AIMS: Reusing insulin pen needles could help to reduce the increasing economic burden of diabetes. We tested the hypothesis that reusing insulin pen needles leads to needle tip deformity and increased pain. METHODS: Three blinded reviewers assessed 123 electron microscope pictures analyzing needle tip deformity of insulin pen needles used up to four times by diabetic subjects and up to five times by blinded non-diabetic volunteers. The estimated frequency of needle use was correlated to the actual number of needle use. Pain intensity and unpleasantness of each injection were measured by a visual analogue scale and their differences analyzed by Kruskal-Wallis analysis of variance. RESULTS: Unused needles could be differentiated visually from used needles. However, there was no correlation between the actual and guessed number of times a needle was used (r = 0.07, P = 0.2). Evaluating all 270 injections, neither pain intensity nor unpleasantness increased with repeated injections of the same needles in people with diabetes (P = 0.1 and 0.96) and in the volunteers (P = 0.63 and 0.92). CONCLUSIONS: Using pen needles four to five times does not lead to progressive needle tip deformity and does not increase pain intensity or unpleasantness, but could increase convenience and lead to substantial financial savings in Europe of around EUR 100 million/year.
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from #AlexandrosSfakianakis via Alexandros G.Sfakianakis on Inoreader http://ift.tt/2oLOayI via IFTTT
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Publication date: 18 April 2017 Source: Cell Reports, Volume 19, Issue 3 Author(s): David Estoppey, Chia Min Lee, Marco Janoschke, Boon He...
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Abstract Functionalised electrospun polyamide-6 (PA-6) nanofibres incorporating gadolinium oxide nanoparticles conjugated to zinc tetracar...
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Cytokine-dependent renewal of stem cells is a fundamental requisite for tissue homeostasis and regeneration. Spermatogonial progenitor cells...
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Yahoo Health Ken Brookes Lost 102 Pounds: 'I Never Want to Go Back to Being Unhealthy' Yahoo Health My wife died of ovarian ...
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Own a website? Manage your page to keep your users updated View some of our premium pages: . . . . Upgrade to a Premium Page from #Alexand...
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Radiation Research, Volume 187, Issue 6 , Page 647-658, June 2017. from #AlexandrosSfakianakis via Alexandros G.Sfakianakis on Inoreader ...
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Abstract Background Cells in the intervertebral disc have unique phenotypes and marker genes that separate the nucleus pulposus (NP), an...
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Publication date: Available online 23 February 2017 Source: Journal of Biomechanics Author(s): Lipika Parida, Udita Uday Ghosh, Venkat Pad...
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