Πέμπτη, 24 Ιανουαρίου 2019

The Laryngoscope

Establishment and verification of a mouse model of nasal wound healing
Objectives Poor wound healing as reflected by the development of synechia and osteitis after endoscopic sinus surgery may trigger disease recurrence. Animal models provide insights into the pathogenesis of poor wound healing and may aid in the development of new therapeutics. Here, we established a mouse model of nasal wound healing and confirmed its utility. Study Design Animal study. Methods Unilateral intranasal wounds were induced using a small interdental brush in 6‐week‐old C57BL/6...
The Laryngoscope
4h
Taste disorders are partly genetically determined: Role of the TAS2R38 gene, a pilot study
Objectives/Hypothesis Taste sensitivity varies greatly among individuals influencing eating behavior and health, consequently the disorders of this sense can affect the quality of life. The ability to perceive the bitter of thiourea compounds, such as phenylthiocarbamide (PTC), has been largely reported as a marker of the general taste sensitivity, food preferences, and health. PTC sensitivity is mediated by the TAS2R38 receptor and its genetic common variants. We study the role of the TAS2R38 receptor...
The Laryngoscope
4h
Somatosensory evoked potential: Preventing brachial plexus injury in transaxillary robotic surgery
Objectives/Hypothesis The potential for brachial plexopathy due to arm positioning is a major concern regarding the robotic transaxillary approach. Intraoperative nerve monitoring via somatosensory evoked potential (SSEP) has been suggested to prevent such injury. In this study, we examined the use of SSEP in detecting imminent brachial plexus traction during robotic transaxillary thyroid and parathyroid surgery. Study Design Retrospective case series. Methods A analysis was performed...
The Laryngoscope
1d
Comparative Assessment of Drug‐Induced Sleep Endoscopy Scoring Systems in Pediatric Sleep Apnea
Objectives/Hypothesis A wide variety of drug‐induced sleep endoscopy (DISE) scoring systems has been used to evaluate sites of upper airway obstruction in children and adults; however, a universally accepted DISE scoring system dedicated to children has not been developed. We evaluated the utility of DISE scoring systems in the assessment of obstructive sleep apnea (OSA) using a single cohort of pediatric patients. Study Design Retrospective chart review. Methods The medical records...
The Laryngoscope
1d
Pediatric dysphagia: Is interarytenoid mucosal height significant?
Objectives The clinical significance of the interarytenoid mucosal height (IAMH) in pediatric dysphagia, ranging from normal anatomy to a laryngeal cleft, is unknown. This study seeks to evaluate a cohort of patients who underwent evaluation of their IAMH during microdirect laryngoscopy (MDL) for associations between IAMH and dysphagia as diagnosed on preoperative videofluoroscopic swallow study (VFSS). Methods A retrospective case series of 1,351 patients who underwent MDL between 2011 and...
The Laryngoscope
1d
Validation of the Chinese Velopharyngeal Insufficiency Effects on Life Outcomes Instrument
Objectives/Hypothesis To translate the Velopharyngeal Insufficiency Effects on Life Outcomes (VELO) instrument into Chinese and test its psychometric properties. Study Design Quality of life instrument translation and validation. Methods The original English version of the VELO instrument was translated into Mandarin, back‐translated, and adapted among the Chinese population, based on the standardized guidelines for the cross‐culture adaption process. Velopharyngeal insufficiency (VPI)...
The Laryngoscope
1d

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