The last decades witnessed the appearance of a series of new psychoactive substances (NPS) on the drug scene [1]. These new compounds have proven to be a serious challenge for legislators and health operators; indeed, by marketing them as items not for human consumption (such as ladybug attractant, plant food, bath salts)[2], the producers of such compounds effectively manage to circumvent the law, and to market “legal highs”[3]. Despite governments all over the world constantly update the lists of scheduled substances, new chemical structures keep hitting the market on an almost monthly basis, both in USA and in Europe[4].
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