JDB, Vol. 6, Pages 1: Modeling Alzheimer’s and Other Age Related Human Diseases in Embryonic Systems

JDB, Vol. 6, Pages 1: Modeling Alzheimer’s and Other Age Related Human Diseases in Embryonic Systems

Journal of Developmental Biology doi: 10.3390/jdb6010001

Authors: Chu Lim Ajay Mathuru

Modeling human disease in animals is an important strategy to discover potential methods of intervention. We suggest that there is much to be gained by employing a multi-model approach that takes advantage of different animal systems used in the laboratory simultaneously. We use the example of modeling Alzheimer’s disease in Drosophila melanogaster, Caenorhabditis elegans, and Danio rerio to illustrate how such an approach can be employed to investigate the pathophysiology of the disease.

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