The challenges associated with developing accurate models for cyber-physical systems are attributable to the intrinsic concurrent and heterogeneous computations of these systems. Even though reasoning based on interconnected domain specific ontologies shows promise in enhancing modularity and joint functionality modelling, it has become necessary to build interoperable cyber-physical systems due to the growing pervasiveness of these systems. In this paper, we propose a semantically oriented distributed reasoning architecture for cyber-physical systems. This model accomplishes reasoning through a combination of heterogeneous models of computation. Using the flexibility of semantic agents as a formal representation for heterogeneous computational platforms, we define autonomous and intelligent agent-based reasoning procedure for distributed cyber-physical systems. Sensor networks underpin the semantic capabilities of this architecture, and semantic reasoning based on Markov logic networks is adopted to address uncertainty in modelling. To illustrate feasibility of this approach, we present a Markov logic based semantic event model for cyber-physical systems and discuss a case study of event handling and processing in a smart home.
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