135 La has favorable nuclear and chemical properties for Auger-based targeted internal radiotherapy. Here we present detailed investigations of the production, emissions, and dosimetry related to 135 La therapy. 135 La was produced by 16.5 MeV proton irradiation of metallic nat Ba on a medical cyclotron, and was isolated and purified by trap-and-release on weak cation-exchange resin. The average production rate was 407 ± 19 MBq µ A −1 (saturation activity), and the radionuclidic purity was 98% at 20 h post irradiation. Chemical separation recovered > 98 % of the 135 La with an effective molar activity of 70 ± 20 GBq µ mol −1 . To better assess cellular and organ dosimetry of this nuclide, we have calculated the x-ray and Auger emission spectra using a Monte Carlo model accounting for effects of multiple vacancies during the Auger cascade. The generated Auger spectrum was used to calculate ...
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Abstract Purpose Overcoming the flaws of current data management conditions in head and neck oncology could enable integrated informatio...
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JOURNAL OF JAPAN SOCIETY FOR SAFETY ENGINEERING_1998_5 from #AlexandrosSfakianakis via Alexandros G.Sfakianakis on Inoreader http://ift.tt...
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Vol.83 No.3 from #AlexandrosSfakianakis via Alexandros G.Sfakianakis on Inoreader http://ift.tt/1TkQfWM via IFTTT
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Small size of metastatic lymph nodes with extracapsular spread greatly impacts treatment outcomes in oral squamous cell carcinoma patie...
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Guidelines for inpatient admission after pediatric tonsillectomy have been proposed to improve the safety of this procedure. This study exam...
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Madhavi Bhargava Journal of Family and Community Medicine 2017 24(2):131-131 from #AlexandrosSfakianakis via Alexandros G.Sfakianakis ...
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Publication date: Available online 14 May 2017 Source: Journal of Oral Biosciences Author(s): Hiromi Kimura-Suda, Teppi Ito BackgroundBo...
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