Working with animals: Implications for employees’ compassion, awe, prosocial behavior, and task performance

alexandrossfakianakis shared this article with you from Inoreader Working with animals: Implications for employees' compassion, awe, prosocial behavior, and task performance via Personnel Psychology Abstract Human-animal work represents a collaboration between humans and animals to achieve work goals, and is common in the domains of healthcare, therapy, entertainment, and education. Although the scopes and types of human-animal work is diversifying and increasing, organizational scholars have yet to explore its impacts on employees. Drawing from the models of compassion and mind perception theories, we first develop a theoretical model pertaining to the development of compassion as a result of human-animal work. In a study with zookeepers (Study 1), we find that human-animal work evokes the emotion of compassion, which in turn is positively associated with employee prosocial behavior and task performance. These mediated effects are moderated by how employees perceive animals – employees are more likely to experience compassion, and in turn become more prosocial and work better when they generally perceive animals to be able to experience emotions and bodily sensations. Furthermore, two follow-up studies (i.e., Studies 2 and 3) with employees who engage in human-animal work in Hong Kong and the United States reveal that working with animals evokes awe in addition to compassion, and provides insight into their resultant impact on prosocial behavior and task performance. We end by discussing the theoretical and practical implications of this work. This article is protected by copyright. All rights reserved View on Web

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Effects of Cortical Stimulation on Feedback‐Dependent Vocal Control in Non‐Human Primates

alexandrossfakianakis shared this article with you from Inoreader Effects of Cortical Stimulation on Feedback‐Dependent Vocal Control in Non‐Human Primates via The Laryngoscope Objectives Hearing plays an important role in our ability to control voice, and perturbations in auditory feedback result in compensatory changes in vocal production. The auditory cortex (AC) has been proposed as an important mediator of this behavior, but causal evidence is lacking. We tested this in an animal model, hypothesizing that AC is necessary for vocal self-monitoring and feedback-dependent control, and that altering activity in AC during vocalization will interfere with vocal control. Methods We implanted two marmoset monkeys (Callithrix jacchus) with bilateral AC electrode arrays. Acoustic signals were recorded from vocalizing marmosets while altering vocal feedback or electrically stimulating AC during random subsets of vocalizations. Feedback was altered by real-time frequency shifts and presented through headphones and electrical stimulation delivered to individual electrodes. We analyzed recordings to measure changes in vocal acoustics during shifted feedback and stimulation, and to determine their interaction. Results were correlated with the location and frequency tuning of stimulation sites. Results Consistent with previous results, we found electrical stimulation alone evoked changes in vocal production. Results were stronger in the right hemisphere, but decreased with lower currents or repeated stimulation. Simultaneous stimulation and shifted feedback significantly altered vocal control for a subset of sites, decreasing feedback compensation at some and increasing it at others. Inhibited compensation was more likely at sites closer to vocal frequencies. Conclusions Results provide causal evidence that the AC is involved in feedback-dependent vocal control, and that it is sufficient and may also be necessary to drive changes in vocal production. Level of Evidence N/A Laryngoscope, 2022 View on Web

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Correction to: Severe Dysbiosis and Specific Haemophilus and Neisseria Signatures as Hallmarks of the Oropharyngeal Microbiome in Critically Ill Coronavirus Disease 2019 (COVID-19) Patients

alexandrossfakianakis shared this article with you from Inoreader Correction to: Severe Dysbiosis and Specific Haemophilus and Neisseria Signatures as Hallmarks of the Oropharyngeal Microbiome in Critically Ill Coronavirus Disease 2019 (COVID-19) Patients via Clinical Infectious Diseases Advance Access Several errors appeared in supplementary data for the corrected proof publication of this article (de Castilhos J, Zamir E, Hippchen T, et al. Severe Dysbiosis and Specific Haemophilus and Neisseria Signatures as Hallmarks of the Oropharyngeal Microbiome in Critically Ill Coronavirus Disease 2019 [COVID-19] Patients. Clin Infect Dis; https://doi.org/10.1093/cid/ciab902). View on Web

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Antibody response of heterologous vs homologous mRNA vaccine boosters against the SARS-CoV-2 Omicron variant: interim results from the PRIBIVAC study, A Randomized Clinical Trial

alexandrossfakianakis shared this article with you from Inoreader Antibody response of heterologous vs homologous mRNA vaccine boosters against the SARS-CoV-2 Omicron variant: interim results from the PRIBIVAC study, A Randomized Clinical Trial via Clinical Infectious Diseases Advance Access Abstract Background Waning antibody levels post-vaccination and the emergence of variants of concern (VOCs) capable of evading protective immunity has raised the need for booster vaccinations. However, which combination of COVID-19 vaccines offers the strongest immune response against Omicron variant is unknown. Methods This randomized, subject-blinded, controlled trial assessed the reactogenicity and immunogenicity of different COVID-19 vaccine booster combinations. 100 BNT162b2-vaccinated individuals were enrolled and randomized 1: 1 to either homologous (BNT162b2 + BNT162b2 + BNT162b2; 'BBB') or heterologous mRNA booster vaccine (BNT162b2 + BNT162b2 + mRNA-1273; 'BBM'). Primary endpoint was the level of neutralizing antibodies against SARS-CoV-2 wild-type and VOCs at Day 28. Results 51 participants were allocated to BBB and 49 to BBM; 50 and 48 respectively were analyzed for safety and immunogenicity outcomes. At Day 28 post-boost, mean SARS-CoV-2 spike antibody titers were lower with BBB (22,382  IU/mL 95% CI, 18,210 to 27,517) vs BBM (29,751  IU/mL 95% CI, 25,281 to 35,011, p = 0.034) as was the median level of neutralizing antibodies: BBB 99.0% (IQR 97.9 to 99.3%) vs BBM 99.3% (IQR 98.8 to 99.5%, p = 0.021). On sub-group analysis, significant differences in mean spike antibody titer and live Omicron neutralization titer was only observed in older adults. Median surrogate neutralizing antibody level against all VOCs was also significantly higher with BBM in older adults, and against Omicron was BBB 72.8% (IQR 54.0 to 84.7%) vs BBM 84.3% (IQR 78.1 to 88.7%, p = 0.0073). Both vaccines were well tolerated. Conclusions Heterologous mRNA-1273 booster vaccination induced a stronger neutralizing response against the Omicron variant in older individuals compared with homologous BNT123b2. View on Web

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Bone targeted new zoledronate derivative: design, synthesis, 99mTc-coupling, in-silico study and preclinical evaluation for promising osteosarcoma therapy

alexandrossfakianakis shared this article with you from Inoreader Bone targeted new zoledronate derivative: design, synthesis, 99mTc-coupling, in-silico study and preclinical evaluation for promising osteosarcoma therapy via International Journal of Radiation Biology: Table of Contents: Taylor and Francis . View on Web

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Possible mechanisms and biomarkers of resistance to vismodegib in SHH medulloblastoma

alexandrossfakianakis shared this article with you from Inoreader Possible mechanisms and biomarkers of resistance to vismodegib in SHH medulloblastoma via Neuro-Oncology Advance Access National Council for Scientific and Technological Development10.13039/501100003593305647/2019-9201001/2014-4Children's Cancer InstituteWilliam Donald Nash Brain Tumour Research FellowshipBrain Tumour Foundation of Canada10.13039/501100000238Swifty Foundation10.13039/100017296North West Cancer Research10.13039/501100000357 View on Web

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Analysis of fractured dental implant body from five different implant systems: a long-term retrospective study

alexandrossfakianakis shared this article with you from Inoreader Analysis of fractured dental implant body from five different implant systems: a long-term retrospective study via International Journal of Oral and Maxillofacial Surgery via MedWorm.com The aim of this study was to perform an analysis of the incidence of implant body fracture and to identify possible risk factors. A long-term follow-up retrospective evaluation of 3477 patients who received 8588 implants from five implant systems was performed. Overall, 2810 patients who received 7502 implants, with an average follow-up of 6.9 years, were included in the analysis. The overall body fracture rate was 0.49% (37/7502), among which 32.4% (12/37) were implants with a reduced diameter. (Source: International Journal of Oral and Maxillofacial Surgery) View on Web

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