Remarkable advances in cancer immunotherapy in recent years have led to paradigm shifts in oncology. The most noticeable results have been with T-cell-based therapies including immune checkpoint inhibitors (ICI), genetically engineered T-cells and bispecific antibodies (BsAb). T-cells represent a major class of cellular drugs in immunosurveillance and tumor eradication with exquisite specificity and long-term memory. However, during tumor equilibrium or progression, T-cells become exhausted or tolerized to tumor cells [1,2].
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Publication date: Available online 4 January 2018 Source: European Journal of Radiology Author(s): Peiyao Zhang, Jing Wang, Qin Xu, Zhen...
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