Δευτέρα 12 Μαρτίου 2018

Evaluation of Safety, Efficacy and Clinical Outcome after Endovascular Treatment of Aneurysmal Subarachnoid Haemorrhage In Coil-First Setting A 10-Year Series from a Single Centre

Publication date: Available online 12 March 2018
Source:Journal of Neuroradiology
Author(s): Muhammad AlMatter, Pervinder Bhogal, Marta Aguilar Pérez, Victoria Hellstern, Hansjörg Bäzner, Oliver Ganslandt, Hans Henkes
IntroductionThe endovascular treatment (EVT) of ruptured cerebral aneurysms has been widely adopted after publication of the ISAT. In this study we sought to evaluate the safety and efficacy of the EVT for ruptured aneurysms based on 10-year series from a single centre with coil-first strategy.MethodsAll patients with aneurysmal subarachnoid haemorrhage (aSAH) treated between 2007 and 2016 were retrospectively reviewed and divided according to initial treatment into an EVT and a microsurgical clipping (MSC) group. Clinical and radiological findings at presentation, treatment modalities and any procedural complications were recorded. The angiographic and clinical outcome was compared between the two groups.Results587 patients with aSAH were reviewed (452 EVT, 135 MSC). There were no significant differences in mean age or the Hunt and Hess grades. Parenchymal haemorrhage (PH) was more frequent in the MSC. Procedure related complications of the acute treatment were recorded in 5.5% and 32% in the EVT and MSC, respectively. The rate of retreatment was 21.9% in the EVT and 5.9% in the MSC. Late rehaemorrhage was not observed in either group. There was no significant difference in the clinical outcome between the two treatment groups after adjustment of the other prognostic factors.ConclusionThe majority of ruptured intracranial aneurysms can be managed via an endovascular approach in the acute phase with excellent safety profile and good efficacy. Despite the high rate of reperfusion after primary endovascular approach, retreatment has a very low rate of complications and the rate of recurrent haemorrhage is very low.



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