Historical perspective and nomenclature of potentially malignant or potentially premalignant oral epithelial lesions with emphasis on leukoplakia; some suggestions for modifications

Of the potentially (pre)maligant oral epithelial lesions leukoplakia is the most common one. A brief overview is presented of the various definitions of leukoplakia that have been used in the past. A proposal has been made to adjust the presently existing definition. Clinically, leukoplakias have been subdivided for decades in homogeneous and non-homogeneous leukoplakias, being further divided in different subtypes. A proposal has been made to slightly rearrange these subtypes. Furthermore, attention has been paid to a number of keratotic lesions that have been reported in the literature.

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