2016-10-16T02-20-53Z
Source: Indo American Journal of Pharmaceutical Research
Mr. Hemant D. Patil, Mr. Sachin S. Rane, Prof. (Dr.) Rajesh Y. Chaudhari, Prof. (Dr.) Vijay R. Patil.
Nifedipine, the prototype of the dihydropyridine class of calcium channel antagonists which used to treat Prinzmetal's angina, hypertension and other vascular disorders by blocking the calcium channels. In such cases, mouth dissolving dosage forms will be an effective solution for patient compliance and efficient medicine regimen. In the present research, mouth dissolving tablet of Nifedipine was made using various tabletiing aids. The prepared tablets were evaluated for weight, thickness, hardness, friability with disintegration time of less than 30 seconds and drug dissolution of about 75% achieved within 30 minutes. The prepared tablets were stability tested at 40°C having 75% Relative Humidity for 3 months and were found to be stable. Prepared mouth dissolving tablets of Nifedipine 10 mg was found to be bioequivalent under fasting and fed conditions.
http://ift.tt/2e83iQR
Κυριακή 16 Οκτωβρίου 2016
FORMULATION AND EVALUATION OF NIFIDEPINE MOUTH DISSOLVING TABLET BY SUBLIMATION TECHNIQUE
Εγγραφή σε:
Σχόλια ανάρτησης (Atom)
Δημοφιλείς αναρτήσεις
-
Publication date: Available online 4 January 2018 Source: European Journal of Radiology Author(s): Peiyao Zhang, Jing Wang, Qin Xu, Zhen...
-
BACKGROUND AND PURPOSE: Lesion load is a common biomarker in multiple sclerosis, yet it has historically shown modest association with cl...
-
Does CBD Oil Lower Blood Pressure? This article was originally published at SundayScaries." Madeline Taylor POSTED ON January 13, 20...
-
Despite widespread journal endorsement of reporting guidelines, the poor reproducibility of preclinical research is increasingly under debat...
-
The benefit of the breastfeeding has been well-established. In comparison to partial breast feeding, exclusive breastfeeding has even more b...
-
A report of the Cold Spring Harbor Laboratory/Wellcome Trust Meeting on Engineering Principles in Biology, Cambridge, UK, 14-16 October 2009...
-
Abstract We report here a microscopic tight-binding theoretical study of the dynamic dielectric response of graphene-on-polarizable substr...
-
Volumetry measurement of lung nodules is gaining clinical acceptance but still... Read more on AuntMinnieEurope.com Related Reading: Ul...
-
Background Hyperthyroidism is associated with increased thrombotic risk. As contact system activation through formation of neutrophil extrac...
Δεν υπάρχουν σχόλια:
Δημοσίευση σχολίου