Παρασκευή 23 Φεβρουαρίου 2018

Deciphering the roles of FOXO1 in human neoplasms

Abstract

Neoplasms constitute an enormous burden and contributed to an estimated 8.2 million deaths in 2012 worldwide. FOXO1 (forkhead box O1), a member of the forkhead box (FOX) family, is a transcriptional factor involved in diverse cellular functions. Herein, we concentrate on recent studies of the antineoplastic roles of FOXO1 in neoplasms. This review may serve as a guide for future research and identify FOXO1 as a potent therapeutic target in neoplasms. This article is protected by copyright. All rights reserved.



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