Πέμπτη, 11 Απριλίου 2019

Cancer Oncology


NASA Twins Study offers new insight on how a human's body responds to spaceflight
(Colorado State University) Colorado State University Professor Susan Bailey, who studies telomeres, or the protective 'caps' on the ends of chromosomes, found that Scott Kelly's telomeres in his white blood cells got longer while in space. Changes in telomere length could mean a person is at risk for accelerated aging or the diseases that come along with getting older. (Source: EurekAlert! - Cancer)
MedWorm Cancer & Oncology News
Thu Apr 11, 2019 06:00
Shutting down deadly pediatric brain cancer at its earliest moments
(Cincinnati Children's Hospital Medical Center) Cell-by-cell genetic analyses of developing brain tissues in neonatal mice and laboratory models of brain cancer allowed scientists to discover a molecular driver of the highly aggressive, deadly, and treatment-resistant brain cancer, glioblastoma. Published in Cell Stem Cell, the findings present an opportunity to find out if new therapeutic approaches can stop glioblastoma at its earliest stages of initial formation or recurrence. (Source: EurekAlert!...
MedWorm Cancer & Oncology News
Thu Apr 11, 2019 06:00
Maintenance immunotherapy fails to improve survival in extensive small cell lung cancer
(European Society for Medical Oncology) Maintenance immunotherapy fails to improve survival in extensive-stage small cell lung cancer (SCLC), according to late-breaking results from the CheckMate 451 study to be presented today at the European Lung Cancer Congress (ELCC) 2019. (Source: EurekAlert! - Cancer)
MedWorm Cancer & Oncology News
Thu Apr 11, 2019 06:00
Discovery of 'kingpin' stem cell may help in the understanding of cancerous tumors
(McMaster University) Bhatia's team spent more than six years delving down to the cellular level to examine what they say are previously overlooked cells that form on the edges of pluripotent stem cell colonies. Having characterized these cells, the team also observed them form at the earliest stages of pluripotent cell reprogramming from adult cells. (Source: EurekAlert! - Cancer)
MedWorm Cancer & Oncology News
Thu Apr 11, 2019 06:00
Lots of patients with cancer, cancer survivors use but don't report complementary/alternative medicine therapies
This study used data from a nationwide survey to estimate how many patients with cancer and cancer survivors use complementary and alternative medicines (CAMS) in addition to or instead of conventional therapies, and how many don't disclose that to their physicians. (Source: EurekAlert! - Cancer)MedWorm Message: If you are looking to buy something in the January Sales please visit TheJanuarySales.com for a directory of all the best sales in the UK. Any income gained via affiliate links keeps MedWorm...
MedWorm Cancer & Oncology News
Thu Apr 11, 2019 06:00
Medicaid reimbursement to treat cancer patients with radiation therapy varies widely
(American Society for Radiation Oncology) A new study finds wide state-by-state variations in Medicaid reimbursements to physicians who treat cancer patients with radiation therapies. These differences could compound existing disparities in access to health care in rural communities, which tend to have higher Medicaid coverage rates than metropolitan areas. The study is available for free access through April 24 in the International Journal of Radiation Oncology * Biology * Physics (Red Journal)....
MedWorm Cancer & Oncology News
Thu Apr 11, 2019 06:00
'Nanobodies' from alpacas could help bring CAR T-cell therapy to solid tumors
(Boston Children's Hospital) Most CAR T-cell therapies look for antigens specific to cancer cells. A new approach described in this week's PNAS instead targets the environment around the tumor, using unusually small antibodies made naturally by alpacas, camels and llamas. Using this approach in mouse models, investigators successfully curbed melanoma and colon cancer - solid tumors that currently can't be treated with CAR T-cell therapy. (Source: EurekAlert! - Cancer)
MedWorm Cancer & Oncology News
Thu Apr 11, 2019 06:00
One-third of cancer patients use complementary and alternative medicine
(UT Southwestern Medical Center) A stunning one-third of people with a cancer diagnosis use complementary and alternative medicines such as meditation, yoga, acupuncture, herbal medicine, and supplements. (Source: EurekAlert! - Cancer)
MedWorm Cancer & Oncology News
Thu Apr 11, 2019 06:00
Molecules that curb errant proteins of AL amyloidosis point to new type of therapy
(Scripps Research Institute) Scientists at Scripps Research have identified a group of small molecules that prevent structural changes to proteins that are at the root of AL amyloidosis, a progressive and often fatal disease. The drug mechanism that the team identified is analogous to a different drug that also originated at Scripps Research: Tafamidis, which stabilizes the protein transthyretin to treat the most common systemic amyloid disease that affects the heart or other organs. (Source: EurekAlert!...
MedWorm Cancer & Oncology News
Thu Apr 11, 2019 06:00
Many Cancer Patients Take Alternative Meds But Don't Tell Their Doctors
(Source: Cancercompass News: Other Cancer)
MedWorm Cancer & Oncology News
Thu Apr 11, 2019 02:00
Sunscreen's Secret Bonus: It Could Help Keep You Cool
(Source: Cancercompass News: Other Cancer)
MedWorm Cancer & Oncology News
Thu Apr 11, 2019 02:00
Give Detroit Challenge 2019
(Source: Karmanos Cancer Institute)
MedWorm Cancer & Oncology News
Wed Apr 10, 2019 15:45
Loss of a DNA repair system creates a unique vulnerability in many cancer types
(Broad Institute of MIT and Harvard) Cancer cells adapt to potentially fatal mutations and other molecular malfunctions by adjusting one or more other genes' activity, in the process becoming dependent on those genes for their survival and growth. The resulting genetic dependencies may provide targets for developing new precision-guided drugs or other cancer treatment strategies.Reporting in Nature, researchers describe one such vulnerability shared by a large subset of colon, gastric, endometrial,...
MedWorm Cancer & Oncology News
Wed Apr 10, 2019 06:00
Already regretting hiring Cormac McCarthy to revise the script for Star Wars Ep. IX - Boing Boing
Already regretting hiring Cormac McCarthy to revise the script for Star Wars Ep. IX  Boing BoingPreviously: Already regretting assigning J.G. Ballard to cover the Fyre Festival Already regretting assigning the new MacBook Pro review to Borges Already ...
Cancer of Tongue - Google News
04:27
A Direct Podocalyxin-Dynamin-2 Interaction Regulates Cytoskeletal Dynamics to Promote Migration and Metastasis in Pancreatic Cancer Cells
The sialoglycoprotein podocalyxin is absent in normal pancreas but is overexpressed in pancreatic cancer and is associated with poor clinical outcome. Here we investigate the role of podocalyxin in migration and metastasis of pancreatic adenocarcinomas using SW1990 and Pa03c as cell models. Although ezrin is regarded as a cytoplasmic binding partner of podocalyxin that regulates actin polymerization via Rac1 or RhoA, we did not detect podocalyxin-ezrin association in pancreatic cancer cells. Moreover,...
Cancer Research Online First Articles
Thu Apr 11, 2019 17:16
Rising horizon in circumventing multidrug resistance in chemotherapy with nanotechnology
Publication date: August 2019Source: Materials Science and Engineering: C, Volume 101Author(s): Hira Choudhury, Manisha Pandey, Tan Hui Yin, Taasjir Kaur, Gan Wei Jia, S.Q. Lawrence Tan, How Weijie, Eric Koh Sze Yang, Chin Guan Keat, Subrat Kumar Bhattamishra, Prashant Kesharwani, Shadab Md, Nagasekhara Molugulu, Mallikarjuna Rao Pichika, Bapi GorainAbstractMultidrug resistance (MDR) is one of the key barriers in chemotherapy, leading to the generation of insensitive cancer cells towards administered...
MedWorm Cancer & Oncology Research
02:08
Magnetic and self-healing chitosan-alginate hydrogel encapsulated gelatin microspheres via covalent cross-linking for drug delivery
Publication date: August 2019Source: Materials Science and Engineering: C, Volume 101Author(s): Xueyun Chen, Ming Fan, Huaping Tan, Bowen Ren, Guoliang Yuan, Yang Jia, Jianliang Li, Dangsheng Xiong, Xiaodong Xing, Xiaohong Niu, Xiaohong HuAbstractIn order to broaden the abilities of injectable hydrogel scaffolds, a self-healing chitosan/alginate hydrogel encapsulated with magnetic gelatin microspheres (MGMs) was prepared for anti-cancer drug delivery and soft tissue engineering. The hydrogel was...
MedWorm Cancer & Oncology Research
02:08

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