Pedunculated carcinoma ex pleomorphic adenoma of the nasal cavity: A unique case report.

Pedunculated carcinoma ex pleomorphic adenoma of the nasal cavity: A unique case report.

Medicine (Baltimore). 2016 Sep;95(39):e5004

Authors: Liao PW, Chen YL, Chen JW

Abstract
BACKGROUND: A carcinoma ex pleomorphic adenoma (CXPA) is an epithelial malignancy arising in or from a benign pleomorphic salivary adenoma. The parotid gland is the most common location of CXPAs. Minor salivary gland CXPAs of the nasal cavity are exceedingly rare, with only 6 documented in the literature.
METHODS AND RESULT: We present a 7th case: an unusual pedunculated intranasal CXPA, which had a favorable outcome after a wide endoscopic excision and the longest follow-up period reported to date. The clinical features, immunohistochemical characteristics, treatment choices, and disease outcomes of the intranasal CXPAs reported in previous studies are also reviewed.
CONCLUSION: This case demonstrates the importance of considering the possibility of CXPA in the differential diagnosis of minor salivary gland malignancies in the nasal cavity.

PMID: 27684860 [PubMed - as supplied by publisher]

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