To exploit the full potential of proton therapy, accurate and on-line methods to verify the patient positioning and the proton range during the treatment are desirable. Here we propose and validate an innovative technique for determining patient misalignment uncertainties through the use of a small number of low dose, carefully selected proton pencil beams (‘range probes’) (RP) with sufficient energy that their residual Bragg peak (BP) position and shape can be measured on exit. Since any change of the patient orientation in relation to these beams will result in changes of the density heterogeneities through which they pass, our hypothesis is that patient misalignments can be deduced from measured changes in Bragg curve (BC) shape and range. As such, a simple and robust methodology has been developed that estimates average proton range and range dilution of the detected residual BC, in order to locate range probe positions with optimal prediction power for detecting misalignmen...
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Abstract Purpose Overcoming the flaws of current data management conditions in head and neck oncology could enable integrated informatio...
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ACS Nano DOI: 10.1021/acsnano.6b04244 from #AlexandrosSfakianakis via Alexandros G.Sfakianakis on Inoreader http://ift.tt/2aOZU8w via...
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JOURNAL OF JAPAN SOCIETY FOR SAFETY ENGINEERING_1998_5 from #AlexandrosSfakianakis via Alexandros G.Sfakianakis on Inoreader http://ift.tt...
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Vol.83 No.3 from #AlexandrosSfakianakis via Alexandros G.Sfakianakis on Inoreader http://ift.tt/1TkQfWM via IFTTT
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Small size of metastatic lymph nodes with extracapsular spread greatly impacts treatment outcomes in oral squamous cell carcinoma patie...
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Guidelines for inpatient admission after pediatric tonsillectomy have been proposed to improve the safety of this procedure. This study exam...
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Madhavi Bhargava Journal of Family and Community Medicine 2017 24(2):131-131 from #AlexandrosSfakianakis via Alexandros G.Sfakianakis ...
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