Τρίτη 17 Ιανουαρίου 2017

Tryptase-catalyzed core histone truncation: a novel epigenetic regulatory mechanism in mast cells

Tryptase is mainly implicated in events downstream of mast cell degranulation. Here we show that tryptase additionally has a role in intranuclear core histone processing, thereby affecting epigenetic regulation and cellular differentiation in mast cells.

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