Abstract
Background
The number of patients diagnosed with malignant melanoma (MM) has increased over several years. Despite early diagnosis of MM and therefore better prognosis, the number of FDG-PET/CT scans (PET/CT) seems to be increasing. This study aimed to describe all MM patients who were PET/CT scanned in 2012 at a department of plastic surgery and to analyze the pattern of referral and outcome of PET/CT scans of these patients all back from early diagnosis of the patient in the period 2008–2012.
Methods
All patients with MM stages 1–4 (AJCC stages) and melanoma of unknown primary (MUP) who were PET/CT scanned in 2012 were included. This resulted in a study group of 58 patients with 109 PET/CT scans during the study period 2008–2012.
Results
Indications for referring stages 1 and 2 patients to PET/CT were usually based on subjective symptoms of disease, whilst patients in stages 3 and 4 were usually appointed to a PET/CT based on objective, radiological or histological signs of relapse. Approximately, two thirds of the PET/CT scans of stages 1 and 2 patients, respectively, were negative, which is twice as many compared to stages 3–4. Five patients were upgraded in stage because of a biopsy taken after PET/CT. The number of additional examinations triggered per PET/CT increased with the stages.
Conclusions
Some PET/CT scans of stages 1 and 2, MM patients might have been unnecessary considering the vague indications for referral and the relatively large number of negative scans. Earlier, there was no national guideline for the use of PET/CT scans of MM patients. Hopefully, the recently published guideline from The Danish Health Board will help optimize the cost-benefit of each PET/CT scan.
Level of Evidence: Level IV, diagnostic study.
from #AlexandrosSfakianakis via Alexandros G.Sfakianakis on Inoreader http://ift.tt/2bL5RJi
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