An 87-year-old woman was referred to our hospital with progressive dyspnoea on effort over the previous 2 weeks. She had been treated for rheumatoid arthritis with oral prednisolone (5 mg/day) and tacrolimus (2 mg/day). At her first visit, vital signs and physical examination were normal except for slight rhonchi in anterior lung fields. Chest radiograph showed slight cardiomegaly, but no abnormal lesions were noted in either lung (figure 1A). Echocardiography demonstrated no evidence of congestive heart failure. She was thus diagnosed with cough variant asthma and/or asthma, and treated with inhaled budesonide (400 µg/day). However, 10 days later, she returned to our hospital because of increasing dyspnoea. She had tachypnoea (30 breaths/min), and intermittent wheezes emerged in both the cervical (online ) and left tracheobronchial areas. Additionally, the left bronchovesicular sound (online ) apparently decreased than that of right tracheobronchial area (online ).
Figure 1
Chest radiograph taken at the...
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