Δευτέρα 6 Μαρτίου 2017

Influence of wall thickness and diameter on arterial shear wave elastography: a phantom and finite element study

Quantitative, non-invasive and local measurements of arterial mechanical properties could be highly beneficial for early diagnosis of cardiovascular disease and follow up of treatment. Arterial shear wave elastography (SWE) and wave velocity dispersion analysis have previously been applied to measure arterial stiffness. Arterial wall thickness ( h ) and inner diameter ( D ) vary with age and pathology and may influence the shear wave propagation. Nevertheless, the effect of arterial geometry in SWE has not yet been systematically investigated. In this study the influence of geometry on the estimated mechanical properties of plates ( h   =  0.5–3 mm) and hollow cylinders ( h   =  1, 2 and 3 mm, D   =  6 mm) was assessed by experiments in phantoms and by finite element method simulations. In addition, simulations in hollow cylinders with wall thickness difficult to achieve in phantoms were performed ( h   =  0.5–1.3 mm, D   =  5–8 mm). The phas...

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