Pulse wave imaging using coherent compounding in a phantom and in vivo

Pulse wave velocity (PWV) is a surrogate marker of arterial stiffness linked to cardiovascular morbidity. Pulse wave imaging (PWI) is a technique developed by our group for imaging the pulse wave propagation in vivo . PWI requires high temporal and spatial resolution, which conventional ultrasonic imaging is unable to simultaneously provide. Coherent compounding is known to address this tradeoff and provides full aperture images at high frame rates. This study aims to implement PWI using coherent compounding within a GPU-accelerated framework. The results of the implemented method were validated using a silicone phantom against static mechanical testing. Reproducibility of the measured PWVs was assessed in the right common carotid of six healthy subjects ( n   =  6) approximately 10–15 mm before the bifurcation during two cardiac cycles over the course of 1–3 d. Good agreement of the measured PWVs (3.97  ±  1.21 m s −1 , 4.08  ±  1.15 m s −1 , p

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