This review considers evidence suggesting that activation of the ionotropic purinergic receptor P2X7 (P2X7R) is a contributing factor in the growth of brain tumors. Importantly, expression of P2X7R may be upregulated in both glioma cells and in immune responding microglial cells with possible differential effects on tumor progression. The recruitment of immune cells into tumor regions may not only be involved in supporting an immunosuppressive environment aiding tumor growth but activated microglia could secrete inflammatory factors promoting neoangiogenesis in expanding tumors.
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A two-arm multicenter phase II trial of one cycle chemoselection split-dose docetaxel, cisplatin and 5-fluorouracil (TPF) induction che...
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Dental implants are now broadly used to replace missing teeth, and the presence of infectious complications is rising. Dental implant therap...
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Indications and extent of central neck dissection for papillary thyroid cancer: An American Head and Neck Society Consensus Statement. ...
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Abstract Purpose Accurate and real-time prediction of the lung and lung tumor deformation during respiration are important consideration...
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Abstract Purpose of Review Our goal is to summarize the airway disease literature since September 11, 2001 (9/11), focusing on studies pub...
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Treatment effectiveness holds considerable importance in the association between service quality and satisfaction in medical service studies...
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Therapeutic agents designed to stimulate the immune system are now cornerstones in the treatment of metastatic melanoma. These drugs promote...
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Coenzyme Q (CoQ) is a key component of the mitochondrial respiratory chain, but it also has several other functions in the cellular metaboli...
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