UnitP.C. HenwoodN Engl J Med 381:6, July 4, 2019ORIGINAL ARTICLEDolutegravir plus Two Different Prodrugs of Tenofovir to Treat HIVW.D.F. Venter and OthersN Engl J Med, July 24, 2019Dolutegravir-Based or Low-Dose Efavirenz–Based Regimen for the Treatment of HIV-1The NAMSAL ANRS 12313...
Αλέξανδρος Γ. Σφακιανάκης
2h

Coronary Artery Disease
Beneficial effect of ticagrelor on microvascular perfusion in patients with ST-segment elevation myocardial infarction undergoing a primary percutaneous coronary interventionBackground Ticagrelor significantly reduced the incidence of death, myocardial infarction, and stent thrombosis in patients with ST-segment elevation myocardial infarction (STEMI) intended for reperfusion with a primary percutaneous coronary intervention (pPCI). However, the effects of this drug on microvascular perfusion in...
Αλέξανδρος Γ. Σφακιανάκης
2h
Association between lactic acid sting test scores, self‐assessed sensitive skin scores and biophysical...
Association between lactic acid sting test scores, self‐assessed sensitive skin scores and biophysical properties in Chinese femalesD.‐M. Ding, Y. Tu, M.‐Q. Man, W.‐J. Wu, F.‐Y. Lu, X. Li, Y. Li, J.‐T. Yang, Y.‐M. Jin, C.‐Y. Yang, L. HeVersion of Record online: 31 July 2019Renewable sources: Applications in personal care formulations  Fotini Μellou, Athanasia Varvaresou, Spyridon PapageorgiouFirst Published: 01 August 2019
Αλέξανδρος Γ. Σφακιανάκης
2h
Beneficial effect of ticagrelor on microvascular perfusion in patients with ST-segment elevation myocardial...
Beneficial effect of ticagrelor on microvascular perfusion in patients with ST-segment elevation myocardial infarction undergoing a primary percutaneous coronary interventionBackground Ticagrelor significantly reduced the incidence of death, myocardial infarction, and stent thrombosis in patients with ST-segment elevation myocardial infarction (STEMI) intended for reperfusion with a primary percutaneous coronary intervention (pPCI). However, the effects of this drug on microvascular perfusion in...
Αλέξανδρος Γ. Σφακιανάκης
2h
The antibody response in HIV-1-infected donors Purpose of review Although the goal of preventive HIV...
The antibody response in HIV-1-infected donorsPurpose of review Although the goal of preventive HIV vaccine design is primarily the induction of broadly neutralizing antibodies (bNAbs), recent evidence suggests that a protective response will also benefit from Fc effector functions. Here, we provide an update on the antibody response to HIV infection, including both Fab and Fc-mediated antibody responses. We also highlight recent studies showing the interplay between these functions, focusing primarily...
Αλέξανδρος Γ. Σφακιανάκης
2h

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