The S672R mutation in heart cell ion channels leads to low heart rates and arrhythmia by an unknown route. A multifaceted NMR analysis now demonstrates that this mutant impacts allosteric coupling in domains inside of the cell to change channel activation, providing a mechanistic explanation for phenotypic outcomes.
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In metabolomics, thousands of substances can be detected in a single assay. This capacity motivates the development of metabolomics testing,...
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Cover the initial investigation and management of an unwell infant in our paediatric #surgery module:… https://t.co/305JMiDWX0 from #Alexa...
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