The evolving role of nivolumab in non-small-cell lung cancer for second-line treatment: a new cornerstone for our treatment algorithms. Results from an International Experts Panel Meeting of the Italian Association of Thoracic Oncology

Lung cancer is the leading cause of death from cancer worldwide that current has only a few available treatment options in patients with no driver mutations. The therapeutic options for patients with non-small-cell lung cancer (NSCLC) who progress after first-line chemotherapy have been limited from a long time. Docetaxel has remained a cornerstone of second-line treatment for more than 20 years, but it is associated with an unfavourable safety profile. Recently, the results from immunotherapy treatment with anti-PD1 and PD-L1 inhibitors has changed our current knowledge base and increased therapeutic options for patients with NSCLC in the second-line setting.

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