What is Health Services Research?

Publication date: Available online 7 April 2018
Source:Academic Radiology
Author(s): James V. Rawson, Paul Cronin




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An investigation on the seasonal variations of the biomarkers of oxidative stress response and their correlations to Polonium-210 in mussel (Mytilus galloprovincialis) and common sole (Solea solea) from İzmir Bay, Turkey

Publication date: September 2018
Source:Journal of Environmental Radioactivity, Volume 189
Author(s): Ersan Aslan, Aysun Uğur Görgün, Selma Katalay, Işık Filizok, Seda Becerik, Tülin Aydemir
It is well known that the marine organisms are used as biological indicators for environmental pollution studies. Among these studies, the research on oxidative stress has been increasing in recent years. In this study, mussels (Mytilus galloprovincialis) and fish (Solea solea) samples were collected seasonally from İnciraltı, İzmir, Turkey. This station was in an area where fishing is carried out for human consumption. The relationship between ²¹⁰Po and oxidative stress markers (lipid peroxidation (LPO), H2O2 and proline) was investigated in the mussel tissue (digestive gland, gills) and fish tissue (liver, gills) samples. The present study indicated that H2O2 accumulated with increasing ²¹⁰Po concentration in mussel samples. Statistically significant correlation were found between H2O2 and ²¹⁰Po and LPO and proline in mussel samples. This correlation between LPO and proline can be attributed to common environmental parameters (other than ²¹⁰Po) affecting expression of both LPO and proline levels. There was not a significant correlation between ²¹⁰Po and LPO levels. Similarly, a significant correlation was not found between ²¹⁰Po and proline.



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Intracranial Hypotension : MRI

Case Report: 27 year old female without any previous co-morbidity and not on any medications was diagnosed with hydatidiform mole. Evacuation was done under spinal anesthesia. The next day following the procedure, she developed headache, which was only present on sitting on standing and was relieved on attaining supine position. After 2 days , she developed worsening of the headache which now became continuous and  she also developed right sided focal seizures in upper limb. Initial clinical diagnosis in the background of a hypercoagulable state (hydatiform mole), headache and seizures was cerebral venous thrombosis. However, since she developed a typical positional headache after the procedure under spinal, possibility of CVT secondary to Idiopathic Intracranial Hypotension was also considered and MRI with contrast advised. Case Submitted by Dr Rahul Rajeev, DM (Neurology Std)

MRI Finding: MRI reveals pachymeningeal enhancement on the CEMR sections. Outstanding finding in the images is  venous distension sign and apparent rounding of the cross-section of the dural venous sinuses.  Prominence of inferior intercavernous sinuses also noted. Pituitary appears bulky. Splenium of corpus callosum is drooping down. These findings are consistent with intracranial hypotension probably secondary to lumbar puncture. Also noted are small filling defect (thrombus) in superior sagittal sinus extending towards left possibly explaining the seizures on the right side.   MRI discussion : Dr Sumer Sethi, MD Radiology

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