Gorantla Shravya Keerthi, Pravati Pal, Gopal Krushna Pal, Jaya Prakash Sahoo, Magadi Gopalakrishna Sridhar, Jayaraman Balachander
International Journal of Clinical and Experimental Physiology 2016 3(3):127-133
Background and Aim: Although diabetes is known to be associated with cardiac autonomic neuropathy and depressed quality of life (QoL) in terms of physical and psychological domains due to the disease duration and complications, till date no reports are available to show the link between QoL and Indian Diabetes Risk Score (IDRS) with cardiac autonomic neuropathy assessed with heart rate variability (HRV) in newly diagnosed type 2 diabetes mellitus and prediabetes without comorbidities. IDRS is known to predict cardiometabolic risks, neuropathy and future diabetes risk even in normoglycemic subjects. Hence, in this study, we have planned to assess the plausible link between QoL scale and IDRS with HRV in young Indian individuals with newly diagnosed diabetes and prediabetes. Methods: Among 328 (18–45 years) age-matched individuals, 78 were included as controls, 126 in prediabetes group, and 124 in newly diagnosed diabetes group. Subject's QoL and IDRS were assessed by questionnaires, and resting HRV were recorded. Fasting blood glucose (FBG) and fasting insulin was estimated, and homeostatic model assessment of insulin resistance (HOMA-IR) was calculated. Independent association of ratio of low-frequency to high-frequency power (LF: HF ratio) with other variables was analyzed by multiple regression analysis. Results: HRV and QoL were significantly decreased; IDRS, FBG, fasting insulin, and HOMA-IR were significantly increased in prediabetes and diabetes group compared to controls with an equal level of significance. Furthermore, these parameters showed significant difference that was more intense in diabetes group compared with prediabetes group. Conclusion: The association of sympathovagal imbalance in terms of LF: HF ratio with QoL and IDRS was found in Indian adults with prediabetes and diabetes even in the younger age without having any disease complications.
from #AlexandrosSfakianakis via Alexandros G.Sfakianakis on Inoreader http://ift.tt/2cWB0cr
via IFTTT
Εγγραφή σε:
Σχόλια ανάρτησης (Atom)
Δημοφιλείς αναρτήσεις
-
Publication date: Available online 4 January 2018 Source: European Journal of Radiology Author(s): Peiyao Zhang, Jing Wang, Qin Xu, Zhen...
-
Publication date: March 2017 Source: Free Radical Biology and Medicine, Volume 104 from #AlexandrosSfakianakis via Alexandros G.Sfak...
-
Dtsch med Wochenschr DOI: 10.1055/s-0043-100054 Hintergrund und Fragestellung Ein etablierter Weg, die optimale Behandlung von Tumorpatien...
-
Background Hyperthyroidism is associated with increased thrombotic risk. As contact system activation through formation of neutrophil extrac...
-
Deepak Thapa, Vanita Ahuja, Deepanshu Dhiman Indian Journal of Anaesthesia 2017 61(12):1012-1014 from #AlexandrosSfakianakis via Alexa...
-
BACKGROUND AND PURPOSE: Dengue is a common arboviral disease, which uncommonly involves the brain. There has been a recent surge in dengu...
-
Abstract Limited memory size is considered as a major bottleneck in data centers for intelligent urban computing. It is shown that there e...
-
Linked Article: Maintz et al. Br J Dermatol 2017; 176:481–487 . from #AlexandrosSfakianakis via Alexandros G.Sfakianakis on Inoreader h...
-
Publication date: Available online 28 February 2018 Source: Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology Author(s): Mo...
Δεν υπάρχουν σχόλια:
Δημοσίευση σχολίου