We thank Hervier et al1 for providing comments on our article2 characterizing natural killer (NK) cells in the human lung. Based on analysis of CD69 expression, our results suggest that most CD56bright NK cells are tissue-resident, whereas most CD56dim NK cells in the lung circulate.2 Our results also indicate that the total lung NK cell population is largely hypofunctional. Hervier et al1 regret the fact that we studied NK cell functionality only as a whole, that is, regardless of the cells' status as tissue-resident (CD69-expressing) or circulating.
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Πέμπτη 18 Μαΐου 2017
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Purpose: The MHC-unrestricted activity of cytokine-induced killer (CIK) cells against chemo-surviving melanoma cancer stem cells (mCSC) was...
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Publication date: 18 April 2017 Source: Cell Reports, Volume 19, Issue 3 Author(s): David Estoppey, Chia Min Lee, Marco Janoschke, Boon He...
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Abstract Functionalised electrospun polyamide-6 (PA-6) nanofibres incorporating gadolinium oxide nanoparticles conjugated to zinc tetracar...
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Cytokine-dependent renewal of stem cells is a fundamental requisite for tissue homeostasis and regeneration. Spermatogonial progenitor cells...
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Abstract This paper addresses the hybrid consensus-based formation keeping problem for nonholonomic mobile robots in the presence of a nov...
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Current treatments for generalized pustular psoriasis are unsatisfactory. We applied recently-developed techniques for transcriptomic analys...
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Downregulation of mouse CCR3 by lentiviral shRNA inhibits proliferation and induces apoptosis of mouse eosinophils. Mol Med Rep. 2016 ...
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