Πέμπτη, 1 Αυγούστου 2019

Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,00306932607174,alsfakia@gmail.com,


MDPI
IJERPH, Vol. 16, Pages 2745: Vulnerable Populations Exposed to Lead-Contaminated Drinking Water within Houston Ship Channel CommunitiesIJERPH, Vol. 16, Pages 2745: Vulnerable Populations Exposed to Lead-Contaminated Drinking Water within Houston Ship Channel Communities International Journal of Environmental Research and Public Health doi: 10.3390/ijerph16152745 Authors: Garett Sansom Leslie Cizmas Kathleen Aarvig Benika Dixon Katie R. Kirsch Anjali Katare Lindsay Sansom Recent events have drawn...
Αλέξανδρος Γ. Σφακιανάκης
6m
Viruses, Vol. 11, Pages 701: Metagenomic Next-Generation Sequencing Reveal Presence of a Novel...
Viruses, Vol. 11, Pages 701: Metagenomic Next-Generation Sequencing Reveal Presence of a Novel Ungulate Bocaparvovirus in AlpacasViruses, Vol. 11, Pages 701: Metagenomic Next-Generation Sequencing Reveal Presence of a Novel Ungulate Bocaparvovirus in Alpacas Viruses doi: 10.3390/v11080701 Authors: Kumar Chaudhary Lu Duff Heffel McKinney Bedenice Marthaler Viruses belonging to the genus Bocaparvovirus (BoV) are a genetically diverse group of DNA viruses known to cause respiratory, enteric, and neurological...
Αλέξανδρος Γ. Σφακιανάκης
38m
Vaccines, Vol. 7, Pages 77: Nanobodies that Neutralize HIV Vaccines, Vol. 7, Pages 77: Nanobodies...
Vaccines, Vol. 7, Pages 77: Nanobodies that Neutralize HIVVaccines, Vol. 7, Pages 77: Nanobodies that Neutralize HIV Vaccines doi: 10.3390/vaccines7030077 Authors: Weiss Verrips Nanobodies or VHH (variable domains of heavy-chain only antibodies) are derived from camelid species such as llamas and camels. Nanobodies isolated and selected through phage display can neutralize a broad range of human immunodeficiency virus type 1 (HIV-1) strains. Nanobodies fit into canyons on the HIV envelope that may...
Αλέξανδρος Γ. Σφακιανάκης
38m
Antibiotic and Pesticides Residues in Breast Milk
Toxics, Vol. 7, Pages 39: Assessment of Antibiotic and Pesticides Residues in Breast Milk of Syrian Refugee Lactating MothersNadia Smadi 1,†, Adla Jammoul 2,† and Nada El Darra 1,*1Faculty of Heath Sciences, Beirut Arab University, Tarik El Jedidah–Beirut, P.O.Box: 115020, Riad EL Solh, Beirut 1107 2809, Lebanon2Food Department, Lebanese Agricultural Research Institute, Fanar P.O. Box 2611, Beirut 1107 2809, Lebanon*Author to whom correspondence should be addressed.†These authors contributed equally.Toxics...
Αλέξανδρος Γ. Σφακιανάκης
42m
Social Sciences, Vol. 8, Pages 229: The Street-Wise University: The Amsterdam Knowledge Mile as an Intermediary...
Social Sciences, Vol. 8, Pages 229: The Street-Wise University: The Amsterdam Knowledge Mile as an Intermediary and Place-Making ConceptSocial Sciences, Vol. 8, Pages 229: The Street-Wise University: The Amsterdam Knowledge Mile as an Intermediary and Place-Making Concept Social Sciences doi: 10.3390/socsci8080229 Authors: van Winden Hagemans van Hemert Universities have become more engaged or entrepreneurial, forging deeper relations with society beyond the economic sphere. To foster, structure,...
Αλέξανδρος Γ. Σφακιανάκης
43m
Psych, Vol. 1, Pages 429-430: Expression of Concern: Lynn, R. Reflections on Sixty-Eight Years of Research...
Psych, Vol. 1, Pages 429-430: Expression of Concern: Lynn, R. Reflections on Sixty-Eight Years of Research on Race and Intelligence. Psych, 2019, 1, 123–131Psych, Vol. 1, Pages 429-430: Expression of Concern: Lynn, R. Reflections on Sixty-Eight Years of Research on Race and Intelligence. Psych, 2019, 1, 123–131 Psych doi: 10.3390/psych1010033 Authors: Psych Editorial Office The Editorial Office of Psych issues the following Expression of Concern about the published paper: Reflections on Sixty-Eight...
Αλέξανδρος Γ. Σφακιανάκης
44m
Microorganisms, Vol. 7, Pages 230: Contrast of Real-Time Fluorescent PCR Methods for Detection...
Microorganisms, Vol. 7, Pages 230: Contrast of Real-Time Fluorescent PCR Methods for Detection of Escherichia coli O157:H7 and of Introducing an Internal Amplification ControlMicroorganisms, Vol. 7, Pages 230: Contrast of Real-Time Fluorescent PCR Methods for Detection of Escherichia coli O157:H7 and of Introducing an Internal Amplification Control Microorganisms doi: 10.3390/microorganisms7080230 Authors: Zhao Xia Liu Various constituents in food specimens can inhibit the PCR assay and lead to false-negative...
Αλέξανδρος Γ. Σφακιανάκης
44m
Medicina, Vol. 55, Pages 423: Handheld Ultrasound and Focused Cardiovascular Echography: Use and...
Medicina, Vol. 55, Pages 423: Handheld Ultrasound and Focused Cardiovascular Echography: Use and InformationMedicina, Vol. 55, Pages 423: Handheld Ultrasound and Focused Cardiovascular Echography: Use and Information Medicina doi: 10.3390/medicina55080423 Authors: Savino Ambrosio The availability of miniaturized ultrasound machines has changed our approach to many cardiovascular diseases. Handheld ultrasound imaging can be performed at the bedside, it is easy to use, and the information provided,...
Αλέξανδρος Γ. Σφακιανάκης
45m
JCM, Vol. 8, Pages 1144: Shock Index Predicts Outcome in Patients with Suspected Sepsis or Community-Acquired...
JCM, Vol. 8, Pages 1144: Shock Index Predicts Outcome in Patients with Suspected Sepsis or Community-Acquired Pneumonia: A Systematic ReviewJCM, Vol. 8, Pages 1144: Shock Index Predicts Outcome in Patients with Suspected Sepsis or Community-Acquired Pneumonia: A Systematic Review Journal of Clinical Medicine doi: 10.3390/jcm8081144 Authors: Middleton Smith Bedford Neilly Myint Background: To improve outcomes for patients who present to hospital with suspected sepsis, it is necessary to accurately...
Αλέξανδρος Γ. Σφακιανάκης
45m
Humanities, Vol. 8, Pages 130: The Composite Nature of Andreas Humanities, Vol. 8, Pages 130:...
Humanities, Vol. 8, Pages 130: The Composite Nature of AndreasHumanities, Vol. 8, Pages 130: The Composite Nature of Andreas Humanities doi: 10.3390/h8030130 Authors: Maddock Scholars of the Old English poem Andreas have long debated its dating and authorship, as the poem shares affinities both with Beowulf and the signed poems of Cynewulf. Although this debate hinges on poetic style and other internal evidence, the stylistic uniformity of Andreas has not been suitably demonstrated. This paper investigates...
Αλέξανδρος Γ. Σφακιανάκης
46m
Children, Vol. 6, Pages 89: Emerging Topics in Cardiometabolic and Psychologic Sequelae, Pathogenesis,...
Children, Vol. 6, Pages 89: Emerging Topics in Cardiometabolic and Psychologic Sequelae, Pathogenesis, and Treatment of Polycystic Ovarian Syndrome: A ReviewChildren, Vol. 6, Pages 89: Emerging Topics in Cardiometabolic and Psychologic Sequelae, Pathogenesis, and Treatment of Polycystic Ovarian Syndrome: A Review Children doi: 10.3390/children6080089 Authors: Shah Polycystic ovarian syndrome (PCOS) is a common endocrine disorder, affecting 6–10% of reproductive age women and influences the reproductive,...
Αλέξανδρος Γ. Σφακιανάκης
46m
Cancers, Vol. 11, Pages 1091: Glioblastoma: State of the Art and Future Perspectives Cancers,...
Cancers, Vol. 11, Pages 1091: Glioblastoma: State of the Art and Future PerspectivesCancers, Vol. 11, Pages 1091: Glioblastoma: State of the Art and Future Perspectives Cancers doi: 10.3390/cancers11081091 Authors: Tabatabai Wakimoto This special issue is dedicated to glioblastoma and elucidates this disease from differentperspectives [...]CancersWed Jul 31, 2019 03:00Cancers, Vol. 11, Pages 1092: Combination of Whole-Brain Radiotherapy with Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitors...
Αλέξανδρος Γ. Σφακιανάκης
47m
Impact of skeletal muscle mass volume on surgical site infection in free flap reconstruction for oral...
Impact of skeletal muscle mass volume on surgical site infection in free flap reconstruction for oral cancerTakaya Makiguchi MD, PhD  Takahiro Yamaguchi DDS  Hideharu Nakamura MD  Keisuke Suzuki DDS Norifumi Harimoto MD, PhD  Ken Shirabe MD, PhD  Satoshi Yokoo DMD, DMScFirst published: 22 July 2019 https://doi.org/10.1002/micr.30494Read the full textePDFPDFTOOLS SHAREAbstractBackgroundSarcopenia is a disease in which skeletal muscle mass (SMM) and function are progressively lost. Here, we investigate...
Αλέξανδρος Γ. Σφακιανάκης
48m
A method using the cephalic vein for superdrainage in breast reconstruction Hideki Tokumoto MD, PhD ...
A method using the cephalic vein for superdrainage in breast reconstructionHideki Tokumoto MD, PhD  Shinsuke Akita MD, PhD  Minami Arai MD  Yoshitaka Kubota MD, PhD Motone Kuriyama MD, PhD  Nobuyuki Mitsukawa MD, PhDFirst published: 22 July 2019 https://doi.org/10.1002/micr.30489Read the full textePDFPDFTOOLS SHAREAbstractBackgroundIn breast reconstruction, a superdrainage procedure using the superficial inferior epigastric vein has been described. The purpose of this study was to investigate whether...
Αλέξανδρος Γ. Σφακιανάκης
49m
Direct muscle neurotization with long acellular nerve allograft: A case report Sami H. Tuffaha MD ...
Direct muscle neurotization with long acellular nerve allograft: A case reportSami H. Tuffaha MD  Jesse D. Meaike MD  Steven L. Moran MDFirst published: 22 July 2019 https://doi.org/10.1002/micr.30498Read the full textePDFPDFTOOLS SHAREAbstractNerve repair and nerve transfer are the optimal approaches to restore function to denervated muscle. When the distal‐most portion of the nerve entering the muscle is compromised, these are not possible and direct muscle neurotization (DMN) is considered. We...
Αλέξανδρος Γ. Σφακιανάκης
49m
Allergy, Asthma , Immunology
Management of Asthma COPD OverlapPublication date: Available online 31 July 2019Source: Annals of Allergy, Asthma & ImmunologyAuthor(s): Diego Jose Maselli, Nicola Alexander HananiaDrug reaction with eosinophilia and systemic symptoms (DRESS) and cytomegalovirus colitisPublication date: Available online 31 July 2019Source: Annals of Allergy, Asthma & ImmunologyAuthor(s): Dr Matthew Krummenacher, Dr Tatjana Banovic, Dr Frank Kette, Dr William Smith, Dr Pravin HissariaCharacterization of Idiopathic...
Αλέξανδρος Γ. Σφακιανάκης
49m
CranioMaxillofacial Surgery
Simultaneous endoscopic endonasal sinus surgery and sinus augmentation with immediate implant placement: A retrospective clinical study of 23 patientsPublication date: August 2019Source: Journal of Cranio-Maxillofacial Surgery, Volume 47, Issue 8Author(s): Levon Khachatryan, Grigor Khachatryan, Gagik Hakobyan, Anna KhachatryanAbstractObjectiveThe aim of this study was to evaluate the efficacy of simultaneous endoscopic endonasal sinus surgery and sinus augmentation with immediate implant placement.Patients...
Αλέξανδρος Γ. Σφακιανάκης
51m
Neuroradiology/Head and Neck Imaging Original ResearchArterial Spin-Labeling MRI Identifies Hypervascular...
Neuroradiology/Head and Neck ImagingOriginal ResearchArterial Spin-Labeling MRI Identifies Hypervascular MeningiomasVera Mayercik, et al. | American Journal of Roentgenology | Jul 30, 2019Ahead of PrintCardiopulmonary ImagingReviewA Radiologist's Guide to the Changing Treatment Paradigm of Advanced Non–Small Cell Lung Cancer: The ASCO 2018 Molecular Testing Guidelines and Targeted TherapiesLydia Chen, et al. | American Journal of Roentgenology | Jul 30, 2019Ahead of PrintNuclear Medicine and Molecular...
Αλέξανδρος Γ. Σφακιανάκης
51m
Systems approach reveals photosensitivity and PER2 level as determinants of clock‐modulator efficacyDae...
Systems approach reveals photosensitivity and PER2 level as determinants of clock‐modulator efficacyDae Wook Kim, Cheng Chang, Xian Chen, Angela C Doran, Francois Gaudreault, Travis Wager, George J DeMarco, Jae Kyoung Kime8838 | First Published: 08 July 2019 The study identifies the sources of the inter‐ and intraspecies variability in the modulation of circadian phase by CK1δ/ε inhibition: photosensitivity and PER2 abundance, and proposes a personalized chronotherapy to treat circadian disruption.
Αλέξανδρος Γ. Σφακιανάκης
52m
NeuroOncology
A review of eligibility for patients with central nervous system (CNS) metastases from non-small cell lung cancer (NSCLC) in immunotherapy clinical trialsCentral nervous system neuroblastoma metastases pseudoprogression following intraventricular anti-B7-H3 radioimmunotherapyA novel finding of an IDH2 mutation in an interesting adult Sonic Hedgehog mutated medulloblastomaPrognostic significance of VEGF receptors expression on the tumor cells in skull base chordomaAbstractBackgroundChordoma is a rare...
Αλέξανδρος Γ. Σφακιανάκης
54m
Griseofulvin versus Terbinafine for pediatric Tinea Capitis: when and for how long Jonathan Bar  Liat...
Griseofulvin versus Terbinafine for pediatric Tinea Capitis: when and for how longJonathan Bar  Liat Samuelov  Eli Sprecher  Jacob MashiahFirst published: 25 July 2019 https://doi.org/10.1111/myc.12970This article has been accepted for publication and undergone full peer review but has not been through the copyediting, typesetting, pagination and proofreading process, which may lead to differences between this version and the Version of Record. Please cite this article as doi: 10.1111/myc.12970ePDFPDFTOOLS...
Αλέξανδρος Γ. Σφακιανάκης
55m
Identification of Cryptococcus Antigen in HIV‐positive Turkish Patients by Using the Dynamiker® Lateral...
Identification of Cryptococcus Antigen in HIV‐positive Turkish Patients by Using the Dynamiker® Lateral Flow AssayEvrim Karaman  Macit Ilkit  Ferit KuşçuFirst published: 25 July 2019 https://doi.org/10.1111/myc.12969This article has been accepted for publication and undergone full peer review but has not been through the copyediting, typesetting, pagination and proofreading process, which may lead to differences between this version and the Version of Record. Please cite this article as doi:10.1111/myc.12969ePDFPDFTOOLS...
Αλέξανδρος Γ. Σφακιανάκης
55m
Epidemiology and Management Burden of Invasive Fungal Infections after Autologous Hematopoietic Stem...
Epidemiology and Management Burden of Invasive Fungal Infections after Autologous Hematopoietic Stem Cell Transplantation: 10‐Year Experience at a European Pediatric Cancer CenterChristina Linke  Athanasios Tragiannidis  Martina Ahlmann  Birgit Fröhlich  Maria Wältermann  Birgit Burkhardt  Claudia Rossig  Andreas H. GrollFirst published: 23 July 2019 https://doi.org/10.1111/myc.12968This article has been accepted for publication and undergone full peer review but has not been through the copyediting,...
Αλέξανδρος Γ. Σφακιανάκης
55m
Phaeohyphomycosis caused by Phialophora americana with CARD9 mutation and 20‐year literature review...
Phaeohyphomycosis caused by Phialophora americana with CARD9 mutation and 20‐year literature review in ChinaChen Huang  Yi Zhang  Yinggai Song  Zhe Wan  Xiaowen Wang  Ruoyu LiFirst published: 04 July 2019 https://doi.org/10.1111/myc.12962Read the full textePDFPDFTOOLS SHARESummaryBackgroundPhaeohyphomycosis is a chronic cutaneous, subcutaneous or systemic mycotic infection caused by various dematiaceous fungi. The diverse clinical manifestations and poor prognosis of phaeohyphomycosis necessitate...
Αλέξανδρος Γ. Σφακιανάκης
56m
Microsurgery Early View Online Version of Record before inclusion in an issue BOOK REVIEWSJoint Denervation:...
MicrosurgeryEarly ViewOnline Version of Record before inclusion in an issueBOOK REVIEWSJoint Denervation: Anatomic Atlas of Surgical Technique, Dellon, A. Lee Springer; 1st ed. 2019 edition (March 4, 2019), 277 pages, Price $134.62Zenggan Chen MD, PhD, Feng Zhang MD, PhDVersion of Record online: 22 July 2019CLINICAL ARTICLESImpact of skeletal muscle mass volume on surgical site infection in free flap reconstruction for oral cancerTakaya Makiguchi MD, PhD, Takahiro Yamaguchi DDS, Hideharu Nakamura...
Αλέξανδρος Γ. Σφακιανάκης
56m
Chondro-Osseous Respiratory Epithelial Adenomatoid Hamartoma (COREAH): Case Report and Literature...
Chondro-Osseous Respiratory Epithelial Adenomatoid Hamartoma (COREAH): Case Report and Literature ReviewAndrew Daniel, Eugene Wong, Joyce Ho, and Narinder SinghWestmead Hospital, Westmead, NSW, AustraliaCorrespondence should be addressed to Andrew Daniel; andrew.rms.daniel@gmail.comReceived 25 February 2019; Revised 28 April 2019; Accepted 3 July 2019; Published 25 July 2019Academic Editor: Kamal MorshedCopyright © 2019 Andrew Daniel et al. This is an open access article distributed under the Creative...
Αλέξανδρος Γ. Σφακιανάκης
59m
Otolaryngology
Thyroglossal Duct Cyst Carcinoma in a Young Female: Case Report and Review of LiteratureThyroglossal duct remnants form during embryologic development and can develop into a thyroglossal duct cyst (TGDC). In rare cases, carcinoma is present within these cysts, most commonly papillary thyroid carcinoma. Diagnosis is difficult, but imaging and fine-needle aspiration (FNA) biopsies can help with the diagnosis. Given the rarity of TGDC carcinoma, treatment is not well agreed upon and can include the...
Αλέξανδρος Γ. Σφακιανάκης
59m
Adult-Type Rhabdomyoma of the Omohyoid Muscle Brian H. Cameron,1 Kyle Hannabass,2 Anuradha Kanungo,3 and Dinesh...
Adult-Type Rhabdomyoma of the Omohyoid MuscleBrian H. Cameron,1 Kyle Hannabass,2 Anuradha Kanungo,3 and Dinesh K.Chhetri21Keck School of Medicine of USC, Los Angeles, CA, USA2Department of Head and Neck Surgery, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, CA, USA3Department of Pathology, Olive View-UCLA Medical Center, Los Angeles, CA, USACorrespondence should be addressed to Dinesh K. Chhetri; dchhetri@mednet.ucla.eduReceived 4 March 2019; Revised 12 June...
Αλέξανδρος Γ. Σφακιανάκης
1h
Thyroglossal Duct Cyst Carcinoma in a Young Female: Case Report and Review of Literature Jenna Van...
Thyroglossal Duct Cyst Carcinoma in a Young Female: Case Report and Review of LiteratureJenna Van Beck and Sobia F. KhajaDepartment of Otolaryngology-Head and Neck Surgery, University of Minnesota, Minneapolis, MN, USACorrespondence should be addressed to Jenna Van Beck; vanb0092@umn.eduReceived 8 May 2019; Accepted 22 July 2019; Published 31 July 2019Academic Editor: Manish GuptaCopyright © 2019 Jenna Van Beck and Sobia F. Khaja. This is an open access article distributed under the Creative Commons...
Αλέξανδρος Γ. Σφακιανάκης
1h
Case Reports in Otolaryngology Volume 2019, Article ID 3725720, 5 pages https://doi.org/10.1155/2019/3725720...
Case Reports in OtolaryngologyVolume 2019, Article ID 3725720, 5 pageshttps://doi.org/10.1155/2019/3725720Case ReportA Case Report of Aggressive Chronic Rhinosinusitis with Nasal Polyps Mimicking Sinonasal MalignancyS. Velegrakis, N. Chatzakis, E. Prokopakis, M. Papadakis, E. Panagiotaki, M.Doulaptsi, and A. KaratzanisDepartment of Otorhinolaryngology, University of Crete School of Medicine, Heraklion, Crete, GreeceCorrespondence should be addressed to A. Karatzanis; akaratzanis@yahoo.comReceived...
Αλέξανδρος Γ. Σφακιανάκης
1h
Lung Perfusion Scintigraphy in Eisenmenger Syndrome Due to Patent Ductus Arteriosus Eisenmenger syndrome...
Lung Perfusion Scintigraphy in Eisenmenger Syndrome Due to Patent Ductus ArteriosusEisenmenger syndrome refers to the elevation of pulmonary arterial pressure to the systemic level caused by an increased pulmonary vascular resistance with right-to-left shunt through an intracardiac or aortopulmonary communication. A 36-year-old woman with Eisenmenger syndrome due to patent ductus arteriosus underwent 99mTc-MAA lung perfusion scintigraphy to evaluate right-to-left shunt. Whole-body imaging visualized...
Αλέξανδρος Γ. Σφακιανάκης
1h
Otology & Neurotology
Preclinical Validation of a Novel Device Designed to Reduce Biofilms on Percutaneous Osseointegrated AbutmentsAim: To assess the efficacy of a prototype cleaning device in removing biofilm from skin-penetrating abutments. Background: Adverse skin reactions around percutaneous osseointegrated implants have been linked to poor hygiene and infection. A cleaning device made from open-cell polyfoam has been developed to facilitate manual cleaning of abutments by the patient. Methods: Serratia biofilm...
Αλέξανδρος Γ. Σφακιανάκης
1h
Case Reports in Otolaryngology
A Case Report of Aggressive Chronic Rhinosinusitis with Nasal Polyps Mimicking Sinonasal Malignancy, S. Velegrakis, N. Chatzakis, E. Prokopakis, M. Papadakis, E. Panagiotaki, M. Doulaptsi, and A. KaratzanisVolume 2019 (2019), Article ID 3725720, 5 pagesA Case of Focal Dermal Hypoplasia (Goltze Syndrome) Masquerading as Lingual Tonsillar Hypertrophy, Samuel T. Roberts, Greg Shein, and Ian JacobsonVolume 2019 (2019), Article ID 9536256, 3 pagesFloppy Closing Door Epiglottis Treated Successfully with...
Αλέξανδρος Γ. Σφακιανάκης
1h
Hunger-Activated AgRP Neurons Inhibit MPOA Neurons Controlling Parenting Morgane Boillot The Journal...
Hunger-Activated AgRP Neurons Inhibit MPOA Neurons Controlling ParentingMorgane BoillotThe Journal of Neuroscience, 31 July 2019, 39(31):6032-6034; doi:10.1523/JNEUROSCI.0589-19.2019http://www.jneurosci.org/content/39/31/6032Toward a Multimodal Framework of Brainstem Pain-Modulation Circuits in MigraineJulio A. YanesThe Journal of Neuroscience, 31 July 2019, 39(31):6035-6037; doi:10.1523/JNEUROSCI.0301-19.2019http://www.jneurosci.org/content/39/31/6035Research ArticlesCellular/MolecularInorganic...
Αλέξανδρος Γ. Σφακιανάκης
1h
From Hybrid to TransplantsPublished on Jul 31, 2019A Japanese researcher may soon be developing rat...
From Hybrid to TransplantsPublished on Jul 31, 2019A Japanese researcher may soon be developing rat and mouse embryos with human cells as part of a plan to eventually develop organs for transplants, according to Nature News. Read more >Skipping the DelaysPublished on Jul 31, 2019Kentucky law enforcement officials are testing a rapid DNA analyzer in sexual assault cases, CNBC reports. Read more >Avoid the PredatorsPublished on Jul 31, 2019Three medical writing organizations warn about the harm...
Αλέξανδρος Γ. Σφακιανάκης
1h
Development of a delayed-release nutrient for appetite control in adults with obesity and type 2 diabetes
Do we need race-specific resting metabolic rate prediction equations?James Reneau, Brittaney Obi, Andrea Moosreiner & Srividya KidambiNutrition & Diabetes 2019 9: 10.1038/s41387-019-0087-8Abstract | Full TextDevelopment of a delayed-release nutrient for appetite control in adults with obesity and type 2 diabetes and initial clinical testing in a single dose randomized controlled trialE. Beale, E. Lim, H. Yassine, C. Azen & C. ChristopherNutrition & Diabetes 2019 9: 10.1038/s41387-019-0088-7Abstract | Full...
Αλέξανδρος Γ. Σφακιανάκης
1h
Neoadjuvant BRAF‐targeted therapy in regionally advanced and oligometastatic melanoma Zeynep Eroglu ...
Neoadjuvant BRAF‐targeted therapy in regionally advanced and oligometastatic melanomaZeynep Eroglu  Jennifer Eatrides  Syeda Mahrukh Hussnain Naqvi  Youngchul Kim  Jeani Rich  Nalan Akgul Babacan  Andrew S Brohl  Joseph Markowitz  Amod Sarnaik  Jonathan Zager … See all authorsFirst published: 22 July 2019 https://doi.org/10.1111/pcmr.12813This article has been accepted for publication and undergone full peer review but has not been through the copyediting, typesetting, pagination and proofreading...
Αλέξανδρος Γ. Σφακιανάκης
1h
Discoidin domain receptors: A promising target in melanoma Coralie Reger de Moura  Maxime Battistella ...
Discoidin domain receptors: A promising target in melanomaCoralie Reger de Moura  Maxime Battistella  Anjum Sohail  Anne Caudron  Jean Paul Feugeas  Marie‐Pierre Podgorniak  Cecile Pages  Sarra Mazouz Dorval  Oren Marco … See all authorsFirst published: 04 July 2019 https://doi.org/10.1111/pcmr.12809Coralie Reger de Moura and Maxime Battistella: co‐first authors.Rafael Fridman, Celeste Lebbé, Samia Mourah and Fanélie Jouenne contributed equally to this work: co‐last authors.Read the full textePDFPDFTOOLS...
Αλέξανδρος Γ. Σφακιανάκης
1h
Self-seeding circulating tumor cells promote the proliferation and metastasis of human osteosarcoma...
Self-seeding circulating tumor cells promote the proliferation and metastasis of human osteosarcoma by upregulating interleukin-8Tao Liu, Qiong Ma, Yinglong Zhang, Xin Wang, Kui Xu et al.Cell Death & Disease 2019 10: 10.1038/s41419-019-1795-7Abstract | Full TextGLI1 activation by non-classical pathway integrin αvβ3/ERK1/2 maintains stem cell-like phenotype of multicellular aggregates in gastric cancer peritoneal metastasisHui Dong, Hongchang Liu, Wen Zhou, Fan Zhang, Chuan Li et al.Cell Death...
Αλέξανδρος Γ. Σφακιανάκης
1h

Autosomal recessive hyper‐IgE syndrome successfully treated with hematopoietic stem cell transplantationJorge...
Autosomal recessive hyper‐IgE syndrome successfully treated with hematopoietic stem cell transplantationJorge Lopes MD, Diogo Teixeira MD, Cristina Sousa MD, Armando Baptista MD, Diana Moreira MD, Eduarda O. Ferreira MDVersion of Record online: 24 July 2019REVIEW ARTICLESThe infantile cutaneous microbiome: A reviewJennifer J. Schoch MD, Reesa L. Monir MD, Kerrie G. Satcher MD, Jessica Harris MD, Eric Triplett PhD, Josef Neu MDVersion of Record online: 23 July 2019ORIGINAL ARTICLESApple cider vinegar...
Αλέξανδρος Γ. Σφακιανάκης
1h
Improving Accuracy and Efficiency with Concurrent Use of Artificial Intelligence for Digital...
Improving Accuracy and Efficiency with Concurrent Use of Artificial Intelligence for Digital Breast Tomosynthesis Reading times were significantly reduced, and sensitivity, specificity, and recall rate improved in a nonclinical reader study when an artificial intelligence system was utilized concurrently with image interpretation for digital breast tomosynthesis.  Emily F. Conant, Alicia Y. Toledano... Jeffrey W. HoffmeisterUsing Time as a Measure of Impact for AI Systems: Implications in Breast...
Αλέξανδρος Γ. Σφακιανάκης
1h
Implementation and Validation of a Three-dimensional Cardiac Motion Estimation Network  ...
Implementation and Validation of a Three-dimensional Cardiac Motion Estimation Network A deep learning–based three-dimensional nonrigid body motion estimation technique based on cine MR images was implemented; the method was validated against five state-of-the-art nonrigid body registration methods by using several image and motion metrics.  Manuel A. Morales, David Izquierdo-Garcia... Ciprian Catana
Αλέξανδρος Γ. Σφακιανάκης
1h
Radiomics Model to Predict Early Progression of Nonmetastatic Nasopharyngeal Carcinoma after...
Radiomics Model to Predict Early Progression of Nonmetastatic Nasopharyngeal Carcinoma after Intensity Modulation Radiation Therapy: A Multicenter Study A machine-learning radiomic model based on pretreatment MRI findings has potential in the identification of patients with nonmetastatic nasopharyngeal carcinoma who are at risk for early disease progression after primary treatment.   Richard Du, Victor H. Lee... Varut Vardhanabhuti
Αλέξανδρος Γ. Σφακιανάκης
1h
Urinary Stone Detection on CT Images Using Deep Convolutional Neural Networks: Evaluation of...
Urinary Stone Detection on CT Images Using Deep Convolutional Neural Networks: Evaluation of Model Performance and Generalization A cascading convolutional neural network model, enriched with labeled CT images, detected the presence of urinary tract stones on unenhanced abdominopelvic CT scans with high accuracy.   Anushri Parakh, Hyunkwang Lee... Synho Do
Αλέξανδρος Γ. Σφακιανάκης
1h
Necrosis Rather Than Apoptosis is The Dominant form of Alveolar Epithelial Cell Death In Lipopolysaccharide-Induced...
Necrosis Rather Than Apoptosis is The Dominant form of Alveolar Epithelial Cell Death In Lipopolysaccharide-Induced Experimental Acute Respiratory Distress Syndrome ModelAlveolar epithelial cell (AEC) death, which is classified as apoptosis or necrosis, plays a critical role in the pathogenesis of acute respiratory distress syndrome (ARDS). In addition to apoptosis, some types of necrosis are known to be molecularly regulated, and both apoptosis and necrosis can be therapeutic targets for diseases....
Αλέξανδρος Γ. Σφακιανάκης
1h
  Magician's Corner: How to Start Learning about Deep Learning  Deep learning can be done with...
 Magician's Corner: How to Start Learning about Deep Learning Deep learning can be done with minimal hardware and software.  Bradley J. Erickson
Αλέξανδρος Γ. Σφακιανάκης
1h
Impact of Long Wavelength Ultraviolet A1 and Visible Light on Light‐Skinned Individuals Indermeet Kohli ...
Impact of Long Wavelength Ultraviolet A1 and Visible Light on Light‐Skinned IndividualsIndermeet Kohli  Raheel Zubair  Alexis B. Lyons  Amanda F. Nahhas  Taylor L. Braunberger  Mohsen Mokhtari  Eduardo Ruvolo  Henry W. Lim  Iltefat H. HamzaviFirst published: 25 July 2019 https://doi.org/10.1111/php.13143This article has been accepted for publication and undergone full peer review but has not been through the copyediting, typesetting, pagination and proofreading process, which may lead to differences...
Αλέξανδρος Γ. Σφακιανάκης
1h
Method for Measurements of Terrestrial Ultraviolet Radiation on Inclined Surfaces in Personal Dosimetry...
Method for Measurements of Terrestrial Ultraviolet Radiation on Inclined Surfaces in Personal Dosimetry Field Studies Elena Corradi, Katarzyna A Baczynska, Marco Morelii, Danilo Giulietti, Marina KhazovaVersion of Record online: 25 July 2019A hypothesis that UVR measured on a vertical plane in the north direction can be used in the UK as a proxy for diffuse radiation to derive three‐dimensional irradiance profile was tested against direct measurements and compared with models based on solar tracker...
Αλέξανδρος Γ. Σφακιανάκης
1h
 Predictive Laboratories, Preeclampsia Foundation Partner to ID Genetic Factors of ConditionPublished...
 Predictive Laboratories, Preeclampsia Foundation Partner to ID Genetic Factors of ConditionPublished on Jul 31, 2019 Finnish Exomes Yield New Trait, Disease Associations Involving Rare, Deleterious VariantsPublished on Jul 31, 2019 Natural Selection May Have Influenced Abundance of Neurons That Sense Certain OdorsPublished on Jul 31, 2019Featured in Depth Meridian Bioscience Dx Revenue Woes Likely to Continue Through 2020 Despite Promising Integration of GenePOCPublished on Jul 31, 2019 MIT Researchers...
Αλέξανδρος Γ. Σφακιανάκης
1h
Unusually complicated course of a common disease: challenges in managing pediatric HIV Publication date:...
Unusually complicated course of a common disease: challenges in managing pediatric HIVPublication date: Available online 15 July 2019Source: Medical Journal Armed Forces IndiaAuthor(s): Punam Bajracharya, Suprita Kalra, Gitanjali Jain, Amit SoodDoes pre-procedure ultrasound increase the success and safety of right internal jugular venous catheterization? An intervention studyPublication date: Available online 12 July 2019Source: Medical Journal Armed Forces IndiaAuthor(s): Vikrant Ghode, Naresh Dhawan,...
Αλέξανδρος Γ. Σφακιανάκης
1h
Guiding choices and opening doors: Mentoring revisited By Mike Taigman Mentorship comes full circle...
Guiding choices and opening doors: Mentoring revisitedBy Mike TaigmanMentorship comes full circle for EMS leader Mike Taigman, in collaborations in quality improvement and advancing EMS
Αλέξανδρος Γ. Σφακιανάκης
1h
Early Acid Suppression Therapy Exposure and Fracture in Young Children Laura Malchodi, Kari Wagner, Apryl Susi, Gregory Gorman, Elizabeth Hisle-Gorman...
Early Acid Suppression Therapy Exposure and Fracture in Young ChildrenLaura Malchodi, Kari Wagner, Apryl Susi, Gregory Gorman, Elizabeth Hisle-GormanPediatrics Jul 2019, 144 (1) e20182625; DOI: 10.1542/peds.2018-2625PPI use in infancy, alone or with H2RAs, is associated with fracture after 1 year of age. PDFAcellular Pertussis Vaccine Effectiveness Over TimeOusseny Zerbo, Joan Bartlett, Kristin Goddard, Bruce Fireman, Edwin Lewis, Nicola P.KleinPediatrics Jul 2019, 144 (1) e20183466; DOI: 10.1542/peds.2018-3466Compared...
Αλέξανδρος Γ. Σφακιανάκης
1h
Toppling the Ethical Balance — Health Care Refusal and the Trump Administration E. Sepper DOI: 10.1056/NEJMp1908839...
Toppling the Ethical Balance — Health Care Refusal and the Trump AdministrationE. SepperDOI: 10.1056/NEJMp1908839 | July 31, 2019Population and the Environment — Time for Another Contraception RevolutionD.J. AndersonN Engl J Med 2019;381:397-399Saving the Endangered Physician-Scientist — A Plan for Accelerating Medical BreakthroughsM.K. Jain and OthersN Engl J Med 2019;381:399-402Ghosts of Our Collective Subconscious — What Blackface in a Yearbook Photo Means for Medical EducationD.W. Paul, Jr.N...
Αλέξανδρος Γ. Σφακιανάκης
1h
Buried bumper syndrome (BBS) is one of the uncommon and late complications of percutaneous endoscopic gastrostomy (PEG) placement. It occurs when the internal bumper of the PEG tube erodes into the gastric wall and lodges itself between the gastric wall and skin.
Buried bumper syndrome: A complication of percutaneous endoscopic gastrostomyJiri Cyrany, Stanislav Rejchrt, [...], and Jan BuresAdditional article informationAbstractPercutaneous endoscopic gastrostomy (PEG) is a widely used method of nutrition delivery for patients with long-term insufficiency of oral intake. The PEG complication rate varies from 0.4% to 22.5% of cases, with minor complications being three times more frequent. Buried bumper syndrome (BBS) is a severe complication of this method,...
Αλέξανδρος Γ. Σφακιανάκης
1h
GASTROENTEROLOGY ENDOSCOPY: NOT JUST A PROCEDURAL FOCUS No abstract available An Intervention for Person-Centered...
GASTROENTEROLOGY ENDOSCOPY: NOT JUST A PROCEDURAL FOCUSNo abstract availableAn Intervention for Person-Centered Support in Irritable Bowel Syndrome: Development and Pilot StudyIrritable bowel syndrome is a common and often chronic functional bowel disorder that can cause severe disruption of daily functioning in those affected, with subsequent high healthcare utilization and work absenteeism. Nurses represent an underutilized group in the current management of irritable bowel syndrome. The aim of...
Αλέξανδρος Γ. Σφακιανάκης
1h
Health Physics
Measuring Workload With Paired DetectorsLinear accelerator workloads for each available photon energy are important quantities to know for radiation safety considerations, and presented is a technique to measure the workload using paired detectors. The signals from the two detectors can give sufficient information to separate the signal contributions from 6 and 18 MV photon fields and, combined with a signal-per-monitor-unit calibration factor, yields the number of monitor units delivered for each...
Αλέξανδρος Γ. Σφακιανάκης
1h
Techniques in Shoulder & Elbow Surgery
Treatment of Sagittal Split Olecranon Fractures Using Dorsal Plates Combined With Tension Band Wiring or Cerclage WiresWe evaluated the results of olecranon fractures with an intra-articular sagittal plane fracture treated by dorsal plates in combination with tension band wiring or cerclage wires. We included patients with comminuted olecranon fractures with sagittal split treated with combination fixation. Postoperative functional assessment, Mayo Elbow Performance Score (MEPS) and complications...
Αλέξανδρος Γ. Σφακιανάκης
1h
Primer on Precision Medicine for Complex Chronic Disorders Precision medicine promises patients with...
Primer on Precision Medicine for Complex Chronic DisordersPrecision medicine promises patients with complex disorders the right treatment for the right patient at the right dose at the right time with expectation of better health at a lower cost. The demand for precision medicine highlights the limitations of modern Western medicine. Modern Western medicine is a population-based, top-down approach that uses pathology to define disease. Precision medicine is a bottom-up approach that identifies predisease...
Αλέξανδρος Γ. Σφακιανάκης
1h
Clinical and Translational Gastroenterology
Primer on Precision Medicine for Complex Chronic DisordersPrecision medicine promises patients with complex disorders the right treatment for the right patient at the right dose at the right time with expectation of better health at a lower cost. The demand for precision medicine highlights the limitations of modern Western medicine. Modern Western medicine is a population-based, top-down approach that uses pathology to define disease. Precision medicine is a bottom-up approach that identifies predisease...
Αλέξανδρος Γ. Σφακιανάκης
1h

Technological Pedagogical and Content Knowledge Among Medical Educators: What Is Our Readiness to Teach...
Technological Pedagogical and Content Knowledge Among Medical Educators: What Is Our Readiness to Teach With Technology?Purpose: This study aimed to empirically assess medical educator knowledge of pedagogy and technology to inform the direction of medical school faculty development efforts. Method: The Technological Pedagogical and Content Knowledge framework (TPACK) survey is a validated instrument for understanding educators' knowledge of content (CK), pedagogy (PK) and technology (TK) in teaching....
Αλέξανδρος Γ. Σφακιανάκης
1h
Intraoperative Placement of Paravertebral Catheters to Manage Postoperative Pain in Opioid-Dependent...
Intraoperative Placement of Paravertebral Catheters to Manage Postoperative Pain in Opioid-Dependent Patients After Thoracolumbar Spine Fusion Surgery: A Case ReportWe introduce a regional technique that involves the intraoperative placement of bilateral paravertebral catheters under direct visualization. The patient had stage IV lung cancer and was on chronic oxycodone therapy. He presented with a T10 metastatic lesion, and underwent spinal decompression with T7–L1 fusion and T10 corpectomy. Before...
Αλέξανδρος Γ. Σφακιανάκης
1h
Heterogeneity of human pancreatic islet isolation around Europe: results of a survey study. Aim. Europe...
Heterogeneity of human pancreatic islet isolation around Europe: results of a survey study.Aim. Europe is currently the most active region in the field of pancreatic islet transplantation and many of the leading groups are actually achieving similar good outcomes. Further collaborative advances in the field require the standardization of islet cell product isolation processes and this work aimed to identify differences in the human pancreatic islet isolation processes within European countries. Methods....
Αλέξανδρος Γ. Σφακιανάκης
1h
Anaesthesia
Intraoperative Placement of Paravertebral Catheters to Manage Postoperative Pain in Opioid-Dependent Patients After Thoracolumbar Spine Fusion Surgery: A Case ReportWe introduce a regional technique that involves the intraoperative placement of bilateral paravertebral catheters under direct visualization. The patient had stage IV lung cancer and was on chronic oxycodone therapy. He presented with a T10 metastatic lesion, and underwent spinal decompression with T7–L1 fusion and T10 corpectomy. Before...
Αλέξανδρος Γ. Σφακιανάκης
1h
Academic Medicine
Recognizing and Eliminating Shame Culture in Health Professions EducationNo abstract availableApplying to Medical School as a DACA RecipientWhen I was 15 years old, I left home to enter a prep school in New Hampshire, and quickly went from being a top student at my inner-city public school to someone struggling to reach the middle of the class. My parents were convinced that my attending this school was an opportunity that would open doors to a world I could barely glimpse at home. But during those...
Αλέξανδρος Γ. Σφακιανάκης
2h
Menopause
Sexual pain in the menopausal patient: individualizing treatment still bestNo abstract availableUnderstanding the unmet sexual health needs of women with breast cancerNo abstract availableVaginal laser treatment—first, do no harmNo abstract availableSexual frequency and pain in a randomized clinical trial of vaginal estradiol tablets, moisturizer, and placebo in postmenopausal womenObjective: To evaluate the efficacy of two common interventions for bothersome postmenopausal vaginal symptoms on improving...
Αλέξανδρος Γ. Σφακιανάκης
2h
Clinical Orthopaedics and Related Research(R)
Editorial: What Do You Say When a Patient Says Thank You?No abstract availableEditor's Spotlight/Take 5: What Role Does Positive Psychology Play in Understanding Pain Intensity and Disability Among Patients with Hand and Upper-extremity Conditions?No abstract availableWhat Role Does Positive Psychology Play in Understanding Pain Intensity and Disability Among Patients with Hand and Upper Extremity Conditions?Background A large body of research shows that psychologic distress and ineffective coping...
Αλέξανδρος Γ. Σφακιανάκης
2h
pH-sensitive anti-CTLA4 antibodies: yes to efficacy, no to toxicity Amnon Altman & Kok-Fai Kong ...
pH-sensitive anti-CTLA4 antibodies: yes to efficacy, no to toxicityAmnon Altman & Kok-Fai Kong Cell Research 2019 29 :601 - 602; July 12, 2019; 10.1038/s41422-019-0198-8Abstract | Full TextMicrobiota guides insulin trafficking in beta cellsOzren Stojanović & Mirko Trajkovski Cell Research 2019 29 :603 - 604; July 02, 2019; 10.1038/s41422-019-0200-5Abstract | Full TextCrystallizing BubR1's kinase activityJazeel F. Limzerwala & Jan M. van Deursen Cell Research 2019 29 :605 - 606; June 28,...
Αλέξανδρος Γ. Σφακιανάκης
2h
Therapeutics
https://sfakianakisorl.blogspot.com/2019/07/american-journal-of-therapeutics.htmlAlexandros SfakianakisAnapafseos 5 . Agios NikolaosCrete.Greece.7210028410261826948891480alsfakia@gmail.com
Αλέξανδρος Γ. Σφακιανάκης
2h
"Use of Raman spectroscopy in the assessment of skin after CO2 ablative fractional laser surgery on...
"Use of Raman spectroscopy in the assessment of skin after CO2 ablative fractional laser surgery on acne scars"Ivan A. Bratchenko, Lyudmila A. Bratchenko, Dmitry N. Artemyev, Yulia A. KhristoforovaVersion of Record online: 25 July 2019LETTERS TO THE EDITORInfrared thermography and color Doppler: Two combined tools for assessing inflammation in hidradenitis suppurativaGianluca Nazzaro, Chiara Moltrasio, Angelo V. MarzanoVersion of Record online: 24 July 2019ORIGINAL ARTICLESConfocal laser scanning...
Αλέξανδρος Γ. Σφακιανάκης
2h
American Journal of Therapeutics
Deprescription of Antihypertensive Medication in Aging: A Debatable IssueRituximab to Treat Fibrosing Mediastinitis–Associated Recurrent HemoptysisVancomycin-Associated Erythema MultiformeTopical Administration of Amphotericin B as an Effective Adjuvant Treatment for a Deep Fungal Infection of Diabetic Foot InjuryPrevalence of Colorectal Neoplasms and Mortality in New Users of Low-Dose Aspirin With Lower Gastrointestinal BleedingBackground: Aspirin inhibits platelet function and may therefore accelerate...
Αλέξανδρος Γ. Σφακιανάκης
2h
FULL MOON > AUGUST - We have the Algonquin Indians and giant prehistoric fish to thank for August's Full Moon name. The Algonquin have made their home around the North American Great Lakes since after the last ice age. The ice age was a time of fantastical beasts - ferocious short-faced bears (about twice the size of today's grizzly) stalked elephant-sized woolly mammoths on the steppe. While the mammoths and bears have vanished, one prehistoric relic still remains hidden in the dark waters of the lakes.
August's full moon is called the Full Sturgeon Moon, after the primitive fish that used to be abundant in North America's lakes and rivers during the summer months. Having remained mostly unchanged since the earliest fossil records, sturgeons are ancient living fossils that can grow up until 3.5 meters long, or as long as two adult humans stacked on top of each other. Nowadays, however, it's almost impossible to see a sturgeon during the Full Sturgeon Moon. While they used to thrive, sturgeons are...
Αλέξανδρος Γ. Σφακιανάκης
2h
Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,00306932607174,alsfakia@gmail.com,
Injection laryngoplasty as adjunct treatment method for muscle tension dysphonia: Preliminary findings...Injection laryngoplasty as adjunct treatment method for muscle tension dysphonia: Preliminary findingsDaniel Novakovic FRACS, MBBS, MPH, BSc  Duong Duy Nguyen MD, PhD  Antonia Chacon BAppSc (SpPath) Hons, CPSP  Catherine Madill PhD, CPSPFirst published: 30 July 2019 https://doi.org/10.1002/lary.28205Editor's Note: This Manuscript was accepted for publication on July 9, 2019.Presented at the American...
Αλέξανδρος Γ. Σφακιανάκης
1d
Pediatric Radiology
Correction to: Plea for a standardized imaging approach to disorders of sex development in neonates: Consensus proposal from European Society of Paediatric Radiology task forceThe above article was published online with an incorrect author name.Physeal separation in pediatric osteomyelitisAbstractIn children, acute osteomyelitis, an infection of the bone, is most commonly hematogeneous in origin. Osteomyelitis is most often diagnosed with magnetic resonance imaging (MRI) and findings may include...
Αλέξανδρος Γ. Σφακιανάκης
1d
Obesity Surgery
Timing of Gestation After Laparoscopic Sleeve Gastrectomy (LSG): Does it Influence Obstetrical and Neonatal Outcomes of Pregnancies?Ivor Lewis Oesophagectomy for a Distal Adenocarcinoma of the Oesophagus 10 Years After Roux-en-Y Gastric Bypass (RYGB)Correction to: Longitudinal Impacts of Gastric Bypass Surgery on Pharmacodynamics and Pharmacokinetics of StatinsIn the original article the authors failed to include the following footnote:Christine Ren FieldingCorrection to: Incidence and Risk Factors...
Αλέξανδρος Γ. Σφακιανάκης
1d
Pediatric Orthopaedics
Bone maturation of MRI residual developmental dysplasia of the hip with discrepancy between osseous and cartilaginous acetabular indexQuality of spontaneous amelioration of residual developmental dysplasia of the hip (DDH) is nowadays not possible to predict. Normal age-related values of the osseous acetabular index (OAI), cartilaginous acetabular index and labral acetabular index have been established on MRI. In this study, MRI of dysplastic hips has been evaluated, and further osseous acetabular...
Αλέξανδρος Γ. Σφακιανάκης
1d
Rheumatology
Editorial introductionsNo abstract availableImplications of juvenile idiopathic arthritis genetic risk variants for disease pathogenesis and classificationPurpose of review We assess the implications of recent advances in the genetics of juvenile idiopathic arthritis (JIA) for the evolving understanding of inflammatory arthritis in children. Recent findings JIA exhibits prominent genetic associations with the human leukocyte antigen (HLA) region, extending perhaps surprisingly even to the hyperinflammatory...
Αλέξανδρος Γ. Σφακιανάκης
1d
Anaesthesiology
Analgesic efficacy of ultrasound-guided interscalene block vs. supraclavicular block for ambulatory arthroscopic rotator cuff repair: A randomised noninferiority studyBACKGROUND Ultrasound-guided interscalene block (ISB) is the reference technique for pain control after ambulatory upper limb surgery, but supraclavicular block (SCB) is an alternative. OBJECTIVES The aim of this study was to compare the efficacy of SCB vs. ISB in patients undergoing ambulatory arthroscopic rotator cuff repair (ARCR),...
Αλέξανδρος Γ. Σφακιανάκης
1d
Cardiovascular Medicine
Percutaneous coronary interventions for stable ischemic heart disease in ItalyAims Although the benefits of percutaneous coronary interventions (PCIs) in patients with stable chronic ischemic heart disease (SIHD) are controversial, a large number of PCIs are currently performed in SIHD patients, frequently after coronary angiography (ad-hoc procedures), without the use of fractional flow reserve (FFR) to identify patients most likely to benefit from PCI. Methods Assessment of regional variations...
Αλέξανδρος Γ. Σφακιανάκης
1d
Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,00306932607174,alsfakia@gmail.com,
MDPIMolbank, Vol. 2019, Article M1075: N-Benzo[c][1,2,5]thiazol-4-yl-3-trifluoromethylbenzamideMolbank, Vol. 2019, Article M1075: N-Benzo[c][1,2,5]thiazol-4-yl-3-trifluoromethylbenzamide Molbank doi: 10.3390/M1075 Authors: Hamad H. Al Mamari Nasser Al Awaimri Yousuf Al Lawati The title compound, N-benzo[c][1,2,5]thiazol-4-yl-3-trifluoromethylbenzamide (1) was synthesized by reacting 3-trifluoromethylbenzoyl chloride (4) and 4-aminobenzo[c][1,2,5]thiadiazole (5). The compound was characterized by...
Αλέξανδρος Γ. Σφακιανάκης
2d

Advances in Neonatal Care
Why does Joy at Work Matter?No abstract availableNoteworthy Professional NewsNo abstract availableJoin Our 35th Anniversary Celebration in SaNANNah This Fall!No abstract availableZAP-VAP: A Quality Improvement Initiative to Decrease Ventilator-Associated Pneumonia in the Neonatal Intensive Care Unit, 2012-2016Background: Ventilator-associated pneumonia (VAP) is the second most frequent hospital-acquired infection in neonatal intensive care units (NICUs) and significantly affects neonatal morbidity...
Αλέξανδρος Γ. Σφακιανάκης
2d
Trauma and Acute Care Surgery
Selective aortic arch perfusion with fresh whole blood or HBOC-201 reverses hemorrhage-induced traumatic cardiac arrest in a lethal model of noncompressible torso hemorrhageBACKGROUND Hemorrhage-induced traumatic cardiac arrest (HiTCA) has a dismal survival rate. Previous studies demonstrated selective aortic arch perfusion (SAAP) with fresh whole blood (FWB) improved the rate of return of spontaneous circulation (ROSC) after HiTCA, compared with resuscitative endovascular balloon occlusion of the...
Αλέξανδρος Γ. Σφακιανάκης
2d
Advanced Emergency Nursing
AAENP and ACEP: Cultivating InterprofessionalismNo abstract availableThe Modified Valsalva Maneuver for Reversion of Stable Supraventricular Tachycardia: Lessons Learned From the REVERT TrialThe REVERT trial was a randomized multicenter trial that investigated the efficacy of using a modified Valsalva maneuver for the reversion of stable supraventricular tachycardia back to a sinus rhythm. Although no improvement in discharge to home from the emergency department (ED) or ED length of stay was observed,...
Αλέξανδρος Γ. Σφακιανάκης
2d
Cancer Research and Clinical Oncology
Correction to: Neoadjuvant chemoradiotherapy delivered with helical tomotherapy under daily image guidance for rectal cancer patients: efficacy and safety in a large, multi-institutional seriesThe article "Neoadjuvant chemoradiotherapy delivered with helical tomotherapy under daily image guidance for rectal cancer patients: efficacy and safety in a large, multi-institutional series"Low number of intrafollicular T cells may predict favourable response to rituximab-based immuno-chemotherapy in advanced...
Αλέξανδρος Γ. Σφακιανάκης
2d
Endocrine
LncRNA MCM3AP-AS1 promotes proliferation and invasion through regulating miR-211-5p/SPARC axis in papillary thyroid cancerAbstractBackgroundLong non-coding RNAs (lncRNAs) are an emerging class of regulators in cancer. A lncRNA, MCM3AP-AS1, has been demonstrated as a versatile mediator in many cancers, except papillary thyroid cancer. The aim of this study is to investigate the role and mechanism of MCM3AP-AS1 in papillary thyroid cancer.MethodsQuantitative real-time PCR was used to assess the level...
Αλέξανδρος Γ. Σφακιανάκης
2d
Medicine by Alexandros G. Sfakianakis,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,00302841026182,00306932607174,alsfakia@gmail.com,
MDPIVaccines, Vol. 7, Pages 75: Why New Vaccines for the Control of Ectoparasite Vectors Have Not Been Registered and Commercialized?Vaccines, Vol. 7, Pages 75: Why New Vaccines for the Control of Ectoparasite Vectors Have Not Been Registered and Commercialized? Vaccines doi: 10.3390/vaccines7030075 Authors: José de la Fuente Agustín Estrada-Peña The prevention and control of vector-borne diseases is a priority for improving global health. Despite recent advances in the characterization of ectoparasite-host-pathogen...Medicine...
Αλέξανδρος Γ. Σφακιανάκης
3d
Hypertension
Association between invasively measured aortic pulse pressure and orthostatic hypotension in patients undergoing invasive coronary angiographyObjective: Underlying pathophysiology of orthostatic hypotension has been poorly understood. We hypothesized that aortic pulse pressure (APP) reflecting aortic stiffness may be involved in the development of orthostatic hypotension. Methods: A total of 200 patients (age 64.3 ± 10.9 years, 62.5% men) who underwent invasive coronary angiography (ICA) were prospectively...
Αλέξανδρος Γ. Σφακιανάκης
3d
Angiogenesis
A new prognostic model for survival in second line for metastatic renal cell carcinoma: development and external validationAbstractBackgroundIn patients with metastatic renal cell carcinoma (mRCC), the oncologic benefit of second-line treatment for high volume tumors or presence of more than five risk factors remain to be defined. Our aim was to develop and externally validate a new model most likely to correctly predict overall survival (OS) categories in second line.MethodmRCC patients treated...
Αλέξανδρος Γ. Σφακιανάκης
3d
Musculoskeletal Surgery
Minimally invasive plate osteosynthesis (MIPO) in AO/OTA type B displaced clavicle fracturesAbstractIntroductionOpen reduction and plate fixation is known to reduce chances of malunion and symptomatic nonunion in displaced middle-third clavicle fractures. However, this treatment modality is also associated with several complications, such as hardware irritation, numbness around the surgical scar, infection, nonunion and implant failure. The minimally invasive plate osteosynthesis (MIPO) technique...
Αλέξανδρος Γ. Σφακιανάκης
3d
Physiological Sciences
Thyroxin and calcitonin secretion into thyroid venous blood is regulated by pharyngeal mechanical stimulation in anesthetized ratsAbstractThe effects of the pharyngeal non-noxious mechanical stimulation on the secretion of immunoreactive thyroxin (iT4), immunoreactive calcitonin (iCT), and immunoreactive parathyroid hormone (iPTH) into thyroid venous blood were examined in anesthetized rats. Secretion rates of iT4, iCT, and iPTH were calculated from their concentration in thyroid venous plasma and...
Αλέξανδρος Γ. Σφακιανάκης
3d
Cardiology
Electrical Storm: Current Evidence, Clinical Implications, and Future PerspectivesAbstractPurpose of ReviewElectrical storm (ES) is a life-threatening medical emergency of repetitive episodes of sustained ventricular arrhythmias within a short period. Its occurrence is associated with poor short- and long-term survival, even in patients with implantable cardioverter defibrillators (ICD). Management of ES is challenging and mainly based on retrospective studies. This article reviews the existing literature...
Αλέξανδρος Γ. Σφακιανάκης
3d
Gastroenterology
Recurrence of hepatocellular carcinoma at the porta-hepatis following liver transplantation diagnosed on EUS-FNAAbstractHepatocellular carcinoma (HCC) is a potentially fatal complication of chronic liver disease. Liver transplantation is now the preferred treatment due to good outcomes. We present a unique case of recurrence of HCC at the porta hepatis four years after orthotopic liver transplantation diagnosed via endoscopic ultrasound-guided fine needle aspiration (EUS-FNA). Our report also highlights...
Αλέξανδρος Γ. Σφακιανάκης
3d

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