Advanced head and neck squamous cell carcinoma (HNSCC) remains a therapeutic challenge due to the development of therapy resistance. Several studies have implicated the development of cancer stem cells as a possible mechanism for therapy resistance in HNSCC. Heat shock protein 90’s (Hsp90’s) molecular chaperone function is implicated in pathways of resistance in HNSCC. Therefore, in the present study, we investigated the efficacy of novel C-terminal Hsp90 inhibitors (KU711 and KU757) in targeting HNSCC cancer stem cells (CSCs).
from #AlexandrosSfakianakis via Alexandros G.Sfakianakis on Inoreader http://ift.tt/2zwU501
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A two-arm multicenter phase II trial of one cycle chemoselection split-dose docetaxel, cisplatin and 5-fluorouracil (TPF) induction che...
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Abstract Purpose Overcoming the flaws of current data management conditions in head and neck oncology could enable integrated informatio...
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Abstract Fetal alcohol spectrum disorder (FASD) is the principal preventable cause of mental retardation in the western countries resulting...
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Forbes Is There Any Effective Treatment For Stage Four Cancer? Forbes Is there any proper treatment for fourth stage cancer ? original...
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Differential Evolution Optimization of the SAR Distribution for Head and Neck Hyperthermia. IEEE Trans Biomed Eng. 2016 Nov 14;: Auth...
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Abstract Background The purpose of this study was to present our experience with retropharyngeal node reirradiation using highly conform...
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ACS Nano DOI: 10.1021/acsnano.6b04244 from #AlexandrosSfakianakis via Alexandros G.Sfakianakis on Inoreader http://ift.tt/2aOZU8w via...
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JOURNAL OF JAPAN SOCIETY FOR SAFETY ENGINEERING_1998_5 from #AlexandrosSfakianakis via Alexandros G.Sfakianakis on Inoreader http://ift.tt...
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