Keratocystic odontogenic tumour (KCOT) is considered one of the most aggressive odontogenic lesions presenting high recurrence rate which varies according to treatment modalities employed for management. The treatment rendered should have a lowest possible risk of recurrence and least morbidity while still eradicating the lesion. Although the radical treatment options like enucleation and en bloc resection are associated with lesser recurrences, these can lead to greater morbidity, especially in children with developing teeth and jaw bones, thus, emphasising need to consider more conservative treatment options like decompression and marsupialisation. The purpose of this article was to report the case of an 11-year-old male child with KCOT in the mandibular region associated with impacted premolar treated successfully with decompression and intraoral appliance. After 24 months of follow-up, the spontaneous eruption of premolar was noted with complete resolution of periapical radiolucency. No recurrence was noted even after 5-year follow-up.
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