ANTI-DIABETIC ACTIVITY OF ETHANOLIC EXTRACT OF LONICERA QUINQUELOCULARIS LEAF ON WISTAR RATS

2016-10-16T02-20-53Z
Source: Indo American Journal of Pharmaceutical Research
P. Seetaram* G. Venkataiah, Humera Naaz.
The aim of this study is to evaluate the preliminary phytochemical screening and anti-diabetic activity of the ethanolic extract of lonicera quinquelocularis leaf extract in albino wistar rats. The ethanolic extract of lonicera quinquelocularis leaf was prepared using 97% ethanol 72 hrs by maceration and concentrated. The dose of 150 and 300 mg/kg of the extract was used the study activity. The extract of 300mg/kg shown significant decreased blood glucose levels from 3h in acute study and the both doses started decreasing blood glucose level from the 1st day in sub-acute study. As for the results gained it is concluded that the ethanolic extract of lonicera quinquelocularis leaf shown the presence of flavonoids, terpenoids, alkaloids, steroids and tannins and also has a potent significant anti-diabetic activity in wistar rats. Further examination is required to identify, purify the individual phytochemical constituents and evaluate for the anti-diabetic activity in different models.


http://ift.tt/2dFQuh2