Novel Pre-therapeutic Scoring System Using Patient and Hematological Data to Predict Facial Palsy Prognosis.

Novel Pre-therapeutic Scoring System Using Patient and Hematological Data to Predict Facial Palsy Prognosis.

Clin Otolaryngol. 2017 Feb 21;:

Authors: Wasano K, Ishikawa T, Kawasaki T, Yamamoto S, Tomisato S, Shinden S, Minami S, Wakabayashi T, Ogawa K

Abstract
OBJECTIVES: We describe a novel scoring system, the facial Palsy Prognosis Prediction score (PPP score), which we test for reliability in predicting pre-therapeutic prognosis of facial palsy. We aimed to use readily available patient data that all clinicians have access to before starting treatment.
DESIGN: Multicenter case series with chart review.
SETTING: Three tertiary care hospitals.
PARTICIPANTS: We obtained hematological and demographic data from 468 facial palsy patients who were treated between 2010 and 2014 in three tertiary care hospitals. Patients were categorized as having Bell's palsy or Ramsey Hunt's palsy.
MAIN OUTCOME MEASURES: We compared the data of recovered and unrecovered patients. PPP scores consisted of combinatorial threshold values of continuous patient data (e.g., platelet count) and categorical variables (e.g., gender) that best predicted recovery. We created separate PPP scores for Bell's palsy patients (PPP-B) and for Ramsey Hunt's palsy patients (PPP-H).
RESULTS: The PPP-B score included age (≥65 years), gender (male), and neutrophil-to-lymphocyte ratio (≥2.9). The PPP-H score included age (≥50 years), monocyte rate (≥6.0%), mean corpuscular volume (≥95 fl), and platelet count (≤200,000/μl). Patient recovery rate significantly decreased with increasing PPP scores (both PPP-B and PPP-H) in a step-wise manner. PPP scores (i.e., PPP-B score and PPP-H score) ≥2 were associated with worse than average prognosis.
CONCLUSIONS: PPP scores are useful for predicting prognosis of facial palsy before beginning treatment. This article is protected by copyright. All rights reserved.

PMID: 28222241 [PubMed - as supplied by publisher]

from #AlexandrosSfakianakis via Alexandros G.Sfakianakis on Inoreader http://ift.tt/2luzY8i
via IFTTT