Κυριακή, 7 Απριλίου 2019

Allergy Immunology

Dual sublingual immunotherapy with Japanese Cedar Pollen droplets and House Dust Mite tablets
Publication date: Available online 5 April 2019Source: Allergology InternationalAuthor(s): Tomokazu Matsuoka, Satoshi Igarashi, Yuumi Kuroda, Chiharu Fukano, Kensuke Natsui, Katsuyo Doi-Ohashi, Keisuke Masuyama
Allergology International
Sat Apr 06, 2019 16:12
Potential risk factors of adverse reactions to nonionic contrast media in patients with underlying dermatological diseases: An 8-year retrospective survey
Publication date: Available online 4 April 2019Source: Allergology InternationalAuthor(s): Emi Nakauchi, Takeshi Fukumoto, Satoru Takahashi, Nobuyuki Horita, Masahiro Oka, Chikako Nishigori
Allergology International
Fri Apr 05, 2019 14:31
Food processing and Occupational Respiratory Allergy ‐ a EAACI Position Paper
AbstractOccupational exposure to foods is responsible for up to 25% of cases of occupational asthma and rhinitis. Animal and vegetable high‐molecular weight proteins present in aerosolized foods during food processing, additives, preservatives, antioxidants and food contaminants are the main inhalant allergen sources. Most agents typically cause IgE‐mediated allergic reactions, causing a distinct form of food allergy (Class 3 food allergy). The allergenicity of a food protein, allergen exposure...
Allergy
Sat Apr 06, 2019 21:58
Supporting allergen‐specific immunotherapy by inhibition of Janus kinases
AbstractAllergen‐specific immunotherapy (AIT) is the only disease‐modifying and curative treatment for allergic diseases. While in selected indications such as Hymenoptera venom allergy the curative success of AIT is impressingly high, in other disease manifestations it only reduces the symptoms to a certain extend in a fraction of patients. Key problems leading to a reduced efficacy of AIT seem to partly depend on local inflammatory processes that are not only causing side‐effects, but additionally...
Allergy
Sat Apr 06, 2019 19:59
Immunological methods for diagnosis and monitoring of IgE‐mediated allergy caused by industrial sensitizing agents (IMExAllergy)
AbstractIndustrial sensitizing agents (allergens) in living and working environments play an important role in eliciting type I allergic disorders including asthma and allergic rhinitis. Successful management of allergic diseases necessitates identifying their specific causes (i.e. identify the causative agent(s) and the route of contact to allergen: airborne, or skin contact) to avoid further exposure. Identification of sensitization by a sensitive and validated measurement of specific‐IgE...
Allergy
Sat Apr 06, 2019 19:59
Towards clinically applicable biomarkers for asthma – An EAACI position paper
AbstractInflammation, structural and functional abnormalities within the airways are key features of asthma. Although these processes are well‐documented, their expression varies across the heterogeneous spectrum of asthma. Type 2 inflammatory responses are characterized by increased levels of eosinophils, FeNO and type 2 cytokines in blood and/or airways. Presently, type 2 asthma is the best‐defined endotype, typically found in patients with allergic asthma, but surprisingly also in non‐allergic...
Allergy
Sat Apr 06, 2019 17:13
Comparison of allergic rhinitis outcomes of the Environmental Exposure Unit and Nasal Allergen Challenge Model
Publication date: Available online 6 April 2019Source: Annals of Allergy, Asthma & ImmunologyAuthor(s): Mark W. Tenn, Lisa M. Steacy, Daniel E. Adams, Terry J. Walker, Anne K. Ellis
Allergy
Sat Apr 06, 2019 12:18
The Development and Evaluation of Peer Food Allergy Education Videos for School- Age Youth
Publication date: Available online 6 April 2019Source: Annals of Allergy, Asthma & ImmunologyAuthor(s): Jialing Jiang, Joel Gallagher, Jolanta Szkodon, Maaria Syed, Karina Gobin, Ruchi Gupta, Lucy Bilaver
Allergy
Sat Apr 06, 2019 12:18
Improving Allergy Skin Testing Proficiency
Publication date: Available online 5 April 2019Source: Annals of Allergy, Asthma & ImmunologyAuthor(s): Rachna R. Dave, Catherine M. Hammond, Charles W. Stewart, D.Betty Lew
Allergy
Sat Apr 06, 2019 12:18
Development Of A Progesterone-Specific IgE Assay For Diagnosing Patients With Suspected Progestogen Hypersensitivity
Publication date: Available online 4 April 2019Source: Annals of Allergy, Asthma & ImmunologyAuthor(s): Debajyoti Ghosh, Jonathan Bernstein
Allergy
Fri Apr 05, 2019 13:23
Anti-Eosinophil Therapy is associated with Decreased Body Mass Index in Severe Asthmatics: a Preliminary Retrospective Analysis
Publication date: Available online 4 April 2019Source: Annals of Allergy, Asthma & ImmunologyAuthor(s): Merin Kuruvilla, Meera Patrawala, Joshua M. Levy, Jennifer Shih, Frances E. Lee
Allergy
Fri Apr 05, 2019 13:23
"Early Immunologic Changes During the Onset of Atopic Dermatitis"
Publication date: Available online 4 April 2019Source: Annals of Allergy, Asthma & ImmunologyAuthor(s): Patrick M. Brunner
Allergy
Fri Apr 05, 2019 13:23
Exploring Latent Classes to Identify Prenatal and Early-life Sources of Racial Disparities in Allergic Disease
Publication date: Available online 4 April 2019Source: Annals of Allergy, Asthma & ImmunologyAuthor(s): Ganesa Wegienka, Alexandra Sitarik, Albert M. Levin, Edward M. Zoratti, Dennis Ownby, Christine Cole Johnson, Suzanne Havstad
Allergy
Fri Apr 05, 2019 13:23
Pediatricians underestimate parent receptiveness to early peanut introduction
Publication date: Available online 4 April 2019Source: Annals of Allergy, Asthma & ImmunologyAuthor(s): Michelle Lai, Scott H. Sicherer
Allergy
Fri Apr 05, 2019 13:23
The 2018 pipeline of targeted therapies under clinical development for primary Sjögren's syndrome: A systematic review of trials
Publication date: Available online 6 April 2019Source: Autoimmunity ReviewsAuthor(s): Renaud Felten, Florence Scher, Jean Sibilia, Jacques-Eric Gottenberg, Laurent ArnaudAbstractTo date, no immunomodulatory drug has proved efficacious in primary Sjögren's syndrome (pSS). In pSS, difficulties in drug efficacy assessment is related to the large spectrum of clinical involvements (glandular/extraglandular involvement), to the lack of correlation between symptoms of dryness and glandular function assessed...
Autoimmunity Reviews
Sat Apr 06, 2019 16:43
Is there a possible correlation between antibodies against lipopolysaccharide, intestinal and blood-brain barrier proteins in IBD subjects?
Publication date: Available online 5 April 2019Source: Autoimmunity ReviewsAuthor(s): Aristo Vojdani
Autoimmunity Reviews
Sat Apr 06, 2019 16:43
Extracellular vesicles in autoimmune vasculitis - Little dirts light the fire in blood vessels
Publication date: Available online 5 April 2019Source: Autoimmunity ReviewsAuthor(s): Xiuhua Wu, Yu Liu, Wei Wei, Ming-Lin LiuAbstractSystemic vasculitis is diverse group of autoimmune disorders which are characterized by inflammation of blood vessel walls with deep aching and burning pain. Their underlying etiology and pathophysiology still remain poorly understood. Extracellular vesicles (EVs), including exosomes, microvesicles (MVs), and apoptotic bodies, are membrane vesicular structures that...
Autoimmunity Reviews
Sat Apr 06, 2019 16:43
Thyroid disorders in patients with systemic sclerosis: A systematic review and meta-analysis
Publication date: Available online 5 April 2019Source: Autoimmunity ReviewsAuthor(s): Qiuming Yao, Zhenyu Song, Bin Wang, Jin-an Zhang, Kaida Mu
Autoimmunity Reviews
Sat Apr 06, 2019 16:43
Systemic rheumatic diseases: From biological agents to small molecules
Publication date: Available online 5 April 2019Source: Autoimmunity ReviewsAuthor(s): Piercarlo Sarzi-Puttini, Angela Ceribelli, Daniela Marotto, Alberto Batticciotto, Fabiola AtzeniAbstractThe development of biologics and small oral molecules has recently changed the scenario of pharmacologic treatment of systemic rheumatic diseases and it has become a real revolution. These drugs have innovative mechanisms of action, based on the inhibition of specific molecular or cellular targets directly involved...
Autoimmunity Reviews
Sat Apr 06, 2019 16:43
Endothelial function features and properties of large vessel behavior in systemic autoimmune diseases: a cross-talk among cardiovascular disease risk factors
Publication date: Available online 5 April 2019Source: Autoimmunity ReviewsAuthor(s): Rafael Giovani Missé, Isabela Bruna Pires Borges, Samuel Katsuyuki Shinjo
Autoimmunity Reviews
Sat Apr 06, 2019 16:43
G-CSF-induced aortitis: Two cases and review of the literature
Publication date: Available online 5 April 2019Source: Autoimmunity ReviewsAuthor(s): Ioannis Parodis, Lara Dani, Antonella Notarnicola, Git Martenhed, Pontus Fernström, Alexios Matikas, Oscar P.B. WiklanderAbstractBackgroundFebrile neutropenia is generally recognised as a complication of myelosuppressive chemotherapy. Recombinant human granulocyte colony stimulating factor (G-CSF) is commonly used as primary or secondary prophylaxis to reduce the degree and duration of neutropenia in patients at...
Autoimmunity Reviews
Sat Apr 06, 2019 16:43
Autoimmune signatures for prediction and diagnosis of autoimmune diabetes in Kuwait
Publication date: Available online 5 April 2019Source: Autoimmunity ReviewsAuthor(s): Mohamed Jahromi, Fahd Al-Mulla, Ebaa Al-Ozairi
Autoimmunity Reviews
Sat Apr 06, 2019 16:43
Corticosteroids and immunosuppressive agents for idiopathic recurrent pericarditis
Publication date: Available online 5 April 2019Source: Autoimmunity ReviewsAuthor(s): Nathan Peiffer-Smadja, Fanny Domont, David Saadoun, Patrice CacoubAbstractRecurrent pericarditis is a frequent and troublesome complication of acute pericarditis. Aspirin or non-steroidal anti-inflammatory drugs (NSAIDs) and colchicine are the mainstay of therapy but few data is available on second-line treatment. We retrospectively analyzed 13 patients, 7 females (54%), median age 40 years, with a median of 4 (IQR...
Autoimmunity Reviews
Sat Apr 06, 2019 16:43
Emerging role of air pollution in autoimmune diseases
Publication date: Available online 5 April 2019Source: Autoimmunity ReviewsAuthor(s): Chan-Na Zhao, Zhiwei Xu, Guo-Cui Wu, Yan-Mei Mao, Li-Na Liu, Qian-Wu, Yi-Lin Dan, Sha-Sha Tao, Qin Zhang, Napoleon Bellua Sam, Yin-Guang Fan, Yan-Feng Zou, Dong-Qing Ye, Hai-Feng PanAbstractAutoimmune diseases (ADs) are a broad spectrum of disorders featured by the body's immune responses being directed against its own tissues, resulting in prolonged inflammation and subsequent tissue damage. Recently, the exposure...
Autoimmunity Reviews
Sat Apr 06, 2019 16:43
Diagnosis of gluten-related disorders: A new and challenging public health problem
Publication date: Available online 5 April 2019Source: Autoimmunity ReviewsAuthor(s): M. Lucia Sur, Loredana Dascăl, Genel Sur, Daniel G. Sur, Emanuela Floca, Cornel Aldea, Iulia Lupan, Gabriel Samasca
Autoimmunity Reviews
Sat Apr 06, 2019 16:43
Does intravenous immunoglobulin therapy in Guillain-Barré syndrome patients interfere with serological Zika detection?
Publication date: Available online 5 April 2019Source: Autoimmunity ReviewsAuthor(s): Anupama Karnam, Emmanuel Stephen-Victor, Mrinmoy Das, Laurent Magy, Jean-Michel Vallat, Francis Bolgert, Etienne Simon-Loriere, Srini V. Kaveri, Anavaj Sakuntabhai, Jagadeesh Bayry
Autoimmunity Reviews
Sat Apr 06, 2019 16:43
Anakinra in idiopathic recurrent pericarditis refractory to immunosuppressive therapy; a preliminary experience in seven patients
Publication date: Available online 5 April 2019Source: Autoimmunity ReviewsAuthor(s): Amir Dagan, Pnina Langevitz, Yehuda Shoenfeld, Ora ShovmanAbstractBackgroundApproximately 5% of idiopathic recurrent pericarditis (IRP) patients are refractory or intolerant to NSAIDs, Colchicine and corticosteroids. The empiric treatment approach for these patients includes immunosuppression with Azathioprine (AZA) or immunomodulation with intravenous human immunoglobulin (IVIG). We assessed the efficacy and safety...
Autoimmunity Reviews
Sat Apr 06, 2019 16:43
Amplifying the concept of psoriatic arthritis: The role of autoimmunity in systemic psoriatic disease
Publication date: Available online 5 April 2019Source: Autoimmunity ReviewsAuthor(s): Maria Sole Chimenti, Francesco Caso, Stefano Alivernini, Erica De Martino, Luisa Costa, Barbara Tolusso, Paola Triggianese, Paola Conigliaro, Elisa Gremese, Raffaele Scarpa, Roberto PerriconeAbstractPsoriatic arthritis (PsA) is a chronic inflammatory arthritis that may be present in near 30% of patients affected by psoriasis (PsO), clinically characterized by inflammation of periarticular (e.g., enthesis) and articular...
Autoimmunity Reviews
Sat Apr 06, 2019 16:43
Editorial introductions
No abstract available
Current Opinion in Allergy and Clinical Immunology - Published Ahead-of-Print
Thu Apr 04, 2019 03:00
Esophageal IgE, IgG4, and mucosal eosinophilia in individuals with dysphagia
BackgroundEosinophilic esophagitis (EoE) is an inflammatory disease of the esophagus, producing failure to thrive in infants and dysphagia with food impaction in older children and adults. Although most people with EoE manifest atopic/allergic disease, the specific allergens to which immunoglobulin E (IgE) is directed, if any, have not yet been characterized.MethodsMucosal brush biopsy (MBB) and solid tissue biopsy (STB) specimens were prospectively obtained from 25 individuals with dysphagia...
International Forum of Allergy & Rhinology
Fri Apr 05, 2019 11:24
Human BCR analysis of single-sorted, putative IgE+ memory B cells in food allergy
R. Jimenez-Saiz, Y. Ellenbogen and K. Bruton et al. developed a method to identify bona fide IgE+ MBCs in humans, demonstrated their extreme rarity in circulation and cautioned against the clinical utility of their assessment.
JACI (AOP)
Fri Apr 05, 2019 03:00
Fine particulate matter exposure during pregnancy and infancy periods and incident asthma
Both prenatal and postnatal exposures to PM2.5 were associated with the later development of asthma. The vulnerable time windows might be within early- and mid-gestation and the first year after birth.
JACI (AOP)
Fri Apr 05, 2019 03:00
Unneutral Neutrophils in Late Phase Allergic Reactions
JACI (AOP)
Fri Apr 05, 2019 03:00
Allogeneic Hematopoietic Stem Cell Transplant Outcomes for Patients with Dominant-Negative IKFZ1/IKAROS Mutations
Publication date: Available online 6 April 2019Source: Journal of Allergy and Clinical ImmunologyAuthor(s): Erinn S. Kellner, Christa Krupski, Hye Sun Kuehn, Sergio D. Rosenzweig, Nao Yoshida, Seiji Kojima, David Boutbol, Sylvain Latour, Vincent Barlogis, Claire Galambrun, Asbjørg Stray-Pedersen, Hans Christian Erichsen, Rebecca A. Marsh
Journal of Allergy and Clinical Immunology
Sun Apr 07, 2019 15:33
Human BCR analysis of single-sorted, putative IgE<sup>+</sup> memory B cells in food allergy
Publication date: Available online 5 April 2019Source: Journal of Allergy and Clinical ImmunologyAuthor(s): Rodrigo Jiménez-Saiz, Yosef Ellenbogen, Kelly Bruton, Paul Spill, Doron D. Sommer, Hermenio Lima, Susan Waserman, Sarita U. Patil, Wayne G. Shreffler, Manel Jordana
Journal of Allergy and Clinical Immunology
Sat Apr 06, 2019 13:37
The Skin as an Immune Organ: Tolerance Versus Effector Responses, and Applications to Food Allergy and Hypersensitivity Reactions
Publication date: Available online 5 April 2019Source: Journal of Allergy and Clinical ImmunologyAuthor(s): Emma Guttman-Yassky, Lisa Zhou, James KruegerAbstractSkin is replete with immune-competent cells that modulate signaling pathways to maintain a salubrious immunogenic/tolerogenic balance. This fertile immune environment plays a significant role in the development of allergic responses and sensitivities, but the mechanisms underlying these pathways have been underappreciated and underutilized...
Journal of Allergy and Clinical Immunology
Fri Apr 05, 2019 16:40

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