Δευτέρα 11 Ιουλίου 2016
Abandoning use of 1st generation SAD – a reply
from #AlexandrosSfakianakis via Alexandros G.Sfakianakis on Inoreader http://ift.tt/29sD19R
via IFTTT
Cadaveric training – the solution for ultrasound-guided regional anaesthesia?
from #AlexandrosSfakianakis via Alexandros G.Sfakianakis on Inoreader http://ift.tt/29GVqU6
via IFTTT
Perineural or intravenous dexamethasone: do we still need catheters?
from #AlexandrosSfakianakis via Alexandros G.Sfakianakis on Inoreader http://ift.tt/29sD4T6
via IFTTT
Do I need ethics for this?
from #AlexandrosSfakianakis via Alexandros G.Sfakianakis on Inoreader http://ift.tt/29GVljp
via IFTTT
Propofol infusion in children
from #AlexandrosSfakianakis via Alexandros G.Sfakianakis on Inoreader http://ift.tt/29sD2e0
via IFTTT
Abandoning first generation supraglottic airway devices
from #AlexandrosSfakianakis via Alexandros G.Sfakianakis on Inoreader http://ift.tt/29GVqDA
via IFTTT
Propofol infusion in children – a reply
from #AlexandrosSfakianakis via Alexandros G.Sfakianakis on Inoreader http://ift.tt/29sDglf
via IFTTT
Hyaluronic acid fillers and hyaluronidase use in regional eye blocks
from #AlexandrosSfakianakis via Alexandros G.Sfakianakis on Inoreader http://ift.tt/29GVljw
via IFTTT
A randomised placebo-controlled trial examining the effect on hand supination after the addition of a suprascapular nerve block to infraclavicular brachial plexus blockade
Summary
Some surgeons believe that infraclavicular brachial plexus blocks tends to result in supination of the hand/forearm, which may make surgical access to the dorsum of the hand more difficult. We hypothesised that this supination may be reduced by the addition of a suprascapular nerve block. In a double-blind, randomised, placebo-controlled study, our primary outcome measure was the amount of supination (as assessed by wrist angulation) 30 min after infraclavicular brachial plexus block, with (suprascapular group) or without (control group) a supplementary suprascapular block. All blocks were ultrasound-guided. The secondary outcome measure was an assessment by the surgeon of the intra-operative position of the hand. Considering only patients with successful nerve blocks, mean (SD) wrist angulation was lower (33 (27) vs. 61 (44) degrees; p = 0.018) and assessment of the hand position was better (11/11 vs. 6/11 rated as ‘good’; p = 0.04) in the suprascapular group. The addition of a suprascapular nerve block to an infraclavicular brachial plexus block can provide a better hand/forearm position for dorsal hand surgery.
from #AlexandrosSfakianakis via Alexandros G.Sfakianakis on Inoreader http://ift.tt/29sD1H5
via IFTTT
Issue Information – Editorial Board
from #AlexandrosSfakianakis via Alexandros G.Sfakianakis on Inoreader http://ift.tt/29GVmUC
via IFTTT
Risk of bias and methodological appraisal practices in systematic reviews published in anaesthetic journals: a meta-epidemiological study
Summary
The validity of primary study results included in systematic reviews plays an important role in drawing conclusions about intervention effectiveness and carries implications for clinical decision-making. We evaluated the prevalence of methodological quality and risk of bias assessments in systematic reviews published in the five highest-ranked anaesthesia journals since 2007. The initial PubMed search yielded 315 citations, and our final sample after screening consisted of 207 systematic reviews. One hundred and seventy-four reviews conducted methodological quality/risk of bias analyses. The Jadad scale was most frequently used. Forty-four of the 83 reviews that included high risk of bias studies re-analysed their data omitting these trials: 20 showed differences in pooled effect estimates. Reviews containing a greater number of primary studies evaluated quality less frequently than smaller reviews. Overall, the majority of reviews evaluated bias; however, many applied questionable methods. Given the potential effects of bias on summary outcomes, greater attention is warranted.
from #AlexandrosSfakianakis via Alexandros G.Sfakianakis on Inoreader http://ift.tt/29sD3yA
via IFTTT
Our latest Special Issue provides an update on rapidly evolving developments in palliative cancer care in Africa: https://t.co/qNzEZ96GBV
from #AlexandrosSfakianakis via Alexandros G.Sfakianakis on Inoreader http://twitter.com/ecancer/status/752447937377075200
via IFTTT
Last chance for @uicc International Cancer Study Grants - deadline 15th July https://t.co/ZYCVGBhfXb https://t.co/vV8wkBN6kl
from #AlexandrosSfakianakis via Alexandros G.Sfakianakis on Inoreader http://twitter.com/ecancer/status/752437348269522944
via IFTTT
Prevalence and risk factors of chronic rhinosinusitis in South Korea according to diagnostic criteria.
Prevalence and risk factors of chronic rhinosinusitis in South Korea according to diagnostic criteria.
Rhinology. 2016 Jul 10;
Authors: Kim JH, Cho C, Lee EJ, Suh YS, Choi BI, Kim KS
Abstract
BACKGROUND: We aimed to compare the prevalence and risk factors of chronic rhinosinusitis (CRS) using two different diagnostic criteria with the same statistical data from the Korean National Health and Nutrition Examination Survey in 2009.
METHODS: Symptom-based CRS was defined as CRS diagnosed by questionnaires related to nasal symptoms. Endoscopy-based CRS was defined based on endoscopic findings and nasal symptoms of symptom-based CRS.
RESULTS: The overall prevalence of CRS based on the different diagnostic criteria was as follows: symptom-based CRS was 10.78% (797 of 7,394) and endoscopy-based CRS was 1.20% (88 of 7,343). Comparing symptom-based CRS to endoscopy-based CRS showed slight agreement (kappa = 0.183 (0.150-0.216, 95% confidence interval)). Allergic rhinitis was identified as a common risk factor for CRS based on the two diagnostic criteria.
CONCLUSIONS: The prevalence and risk factors of CRS were quite different from each other according to the different criteria, even in the same population. Therefore, it would be important to consider what specific diagnostic criteria have been adopted in the studies comparing the prevalence of CRS.
PMID: 27395040 [PubMed - as supplied by publisher]
from #AlexandrosSfakianakis via Alexandros G.Sfakianakis on Inoreader http://ift.tt/29P1BHf
via IFTTT
The in vitro effect of xylitol on chronic rhinosinusitis biofilms.
The in vitro effect of xylitol on chronic rhinosinusitis biofilms.
Rhinology. 2016 Jul 10;
Authors: Jain R, Lee T, Hardcastle T, Biswas K, Radcliff F, Douglas R
Abstract
INTRODUCTION: Biofilms have been implicated in chronic rhinosinusitis (CRS) and may explain the limited efficacy of antibiotics. There is a need to find more effective, non-antibiotic based therapies for CRS. This study examines the effects of xylitol on CRS biofilms and planktonic bacteria.
METHODS: Crystal violet assay and spectrophotometry were used to quantify the effects of xylitol (5% and 10% solutions) against Staphylococcus epidermidis, Pseudomonas aeruginosa, and Staphylococcus aureus. The disruption of established biofilms, inhibition of biofilm formation and effects on planktonic bacteria growth were investigated and compared to saline and no treatment.
RESULTS: Xylitol 5% and 10% significantly reduced biofilm biomass (S. epidermidis), inhibited biofilm formation (S. aureus and P. aeruginosa) and reduced growth of planktonic bacteria (S. epidermidis, S. aureus, and P. aeruginosa). Xylitol 5% inhibited formation of S. epidermidis biofilms more effectively than xylitol 10%. Xylitol 10% reduced S. epidermidis planktonic bacteria more effectively than xylitol 5%. Saline, xylitol 5% and 10% disrupted established biofilms of S. aureus when compared with no treatment. No solution was effective against established P. aeruginosa biofilm.
CONCLUSIONS: Xylitol has variable activity against biofilms and planktonic bacteria in vitro and may have therapeutic efficacy in the management of CRS.
PMID: 27394715 [PubMed - as supplied by publisher]
from #AlexandrosSfakianakis via Alexandros G.Sfakianakis on Inoreader http://ift.tt/29ILpnU
via IFTTT
Study finds no substantial harm from primary care melanoma screening
from #AlexandrosSfakianakis via Alexandros G.Sfakianakis on Inoreader http://ift.tt/29yqdlu
via IFTTT
IJMS, Vol. 17, Pages 1108: MAL Daylight Photodynamic Therapy for Actinic Keratosis: Clinical and Imaging Evaluation by 3D Camera
from #AlexandrosSfakianakis via Alexandros G.Sfakianakis on Inoreader http://ift.tt/29OVUZJ
via IFTTT
IJMS, Vol. 17, Pages 1103: Strawberry Achenes Are an Important Source of Bioactive Compounds for Human Health
from #AlexandrosSfakianakis via Alexandros G.Sfakianakis on Inoreader http://ift.tt/29IE4ov
via IFTTT
IJMS, Vol. 17, Pages 1105: Nuclear Receptor Regulation of Aquaporin-2 in the Kidney
from #AlexandrosSfakianakis via Alexandros G.Sfakianakis on Inoreader http://ift.tt/29OVQZS
via IFTTT
IJMS, Vol. 17, Pages 1102: Inhibition of AQP1 Hampers Osteosarcoma and Hepatocellular Carcinoma Progression Mediated by Bone Marrow-Derived Mesenchymal Stem Cells
from #AlexandrosSfakianakis via Alexandros G.Sfakianakis on Inoreader http://ift.tt/29IFcYY
via IFTTT
Issue 4 for volume 22 is out
from #AlexandrosSfakianakis via Alexandros G.Sfakianakis on Inoreader http://ift.tt/29r36dR
via IFTTT
Intraductal injection as an effective drug delivery route in the management of salivary gland diseases.
Intraductal injection as an effective drug delivery route in the management of salivary gland diseases.
Eur Arch Otorhinolaryngol. 2016 Jul 9;
Authors: Su CH, Lee KS, Tseng TM, Tseng H, Ding YF, Koch M, Hung SH
Abstract
While conservative approaches for chronic sialoadenitis are in current use, the utility of intraductal injection therapy remains unclear. The purpose of this study is to provide evidence that substances delivered through intraductal injection of the salivary gland are able to be effectively distributed throughout the gland. Methylene blue dye (0.1 %) was injected intraductally into a porcine parotid gland (5 ml) of one group and the porcine submandibular gland (1 or 2 ml, n = 6 for each preparation) of another group. After the injection, the ductal systems were evaluated, sectioned, and observed microscopically. Color area analysis was performed on submandibular gland sections, and the infiltration ratio of the dye was calculated. The papillae of both Stensen's and Wharton's duct openings were easily identified with intraductally delivered methylene blue dye. The dye infiltration began from the central ductal region of the gland and could be easily observed to gradually disperse to the peripheral regions in each acinar. There were no statistically significant differences in infiltration ratios between anterior, midline, and posterior section of the submandibular gland. Also, there were no statistically significant differences in the ratios between 1 and 2 ml injections at all the three section positions. This study demonstrated that desired substances can be evenly delivered throughout the salivary gland through intraductal injections. The use of intraductal injections might serve as a potential therapeutic procedure in the management of salivary gland diseases.
PMID: 27395068 [PubMed - as supplied by publisher]
from #AlexandrosSfakianakis via Alexandros G.Sfakianakis on Inoreader http://ift.tt/29OV6Ee
via IFTTT
Myeloid Sarcoma: Presenting with Massive Cervical and Inguinal Lymphadenopathy.
Myeloid Sarcoma: Presenting with Massive Cervical and Inguinal Lymphadenopathy.
Head Neck Pathol. 2016 Jul 9;
Authors: Walsh JC, Arnold MG, Mohtashamian A
Abstract
A 21 year old Active Duty Marine presented with acute onset of diffuse lymphadenopathy and B-symptoms. Biopsy was conducted which demonstrated myeloid sarcoma. Myeloid sarcoma is diagnostic for AML but is only present in 2-8 % of patients with AML. Our article presents a classic presentation and histologic appearance and discusses the current status of the literature.
PMID: 27395055 [PubMed - as supplied by publisher]
from #AlexandrosSfakianakis via Alexandros G.Sfakianakis on Inoreader http://ift.tt/29IDG9l
via IFTTT
Gain-switched 311-nm Ti:Sapphire laser might be a potential treatment modality for atopic dermatitis.
Gain-switched 311-nm Ti:Sapphire laser might be a potential treatment modality for atopic dermatitis.
Lasers Med Sci. 2016 Jul 9;
Authors: Choi SY, Oh CT, Kwon TR, Kwon HJ, Choi EJ, Jang YJ, Kim HS, Chu H, Mun SK, Kim MN, Kim BJ
Abstract
Phototherapy with 311-nm narrowband-UVB (NBUVB) is an effective adjuvant treatment modality for atopic dermatitis (AD). In this study, we evaluated the therapeutic effect of the newly developed gain-switched 311-nm Ti:Sapphire laser device using a NC/Nga mouse AD model. A total number of 50 mice were used in this study. Atopic dermatitis (AD) was induced in mice by exposure to Dermatophagoides farina. These, NC/Nga mice were then treated with conventional 311-nm NBUVB or the newly developed gain-switched 311-nm Ti:Sapphire laser. The clinical features, dermatitis severity scores, and scratching behavior were assessed. In addition, serologic analyses including inflammatory cytokines and histological analyses were performed. Gain-switched 311-nm Ti:Sapphire laser improved the AD-like skin lesions, severity, and symptoms of AD in the NC/Nga mouse model. This new laser also modulated the immune response found in the AD model, including hyper-IgE, upregulated Th2 cytokines, and the Th2-mediated allergic inflammatory reaction. Gain-switched 311-nm Ti:Sapphire laser shows therapeutic promise via an immune-modulation mechanism in an AD mouse model. These data suggest that gain-switched 311-nm Ti:Sapphire laser may be useful as a targeted phototherapy modality for AD.
PMID: 27394442 [PubMed - as supplied by publisher]
from #AlexandrosSfakianakis via Alexandros G.Sfakianakis on Inoreader http://ift.tt/29OVd2H
via IFTTT
Object-Based Distinction between Building Shadow and Water in High-Resolution Imagery Using Fuzzy-Rule Classification and Artificial Bee Colony Optimization
from #AlexandrosSfakianakis via Alexandros G.Sfakianakis on Inoreader http://ift.tt/29r00Xo
via IFTTT
Detecting Safety Zone Drill Process Parameters for Uncoated HSS Twist Drill in Machining GFRP Composites by Integrating Wear Rate and Wear Transition Mapping
from #AlexandrosSfakianakis via Alexandros G.Sfakianakis on Inoreader http://ift.tt/29OR3rx
via IFTTT
Factors in Gestational Diabetes Mellitus Predicting the Needs for Insulin Therapy
from #AlexandrosSfakianakis via Alexandros G.Sfakianakis on Inoreader http://ift.tt/29IywKL
via IFTTT
BeiDou Satellites Assistant Determination by Receiving Other GNSS Downlink Signals
from #AlexandrosSfakianakis via Alexandros G.Sfakianakis on Inoreader http://ift.tt/29OR1Qj
via IFTTT
Optimal Method for Catastrophic Faults Diagnosis in RC Ladder Network
from #AlexandrosSfakianakis via Alexandros G.Sfakianakis on Inoreader http://ift.tt/29Iz43b
via IFTTT
Implications of Hydrogen Sulfide in Glucose Regulation: How H2S Can Alter Glucose Homeostasis through Metabolic Hormones
from #AlexandrosSfakianakis via Alexandros G.Sfakianakis on Inoreader http://ift.tt/29OQYnI
via IFTTT
Sleep Spindles as an Electrographic Element: Description and Automatic Detection Methods
from #AlexandrosSfakianakis via Alexandros G.Sfakianakis on Inoreader http://ift.tt/29IyTVj
via IFTTT
Comorbid Illness, Bowel Preparation, and Logistical Constraints Are Key Reasons for Outpatient Colonoscopy Nonattendance
from #AlexandrosSfakianakis via Alexandros G.Sfakianakis on Inoreader http://ift.tt/29OQT3d
via IFTTT
Come celebrate the best of Welsh cancer research in with us in Cardiff. Email editor@ecancer .org to save your place! https://t.co/HRW3FHLSaZ
from #AlexandrosSfakianakis via Alexandros G.Sfakianakis on Inoreader http://twitter.com/ecancer/status/752426906167959552
via IFTTT
Discovery of new ovarian cancer signaling hub points to target for limiting metastasis: https://t.co/1cUoaY7qlx
from #AlexandrosSfakianakis via Alexandros G.Sfakianakis on Inoreader http://twitter.com/ecancer/status/752417770311155712
via IFTTT
A prospective randomised trial comparing insertion success rate and incidence of catheterisation-related complications for subclavian venous catheterisation using a thin-walled introducer needle or a catheter-over-needle technique
Summary
In clinical practice, both a thin-walled introducer needle and catheter-over-needle technique can be used to allow insertion of a guidewire during central venous catheterisation using the Seldinger technique. We compared the incidence of catheterisation-related complications (arterial puncture, haemothorax, pneumothorax, haematoma and catheter tip malposition) and insertion success rate for these two techniques in patients requiring right-sided subclavian central venous catheterisation. A total of 414 patients requiring infraclavicular subclavian venous catheterisation were randomly allocated to either a thin-walled introducer needle (needle group, n = 208) or catheter-over-needle technique (catheter group, n = 206). The catheterisation-related complication rate was lower in the needle group compared with the catheter group (5.8% vs. 15.5%; p = 0.001). Overall insertion success rates were similar (97.1% and 92.7% in the needle and catheter groups respectively; p = 0.046), although the first-pass success rate was higher in the needle group (62.0% vs. 35.4%; p < 0.001). We recommend the use of a thin-walled introducer needle technique for right-sided infraclavicular subclavian venous catheterisation.
from #AlexandrosSfakianakis via Alexandros G.Sfakianakis on Inoreader http://ift.tt/29yHtpd
via IFTTT
Total Protein Profile and Drug Resistance in Candida albicans Isolated from Clinical Samples
from #AlexandrosSfakianakis via Alexandros G.Sfakianakis on Inoreader http://ift.tt/29yEVaI
via IFTTT
Impact of Dental Implant Surface Modifications on Osseointegration
from #AlexandrosSfakianakis via Alexandros G.Sfakianakis on Inoreader http://ift.tt/29uwk75
via IFTTT
Two Case Reports on Thalamic and Basal Ganglia Involvement in Children with Dengue Fever
from #AlexandrosSfakianakis via Alexandros G.Sfakianakis on Inoreader http://ift.tt/29xnNpO
via IFTTT
The Stegosaurus Plate Controversy
-- Read more on ScientificAmerican.com
from #AlexandrosSfakianakis via Alexandros G.Sfakianakis on Inoreader http://ift.tt/29slFKt
via IFTTT
Meet the world’s cutest and most endangered animals
from #AlexandrosSfakianakis via Alexandros G.Sfakianakis on Inoreader http://ift.tt/29ORePL
via IFTTT
Therapeutic effect of apatinib-loaded nanoparticles on diabetes-induced retinal vascular leakage
from #AlexandrosSfakianakis via Alexandros G.Sfakianakis on Inoreader http://ift.tt/29CfJSj
via IFTTT
Cosmetics, Vol. 3, Pages 23: Sensitization and Clinically Relevant Allergy to Hair Dyes and Clothes from Black Henna Tattoos: Do People Know the Risk? An Uncommon Serious Case and a Review of the Literature
from #AlexandrosSfakianakis via Alexandros G.Sfakianakis on Inoreader http://ift.tt/29OqmmE
via IFTTT
Meet the world’s cutest and most endangered animals
from #AlexandrosSfakianakis via Alexandros G.Sfakianakis on Inoreader http://ift.tt/29ORePL
via IFTTT
The cancer stem-cell signaling network and resistance to therapy
Source:Cancer Treatment Reviews
Author(s): A. Carnero, Y. Garcia-Mayea, C. Mir, J. Lorente, I.T. Rubio, M.E. LLeonart
The study of cancer stem cells (CSCs) has shown that tumors are driven by a subpopulation of self-renewing CSCs that retain the capacity to engender the various differentiated cell populations that form tumors. The characterization of CSCs has indicated that CSCs are remarkably resistant to conventional radio- and chemo-therapy. Clinically, the remaining populations of CSC are responsible for metastasis and recurrence in patients with cancer, which can lead to the disease becoming chronic and incurable. Therefore, the elimination of CSCs is an important goal of cancer treatments. Furthermore, CSCs are subject to strong regulation by the surrounding microenvironment, which also impacts tumor responses. In this review, we discuss the mechanisms by which pathways that are defective in CSCs influence ultimately therapeutic and clinical outcomes.
Graphical abstract
from #AlexandrosSfakianakis via Alexandros G.Sfakianakis on Inoreader http://ift.tt/29Gtksn
via IFTTT
Bilateral Postoperative Cyst after Maxillary Sinus Surgery: Report of a Case and Systematic Review of the Literature
from #AlexandrosSfakianakis via Alexandros G.Sfakianakis on Inoreader http://ift.tt/29yw34Q
via IFTTT
Incidence, Prevalence, and Mortality Trends in Chronic Obstructive Pulmonary Disease over 2001 to 2011: A Public Health Point of View of the Burden
from #AlexandrosSfakianakis via Alexandros G.Sfakianakis on Inoreader http://ift.tt/29xffPU
via IFTTT
Alternative Confidence Interval Methods Used in the Diagnostic Accuracy Studies
from #AlexandrosSfakianakis via Alexandros G.Sfakianakis on Inoreader http://ift.tt/29yvBnj
via IFTTT
Accessibility to, Acceptability of, and Adherence to HIV/AIDS Prevention Services by Men Who Have Sex with Men: Challenges Encountered at Facility Level
from #AlexandrosSfakianakis via Alexandros G.Sfakianakis on Inoreader http://ift.tt/29xfomu
via IFTTT
Spectral Analysis of Chinese Medicinal Herbs Based on Delayed Luminescence
from #AlexandrosSfakianakis via Alexandros G.Sfakianakis on Inoreader http://ift.tt/29yvNTD
via IFTTT
Etodolac Containing Topical Niosomal Gel: Formulation Development and Evaluation
from #AlexandrosSfakianakis via Alexandros G.Sfakianakis on Inoreader http://ift.tt/29xfwCs
via IFTTT
Δημοφιλείς αναρτήσεις
-
Background Hyperthyroidism is associated with increased thrombotic risk. As contact system activation through formation of neutrophil extrac...
-
UM-Chor1: establishment and characterization of the first validated clival chordoma cell line. J Neurosurg. 2017 Apr 21;:1-9 Authors:...
-
Impact of habitat loss and fragmentation on reproduction, dispersal and species persistence for an endangered Chilean tree Abstract Survival...
-
Publication date: Available online 10 May 2017 Source: Journal of Dairy Science Author(s): R.E. Vibart, M. Tavendale, D. Otter, B.H. Schw...
-
Competency-based psychiatric education for Indian medical undergraduates Vijayalakshmi Pernenkil Archives of Mental Health 2019 20(1):1-2 Be...
-
Related Articles Developmental control of macrophage function. Curr Opin Immunol. 2017 Dec 13;50:64-74 Authors: Bonnardel J, Guillia...
-
Kajal Manchanda, Sandip Mohanty, Pallavi C Rohatgi Indian Dermatology Online Journal 2017 8(3):186-191 Introduction: Topical corticoster...
-
Summary The preventive effect of coffee on cancer at different sites has been reported, although the effect on all-sites cancer incidence ...
-
from #AlexandrosSfakianakis via Alexandros G.Sfakianakis on Inoreader http://ift.tt/2tcPIjn via IFTTT