Background. Deep vein thrombosis (DVT) is one of the major complications of total joint arthroplasty (TJA). Chronic kidney dysfunction (CKD) has proven to promote a proinflammatory and prothrombotic state and is prevalent among patients undergoing TJA. The purpose of this study is to identify whether CKD increase the risk of DVT following TJA. Methods. In a retrospective study, 1274 patients who underwent primary TJA were studied. CKD is graded in 5 stages. Univariate and multivariate analysis were used to identify the association of CKD and its severity with postoperative DVT. Results. There were 1139 (89.4%) participants with normal kidney function, 103 (8.1%) with mildly decreased kidney function, and 32 (2.5%) with stage 3 and 4 CKD. A total of 244 patients (19.2%) were diagnosed with DVT. Sixty-four patients (5.0%) developed symptomatic DVT. Advanced age, female gender, malignancy, and eGFR showed significant association with total DVT. BMI, thrombosis history, malignancy, and eGFR were associated with symptomatic DVT. After adjusting for age, gender, BMI, and malignancy, eGFR was found to be related to both total and symptomatic DVT. Conclusions. CKD is an important risk factor for both total and symptomatic DVT following TJA. Postoperative prophylaxis should be made a priority in this population.
from #AlexandrosSfakianakis via Alexandros G.Sfakianakis on Inoreader http://ift.tt/2rsoLKU
via IFTTT
Εγγραφή σε:
Σχόλια ανάρτησης (Atom)
Δημοφιλείς αναρτήσεις
-
Abstract BACE1 is an indispensable enzyme for generating β-amyloid peptides, which are excessively accumulated in brains of Alzheimer'...
-
Publication date: Available online 23 April 2017 Source: Journal of Plastic, Reconstructive & Aesthetic Surgery Author(s): Yu-Jen Chiu...
-
Objective To identify the injury history features reported by patients with anterior cruciate ligament (ACL) injuries and determine whether ...
-
Rhinoplasty is perhaps the most challenging and elegant procedure within all of plastic surgery. In this issue of JAMA Facial Plastic Surger...
-
Science Daily Scientists develop light-controllable tool to study CaMKII kinetics in learning and memory Science Daily In summary, t...
-
AMEDEO Otorhinolaryngologyhttp://www.amedeo.comhttp://m.amedeo.com2019-10-07Your Personal Amedeo Web... AMEDEO Otorhinolaryngologyhttp://www...
-
Publication date: October 2017 Source: International Journal of Biological Macromolecules, Volume 103 Author(s): Sapna, Bijender Singh A...
-
Wood plastic composites (WPCs) are increasingly being utilized these days due to their excellent mechanical properties and low maintenance c...
-
Abstract Antisynthetase syndrome is a heterogeneous idiopathic inflammatory myopathy. Anti-Jo1 is the most common antibody found in this c...
Δεν υπάρχουν σχόλια:
Δημοσίευση σχολίου