Medicine by Alexandros G. SfakianakisThe relationship of hypertension with obesity and obstructive sleep apnea in adolescents.: The relationship of hypertension with obesity and obstructive sleep apnea in adolescents.Pediatr Pulmonol. 2020 Feb 18;:Authors: Khan MA, Mathur K, Barraza G, Sin S, Yang CJ, Arens R, Sutton N, Mahgerefteh JAbstract OBJECTIVES: To assess the independent relationships of obesity and obstructive sleep apnea (OBA) with hypertension/elevated blood pressure (EBP) in adolescent patients. STUDY DESIGN:...
Combination of head-up sleep and vertical recognition training may cure intractable motion-evoked dizziness with unknown origin.: Combination of head-up sleep and vertical recognition training may cure intractable motion-evoked dizziness with unknown origin.Acta Otolaryngol. 2020 Feb 18;:1-6Authors: Kitahara T, Horinaka A, Shiozaki T, Ito T, Wada Y, Yamanaka T, Nario KAbstract Background: It has been reported that head-up sleep (HUS) prevents free-floating otoliths from entering canals and...
Audiological outcome measures with the BONEBRIDGE transcutaneous bone conduction hearing implant: impact of noise, reverberation and signal processing features.: Audiological outcome measures with the BONEBRIDGE transcutaneous bone conduction hearing implant: impact of noise, reverberation and signal processing features.Int J Audiol. 2020 Feb 18;:1-10Authors: Curca IA, Parsa V, Macpherson EA, Scollie S, Vansevenant K, Zimmerman K, Lewis-Teeter J, Allen P, Parnes L, Agrawal SAbstract Objective:...
Assessing Free Flap Reconstruction Accuracy of the Midface and Orbit Using Computer-Aided Modeling Software.: Assessing Free Flap Reconstruction Accuracy of the Midface and Orbit Using Computer-Aided Modeling Software.Facial Plast Surg Aesthet Med. 2020 Feb 18;:Authors: Zhu B, Han M, Heaton C, Park AM, Seth R, Knott PDAbstract Importance: Aesthetically pleasing and functionally stable total maxillectomy reconstruction is among the greatest of challenges within head and neck surgery. Maintaining...
Implications of Tumor Size, Subsite, and Adjuvant Therapy on Outcomes in pT4aN0 Oral Cavity Carcinoma.: Implications of Tumor Size, Subsite, and Adjuvant Therapy on Outcomes in pT4aN0 Oral Cavity Carcinoma.Otolaryngol Head Neck Surg. 2020 Feb 18;:194599820904679Authors: Namin AW, Bollig CA, Harding BC, Dooley LMAbstract OBJECTIVE: To determine if tumor size, subsite, and adjuvant radiation therapy (AXRT) are associated with overall survival (OS) in patients with pT4aN0 oral cavity squamous...
Risk Factors and Outcomes of Postoperative Recurrent Well-Differentiated Thyroid Cancer: A Single Institution's 15-Year Experience.: Risk Factors and Outcomes of Postoperative Recurrent Well-Differentiated Thyroid Cancer: A Single Institution's 15-Year Experience.Otolaryngol Head Neck Surg. 2020 Feb 18;:194599820904923Authors: Amin SN, Shinn JR, Naguib MM, Netterville JL, Rohde SLAbstract OBJECTIVE: Identify risk factors and outcomes of recurrent well-differentiated thyroid cancer. ...
Novel EGFR ectodomain mutations associated with ligand-independent activation and cetuximab resistance in head and neck cancer.: Novel EGFR ectodomain mutations associated with ligand-independent activation and cetuximab resistance in head and neck cancer.PLoS One. 2020;15(2):e0229077Authors: Nair S, Trummell HQ, Rajbhandari R, Thudi NK, Nozell SE, Warram JM, Willey CD, Yang ES, Placzek WJ, Bonner JA, Bredel MAbstract Epidermal growth factor receptor (EGFR) is a pro-tumorigenic receptor tyrosine...
The Efficacy of Oral Celecoxib Following Surgical Rhinoplasty.: The Efficacy of Oral Celecoxib Following Surgical Rhinoplasty.Facial Plast Surg Aesthet Med. 2020 Feb 18;:Authors: Newberry CI, McCrary HC, Cerrati EWAbstract Importance: Exploring potential methods of controlling postoperative rhinoplasty pain with non-narcotic medications. Objective: To examine the effects of celecoxib in reducing pain and possible opioid consumption after rhinoplasty surgery. Design, Setting, and Participants:...
Enhanced Efficacy of Dust Mite Sublingual Immunotherapy in Low-Response Allergic Rhinitis Patients after Dose Increment at 6 Months: A Prospective Study.: Enhanced Efficacy of Dust Mite Sublingual Immunotherapy in Low-Response Allergic Rhinitis Patients after Dose Increment at 6 Months: A Prospective Study.Int Arch Allergy Immunol. 2020 Feb 18;:1-9Authors: Gao Y, Lin X, Ma J, Wei X, Wang Q, Wang MAbstract BACKGROUND: Several studies have suggested that sublingual immunotherapy (SLIT) involves...
Elucidation of the effect of plumbagin on the metastatic potential of B16F10 murine melanoma cells via MAPK signalling pathway: AbstractMelanoma is the most dangerous form of skin cancer with a very poor prognosis. Melanoma develops when unrepaired DNA damage causes to skin cells to multiply and form malignant tumors. The current therapy is limited by the highly ability of this disease to metastasize rapidly. Plumbagin is a naphthoquinone (5‐hydroxy‐2‐methyl‐1, 4‐naphthoquinone), isolated from the...
Keratinocyte aquaporin‐3 expression induced by histone deacetylase inhibitors is mediated in part by peroxisome proliferator‐activated receptors (PPARs): AbstractThe water and glycerol channel, aquaporin‐3 (AQP3), plays an important role in the skin epidermis, with effects on hydration, permeability barrier repair and wound healing; therefore, information about the mechanisms regulating its expression is important for a complete understanding of skin function physiologically and in disease conditions....
Heliovaccination: Solar mediated immunity against cancer: AbstractThe protective effect of ultraviolet (UV) light against a host of malignancies is well characterised. It was recognised by WHO in their 2006 publication on the global burden of UV‐mediated disease. The mechanism by which this oncoprotective effect occurs remains unclear. Vitamin D has been mooted as a potential mediator. However, the evidence does not support this. I suggest that UV irradiation of the skin produces nascent malignant...
Different results of tracheoplasty for various tracheal diseases: Ming-Ho WuFormosan Journal of Surgery 2020 53(1):14-19Background: Tracheoplasty is a challenging surgical procedure for treating tracheal diseases. Preserving the voice and achieving normal breaths are considered favorable results. This article reports the mid-term results of tracheoplasty.Materials and Methods: From July 1988 to June 2018, a total of 91 adults with various tracheal diseases who underwent tracheoplasty were enrolled...
The impact of alcohol intoxication on injury severity and outcomes of adult patients with different trauma type: Yee-San Lee, Chih-Fang Huang, Pei-Ming Wang, Shu-Hui Peng, Hang-Tsung Liu, Ching-Hua HsiehFormosan Journal of Surgery 2020 53(1):8-13Background: This study was designed to investigate the impact of alcohol intoxication on injury severity and outcomes of adult patients who experienced different modes of trauma.Materials and Methods: This retrospective study collected data of hospitalized...
Dilemma in primary hyperparathyroidism with multiple brown tumors: Girish Mysore Suresh, Ravi Arjunan, S Altaf, Veerendra KumarFormosan Journal of Surgery 2020 53(1):35-38Primary hyperparathyroidism (PHPT) is a disease characterized by excessive secretion of parathormone. During the disease, bone loss occurs, particularly depending on the resorption of the skeletal system. One of the complications of PHPT is fibrotic, cystic bony changes which are called a brown tumor (BT). Skeletal manifestations...
Accessory tragus: Report of a case in a rare location on the nasal vestibule: AbstractA case of an accessory tragus located on the nasal vestibule is reported. This represents the third case of this entity located outside of a derivative of a branchial arch. All three of these cases were located in the nose/glabella region.
Good response to pulsed dye laser in patients with capillary malformation‐arteriovenous malformation syndrome (CM‐AVM): AbstractCapillary malformation‐arteriovenous malformation syndrome (CM‐AVM) is an autosomal dominant disorder caused by heterozygous mutations in RASA1 and EPHB4. Capillary stains in CM‐AVM are compatible with Schöbinger's phase I AVMs. Vascular laser has been classically contraindicated for the treatment of AVMs, as there is a fear of accelerating their progression. In this study,...
Basosquamous carcinoma and melanoma collision tumor in a child with xeroderma pigmentosum: AbstractXeroderma pigmentosum (XP) is a rare autosomal recessive genodermatosis associated with hypersensitivity to ultraviolet radiation (UVR), being due to defects involving the nucleotide excision repair pathway. Patients with XP are prone to develop multiple cutaneous neoplasms including non‐melanoma skin cancers and melanoma. Collision tumors in patients with XP have been reported in the literature including...
Treatment of superficial vascular anomalies with topical sirolimus: A multicenter case series: AbstractBackgroundSystemic sirolimus (rapamycin) has recently been found effective in treating complex vascular anomalies by reducing the size and associated complications. Many vascular anomalies have a cutaneous component, and thus, we sought to determine whether topical administration of sirolimus may be an effective therapy, as data on the use of topical sirolimus are limited.ObjectiveWe reviewed the...
Hoarse cry in a newborn with epidermolysis bullosa simplex, generalized severe: AbstractHoarse cry and respiratory stridor are the signs of potentially life‐threatening laryngeal involvement in selected severe and frequently early lethal subtypes of inherited epidermolysis bullosa (EB). We present a newborn with generalized skin blistering and onychodystrophy who developed a hoarse cry and inspiratory stridor. Ultrastructural skin examination revealed tonofilament clumping in basal keratinocytes...
Oral erosions associated with surreptitious marijuana vaping in an adolescent boy: AbstractA 15‐year‐old boy presented with painful ulcerations affecting the oral mucosa that were eventually attributed to marijuana vaping. In this case report, we highlight cannabis vaping as a potential cause of oral erosions due to injury and chronic inflammation of the oral mucosa.
Allergic contact dermatitis caused by wound closure tape in a pediatric patient: AbstractWound care products are emerging as causes of allergic contact dermatitis (ACD). There are increasing reports of ACD to certain medical adhesives; however, there are no published reports of contact sensitization solely due to wound closure tape such as Steri‐Strips™. Herein, we present the first confirmed case of ACD in a child caused by wound closure tape.
Stüve‐Wiedemann syndrome with multiple eruptive vellus hair cysts and clefted tongue: AbstractStüve‐Wiedemann syndrome is a rare autosomal recessive congenital primary skeletal dysplasia, characterized by small stature, bowed long bones, joint restrictions, hyperthermic episodes, dysautonomia, and respiratory and feeding difficulties, that usually leads to early mortality. Cutaneous manifestations have rarely been reported. We report the case of a girl with Stüve‐Wiedemann syndrome presenting with...
Characterizing calcinosis cutis in a pediatric population: AbstractBackground/ObjectivesCalcinosis cutis is the abnormal deposition of calcium in the skin and subcutis. There is currently a paucity of data surrounding pediatric calcinosis cutis. The objective of this study is to characterize calcinosis cutis in a pediatric cohort.MethodsA single‐institution retrospective cohort study was performed over a 5.5‐year period.ResultsThirty cases were identified. Calcinosis cutis was found to be more common...
Dermoscopic findings of a congenital smooth muscle hamartoma in an infant: AbstractCutaneous smooth muscle hamartoma is an uncommon, benign tumor developing in the dermis as a result of disorganized hyperproliferation of arrector pili muscle fibers. We present a 1‐month‐old infant with a congenital smooth muscle hamartoma together with the dermoscopic findings of the case. Dermoscopy can be a helpful non‐invasive tool in diagnosing congenital smooth muscle hamartoma due to its distinct findings that...
Microphthalmia and linear skin defects syndrome: Precise diagnosis guides prognosis: AbstractMicrophthalmia and linear skin defects syndrome (MLS) is a rare X‐linked dominant disorder characterized by microphthalmia and linear atrophic plaques of the face and neck. The diagnosis of MLS can be challenging secondary to both its rarity and to clinical overlap with Goltz syndrome. Whereas the skin lesions of MLS are more likely to improve in appearance with age, the lesions of Goltz are typically persistent.
A PIK3CA mutation in an acquired capillary malformation: AbstractAcquired capillary malformations are rare vascular anomalies composed of dilated capillaries in the skin. We present a pediatric case of an acquired capillary malformation as a novel presentation of the PIK3CA‐related overgrowth syndromes. Using next‐generation sequencing, we identified a PIK3CA p.Val344Met mutation within the acquired capillary malformation with possible prognostic and therapeutic significance.
The association between atopic dermatitis and serum 25‐hydroxyvitamin D in children: Influence of sun exposure, diet, and atopy features—A cross‐sectional study: AbstractBackgroundPrevious studies have linked low serum vitamin D (VD) or 25‐hydroxyvitamin D (25(OH)D) levels with increased severity of atopic dermatitis (AD) in children.ObjectiveTo investigate the association between serum VD (25(OH)D) levels and AD and AD severity, considering the influence of diet and sun exposure.MethodsWe performed...
Pemphigus‐like eruption as a complication of molluscum contagiosum treatment with imiquimod in a 5‐year‐old girl: AbstractPemphigus and pemphigus‐like reactions can be triggered by a variety of medications including topical therapies, such as imiquimod. While the association between imiquimod and pemphigus‐like reactions has been reported in adults, this is the first report of a generalized reaction beyond the site of imiquimod application in a child. The mechanism by which this occurs may be through...
Skin and nails abnormalities in a patient with ZTTK syndrome and a de novo mutation in SON: AbstractZhu‐Tokita‐Takenouchi‐Kim (ZTTK) syndrome is a rare, severe, and recently described multisystem developmental disorder characterized by delayed psychomotor development and intellectual disability, characteristic facial features, hypotonia, poor overall growth, and visual abnormalities. Mucocutaneous manifestations have not been reported so far among individuals with ZTTK syndrome. Herein, we present...
Low risk of clinically important central nervous system dysraphism in a cohort study of 69 patients with isolated aplasia cutis congenita of the head: AbstractBackgroundAplasia cutis congenita of the head may be associated with underlying fusion defects in the skin, soft tissues, muscle, or bone. The risk of central nervous system dysraphism in patients with aplasia cutis congenita is not known; however, knowledge of underlying structural defects can inform management considerations.MethodsThis retrospective...
Retrospective review of drug‐induced Stevens‐Johnson syndrome and toxic epidermal necrolysis cases at a pediatric tertiary care institution: AbstractBackground/ObjectivesStevens‐Johnson syndrome and toxic epidermal necrolysis represent important sources of potential mortality and morbidity in children. There is a need for more clinical data in this population to determine whether specific treatments preferentially improve outcomes.MethodsThis was a single‐center retrospective review of children admitted...
A pediatric approach to management of skin growths in basal cell nevus syndrome: AbstractLittle guidance on management of basal cell nevus syndrome in children exists. We report a case series of four patients diagnosed with BCNS in early childhood, in whom several highly suspicious lesions were biopsied, but several smaller and questionably concerning lesions were treated with therapies that are more tolerable for children, including topical imiquimod, 5‐fluorouracil, cryotherapy, or touch electrodessication...
Comprehensive prosthetic rehabilitation of a case of the orofacial digital syndrome: Rajat Lanzara, M Viswambaran, Anup GopiThe Journal of Indian Prosthodontic Society 2020 20(1):110-114Maxillofacial defects can result from trauma, treatment of neoplasm, or congenital malformations. Many a time due to the size, location of the defect, or because of the patient's medical condition, surgical reconstruction may not be possible. In these cases, rehabilitation is indicated with the help of a maxillofacial...
Classification of anatomical variants of maxillary sinus shapes and symmetry using computerized tomographic imaging: Abdulhameed Aliu, Ma'aji S Mohammad, Bello S Sirajo, Ahmad M Ibrahim, Zagga D AbdullahiSub-Saharan African Journal of Medicine 2019 6(3):143-147Background: The maxillary sinus is characterized by a considerable variation in sizes and shapes and between the right and left sides. Due to easy access to all its walls and surfaces, imaging via computerized tomography (CT) has enhanced the...
Comparison of the Aditus ad Antrum Diameter on CT between Patients with Chronic Otitis Media and Healthy Individuals.: Related ArticlesComparison of the Aditus ad Antrum Diameter on CT between Patients with Chronic Otitis Media and Healthy Individuals.Curr Med Imaging Rev. 2019;15(10):990-993Authors: Gündoğdu E, Toprak UAbstract BACKGROUND: The middle ear cavity is ventilated through the aditus ad antrum. Aditus blockage contributes to the pathology of otitis media. OBJECTIVE: To determine...
Environmental radioactivity levels in agricultural soil and wheat grains collected from wheat-farming lands of Koya district, Kurdistan region-Iraq: Najeba Farhad Salih, Zakariya Adel Hussein, Shalaw Zrar SedeeqRadiation Protection and Environment 2019 42(4):128-137The purpose of this study is to determine the activity concentration levels of radionuclides of226Ra,232Th,40K, and137Cs in soil and wheat grain samples. A total of 72 samples of soil and wheat grains were collected in the study area....
Evaluation of the radiation dose from radon ingestion from different types of drinking water samples
Evaluation of the radiation dose from radon ingestion from different types of drinking water samples in Egypt using nuclear track detectors (LR-115 Type II): Ahmed Saad HusseinRadiation Protection and Environment 2019 42(4):168-172Radon concentrations in different sources of water samples collected from five different regions of Egypt by alpha track dosimetry using LR-115 detectors were determined. The values of radon concentration in water samples did not exceed the maximum level of contamination...
Dilated cardiomyopathy following H1N1 infection: Sweta Shanbhag, Rashmi Alva, K Shreedhara AvabrathaMuller Journal of Medical Sciences and Research 2019 10(2):86-88Acute myocarditis and dilated cardiomyopathy are known to be common manifestations of several viral infections, presenting with a wide spectrum of symptoms. The exact pathogenesis of influenza virus-induced myocarditis is still unclear. Management involves early detection using echocardiography and cardiac support to tide over acute phase....
Hypohidrotic ectodermal dysplasia with autosomal inheritance: A rare entity: Ayushi Lodha, Shylaja SomeshwarMuller Journal of Medical Sciences and Research 2019 10(2):82-85Hypohidrotic ectodermal dysplasia (HED) is a rare disorder which is characterized by the involvement of all ectodermal derivatives and marked deficiency of sweating. It has a prevalence of 1: 100,000. X-linked recessive fashion is the most common pattern of inheritance, and 90% of the individuals affected are males. Autosomal dominant...
Exploring the anti-allergic property of potentized sodium chloride using nasal eosinophil count as a criterion: Dania P Johnson, K John PaulMuller Journal of Medical Sciences and Research 2019 10(2):47-50Background: Nasal eosinophilia is a specific and valuable means for diagnosing and predicting the prognosis of allergic rhinitis (AR). Evidence-based recommendation for treating AR with homeopathic medicines is lacking. Symptomatology of Natrum Muriaticum (NM) derived from homeopathic pathogenetic...
Pulmonary actinomycosis presenting as a pleural tumour: Neeraj Kumar Keyal, Raju Shrestha, Niru Nepal, Manish NakarmiThe Journal of Association of Chest Physicians 2020 8(1):23-25Pulmonary actinomycosis is a rare gram positive higher prokaryotic bacterial infection. We hereby present a case of 78-year old male presented with non-specific symptoms like cough, shortness of breath (SOB) and chest pain mimicking as pulmonary tuberculosis, fungal infection and lung cancer but was diagnosed to have pulmonary...
A rare case of granulomatosis with polyangiitis (Wegener's) presenting with tracheo-bronchial involvement: Pragyan Rout, Bijay Meher, Garima Markam, Kiran SabatThe Journal of Association of Chest Physicians 2020 8(1):30-32Granulomatosis with polyangiitis (Wegener's) (GPA) is a form of systemic vasculitis that involves primarily the upper and lower airways and the kidneys. Although the pulmonary involvement of GPA is well described, the lower airway findings are rarely involved, and only various descriptions...
Erasmus Syndrome: Co-existence of silicosis and progressive systemic sclerosis in a 55 year old male
Erasmus Syndrome: Co-existence of silicosis and progressive systemic sclerosis in a 55 year old male: Jitendra Jalutharia, Ramakant DixitThe Journal of Association of Chest Physicians 2020 8(1):19-22The Erasmus syndrome describes the association of generalised progressive scleroderma following exposure to silica with or without silicosis. We report a case of Erasmus Syndrome in a 55-year old labourer presenting with shortness of breath, arthralgia, Raynaud's phenomenon, skin tightening and microstomia...
Impact of obstructive sleep apnea and sleep parameters on level of asthma control: Ramakant Dixit, Satyadeep Verma, Mukesh GoyalThe Journal of Association of Chest Physicians 2020 8(1):1-5Background and Objective: Several studies support high prevalence of obstructive sleep apnea (OSA) symptoms in patients with asthma. Our objective was to evaluate the relationship between OSA severity and level of asthma control if any and analyze sleep parameters in patients having different levels of asthma control....
Disseminated Multidrug-Resistant Tuberculosis in a Young Patient: A Rare Case Report: Ritu Dadra, Nirmal Chand Kajal, Balbir Malhotra, Prasanth Pandiyaraj, Lakhvir Kaur, Gurleen kaurThe Journal of Association of Chest Physicians 2020 8(1):26-29Drug resistance is a persistent threat to tuberculosis (TB) control program worldwide. Patients infected with multiple drug-resistant strains are less likely to become cured. Management of resistant cases is complex and presents therapeutic limitations. Patients...
An unusual case of Salmonella enterica subtype Typhi causing pneumonia, synpneumonic effusion, and septic shock in an immunocompetent pregnant patient: Arun Agarwal, Pooja Parab, Madan Mohan SharmaThe Journal of Association of Chest Physicians 2020 8(1):33-36Salmonellosis may present with varying clinical manifestations ranging from fever, malaise, abdominal discomfort, and gastroenteritis to nonspecific symptoms related to febrile syndromes. Pneumonia, however, is an atypical site for Salmonellosis....
Current status of full-endoscopic spine surgery in cervical spine: Anterior and posterior approach: Sagar B Sharma, Jin-Sung Luke Kim, Naveen D Siddappa, Hussam E JabriIndian Spine Journal 2020 3(1):41-53The techniques for the treatment of cervical disc herniation and cervical myelopathy have evolved over the last two decades. Anterior cervical decompression and fusion has been considered to be the gold standard technique to date. Recently, it has been shown that full-endoscopic spine surgery with...
Traumatic thoracic spine intramedullary hemorrhage: Rare spinal cord injury: Nitesh Gahlot, Abhay ElhenceIndian Spine Journal 2020 3(1):123-126The aim of this study was to report a rare case of post-traumatic thoracic spine intramedullary bleeding associated with spine fracture in the absence of compression due to fracture fragments on spinal cord. Magnetic resonance imaging scan showed thrombus formation inside the spinal cord with obliteration of neural elements. The patient was managed non-operatively...
Single-level lumbar pyogenic discitis treated with combined minimally invasive posterior and mini-open anterior approach: Functional outcome analysis: Charanjit Singh Dhillon, Narendra R Medagam, Shrikant Ega, Raviraj Tantry, Nilay P ChhasatiaIndian Spine Journal 2020 3(1):102-109Study Design: This was a retrospective study. Objective: The objective of this study was to evaluate the clinico-radiological outcome in single-level lumbar pyogenic discitis treated with single-stage combined percutaneous...
Expanding the horizons of minimally invasive spine surgery: Arvind G Kulkarni, Tushar S Kunder, Swaroop Das, Sandeep TapashettiIndian Spine Journal 2020 3(1):11-25The trend of using smaller operative corridors is observed in various surgical specialties. The development of smart technologies with the overall aim of reducing surgical trauma has resulted in the concept of minimally invasive surgical techniques. Enhancements in microsurgery, tubes, endoscopy, and various percutaneous techniques, as...
Grade III Spondylolisthesis L5-S1 Treated by Minimally Invasive Spine Transforaminal Lumbar Interbody Fusion (MIS-TLIF) in a Patient of Rheumatoid Arthritis: Vinay H Patel, Vishal B PeshwattiwarIndian Spine Journal 2020 3(1):91-96We present a case of a 76-year-old woman on treatment for rheumatoid arthritis, who was bedridden for the past 3 months due to severe neurological claudication. The patient's radiologic evaluation showed Grade III spondylolisthesis. Spondylolisthesis was treated with minimally...
Larger screw on the concave side of apex pedicle: Friend or foe? Report on a rare cause of neurological deficit in scoliosis surgery: Bhavuk Garg, Nishank Mehta, Ashok JaryalIndian Spine Journal 2020 3(1):114-117Pedicle screw instrumentation is currently the "gold standard" in scoliosis surgery. However, placement of pedicle screws in thoracic spine is considered challenging. Previous studies have described morphometric changes in the pedicle when a larger screw is inserted, with pedicle expansion...
A case of gingival stem cell administration using adipose tissue-derived stem cells: Yukako SuzukiJournal of Oral Research and Review 2020 12(1):42-46Adipose tissue-derived stem cells (ASCs) are reported to be capable of differentiating into all of mature cells, including bones and cartilage as same as bone marrow mesenchymal stem cells. In this study, we examined to treat periodontal disease using autologous ASCs to avoid rejection by transplantation. After autologous ASCs were injected into the...
Comparison of temporomandibular changes in edentulous and dentulous patients using digital panoramic imaging: Nikhil Rajesh Gharge, SR Ashwinirani, Abhijeet SandeJournal of Oral Research and Review 2020 12(1):17-22Introduction: Prevalence of TMJ disorder in general population is approximately 50% out of which 3-7% are reported to seek treatment. Various modalities are used to diagnosis TMJ like Panoramic Imaging, Computed Tomography, Magnetic Resonance Imaging, Cone Beam Computed Tomography. The...
Bone one session treatment: A new concept of treating periodontal diseases: Jilkapally Sai Priya, Kanakagiri Phani Yasaswini, Jammula Surya PrasannaJournal of Oral Research and Review 2020 12(1):47-51Periodontitis is an inflammatory disease of multifactorial origin that represents the destruction of periodontium due to the upregulation of immune response and in the presence of disease-causing pathogens, resulting in loss of attachment and bone loss. Advances in periodontal disease control cracked...
Comparative clinical evaluation of supplementation with omega-3 fatty acids, given for different time period, in chronic periodontitis patients: Govind Bhartiya, Triveni Kale, Swapna Mahale, Shruti Shankarrao LendheyJournal of Oral Research and Review 2020 12(1):11-16Aim: The aim of the study was to evaluate the effects of supplementation with omega-3 (ω-3) polyunsaturated fatty acids (FAs) as host modulating agent, given at varying interval, in patients with chronic periodontitis.Materials and Methods:...
Peripheral ossifying fibroma of the anterior maxilla: A case report and brief review: Aishwarya Madhukar Kale, Kunal Sundar Sethi, Prerna Ashok KardeJournal of Oral Research and Review 2020 12(1):38-41Peripheral ossifying fibroma (POF) presents as a tumor-like growth of the soft tissue and is often associated with sharp teeth, rough restoration, and ill-fitting denture. POF is fibro-osseous in origin and is commonly found in the maxillary region. It is a slow-growing benign tumor and usually asymptomatic....
Accuracy and Reliability of Smartphone Self-Test Audiometry in Community Clinics in Low Income Settings: A Comparative Study: Annals of Otology, Rhinology &Laryngology, Ahead of Print. Background:There is a lack of hearing health care globally, and tele-audiology and mobile technologies have been proposed as important strategies to reduce the shortfall.Objectives:To investigate the accuracy and reliability of smartphone self-test audiometry in adults, in community clinics in low-income settings.Methods:A...
Thyroglossal Duct Cyst Occupying Posterior Hyoid Space with Endolaryngeal Extension Presenting After Neck Trauma: Annals of Otology, Rhinology &Laryngology, Ahead of Print. Objective:Thyroglossal duct cysts are the most common congenital neck mass. They typically present as a painless midline neck mass in a child or young adult, but may also present later in adulthood when the cyst becomes symptomatic. Thyroglossal duct cysts are most commonly located inferior to the hyoid bone in close relation...
Chemical, Electrical and Tactile Sensitivity Changes After Middle Ear Surgery: Annals of Otology, Rhinology &Laryngology, Ahead of Print. Objective/Hypothesis:Taste disturbances are often seen in patients after middle ear surgery due to the stress received by an unprotected chorda tympani. It has also been reported that loss in tactile sensitivity may accompany this issue. The current study was designed to measure electrical, chemical, and tactile sensitives of several senses involved in oral...
Nasal Septal Abscess Caused by Protrusion of a Dental Implant Into the Nasopalatine Duct: A Case Report: Annals of Otology, Rhinology &Laryngology, Ahead of Print. Objective:A nasal septal abscess after placement of a dental implant is seldom seen and is usually caused by an infection around the implant. A septal haematoma following dental implantation leading to septal abscess formation has never been reported.Methods and results:We present a case of a patient who developed a septal abscess...
Multi-Institutional Regional Otolaryngology Bootcamp: Annals of Otology, Rhinology &Laryngology, Ahead of Print. Introduction:In order to increase junior resident physician proficiency and improve patient safety, simulation-based procedural training courses, or bootcamps, have been become an emerging educational tool.Objectives:To compare pre- and post-course confidence levels and to assess station efficacy after completion of our single day bootcamp.Methods:We developed the University of California...
Aging Effects on Esophageal Transit Time in the Upright Position During Videofluoroscopy: Annals of Otology, Rhinology &Laryngology, Ahead of Print. Objectives:The purpose of this study was to examine age-related effects on esophageal transit times (ETT) among healthy adult participants.Methods:A total of 175 healthy, non-dysphagic participants underwent a modified barium swallow study (MBSS), and ETT was recorded for two standardized swallowing tasks. Differences across age groups were determined...
Adult Aortotracheal Fistula as Sequela of Double Aortic Arch Repair in Infancy: A Case Report: Annals of Otology, Rhinology &Laryngology, Ahead of Print. Introduction:Double aortic arch is a rare congenital malformation of the aortic arch that most frequently presents in childhood. Early surgical intervention typically yields excellent outcomes.Objectives:To describe aortotracheal fistula as a rare, yet serious complication of vascular ring and subsequent aortic aneurysm in an adult patient.Methods:Clinical...
Cochlear Implants in Alström Syndrome: Annals of Otology, Rhinology &Laryngology, Ahead of Print. Objectives:Too little is known about hearing loss rehabilitation in patients with Alström syndrome (AS). Benefits of hearing aids (HA) have not been fully documented and only one case treated with a Cochlear Implant (CI) has been described in the proceedings of a conference. Furthermore, comorbidities and risk of complications following surgical intervention may contraindicate Cochlear Implant procedures...
Bitter Taste Perception of the Human Tongue Mediated by Quinine and Caffeine Impregnated Taste Strips: Annals of Otology, Rhinology &Laryngology, Ahead of Print. Objectives:Tests for gustatory function have become increasingly important in diagnosis and treatment of patients with taste disorders. While caffeine and quinine hydrochloride solutions have been used for global testing of bitter perception, only quinine has been used to test regional bitter perception by means of taste strips. The...
Congenital Midline Cervical Cleft: First Report and Genetic Analysis of Two Related Patients: Annals of Otology, Rhinology &Laryngology, Ahead of Print. Objectives:Congenital midline cervical cleft (CMCC) is a rare congenital anterior neck anatomical anomaly. We present the case of two related patients (grandchild and maternal grandmother) who were both born with a congenital midline cervical cleft along with genetic analysis.Methods:Clinical examination of both patients and surgical excision...
Effect of Over the Counter Ibuprofen Dosing after Sinus Surgery for Chronic Rhinosinusitis: A Prospective Cohort Pilot Study: Annals of Otology, Rhinology &Laryngology, Ahead of Print. Introduction:Management of pain following endoscopic sinus surgery (ESS) often involves intermittent use of opioid medications. Given the current opioid crisis, many surgeons aim to minimize opioid prescriptions. However, surgeons often avoid the use of NSAIDs following ESS out of concern for increased bleeding...
Survival Outcomes and Prognostic Factors of Open Partial Laryngeal Surgery: A Thirty Years' Experience: Annals of Otology, Rhinology &Laryngology, Ahead of Print. Background:Open partial laryngeal surgery (OPLS) represents a wide array of procedures that can be fitted to treat different types of laryngeal cancer (LC). We would like to present our 30-years' institutional experience, to analyze survival outcomes and to critically discuss prognostic factors.Methods:We reviewed all cases of OPLS...
Melanoma Characteristics in Patients with a History of UV Tanning Bed Usage: Annals of Otology, Rhinology &Laryngology, Ahead of Print. Objective:The purpose of this study was to evaluate the effect of tanning bed use on the behavior of subsequent melanomas.Methods:Cases of invasive cutaneous melanoma who completed a baseline questionnaire within 1 year of biopsy were ascertained using an institutional registry. Patients were categorized into one of two groups: (1) no history of UV tanning bed...
Using a 4K-3D Exoscope for Upper Airway Stimulation Surgery: Proof-of-Concept: Annals of Otology, Rhinology &Laryngology, Ahead of Print. Objective:Demonstrate the potential of the 4K-3D exoscope during upper airway stimulation surgery (UAS).Methods:A proof-of-concept study was performed to evaluate the feasibility of the exoscope during three consecutive UAS.Results:The exoscope was employed during UAS including cuff electrode and sensing lead placement. Three cases were successfully completed...
Gastropharyngeal Anastomotic Leak in Medullary Thyroid Carcinoma Following Initiation of a Tyrosine Kinase Inhibitor: A Case Report of an Unusual Side Effect of Cabozantinib: Annals of Otology, Rhinology &Laryngology, Ahead of Print. Background:Medullary thyroid carcinoma (MTC) accounts for 1% to 2% of thyroid cancers in the United States. When identified early, total thyroidectomy is most often curative. However, in advanced disease, more aggressive treatment such as laryngectomy and esophagectomy...
RELINF: prospective epidemiological registry of lymphoid neoplasms in Spain. A project from the GELTAMO group: AbstractLymphomas are a large, heterogeneous group of neoplasms with well-defined characteristics, and this heterogeneity highlights the importance of epidemiological data. Knowledge of local epidemiology is essential to optimise resources, design clinical trials, and identify minority entities. Given there are few published epidemiological data on lymphoma in Spain, the Spanish Lymphoma...
Safety and efficacy of blinatumomab: a real world data: AbstractDespite improvement in survival of newly diagnosed adult precursor B-acute lymphoblastic leukemia/lymphoma (B-ALL), the results of relapsed/refractory disease are poor. Blinatumomab, a bispecific monoclonal antibody directed against CD19/CD3 show clinical activity against relapsed/refractory B-ALL and in minimal residual disease (MRD)-positive patients.We report our "real-world" experience with blinatumomab in patients with relapsed/refractory...
The Role of Mobile Phone Camera Recordings in the Diagnosis of Meniere's Disease and Pathophysiological Implications.: Related ArticlesThe Role of Mobile Phone Camera Recordings in the Diagnosis of Meniere's Disease and Pathophysiological Implications.J Int Adv Otol. 2020 Feb 18;:Authors: Kıroğlu M, Dağkıran MAbstract OBJECTIVES: This study aimed to understand if videos of the patients' nystagmus recorded by themselves during the attacks can help in the diagnosis of Meniere's disease (MD)....
Recognizing Decompensated Meniere's Disease Using High Frequency Rotational Test.: Related ArticlesRecognizing Decompensated Meniere's Disease Using High Frequency Rotational Test.J Int Adv Otol. 2020 Feb 18;:Authors: Gökgöz MC, Satar B, Hıdır Y, Ceyhan A, Çoban VKAbstract OBJECTIVES: The purpose of this study is to investigate the effectiveness of the high-frequency rotational test for discrimination of patients with decompensated from those with compensated Meniere's disease. MATERIALS...
Myxoma Arising from the Middle Ear: A Case Report.: Related ArticlesMyxoma Arising from the Middle Ear: A Case Report.J Int Adv Otol. 2020 Feb 18;:Authors: Ülkü ÇH, Aydoğdu D, Erdem R, Esen HAbstract The primary head and neck myxomas are rare, generally arising from the mandible, maxilla, and oral cavity. Other anatomical areas, such as cardiac myxomas, may also have metastases to the head and neck regions. The middle ear is an extremely rare location for myxomas. Myxoma slowly grows and...
Human Epidermal Growth Factor Receptor 2 (HER2) in Advanced Gastric Cancer: Current Knowledge and Future Perspectives: AbstractThe discovery of human epidermal growth factor receptor 2 (HER2) overexpression in 15–20% of gastric adenocarcinomas has been a key advance in the global care of this disease. Validated by the ToGA trial in the first-line setting of advanced HER2-positive (+) gastric cancer (GC), trastuzumab, an anti-HER2 monoclonal antibody (mAb), was the first therapeutic agent to significantly...
TSLP Inhibitors for Asthma: Current Status and Future Prospects: AbstractThymic stromal lymphopoietin (TSLP) is an allarmin cytokine whose importance in human asthma has been repeatedly documented. Accordingly, targeting of TSLP and TSLP-mediated signalling is considered as an attractive therapeutic strategy to asthma. Tezepelumab, which is the first-in-class anti-TSLP monoclonal antibodies (mAb), is a fully human IgG2λ mAb that binds human TSLP, prevents interaction with its receptor and, consequently,...
Assessment of Vestibular Function in Adults with Prelingual Hearing Loss Using c/oVEMP Tests.: Related ArticlesAssessment of Vestibular Function in Adults with Prelingual Hearing Loss Using c/oVEMP Tests.J Int Adv Otol. 2020 Feb 18;:Authors: Tanyeri O, Akdoğan MV, Hızal E, Büyüklü AFAbstract OBJECTIVES: The aim of the present study was to compare the vestibular system integrity of individuals with normal hearing with that of prelingual hearing impaired individuals. It is well known that ocular...
Effect of Laryngeal Suspension and Upper Esophageal Sphincter Myotomy for Severe Dysphagia Due to Brainstem Disease: Annals of Otology, Rhinology &Laryngology, Ahead of Print. Objectives:Surgical procedure is considered in patients with severe dysphagia when conservative treatment fails. This study aimed to evaluate laryngeal suspension (LS) and upper esophageal sphincter (UES) myotomy for treating severe dysphagia due to brain disease.Methods:Fourteen patients underwent LS and UES myotomy, with...
Cricoid Chondronecrosis: Case Report and Review of Literature: Annals of Otology, Rhinology &Laryngology, Ahead of Print. Objective:Cricoid chondronecrosis is a rare entity that has significant consequences for patients. Reports of its occurrence are scattered in the literature and currently there is no comprehensive review to help guide providers.Methods:A case report from our institution is presented. A review of available literature is then provided with assessment of risk factors, signs and...
Paraclinical cardiac findings of children with breath-holding Spells in Taleghani Hospital of Gorgan, Iran, during 2014–2016: Hassan Esmaeili, Seyyed Ahmad Hosseini, Maryam Montazeri, Zohre RahatabResearch in Cardiovascular Medicine 2019 8(4):94-98Context: Breath-holding spells (BHSs) are episodes of brief, involuntary cessation of breathing that occur in children in response to stimuli such as anger, frustration, fear, or injury. It occurs in about 0.1%–4.6% of healthy children. Although the etiology...
Immediate effect of yogic postures on autonomic neural responses: Anup De, Samiran MondalResearch in Cardiovascular Medicine 2019 8(4):106-113Aim: The aim of this study is to identify the autonomic responses after immediate yogasana practices. Materials and Methods: Ten male (n = 10) yoga practitioners having more than 8 years of experience in yogasana practice were selected as subjects. Before and after immediate practices of six specific yoga postures were assessed on three different consecutive...
How Aluminum Damages Your Brain: For years, I've warned that aluminum is a serious neurotoxic hazard involved in rising rates of autism and Alzheimer's disease (AD). I've also warned that vaccines are a significant source of such exposure, and may be one of the worst, since by injecting it, the aluminum bypasses your body's natural filtering and detoxification systems.My comments above were one of the reasons the self-appointed global arbiter of fake news, NewsGuard, refused to give us "green"...
nClinical and Pathological Analysis of Dermatofibrosarcoma Protuberans with Long-term Follow-up: Publication date: Available online 18 February 2020Source: Journal of Plastic, Reconstructive & Aesthetic SurgeryAuthor(s): Xiu Shi, Qian TanAbstractBackground: Dermatofibrosarcoma protuberans (DFSP) is a rare dermal sarcoma characterized by low-grade malignancy, slow infiltrative growth, local recurrence and rare distant metastases.Objective: Many international studies exist on DFSP, but limited...
EVALUATION OF NASAL PATHOLOGIES ACCOMPANYING RHINOPLASTY CASES AT OTORHINOLARYNGOLOGY AND PLASTIC, RECONSTRUCTIVE & AESTHETIC SURGERY CLINICS: Publication date: Available online 18 February 2020Source: Journal of Plastic, Reconstructive & Aesthetic SurgeryAuthor(s): Fatih Mehmet Hanege, Serdal Celik, Ayse Yasemin Gunduz, Tolga AksanAbstractBackground and ObjectivesRhinoplasty is a frequently performed surgical procedure. Besides an aesthetically successful outcome, determination of additional...
How Should Indocyanine Green Dye Angiography be Assessed to Best Predict Mastectomy Skin Flap Necrosis? A systematic review: Publication date: Available online 18 February 2020Source: Journal of Plastic, Reconstructive & Aesthetic SurgeryAuthor(s): Caroline Driessen, Tinna Harper Arnardóttir, Andres Rodriguez Lorenzo, Maria Rydevik ManiAbstractIntroductionThe incidence of skin flap necrosis after mastectomies is as high as 11-24%. Laser-assisted indocyanine green (ICG) angiography seems to be...
Robotic versus conventional nipple sparing mastectomy and immediate gel implant breast reconstruction in the management of breast cancer- A case control comparison study with analysis of clinical outcome, medical cost, and patient-reported cosmetic results.: Publication date: Available online 18 February 2020Source: Journal of Plastic, Reconstructive & Aesthetic SurgeryAuthor(s): Hung-Wen Lai, Shou-Tung Chen, Chi Wei Mok, Ying-Jen Lin, Hwa-Koon Wu, Shih-Lung Lin, Dar-Ren Chen, Shou-Jen KuoSynopsis:...
Role of Lymphatico Venular Anastomosis for Treatment of Lymphorrhea in Lower Limbs: Publication date: Available online 18 February 2020Source: Journal of Plastic, Reconstructive & Aesthetic SurgeryAuthor(s): Shuhei Yoshida, Yuichi Hamada, Isao Koshima, Hirofumi Imai, Toshio Uchiki, Ayano Sasaki, Yumio Fujioka, Shogo Nagamatsu, Kazunori Yokota, Mitsunobu Harima, Shuji YamashitaAbstractObjectiveOnce established, lymphorrhea typically persists and can present as an external lymphatic fistula. Lymphorrhea...
Allograft Alone vs. Allograft with Intramedullary Vascularized Fibular Graft for Lower Extremity Bone Cancer: A Systematic Review and Meta-Analysis: Publication date: Available online 18 February 2020Source: Journal of Plastic, Reconstructive & Aesthetic SurgeryAuthor(s): Sammy Othman, Jonathan T. Bricker, Saïd C. Azoury, Omar Elfanagely, Kristy L. Weber, Stephen J. KovachAbstractBackgroundLimb-salvage surgery has become a first-line treatment in the setting of lower extremity cancer. Despite...
Full-thickness total upper eyelid reconstruction with a lid switch flap and a reverse superficial temporal artery flap: Publication date: Available online 18 February 2020Source: Journal of Plastic, Reconstructive & Aesthetic SurgeryAuthor(s): Ken Yamashita, Takatoshi Yotsuyanagi, Asuka Sugai, Ayako Gonda, Arisa Kita, Ayaka Kitada, Masahiro Onuma, Mami KudoAbstarctBackground: Reconstruction of the upper eyelid with the same eyelid tissue is desirable due to the ability to achieve eye opening/closing...
Refining our knowledge of macrovascular arteriovenous shunts (MAS): anatomical and pathological studies: Publication date: Available online 19 February 2020Source: Journal of Plastic, Reconstructive & Aesthetic SurgeryAuthor(s): Damien Grinsell, Amrish K.S. Rajkomar, Warren M. Rozen, Kelvin W.D. RamseyAbstractBackgroundThe MAS (macrovascular arteriovenous shunt) connecting the deep inferior epigastric artery (DIEA) and superficial inferior epigastric vein (SIEV) in the abdominal wall has already...
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Multimorbidity in the elderly: Are we prepared for it!Sandeep GroverJournal of Geriatric Mental Health 2019 6(2):35-37Attitude toward psychotropic medications: A comparison of the elderly and adult patients with affective and psychotic disordersSandeep Grover, Aseem Mehra, Subho Chakrabarti, Ajit AvasthiJournal of Geriatric Mental Health 2019 6(2):38-45Background: Attitude toward psychotropic medications influences medication adherence. Although there are some data on attitude toward psychotropics...
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International Journal of DermatologyEarly ViewOnline Version of Record before inclusion in an issueClinicopathologic challengeA tale of a vegetative inflammatory umbilical plaqueNoureddine Litaiem MD, Sirine Boumaiza MD, Meriem Jones MD, Takwa Bacha MD, Maroua Slouma MD, Sami Guetat MD, Soumaya Rammeh MD, PhD, Faten Zeglaoui MD, PhDVersion of Record online: 14 February 2020CorrespondenceSudden onset psoriasis causing eruptive seborrheic keratosesKathryn Lynam MD, Fatima Fahs MD, Steven Daveluy MDVersion...
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