Τρίτη 10 Ιανουαρίου 2017

Ohr plays a central role in bacterial responses against fatty acid hydroperoxides and peroxynitrite [Biochemistry]

Organic hydroperoxide resistance (Ohr) enzymes are unique Cys-based, lipoyl-dependent peroxidases. Here, we investigated the involvement of Ohr in bacterial responses toward distinct hydroperoxides. In silico results indicated that fatty acid (but not cholesterol) hydroperoxides docked well into the active site of Ohr from Xylella fastidiosa and were efficiently reduced by...

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