Enhancing the Utility of Antibiotic Susceptibility Reporting as a Tool for Antimicrobial Stewardship

Opinion Statement

Hospital antibiograms are a method for presenting cumulative antibiotic susceptibility data using routinely collected clinical microbiology data. They provide critical foundational knowledge to inform development of antimicrobial stewardship program (ASP) strategies but are also provided to clinicians to inform empiric antibiotic therapy selection. Earlier research has demonstrated that use of the antibiogram to direct prudent antibiotic selection is less than desired. Use by non-infectious disease practitioners has been limited, and antibiotic prescribing has not aligned with ASP goals. Over the past 5 years, newer research has emerged to increase the utility of the antibiogram through education, stratification, and cross-tabulation of data for combination therapy. These approaches focus on increasing use of the cumulative antibiogram and ensuring that the data appropriately influence the antibiotic therapy selection. Data available to date suggest that these strategies can be effective methods of increasing use of concordant and relatively narrow spectrum empiric antibiotic regimens.

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